IT8421343A0 - Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti. - Google Patents
Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti.Info
- Publication number
- IT8421343A0 IT8421343A0 IT8421343A IT2134384A IT8421343A0 IT 8421343 A0 IT8421343 A0 IT 8421343A0 IT 8421343 A IT8421343 A IT 8421343A IT 2134384 A IT2134384 A IT 2134384A IT 8421343 A0 IT8421343 A0 IT 8421343A0
- Authority
- IT
- Italy
- Prior art keywords
- acetals
- procedure
- preparation
- new compounds
- compounds obtained
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- JWMFYGXQPXQEEM-WZBAXQLOSA-N pregnane Chemical class C1CC2CCCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](CC)[C@@]1(C)CC2 JWMFYGXQPXQEEM-WZBAXQLOSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Saccharide Compounds (AREA)
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT21343/84A IT1196142B (it) | 1984-06-11 | 1984-06-11 | Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti |
FI852093A FI81809C (fi) | 1984-06-11 | 1985-05-24 | Foerfarande foer framstaellning av 16,17 -acetaler av pregnanderivat och foereningar erhaollna fraon dessa. |
ES543499A ES8705462A1 (es) | 1984-06-11 | 1985-05-24 | Un procedimiento para la preparacion de 16,17-acetales de derivados de pregnano |
EP85106522A EP0164636B1 (en) | 1984-06-11 | 1985-05-28 | A process for the preparation of 16,17 acetals of pregnane derivatives and compounds obtained therefrom |
AT85106522T ATE56725T1 (de) | 1984-06-11 | 1985-05-28 | Verfahren zur herstellung von 16,17-acetal von pregnanderivaten und die erhaltene verbindungen. |
DE8585106522T DE3579750D1 (de) | 1984-06-11 | 1985-05-28 | Verfahren zur herstellung von 16,17-acetal von pregnanderivaten und die erhaltene verbindungen. |
JP11762185A JPS6140299A (ja) | 1984-06-11 | 1985-05-30 | プレグナン誘導体の16,17―アセタール類の製造方法 |
US06/739,131 US4695625A (en) | 1984-06-11 | 1985-05-30 | Process for the preparation of 16,17 acetals of pregnane derivatives |
DK243085A DK163433C (da) | 1984-06-11 | 1985-05-30 | Fremgangsmaade til fremstilling af 16,17-acetaler af pregnanderivater |
CA000482945A CA1336513C (en) | 1984-06-11 | 1985-05-31 | Process for the preparation of 16, 17 acetals of pregnane derivatives and compounds obtained therefrom |
NO852327A NO164905C (no) | 1984-06-11 | 1985-06-10 | Fremgangsmaate for fremstilling av 16,17-acetal-pregnanderivater. |
US07/000,185 US4835145A (en) | 1984-06-11 | 1987-01-02 | 16,17 acetals of pregnane derivatives and pharmaceutical compositions containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT21343/84A IT1196142B (it) | 1984-06-11 | 1984-06-11 | Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti |
Publications (3)
Publication Number | Publication Date |
---|---|
IT8421343A0 true IT8421343A0 (it) | 1984-06-11 |
IT8421343A1 IT8421343A1 (it) | 1985-12-11 |
IT1196142B IT1196142B (it) | 1988-11-10 |
Family
ID=11180389
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT21343/84A IT1196142B (it) | 1984-06-11 | 1984-06-11 | Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti |
Country Status (11)
Country | Link |
---|---|
US (2) | US4695625A (it) |
EP (1) | EP0164636B1 (it) |
JP (1) | JPS6140299A (it) |
AT (1) | ATE56725T1 (it) |
CA (1) | CA1336513C (it) |
DE (1) | DE3579750D1 (it) |
DK (1) | DK163433C (it) |
ES (1) | ES8705462A1 (it) |
