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PE20011005A1 - COMBINATIONS OF A PHOSPHODIESTERASE 4 INHIBITOR AND A STEROID ANTI-INFLAMMATORY FOR THE TREATMENT OF PULMONARY DISEASES - Google Patents

COMBINATIONS OF A PHOSPHODIESTERASE 4 INHIBITOR AND A STEROID ANTI-INFLAMMATORY FOR THE TREATMENT OF PULMONARY DISEASES

Info

Publication number
PE20011005A1
PE20011005A1 PE2000001168A PE0011682000A PE20011005A1 PE 20011005 A1 PE20011005 A1 PE 20011005A1 PE 2000001168 A PE2000001168 A PE 2000001168A PE 0011682000 A PE0011682000 A PE 0011682000A PE 20011005 A1 PE20011005 A1 PE 20011005A1
Authority
PE
Peru
Prior art keywords
phosphodiesterase
inhibitor
pulmonary diseases
inflammatory
combinations
Prior art date
Application number
PE2000001168A
Other languages
Spanish (es)
Inventor
Peter N Goodfellow
Theodores J Torphy
Richard Nieman
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of PE20011005A1 publication Critical patent/PE20011005A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIERE AL USO DE UNA COMBINACION QUE COMPRENDE:UN INHIBIDOR DE FOSFODIESTERASA 4 (PDE 4) TAL COMO EL ACIDO CIS-4-CIANO-(3-CICLOPENTILOXI-4-METOXIFENIL)CICLOHEXANO-1-CARBOXILICO Y UN CORTICOIDE TAL COMO DEXAMETASONA, FLUTICASONA, BECLOMETASONA, BUDENOSINA, FLUNICOLIDA, FUROATO DE MOMETASONA, ACETONIDO DE TRIAMCINOLONA; LOS QUE SE ADMINISTRAN JUNTOS O POR SEPARADO. LA COMBINACION PUEDE SER UTIL PARA PREVENIR O REDUCIR ENFERMEDADES PULMONARESIT REFERS TO THE USE OF A COMBINATION THAT INCLUDES: A PHOSPHODIESTERASE 4 (PDE 4) INHIBITOR SUCH AS CIS-4-CYANE- (3-CYCLOPENTILOXY-4-METOXYPHENYL) CYCLOHEXAN-1-CARBOXAMYLONE ACID, AND A CORTICOID THAX FLUTICASONE, BECLOMETASONE, BUDENOSINE, FLUNICOLIDE, MOMETASONE FUROATE, TRIAMCINOLONE ACETONIDE; THOSE THAT ARE ADMINISTERED TOGETHER OR SEPARATELY. THE COMBINATION MAY BE USEFUL TO PREVENT OR REDUCE PULMONARY DISEASES

PE2000001168A 1999-11-02 2000-11-02 COMBINATIONS OF A PHOSPHODIESTERASE 4 INHIBITOR AND A STEROID ANTI-INFLAMMATORY FOR THE TREATMENT OF PULMONARY DISEASES PE20011005A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16315899P 1999-11-02 1999-11-02

Publications (1)

Publication Number Publication Date
PE20011005A1 true PE20011005A1 (en) 2001-09-28

Family

ID=22588737

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2000001168A PE20011005A1 (en) 1999-11-02 2000-11-02 COMBINATIONS OF A PHOSPHODIESTERASE 4 INHIBITOR AND A STEROID ANTI-INFLAMMATORY FOR THE TREATMENT OF PULMONARY DISEASES

Country Status (29)

