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IL75913A - Phenyl-nonatetraenoic acid derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Phenyl-nonatetraenoic acid derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL75913A
IL75913A IL75913A IL7591385A IL75913A IL 75913 A IL75913 A IL 75913A IL 75913 A IL75913 A IL 75913A IL 7591385 A IL7591385 A IL 7591385A IL 75913 A IL75913 A IL 75913A
Authority
IL
Israel
Prior art keywords
phenyl
preparation
pharmaceutical compositions
compositions containing
acid derivatives
Prior art date
Application number
IL75913A
Other languages
English (en)
Other versions
IL75913A0 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL75913A0 publication Critical patent/IL75913A0/xx
Publication of IL75913A publication Critical patent/IL75913A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/42Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734Ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • C07C57/48Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid having unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5456Arylalkanephosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL75913A 1984-07-27 1985-07-25 Phenyl-nonatetraenoic acid derivatives,their preparation and pharmaceutical compositions containing them IL75913A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63510084A 1984-07-27 1984-07-27

Publications (2)

Publication Number Publication Date
IL75913A0 IL75913A0 (en) 1985-12-31
IL75913A true IL75913A (en) 1989-06-30

Family

ID=24546455

Family Applications (1)

Application Number Title Priority Date Filing Date
IL75913A IL75913A (en) 1984-07-27 1985-07-25 Phenyl-nonatetraenoic acid derivatives,their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
EP (1) EP0169571B1 (fi)
JP (1) JPH06716B2 (fi)
KR (1) KR930000112B1 (fi)
AR (1) AR242023A1 (fi)
AT (1) ATE32882T1 (fi)
AU (2) AU589130B2 (fi)
CA (1) CA1277332C (fi)
CS (1) CS256392B2 (fi)
DE (1) DE3561808D1 (fi)
DK (1) DK173287B1 (fi)
ES (2) ES8703825A1 (fi)
FI (1) FI84345C (fi)
GR (1) GR851841B (fi)
HU (1) HU195480B (fi)
IE (1) IE58735B1 (fi)
IL (1) IL75913A (fi)
MC (1) MC1692A1 (fi)
NO (1) NO161064C (fi)
NZ (1) NZ212868A (fi)
PH (1) PH21556A (fi)
PT (1) PT80876B (fi)
ZA (1) ZA854828B (fi)
ZW (1) ZW12185A1 (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ232865A (en) * 1989-03-21 1992-07-28 Hoffmann La Roche A mixed-micelle solution comprising a micelle former and an immunomodulator
DE4036779A1 (de) * 1990-11-17 1992-05-21 Basf Ag Verwendung von arylpolyencarbonsaeuren und ihren derivaten als lichtschutzmittel in kosmetischen zubereitungen
US7655699B1 (en) 1992-04-22 2010-02-02 Eisai Inc. Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
US5369126A (en) * 1993-01-06 1994-11-29 Hoffmann-La Roche Inc. Nonatetraenoic acid derivative for use in treating acne
CA2129773C (en) * 1993-09-02 2007-05-01 Michael Klaus Aromatic carboxylic acid derivatives
US7115728B1 (en) 1995-01-30 2006-10-03 Ligand Pharmaceutical Incorporated Human peroxisome proliferator activated receptor γ
US7098025B1 (en) 1997-07-25 2006-08-29 Ligand Pharmaceuticals Incorporated Human peroxisome proliferator activated receptor gamma (pparγ) gene regulatory sequences and uses therefor
WO2006046595A1 (ja) * 2004-10-28 2006-05-04 Sankyo Company, Limited 光学活性4,4-二置換オキサゾリジン誘導体とその製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3334125A (en) * 1964-02-26 1967-08-01 Velsicol Chemical Corp Esters of 3-6-dichloro-2-methoxy-benzyl alcohol
CH585166A5 (fi) * 1973-03-30 1977-02-28 Hoffmann La Roche
CH605562A5 (fi) * 1974-09-26 1978-09-29 Hoffmann La Roche
DE2933985A1 (de) * 1979-08-22 1981-04-09 Bayer Ag, 5090 Leverkusen Neue 4-fluor-3-phenoxy-benzyl-ether und verfahren zu deren herstellung sowie neue zwischenprodukte hierfuer und verfahren zu deren herstellung

Also Published As

Publication number Publication date
HU195480B (en) 1988-05-30
CA1277332C (en) 1990-12-04
NO852980L (no) 1986-01-28
FI852899A0 (fi) 1985-07-25
FI84345C (fi) 1991-11-25
ZA854828B (en) 1986-03-26
GR851841B (fi) 1985-12-02
EP0169571A1 (de) 1986-01-29
ZW12185A1 (en) 1986-02-26
HUT38306A (en) 1986-05-28
CS550285A2 (en) 1987-08-13
AU4260889A (en) 1990-01-25
AU619901B2 (en) 1992-02-06
ES545565A0 (es) 1987-03-01
IE58735B1 (en) 1993-11-03
JPH06716B2 (ja) 1994-01-05
IE851881L (en) 1986-01-27
DK173287B1 (da) 2000-06-13
IL75913A0 (en) 1985-12-31
KR860001044A (ko) 1986-02-22
AU589130B2 (en) 1989-10-05
EP0169571B1 (de) 1988-03-09
DK340485D0 (da) 1985-07-25
DE3561808D1 (en) 1988-04-14
CS256392B2 (en) 1988-04-15
ATE32882T1 (de) 1988-03-15
KR930000112B1 (ko) 1993-01-09
MC1692A1 (fr) 1986-07-18
PH21556A (en) 1987-12-11
FI84345B (fi) 1991-08-15
AU4557585A (en) 1986-01-30
ES552061A0 (es) 1987-05-01
JPS6143135A (ja) 1986-03-01
PT80876A (en) 1986-07-17
ES8705355A1 (es) 1987-05-01
FI852899L (fi) 1986-01-28
NO161064B (no) 1989-03-20
DK340485A (da) 1986-01-28
AR242023A1 (es) 1993-02-26
ES8703825A1 (es) 1987-03-01
NZ212868A (en) 1989-05-29
NO161064C (no) 1989-06-28
PT80876B (pt) 1987-11-30

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Legal Events

Date Code Title Description
KB Patent renewed
RH1 Patent not in force