FI (1) | FI81809C (it) |
IT (1) | IT1196142B (it) |
NO (1) | NO164905C (it) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1196142B (it) * | 1984-06-11 | 1988-11-10 | Sicor Spa | Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti |
JPS6369953A (ja) * | 1986-09-11 | 1988-03-30 | Kobe Steel Ltd | 方向性の優れたアルミニウム合金の製造法 |
SE8604059D0 (sv) * | 1986-09-25 | 1986-09-25 | Astra Pharma Prod | A method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives |
JPS63156725A (ja) * | 1986-12-16 | 1988-06-29 | シコ−ル ソシエテ イタリア−ナ コルテイコステロイデイ エス・ピ−・エ− | 抗炎症剤 |
JPH01129688A (ja) * | 1987-11-16 | 1989-05-22 | Mitsubishi Electric Corp | 画像信号受信装置 |
SE8903219D0 (sv) * | 1989-10-02 | 1989-10-02 | Astra Ab | Process for the manufacture of budesonide |
GR1001529B (el) * | 1990-09-07 | 1994-03-31 | Elmuquimica Farm Sl | Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης. |
PL164294B1 (pl) * | 1990-12-20 | 1994-07-29 | Inst Farmaceutyczny | Sposób otrzymywania diastereoizomeru /22R/-16a , 17a-butylidenodioksy-11 ß 21-dihydroksy-1,4-pregnadien-3,20-dionu PL |
SE9100341D0 (sv) * | 1991-02-04 | 1991-02-04 | Astra Ab | Novel steroids |
US5888995A (en) * | 1991-02-04 | 1999-03-30 | Astra Aktiebolag | Steroid esters |
SE9100342D0 (sv) * | 1991-02-04 | 1991-02-04 | Astra Ab | Novel steroid esters |
SK281226B6 (sk) * | 1993-04-02 | 2001-01-18 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Prednizolónové deriváty, liečivá s ich obsahom a ich použitie |
GB9423919D0 (en) * | 1994-11-26 | 1995-01-11 | Rhone Poulenc Rorer Ltd | Chemical process |
DE19635498A1 (de) * | 1996-09-03 | 1998-03-26 | Byk Gulden Lomberg Chem Fab | Verfahren zur Epimerenanreicherung |
IT1291288B1 (it) * | 1997-04-30 | 1999-01-07 | Farmabios Srl | Processo per la preparazione di 16,17 acetali di derivati pregnanici con controllo della distribuzione epimerica al c-22. |
US20010031244A1 (en) * | 1997-06-13 | 2001-10-18 | Chiesi Farmaceutici S.P.A. | Pharmaceutical aerosol composition |
US6266556B1 (en) | 1998-04-27 | 2001-07-24 | Beth Israel Deaconess Medical Center, Inc. | Method and apparatus for recording an electroencephalogram during transcranial magnetic stimulation |
IT1302657B1 (it) * | 1998-10-13 | 2000-09-29 | Farmabios Srl | Processo stereoselettivo per la preparazione di budesonide nella formadi epimero 22-r. |
US6234167B1 (en) | 1998-10-14 | 2001-05-22 | Chrysalis Technologies, Incorporated | Aerosol generator and methods of making and using an aerosol generator |
DZ2947A1 (fr) * | 1998-11-25 | 2004-03-15 | Chiesi Farma Spa | Inhalateur à compteur de dose sous pression. |
US6315985B1 (en) * | 1999-06-18 | 2001-11-13 | 3M Innovative Properties Company | C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability |
IT1313553B1 (it) | 1999-07-23 | 2002-09-09 | Chiesi Farma Spa | Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione. |
IT1317720B1 (it) * | 2000-01-07 | 2003-07-15 | Chiesi Farma Spa | Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani. |
IT1317846B1 (it) | 2000-02-22 | 2003-07-15 | Chiesi Farma Spa | Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva. |
US6883516B2 (en) | 2000-04-27 | 2005-04-26 | Chrysalis Technologies Incorporated | Method for generating an aerosol with a predetermined and/or substantially monodispersed particle size distribution |
