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JPS4949986A - - Google Patents

Info

Publication number
JPS4949986A
JPS4949986A JP48074353A JP7435373A JPS4949986A JP S4949986 A JPS4949986 A JP S4949986A JP 48074353 A JP48074353 A JP 48074353A JP 7435373 A JP7435373 A JP 7435373A JP S4949986 A JPS4949986 A JP S4949986A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP48074353A
Other versions
JPS5934716B2 (ja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH978872A external-priority patent/CH587268A5/de
Priority claimed from CH1872272A external-priority patent/CH605987A5/de
Priority claimed from CH265573A external-priority patent/CH605988A5/de
Application filed filed Critical
Publication of JPS4949986A publication Critical patent/JPS4949986A/ja
Publication of JPS5934716B2 publication Critical patent/JPS5934716B2/ja
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65613Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. cephalosporins and analogs
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP48074353A 1972-06-29 1973-06-29 θ−置換された7β−アミノ−3−セフエム−3−オ−ル−4−カルボン酸化合物の製法 Expired JPS5934716B2 (ja)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
CH978872A CH587268A5 (en) 1972-06-29 1972-06-29 Substd carboxylic acid derivs - broad spectrum antibiotics and inters
CH978872 1972-06-29
CH1219572 1972-08-17
CH1219572 1972-08-17
CH1872272A CH605987A5 (en) 1972-12-22 1972-12-22 Substd carboxylic acid derivs
CH1872272 1972-12-22
CH265573 1973-02-23
CH265573A CH605988A5 (en) 1973-02-23 1973-02-23 Substd 7-beta-amino ceph-3-em-3-ol 4-carboxylic acids

Publications (2)

Publication Number Publication Date
JPS4949986A true JPS4949986A (ja) 1974-05-15
JPS5934716B2 JPS5934716B2 (ja) 1984-08-24

Family

ID=27428472

Family Applications (3)

Application Number Title Priority Date Filing Date
JP48074354A Expired JPS5933598B2 (ja) 1972-06-29 1973-06-29 θ−置換された7β−アミノ−3−セフエム−3−オ−ル−4−カルボン酸化合物の製法
JP48074355A Expired JPS5933599B2 (ja) 1972-06-29 1973-06-29 O−置換された7β−アミノ−3−セフエム−3−オ−ル−4−カルボン酸化合物の製法
JP48074353A Expired JPS5934716B2 (ja) 1972-06-29 1973-06-29 θ−置換された7β−アミノ−3−セフエム−3−オ−ル−4−カルボン酸化合物の製法

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP48074354A Expired JPS5933598B2 (ja) 1972-06-29 1973-06-29 θ−置換された7β−アミノ−3−セフエム−3−オ−ル−4−カルボン酸化合物の製法
JP48074355A Expired JPS5933599B2 (ja) 1972-06-29 1973-06-29 O−置換された7β−アミノ−3−セフエム−3−オ−ル−4−カルボン酸化合物の製法

Country Status (26)

