IN2014DN07983A - - Google Patents

Info

Publication number: IN2014DN07983A
Authority: IN; India
Prior art keywords: aceton; dimethylbenzene; bromo; preparation; discloses
Prior art date: 2012-05-08

Application number

Other languages

English (en)

Inventor

Doerwald Florencio Zaragoza

Anna Kulesza

Stephan Elzner

Robert Bujok

Zbigniew Wrobel

Krzysztof Wojciechowski

Original Assignee

Lonza Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-05-08

Filing date

2012-11-15

Publication date

2015-05-01

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47558543&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2014DN07983(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2012-10-22 Priority claimed from PCT/EP2012/070870 external-priority patent/WO2012172119A2/en

2012-11-15 Application filed by Lonza Ag filed Critical Lonza Ag

2015-05-01 Publication of IN2014DN07983A publication Critical patent/IN2014DN07983A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

IN7983DEN2014 2012-05-08 2012-11-15 IN2014DN07983A (el)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US201261644284P	2012-05-08	2012-05-08
EP12167134		2012-05-08
PCT/EP2012/070870 WO2012172119A2 (en)	2012-05-08	2012-10-22	Method for the preparation of medetomidine
EP12192612		2012-11-14
PCT/EP2012/072796 WO2013011155A2 (en)	2012-05-08	2012-11-15	Method for preparation of medetomidine

Publications (1)

Publication Number	Publication Date
IN2014DN07983A true IN2014DN07983A (el)	2015-05-01

Family

ID=47558543

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IN7983DEN2014 IN2014DN07983A (el)	2012-05-08	2012-11-15

Country Status (21)

Country	Link
US (1)	US9045433B2 (el)
EP (1)	EP2847173B1 (el)
JP (1)	JP5779297B2 (el)
KR (1)	KR101530506B1 (el)
CN (1)	CN104245679B (el)
AU (1)	AU2012285675B2 (el)
CA (1)	CA2866424A1 (el)
CL (1)	CL2014002905A1 (el)
CY (1)	CY1117490T1 (el)
DK (1)	DK2847173T3 (el)
EA (1)	EA025950B1 (el)
ES (1)	ES2563816T3 (el)
HK (1)	HK1201532A1 (el)
HR (1)	HRP20160215T1 (el)
HU (1)	HUE027384T2 (el)
IN (1)	IN2014DN07983A (el)
MY (1)	MY166058A (el)
PL (1)	PL2847173T3 (el)
SG (1)	SG11201405606RA (el)
TW (1)	TWI529164B (el)
WO (1)	WO2013011155A2 (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5777840B2 (ja)	2012-05-08	2015-09-09	ロンザ・リミテッド	２−（２，３−ジメチルフェニル）−１−プロパナールを調製するための方法
SG11201405606RA (en) *	2012-05-08	2014-11-27	Lonza Ag	Method for preparation of medetomidine
JP5777841B2 (ja)	2012-06-28	2015-09-09	ロンザ・リミテッド	クロロアセトンを用いてメデトミジンを調製するための方法
MY165118A (en) *	2012-06-28	2018-02-28	Lonza Ag	Method for preparation of 2-(2,3-dimethylphenyl)-1-propanal with chloroacetone
CN106518812A (zh) *	2016-10-25	2017-03-22	湖南大学	一种美托咪定及其中间体的制备方法
CN111548308A (zh) *	2020-03-18	2020-08-18	遂成药业股份有限公司	一种盐酸右美托咪定的合成工艺
KR102341174B1 (ko) *	2021-09-13	2021-12-20	주식회사 세라수	양이온교환 섬유를 사용한 테레프탈릴리덴 디캠퍼 설폰산염의 산성화 방법
CN114671811A (zh) *	2022-04-14	2022-06-28	南京正科医药股份有限公司	一种右美托咪定拆分副产物的外消旋化回收方法

Family Cites Families (21)

