KR840007022A - 글리콜산 백금 착체의 제조방법 - Google Patents
글리콜산 백금 착체의 제조방법 Download PDFInfo
- Publication number
- KR840007022A KR840007022A KR1019830005993A KR830005993A KR840007022A KR 840007022 A KR840007022 A KR 840007022A KR 1019830005993 A KR1019830005993 A KR 1019830005993A KR 830005993 A KR830005993 A KR 830005993A KR 840007022 A KR840007022 A KR 840007022A
- Authority
- KR
- South Korea
- Prior art keywords
- glycolic acid
- platinum complex
- vii
- acid platinum
- producing glycolic
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title claims 2
- FBULMICMSKHIAJ-UHFFFAOYSA-N 2-hydroxyacetic acid;platinum Chemical compound [Pt].OCC(O)=O FBULMICMSKHIAJ-UHFFFAOYSA-N 0.000 title 1
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims 2
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 claims 1
- CCZNQFWUNRMXSN-UHFFFAOYSA-N adamantane-1,2-diamine Chemical compound C1C(C2)CC3CC1C(N)C2(N)C3 CCZNQFWUNRMXSN-UHFFFAOYSA-N 0.000 claims 1
- 239000003957 anion exchange resin Substances 0.000 claims 1
- SSJXIUAHEKJCMH-UHFFFAOYSA-N cyclohexane-1,2-diamine Chemical compound NC1CCCCC1N SSJXIUAHEKJCMH-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/418—Preparation of metal complexes containing carboxylic acid moieties
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/06—Glycolic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (4)
- 하기 일반식(Ⅱ)의 화합물을 음이온 교환 수지로 처리하고 글리콜산으로 처리함을 특징으로 하는 하기 일반식(Ⅰ)의 화합물의 제조방법.
-
- 상기식중 Ｘ 및 Ｙ는 각각 직쇄 또는 측쇄의 알칼아민 이거나, Ｘ 및 Ｙ 는 함께 에틸렌디아민, 1,2-디아미노시클로헥산, 엑소-시스-2,3-디아미노비시클로 [2,2,1] 헵탄 또는 1,2-디아미노아다만탄을 형성한다.
- ※ 참고사항 : 최고출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57225272A JPS59112995A (ja) | 1982-12-21 | 1982-12-21 | 新規グリコ−ル酸白金錯体 |
| JP225272 | 1982-12-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR840007022A true KR840007022A (ko) | 1984-12-04 |
| KR890004350B1 KR890004350B1 (ko) | 1989-10-31 |
Family
ID=16826721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019830005993A KR890004350B1 (ko) | 1982-12-21 | 1983-12-19 | 글리콜산 백금 착체의 제조방법 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4560781A (ko) |
| EP (1) | EP0112591B1 (ko) |
| JP (1) | JPS59112995A (ko) |
| KR (1) | KR890004350B1 (ko) |
| CA (1) | CA1186307A (ko) |
| DE (1) | DE3364101D1 (ko) |
| GB (1) | GB2132201B (ko) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS617283A (ja) * | 1984-06-20 | 1986-01-13 | Shionogi & Co Ltd | 新規白金錯体および抗悪性腫瘍剤 |
| ATE63919T1 (de) * | 1984-06-27 | 1991-06-15 | Johnson Matthey Plc | Platinkoordinationsverbindungen. |
| US4680308A (en) * | 1985-12-26 | 1987-07-14 | Andrulis Research Corporation | Stable soluble 1,2-diaminocyclohexane platinum complexes |
| US5011959A (en) * | 1986-11-17 | 1991-04-30 | The Board Of Regents, The University Of Texas System | 1,2-diaminocyclohexane-platinum complexes with antitumor activity |
| US4904809A (en) * | 1987-09-25 | 1990-02-27 | Ss Pharmaceutical Co., Ltd. | Platinum complex |
| JPH01294683A (ja) * | 1988-02-04 | 1989-11-28 | Kanebo Ltd | 新規白金錯体および該化合物を有効成分とする抗腫瘍剤並びに該化合物製造用中間体 |
| US4931553A (en) * | 1988-05-11 | 1990-06-05 | Gill Devinder S | Platinum-polymer complexes and their use as antitumor agents |
| US5393909A (en) * | 1988-11-22 | 1995-02-28 | Board Of Regents, The University Of Texas System | Diamine platinum complexes as antitumor agents |
| JP2740919B2 (ja) * | 1989-03-30 | 1998-04-15 | 塩野義製薬株式会社 | 白金錯体およびこれらを有効成分として含有する抗腫瘍剤 |
| JPH08176176A (ja) * | 1994-12-26 | 1996-07-09 | Ss Pharmaceut Co Ltd | 白金錯体及びこれを含有する悪性腫瘍治療剤 |
| US7138520B2 (en) * | 2003-01-13 | 2006-11-21 | Massachusetts Institute Of Technology | Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same |