Country Link
US (2) US4405778A (ja)
JP (3) JPS5933598B2 (ja)
AR (6) AR206201A1 (ja)
AT (5) AT356810B (ja)
BE (1) BE801597A (ja)
BG (1) BG24954A3 (ja)
CA (1) CA1110230A (ja)
DD (3) DD107470A5 (ja)
DE (1) DE2331133C2 (ja)
DK (1) DK153324B (ja)
FI (3) FI59601C (ja)
FR (1) FR2190418B1 (ja)
GB (1) GB1435111A (ja)
HK (1) HK73778A (ja)
HU (3) HU168017B (ja)
IE (1) IE37767B1 (ja)
IL (1) IL42506A (ja)
LU (3) LU67891A1 (ja)
MY (1) MY7900008A (ja)
NL (3) NL7309136A (ja)
NO (3) NO145241C (ja)
PH (1) PH18567A (ja)
PL (1) PL91608B1 (ja)
RO (4) RO64226A (ja)
SE (5) SE417099B (ja)
YU (8) YU39909B (ja)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU36970B (en) * 1973-02-23 1984-08-31 Lilly Co Eli Process for obtaining 7-(amino)-acylamido-3-halocephalosporins
US4301278A (en) * 1974-02-26 1981-11-17 Ciba-Geigy Corporation Process for the manufacture of enol derivatives
AU498131B2 (en) * 1974-02-26 1979-02-15 Ciba-Geigy Ag Production of cephems by cyclization
US3928334A (en) * 1974-06-06 1975-12-23 Bristol Myers Co Process for the production of cefamandole
US4045435A (en) * 1974-10-09 1977-08-30 Eli Lilly And Company Preparation of cephalosporin ethers
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
US4147864A (en) * 1975-02-20 1979-04-03 Ciba-Geigy Corporation Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds
CH622802A5 (ja) * 1975-08-20 1981-04-30 Ciba Geigy Ag
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
US4604386A (en) * 1984-07-09 1986-08-05 Eli Lilly And Company 3-(alkynylalkyloxy) cephalosporins
GR861118B (en) 1985-04-30 1986-08-18 Lilly Co Eli 7-substituted bicyclic pyrazolidinones
EP0280240B1 (en) * 1987-02-27 1994-09-14 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, process for their preparation and antibacterial agents
JP2676763B2 (ja) * 1987-02-27 1997-11-17 萬有製薬株式会社 セファロスポリン誘導体
JPS63255800A (ja) * 1987-04-14 1988-10-24 礒井 誠二郎 警報装置
AU618029B2 (en) * 1987-11-02 1991-12-12 Imperial Chemical Industries Plc Polypeptide compounds
GB8813356D0 (en) * 1988-06-06 1988-07-13 Ici Plc Polypeptide compounds
DK0521827T3 (da) 1991-07-03 1996-11-11 Ciba Geigy Ag Farmakologisk virksomme hydrazinderivater og fremgangsmåde til deres fremstilling
GB9115203D0 (en) * 1991-07-15 1991-08-28 Biochemie Gmbh Improvements in or relating to beta lactam production
MXPA01009808A (es) * 1999-04-01 2002-04-24 Dsm Nv Aglomerados por cristalizacion.
US6627556B1 (en) 2002-04-24 2003-09-30 Lsi Logic Corporation Method of chemically altering a silicon surface and associated electrical devices
CN102268023B (zh) * 2011-08-15 2013-04-17 南京丰融化学技术有限公司 头孢类衍生物cxd的晶型
CN115160097B (zh) * 2022-07-22 2024-05-28 温州大学 一种硫代乙酸还原n-o键合成酰胺的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117903A1 (de) * 1970-04-14 1971-10-28 Beecham Group Ltd., Brentford, Middlesex (Grossbritannien) 4-Isopropyliden-3-oxocephame und ihre Säureadditionssalze, Verfahren zu ihrer Herstellung und ihre Verwendung als Ausgangsmaterialien für die Herstellung von antibakteriell wirksamen Verbindungen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1348985A (en) * 1970-06-16 1974-03-27 Merck & Co Inc Esters of cephalosporin compounds
IL37879A (en) * 1970-10-27 1974-12-31 Ciba Geigy Ag 3-unsubstituted cephalosporin derivatives,process for their manufacture and compositions containing them
US3704297A (en) * 1971-03-05 1972-11-28 American Home Prod 7 - (1,4 - cyclohexadienylacylamido)cephalosporanic acids and related compounds
US3741962A (en) * 1971-05-21 1973-06-26 Squibb & Sons Inc Alpha-thioureidocephalosporanic acid compounds
US3846417A (en) * 1972-06-23 1974-11-05 Squibb & Sons Inc 1,4-cyclohexadienyl imidazolidinyl cephalosporanic acids and derivatives thereof
US3917588A (en) * 1972-11-28 1975-11-04 Lilly Co Eli {60 -Aminoacyl cephalosporin ethers
US3917587A (en) * 1972-11-28 1975-11-04 Lilly Co Eli Cephalosporin ethers
US3907786A (en) * 1973-09-04 1975-09-23 Bristol Myers Co 7-{8 {60 -(2-aminomethyl-1,4-cyclohexadienyl)acetamido{9 -3-heterocyclic-thiomethyl-3-cephem-4-carboxylic acids and salts