MY136453A (en) | 2000-04-27 | 2008-10-31 | Philip Morris Usa Inc | "improved method and apparatus for generating an aerosol" |
IT1318514B1 (it) * | 2000-05-12 | 2003-08-27 | Chiesi Farma Spa | Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari. |
DZ3358A1 (fr) | 2000-05-22 | 2001-11-29 | Chiesi Farma Spa | Formulations en solution pharmaceutiques pour inhalateurs-doseurs sous pression |
CA2430196C (en) * | 2000-11-10 | 2010-01-26 | Altana Pharma Ag | Process for the production of 16,17-[(cyclohexylmethylen)bis(oxy)]-11,21-dihydroxy-pregna-1,4-dien-3,20-dion or its 21-isobutyrat by transketalisation |
US6799572B2 (en) | 2000-12-22 | 2004-10-05 | Chrysalis Technologies Incorporated | Disposable aerosol generator system and methods for administering the aerosol |
US6701921B2 (en) | 2000-12-22 | 2004-03-09 | Chrysalis Technologies Incorporated | Aerosol generator having heater in multilayered composite and method of use thereof |
US7077130B2 (en) | 2000-12-22 | 2006-07-18 | Chrysalis Technologies Incorporated | Disposable inhaler system |
US6681998B2 (en) | 2000-12-22 | 2004-01-27 | Chrysalis Technologies Incorporated | Aerosol generator having inductive heater and method of use thereof |
US6501052B2 (en) | 2000-12-22 | 2002-12-31 | Chrysalis Technologies Incorporated | Aerosol generator having multiple heating zones and methods of use thereof |
US6491233B2 (en) | 2000-12-22 | 2002-12-10 | Chrysalis Technologies Incorporated | Vapor driven aerosol generator and method of use thereof |
TR200401980T4 (tr) * | 2001-07-02 | 2004-09-21 | Chiesi Farmaceutici S.P.A. | Aerosol olarak uygulama için en uygun hale getirilmiş tobramisin formülasyonu |
EP1275656A1 (en) * | 2001-07-11 | 2003-01-15 | Genchem Pharma Limited | Preparation of 9alpha-fluoro-11beta-hydroxypregnane 16,17-acetal derivatives |
CN101335322B (zh) * | 2001-09-03 | 2010-12-08 | 松下电器产业株式会社 | 荧光体层、半导体发光装置及半导体发光元件的制造方法 |
US6640050B2 (en) | 2001-09-21 | 2003-10-28 | Chrysalis Technologies Incorporated | Fluid vaporizing device having controlled temperature profile heater/capillary tube |
US6568390B2 (en) | 2001-09-21 | 2003-05-27 | Chrysalis Technologies Incorporated | Dual capillary fluid vaporizing device |
US6804458B2 (en) | 2001-12-06 | 2004-10-12 | Chrysalis Technologies Incorporated | Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate |
US6681769B2 (en) | 2001-12-06 | 2004-01-27 | Crysalis Technologies Incorporated | Aerosol generator having a multiple path heater arrangement and method of use thereof |
US6701922B2 (en) | 2001-12-20 | 2004-03-09 | Chrysalis Technologies Incorporated | Mouthpiece entrainment airflow control for aerosol generators |
LT3536344T (lt) * | 2002-03-01 | 2020-04-10 | Chiesi Farmaceutici S.P.A. | Ypatingai smulki formoterolio kompozicija |
US20040235811A1 (en) | 2002-10-08 | 2004-11-25 | Sepracor Inc. | Fatty acid modified forms of glucocorticoids |
US7367334B2 (en) | 2003-08-27 | 2008-05-06 | Philip Morris Usa Inc. | Fluid vaporizing device having controlled temperature profile heater/capillary tube |
EP1595531A1 (en) | 2004-05-13 | 2005-11-16 | CHIESI FARMACEUTICI S.p.A. | Stable pharmaceutical solution formulations for pressurized metered dose inhalers |