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BE790604A (fr)	1971-10-28	1973-04-26	Sandoz Sa	Nouveaux aminoalcanols, leur preparation et leur application comme medicaments
JPS51100041A (en)	1975-02-26	1976-09-03	Kanebo Ltd	22 * 44 isobuchirufueniru * puropionsanno seizoho
JPS51100042A (en)	1975-02-26	1976-09-03	Kanebo Ltd	22 * 44 isobuchirufueniru * puropionsanno seizoho
GB2092569B (en)	1981-02-05	1984-09-19	Farmos Oy	Substituted imidazole derivatives and their preparation and use
GB2101114B (en)	1981-07-10	1985-05-22	Farmos Group Ltd	Substituted imidazole derivatives and their preparation and use
EP0153692B1 (en)	1984-02-24	1992-07-29	Sagami Chemical Research Center	Method for isomerization a glycidate derivative
JPS62103037A (ja) *	1985-10-29	1987-05-13	Hamari Yakuhin Kogyo Kk	２−（４−イソブチルフエニル）−プロピオンアルデヒドの製造法
DE19714042A1 (de)	1997-04-05	1998-10-08	Henkel Kgaa	Verfahren zur Herstellung aromatischer Aldehyde
SE513474C2 (sv)	1999-01-25	2000-09-18	Hans Elwing Instutionen Foer C	Metod för att förhindra kräftdjurs, särskilt havstulpaners, etablering på fasta ytor med hjälp av en substans som stör nervsignaler, varvid substansen är medetomidin, dvs (+)-4-/1- (2,3-dimetylfenyl)-etyl/-IH-imidazol
EP1918282A1 (en)	2006-11-06	2008-05-07	"Joint Stock Company Grindeks"	Method for preparing medetomidine and its salts
GB2453982B (en) *	2007-10-24	2009-09-16	Norbrook Lab Ltd	Chemical process for the preparation of Medetomidine
US7902247B2 (en)	2008-01-09	2011-03-08	Allergan, Inc.	Substituted-aryl-2-phenylethyl-1H-imidazole compounds as subtype selective modulators of alpha 2B and/or alpha 2C adrenergic receptors
CN102753532B (zh) *	2009-12-09	2015-05-13	I-技术有限公司	美托咪定的制备方法
JP5777840B2 (ja) *	2012-05-08	2015-09-09	ロンザ・リミテッド	２−（２，３−ジメチルフェニル）−１−プロパナールを調製するための方法
WO2012172120A2 (en) *	2012-05-08	2012-12-20	Lonza Ltd	2-(2,3-dimethylphenyl)-1-propanal and its use as perfume
SG11201405606RA (en) *	2012-05-08	2014-11-27	Lonza Ag	Method for preparation of medetomidine
WO2012172119A2 (en) *	2012-05-08	2012-12-20	Lonza Ltd	Method for the preparation of medetomidine
WO2012172122A2 (en) *	2012-06-28	2012-12-20	Lonza Ltd	Method for the preparation of 2-(2,3-dimethylphenyl)-1-propanal
WO2012172121A1 (en) *	2012-06-28	2012-12-20	Lonza Ltd	Method for the preparation of medetomidine with chloroacetone
JP5777841B2 (ja) *	2012-06-28	2015-09-09	ロンザ・リミテッド	クロロアセトンを用いてメデトミジンを調製するための方法
MY165118A (en) *	2012-06-28	2018-02-28	Lonza Ag	Method for preparation of 2-(2,3-dimethylphenyl)-1-propanal with chloroacetone

2012
- 2012-11-15 SG SG11201405606RA patent/SG11201405606RA/en unknown
- 2012-11-15 JP JP2015510660A patent/JP5779297B2/ja not_active Expired - Fee Related
- 2012-11-15 ES ES12784296.1T patent/ES2563816T3/es active Active
- 2012-11-15 DK DK12784296.1T patent/DK2847173T3/en active
- 2012-11-15 WO PCT/EP2012/072796 patent/WO2013011155A2/en active Application Filing
- 2012-11-15 MY MYPI2014002563A patent/MY166058A/en unknown
- 2012-11-15 EA EA201400940A patent/EA025950B1/ru not_active IP Right Cessation
- 2012-11-15 IN IN7983DEN2014 patent/IN2014DN07983A/en unknown
- 2012-11-15 EP EP12784296.1A patent/EP2847173B1/en not_active Not-in-force
- 2012-11-15 CA CA2866424A patent/CA2866424A1/en not_active Abandoned
- 2012-11-15 PL PL12784296T patent/PL2847173T3/pl unknown
- 2012-11-15 US US14/386,054 patent/US9045433B2/en not_active Expired - Fee Related
- 2012-11-15 AU AU2012285675A patent/AU2012285675B2/en not_active Ceased
- 2012-11-15 CN CN201280072266.6A patent/CN104245679B/zh not_active Expired - Fee Related
- 2012-11-15 KR KR1020147029915A patent/KR101530506B1/ko active IP Right Grant
- 2012-11-15 HU HUE12784296A patent/HUE027384T2/en unknown
2013
- 2013-05-06 TW TW102116032A patent/TWI529164B/zh not_active IP Right Cessation
2014
- 2014-10-27 CL CL2014002905A patent/CL2014002905A1/es unknown
2015
- 2015-03-03 HK HK15102124.8A patent/HK1201532A1/zh not_active IP Right Cessation
2016
- 2016-03-01 HR HRP20160215T patent/HRP20160215T1/hr unknown
- 2016-03-17 CY CY20161100228T patent/CY1117490T1/el unknown

Also Published As

Publication number	Publication date
HK1201532A1 (zh)	2015-09-04
TW201408648A (zh)	2014-03-01
JP5779297B2 (ja)	2015-09-16
WO2013011155A2 (en)	2013-01-24
EP2847173A2 (en)	2015-03-18
US20150057453A1 (en)	2015-02-26
CA2866424A1 (en)	2013-01-24
HRP20160215T1 (hr)	2016-03-25
CN104245679A (zh)	2014-12-24
CL2014002905A1 (es)	2014-12-12
KR101530506B1 (ko)	2015-06-19
CN104245679B (zh)	2016-03-02
PL2847173T3 (pl)	2016-06-30
DK2847173T3 (en)	2016-04-04
JP2015517472A (ja)	2015-06-22
EP2847173B1 (en)	2015-12-30
AU2012285675B2 (en)	2016-03-03
KR20140136523A (ko)	2014-11-28
NZ700640A (en)	2016-03-31
HUE027384T2 (en)	2016-10-28
EA025950B1 (ru)	2017-02-28
WO2013011155A3 (en)	2013-04-04
US9045433B2 (en)	2015-06-02
AU2012285675A1 (en)	2014-10-16
SG11201405606RA (en)	2014-11-27
ES2563816T3 (es)	2016-03-16
TWI529164B (zh)	2016-04-11
MY166058A (en)	2018-05-22
CY1117490T1 (el)	2017-04-26
EA201400940A1 (ru)	2015-01-30

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