Country Link
EP (1) EP1225866A4 (en)
JP (1) JP2003513028A (en)
KR (1) KR20020057988A (en)
CN (1) CN1387404A (en)
AP (1) AP2002002496A0 (en)
AR (1) AR029189A1 (en)
AU (1) AU1357501A (en)
BG (1) BG106748A (en)
BR (1) BR0015270A (en)
CA (1) CA2388333A1 (en)
CO (1) CO5261512A1 (en)
CZ (1) CZ20021512A3 (en)
DZ (1) DZ3225A1 (en)
EA (1) EA200200518A1 (en)
EC (1) ECSP003747A (en)
HK (1) HK1049107A1 (en)
HU (1) HUP0203152A3 (en)
IL (1) IL149367A0 (en)
MA (1) MA26841A1 (en)
MX (1) MXPA02004350A (en)
NO (1) NO20022057L (en)
OA (1) OA12076A (en)
PE (1) PE20011005A1 (en)
PL (1) PL355261A1 (en)
SK (1) SK7592002A3 (en)
TR (1) TR200201211T2 (en)
TW (1) TWI242431B (en)
WO (1) WO2001032127A2 (en)
ZA (1) ZA200203435B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003024489A2 (en) 2001-09-19 2003-03-27 Altana Pharma Ag Combination of a nsaid and a pde-4 inhibitor
US20040259863A1 (en) * 2001-10-31 2004-12-23 Hans-Michael Eggenweiler Type 4 phosphodiesterase inhibitors and uses thereof
UA82323C2 (en) * 2002-08-09 2008-04-10 Меда Фарма Гмбх & Ко. Кг Novel combination of a glucocorticoid and pde-inhibitor for the treatment of respiratory diseases, allergic diseases, asthma and chronic obstructive pulmonary diseases
TW200410923A (en) * 2002-10-17 2004-07-01 Ono Pharmaceutical Co Therapeutic agent for chronic obstructive pulmonary disease
EP1616569A1 (en) * 2003-03-31 2006-01-18 Kyowa Hakko Kogyo Co., Ltd. Medicinal composition
US20050026883A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a PDE-4 inhibitor for treatment of asthma or chronic obstructive pulmonary disease
US20070287689A1 (en) * 2004-10-13 2007-12-13 Kyowa Hakko Kogyo Co., Ltd. Therapeutic And/Or Preventive Agents For Chronic Skin Diseases
EP1948167A1 (en) * 2005-10-19 2008-07-30 Ranbaxy Laboratories, Ltd. Compositions of phosphodiesterase type iv inhibitors
JP6017961B2 (en) 2010-01-05 2016-11-02 マイクロドース セラピューテクス，インコーポレイテッド Inhalation device and method
WO2015063669A1 (en) 2013-10-30 2015-05-07 Wockhardt Limited Pharmaceutical compositions comprising combination of roflumilast and acebrophylline or pharmaceutically acceptable salts thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7174794A (en) * 1993-06-18 1995-01-17 Smithkline Beecham Corporation Compounds
DE4332041C2 (en) * 1993-09-21 1997-12-11 Rentschler Arzneimittel Use of pentoxifylline in certain lung diseases
PE44995A1 (en) * 1994-01-27 1995-12-18 Schering Corp MOMETASONE FUROATE FOR THE TREATMENT OF LUNG DISEASES AND RESPIRATORY TRACT
SE9801368D0 (en) * 1998-04-20 1998-04-20 Astra Ab New use

Also Published As

Publication number Publication date
PL355261A1 (en) 2004-04-05
NO20022057L (en) 2002-06-27
TR200201211T2 (en) 2002-08-21
NO20022057D0 (en) 2002-04-30
AP2002002496A0 (en) 2002-06-30
EP1225866A2 (en) 2002-07-31
HUP0203152A2 (en) 2003-01-28
CN1387404A (en) 2002-12-25
BG106748A (en) 2003-02-28
EA200200518A1 (en) 2002-10-31
BR0015270A (en) 2002-06-18
CA2388333A1 (en) 2001-05-10
ECSP003747A (en) 2002-05-23
TWI242431B (en) 2005-11-01
IL149367A0 (en) 2002-11-10
MXPA02004350A (en) 2002-11-07
AR029189A1 (en) 2003-06-18
JP2003513028A (en) 2003-04-08
CZ20021512A3 (en) 2003-04-16
DZ3225A1 (en) 2001-05-10
SK7592002A3 (en) 2002-11-06
HK1049107A1 (en) 2003-05-02
WO2001032127A3 (en) 2001-12-06
EP1225866A4 (en) 2004-04-21
AU1357501A (en) 2001-05-14
CO5261512A1 (en) 2003-03-31
KR20020057988A (en) 2002-07-12
WO2001032127A2 (en) 2001-05-10
OA12076A (en) 2006-05-04
HUP0203152A3 (en) 2004-06-28
ZA200203435B (en) 2003-06-25
MA26841A1 (en) 2004-12-20

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