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KR950018046A - Polypeptide - Google Patents

Polypeptide Download PDF

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Publication number
KR950018046A
KR950018046A KR1019930026545A KR930026545A KR950018046A KR 950018046 A KR950018046 A KR 950018046A KR 1019930026545 A KR1019930026545 A KR 1019930026545A KR 930026545 A KR930026545 A KR 930026545A KR 950018046 A KR950018046 A KR 950018046A
Authority
KR
South Korea
Prior art keywords
gly
gln
val
pro
polypeptide
Prior art date
Application number
KR1019930026545A
Other languages
Korean (ko)
Other versions
KR100290746B1 (en
Inventor
이복률
Original Assignee
김영길
주식회사 녹십자
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 김영길, 주식회사 녹십자 filed Critical 김영길
Priority to KR1019930026545A priority Critical patent/KR100290746B1/en
Publication of KR950018046A publication Critical patent/KR950018046A/en
Application granted granted Critical
Publication of KR100290746B1 publication Critical patent/KR100290746B1/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

본 발명은 항균성 폴리펩타이드에 관한 것이다. 더욱 상세하게는 그램음성균에 선택적으로 항균활성을 갖는 신규한 폴리펩타이드에 관한 것이다. 본 발명의 폴리펩타이드는 항균활성을 가지는 물질로서 의약 및 생활용품의 첨가제로 개발될 수있을 것이다.The present invention relates to antimicrobial polypeptides. More specifically, the present invention relates to a novel polypeptide having selectively antimicrobial activity against Gram-negative bacteria. The polypeptide of the present invention may be developed as an additive of medicine and household goods as a substance having antimicrobial activity.

Description

폴리펩타이드Polypeptide

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

제1도는 1차 C18역상 open cloumn으로 용출한 결과이다1 is the result of eluting with the first C 18 reversed phase open cloumn.

제2도는 2차 C18역상 open cloumn으로 용출한 결과이다2 is the result of eluting with the second C 18 reversed phase open cloumn.

Claims (3)

1 다음과 같은 아미노산 서열을 가지는 폴리펩타이드 Ser-Leu-Gln-Pro-Gly-1 Polypeptide Ser-Leu-Gln-Pro-Gly- having the following amino acid sequence Ala- Pro-Ser 10 20 -Phe-Pro-Gly-Ala-Pro-Gln-Gln-Asn-Gly-Gly-Trp-Ser-Val-Asn-Pro-Ser-Ala- Pro-Ser 10 20 -Phe-Pro-Gly-Ala-Pro-Gln-Gln-Asn-Gly-Gly-Trp-Ser-Val-Asn-Pro-Ser- Val-Gly- 30 40Arg-Asp-Glu-Arg-Gly-Asn-Gln-Arg-Thr-Asn-Val-Glu-Val-Gln-His-Lys-Gly-Val-Gly- 30 40 Arg-Asp-Glu-Arg-Gly-Asn-Gln-Arg-Thr-Asn-Val-Glu-Val-Gln-His-Lys-Gly- Gln- 50 60Asp-His-Asp-Phe-Asn-Ala-Gly-Trp-Gly-Lys-Val-Ile-Lys-Gly-Lys-Glu-Lys-Gly-Gln-50 60Asp-His-Asp-Phe-Asn-Ala-Gly-Trp-Gly-Lys-Val-Ile-Lys-Gly-Lys-Glu-Lys-Gly- 70Ser-Pro-Thr-Trp-His-Val-Gly-Gly-Ser-Phe-Arg70Ser-Pro-Thr-Trp-His-Val-Gly-Gly-Ser-Phe-Arg 제1항에 있어서, 갈색거저리(Tenebrio moliter)로부터 분리된 것을 특징으로하는 폴리펩타이드The polypeptide of claim 1, wherein the polypeptide is isolated from a brownish gourd (Tenebrio moliter). 제1항의 폴리펩타이드를 생물학적 활성성분으로 함유하는 항균제 조성물An antimicrobial composition comprising the polypeptide of claim 1 as a biologically active ingredient ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019930026545A 1993-12-06 1993-12-06 Polypeptide KR100290746B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019930026545A KR100290746B1 (en) 1993-12-06 1993-12-06 Polypeptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019930026545A KR100290746B1 (en) 1993-12-06 1993-12-06 Polypeptide

Publications (2)

Publication Number Publication Date
KR950018046A true KR950018046A (en) 1995-07-22
KR100290746B1 KR100290746B1 (en) 2001-06-01

Family

ID=37525833

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930026545A KR100290746B1 (en) 1993-12-06 1993-12-06 Polypeptide

Country Status (1)

Country Link
KR (1) KR100290746B1 (en)

Also Published As

Publication number Publication date
KR100290746B1 (en) 2001-06-01

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