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117903A1 (de) * 1970-04-14 1971-10-28 Beecham Group Ltd., Brentford, Middlesex (Grossbritannien) 4-Isopropyliden-3-oxocephame und ihre Säureadditionssalze, Verfahren zu ihrer Herstellung und ihre Verwendung als Ausgangsmaterialien für die Herstellung von antibakteriell wirksamen Verbindungen

Also Published As

Publication number Publication date
AU5738673A (en) 1975-01-09
NO145241C (no) 1982-02-10
SE417099B (sv) 1981-02-23
YU39910B (en) 1985-06-30
JPS5933598B2 (ja) 1984-08-16
DK153324B (da) 1988-07-04
YU179273A (en) 1982-06-30
SE417430B (sv) 1981-03-16
BG24954A3 (en) 1978-06-15
NO145240C (no) 1982-02-10
IE37767B1 (en) 1977-10-12
SE7308237L (ja) 1974-01-08
AR206201A1 (es) 1976-07-07
RO73345A (ro) 1982-09-09
IE37767L (en) 1973-12-29
AT329745B (de) 1976-05-25
NL7309136A (ja) 1974-01-02
HK73778A (en) 1978-12-22
JPS5934716B2 (ja) 1984-08-24
MY7900008A (en) 1979-12-31
SE7308233L (ja) 1973-12-31
AR211871A1 (es) 1978-03-31
NO145242B (no) 1981-11-02
NO145240B (no) 1981-11-02
RO63761A (fr) 1978-12-15
PH18567A (en) 1985-08-12
US4073902A (en) 1978-02-14
JPS5933599B2 (ja) 1984-08-16
FI60870C (fi) 1982-04-13
LU67887A1 (ja) 1975-04-11
BE801597A (fr) 1973-12-28
FI59601C (fi) 1981-09-10
FI59602C (fi) 1981-09-10
FI59601B (fi) 1981-05-29
PL91608B1 (en) 1977-03-31
SE7612053L (sv) 1976-10-29
ATA57675A (de) 1975-08-15
YU284280A (en) 1983-01-21
DD106187A5 (ja) 1974-06-05
ATA569573A (de) 1975-06-15
JPS4949987A (ja) 1974-05-15
RO64419A (fr) 1979-07-15
SE7308234L (sv) 1973-12-31
YU179573A (en) 1982-06-30
YU280780A (en) 1983-02-28
US4405778A (en) 1983-09-20
AR212576A1 (es) 1978-08-15
DD107470A5 (ja) 1974-08-05
DD106184A5 (ja) 1974-06-05
FR2190418A1 (ja) 1974-02-01
NL7309139A (ja) 1974-01-02
AT329762B (de) 1976-05-25
FI59602B (fi) 1981-05-29
NL7309137A (ja) 1974-01-02
ATA569673A (de) 1975-08-15
YU179373A (en) 1982-06-30
JPS4949988A (ja) 1974-05-15
FR2190418B1 (ja) 1977-07-15
AR211870A1 (es) 1978-03-31
DE2331133A1 (de) 1974-01-17
SE435289B (sv) 1984-09-17
IL42506A0 (en) 1973-08-29
AT356809B (de) 1980-05-27
RO64226A (fr) 1979-05-15
YU223881A (en) 1983-06-30
HU169032B (ja) 1976-09-28
YU223681A (en) 1983-06-30
LU67888A1 (ja) 1975-04-11
YU223781A (en) 1983-06-30
YU39911B (en) 1985-06-30
AR212028A1 (es) 1978-04-28
FI60870B (fi) 1981-12-31
IL42506A (en) 1976-09-30
LU67891A1 (ja) 1975-04-11
GB1435111A (en) 1976-05-12
SE417429B (sv) 1981-03-16
DE2331133C2 (de) 1984-04-12
YU39909B (en) 1985-06-30
ATA569473A (de) 1975-04-15
AT356810B (de) 1980-05-27
NO145242C (no) 1982-02-10
CA1110230A (en) 1981-10-06
HU168017B (ja) 1976-02-28
SE7308235L (ja) 1973-12-31
HU167726B (ja) 1975-12-25
NO145241B (no) 1981-11-02
AR212317A1 (es) 1978-06-30

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