WO2007054974A2 (en) * | 2005-09-28 | 2007-05-18 | Arch Pharmalab Limited | A green chemistry process for the preparation of pregnadiene esters |
US20070135398A1 (en) * | 2005-11-02 | 2007-06-14 | Pierluigi Rossetto | Process for the preparation of ciclesonide |
US20070232578A1 (en) * | 2006-02-15 | 2007-10-04 | Pierluigi Rossetto | Crystalline forms of ciclesonide |
ITMI20080645A1 (it) | 2008-04-11 | 2009-10-12 | Ind Chimica Srl | Procedimento per la preparazione di budesonide |
CN101279997B (zh) * | 2008-05-29 | 2011-08-24 | 鲁南制药集团股份有限公司 | 布地奈德的一种制备方法 |
CN101863952B (zh) * | 2010-04-30 | 2013-04-17 | 湖北葛店人福药业有限责任公司 | 布地奈德的制备方法 |
CN102060906B (zh) * | 2010-12-23 | 2013-01-16 | 鲁南贝特制药有限公司 | 一种r布地奈德的制备方法 |
EP3250211B1 (en) | 2015-01-30 | 2021-12-22 | Coral Drugs Pvt. Ltd. | Novel process for preparation of glucocorticoid steroids |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE378109B (it) * | 1972-05-19 | 1975-08-18 | Bofors Ab | |
US3996359A (en) * | 1972-05-19 | 1976-12-07 | Ab Bofors | Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith |
SE378110B (it) * | 1972-05-19 | 1975-08-18 | Bofors Ab | |
SE8008524L (sv) * | 1980-12-04 | 1982-06-05 | Draco Ab | 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand |
IT1196142B (it) * | 1984-06-11 | 1988-11-10 | Sicor Spa | Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti |
DK176716B1 (da) * | 2007-09-03 | 2009-04-14 | Viking Life Saving Equip As | Redningsflådesystem |
-
1984
- 1984-06-11 IT IT21343/84A patent/IT1196142B/it active
-
1985
- 1985-05-24 ES ES543499A patent/ES8705462A1/es not_active Expired
- 1985-05-24 FI FI852093A patent/FI81809C/fi not_active IP Right Cessation
- 1985-05-28 AT AT85106522T patent/ATE56725T1/de not_active IP Right Cessation
- 1985-05-28 EP EP85106522A patent/EP0164636B1/en not_active Expired - Lifetime
- 1985-05-28 DE DE8585106522T patent/DE3579750D1/de not_active Expired - Lifetime
- 1985-05-30 DK DK243085A patent/DK163433C/da not_active IP Right Cessation
- 1985-05-30 US US06/739,131 patent/US4695625A/en not_active Expired - Lifetime
- 1985-05-30 JP JP11762185A patent/JPS6140299A/ja active Granted
- 1985-05-31 CA CA000482945A patent/CA1336513C/en not_active Expired - Lifetime
- 1985-06-10 NO NO852327A patent/NO164905C/no unknown
-
1987
- 1987-01-02 US US07/000,185 patent/US4835145A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0164636B1 (en) | 1990-09-19 |
ES8705462A1 (es) | 1987-05-01 |
DK243085D0 (da) | 1985-05-30 |
FI852093A0 (fi) | 1985-05-24 |
EP0164636A3 (en) | 1986-10-08 |
FI852093L (fi) | 1985-12-12 |
FI81809C (fi) | 1990-12-10 |
ATE56725T1 (de) | 1990-10-15 |
CA1336513C (en) | 1995-08-01 |
DK163433C (da) | 1992-07-27 |
US4695625A (en) | 1987-09-22 |
NO852327L (no) | 1985-12-12 |
DK243085A (da) | 1985-12-12 |
EP0164636A2 (en) | 1985-12-18 |
DK163433B (da) | 1992-03-02 |
NO164905B (no) | 1990-08-20 |
FI81809B (fi) | 1990-08-31 |
US4835145A (en) | 1989-05-30 |
IT8421343A1 (it) | 1985-12-11 |
DE3579750D1 (de) | 1990-10-25 |
NO164905C (no) | 1990-11-28 |
JPH0213680B2 (it) | 1990-04-04 |
ES543499A0 (es) | 1987-05-01 |
JPS6140299A (ja) | 1986-02-26 |
IT1196142B (it) | 1988-11-10 |
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Legal Events
Date | Code | Title | Description |
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TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970628 |