| CN104788498B (zh) * | 2015-03-23 | 2017-09-26 | 东南大学 | 一种以手性双环二胺为载体配体的铂(ii)配合物及其制备方法和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5829957B2 (ja) * | 1977-09-12 | 1983-06-25 | 喜徳 喜谷 | 新規な白金錯体 |
| US4225529A (en) * | 1977-10-19 | 1980-09-30 | Johnson, Matthey & Co., Limited | Compositions containing platinum |
| SE447385B (sv) * | 1977-10-19 | 1986-11-10 | Johnson Matthey Co Ltd | Cis-koordinationsforeningar av platina |
| US4203912A (en) * | 1977-10-19 | 1980-05-20 | Johnson, Matthey & Co., Limited | Compositions containing platinum |
| SE7903361L (sv) * | 1978-04-20 | 1979-10-21 | Johnson Matthey Co Ltd | Kompositioner innehallande platina |
| US4271085A (en) * | 1979-06-20 | 1981-06-02 | Engelhard Minerals & Chemicals Corporation | Cis-platinum (II) amine lactate complexes |
| GR75598B (ko) * | 1980-04-29 | 1984-08-01 | Sanofi Sa | |
| JPS56154493A (en) * | 1980-04-30 | 1981-11-30 | Shionogi & Co Ltd | Novel platinum complex |
| JPS5716895A (en) * | 1980-07-05 | 1982-01-28 | Otsuka Chem Co Ltd | Platinum 2 complex and antitumor agent containing the same as active principle |
| NL8101026A (nl) * | 1981-03-03 | 1982-10-01 | Tno | Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel. |
-
1982
- 1982-12-21 JP JP57225272A patent/JPS59112995A/ja active Granted
-
1983
- 1983-11-17 US US06/552,906 patent/US4560781A/en not_active Expired - Fee Related
- 1983-12-08 EP EP83201741A patent/EP0112591B1/en not_active Expired
- 1983-12-08 DE DE8383201741T patent/DE3364101D1/de not_active Expired
- 1983-12-19 GB GB08333715A patent/GB2132201B/en not_active Expired
- 1983-12-19 KR KR1019830005993A patent/KR890004350B1/ko not_active IP Right Cessation
- 1983-12-20 CA CA000443806A patent/CA1186307A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0112591B1 (en) | 1986-06-11 |
| KR890004350B1 (ko) | 1989-10-31 |
| GB2132201A (en) | 1984-07-04 |
| JPS59112995A (ja) | 1984-06-29 |
| US4560781A (en) | 1985-12-24 |
| JPH0251918B2 (ko) | 1990-11-08 |
| GB2132201B (en) | 1986-05-14 |
| CA1186307A (en) | 1985-04-30 |
| DE3364101D1 (en) | 1986-07-17 |
| GB8333715D0 (en) | 1984-01-25 |
| EP0112591A1 (en) | 1984-07-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR840004425A (ko) | N-알킬-노스코핀의 제조방법 | |
| KR860001110A (ko) | 항균제 ⅱ의 제법 | |
| KR840007022A (ko) | 글리콜산 백금 착체의 제조방법 | |
| KR850006386A (ko) | 아졸류의 제조방법 | |
| KR850003414A (ko) | (2-니트록시메틸-6-클로로피리딘)과 (β-사이클로덱스트린)의 교합화합물의 제조방법 | |
| KR840006492A (ko) | 플라티늄-디아민 착화물의 제조 방법 | |
| KR840005101A (ko) | 2-퀴놀린유도체의 제조방법 | |
| KR850001724A (ko) | 4-페닐-4-옥소-부텐-2-오인산유도체의 제조방법 | |
| KR830004292A (ko) | 벤조구아나민 유도체의 제조방법 | |
| KR830005191A (ko) | 푸란유도체의 제조방법 | |
| KR840006657A (ko) | 이소퀴놀린 화합물의 제조방법 | |
| KR850002979A (ko) | 1,2,3-트리티안화합물의 신규 제조방법 | |
| KR840006208A (ko) | 7-아닐리노이소퀴놀린-5,8-퀴논의 제조방법 | |
| KR840005114A (ko) | 아제티딘 술폰산의 제조방법 | |
| KR840003639A (ko) | 이속사졸로피리미딘 유도체의 제조방법 | |
| KR830001890A (ko) | 카바졸 유도체의 제조방법 | |
| KR880000411A (ko) | 벤조구아나민 유도체의 제법 | |
| KR860004074A (ko) | N-포스포노 메틸 글리신 염의 제조방법 | |
| KR840008335A (ko) | 살충제의 제조방법 | |
| KR860004021A (ko) | 에틸렌이민 유도체의 제조방법 | |
| KR850005839A (ko) | 에르고트 유도체의 제조방법 | |
| KR880006211A (ko) | 옥사졸 화합물의 제조방법 | |
| KR830006215A (ko) | 4-저급알킬-3-페녹시피리딘-1-옥사이드의 제조방법 | |
| KR850004098A (ko) | 부타놀 유도체의 제조방법 | |
| KR840001142A (ko) | 이미다졸 유도체의 제조방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| G160 | Decision to publish patent application | ||
| E701 | Decision to grant or registration of patent right | ||
| GRNT | Written decision to grant | ||
| FPAY | Annual fee payment |
Payment date: 19950517 Year of fee payment: 7 |
|
| LAPS | Lapse due to unpaid annual fee |