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FI852899L - Foerfarande foer framstaellning av fenylsubstituerade 2,4,6,8-nonatetraensyror. - Google Patents

Foerfarande foer framstaellning av fenylsubstituerade 2,4,6,8-nonatetraensyror.

Info

Publication number
FI852899L
FI852899L FI852899A FI852899A FI852899L FI 852899 L FI852899 L FI 852899L FI 852899 A FI852899 A FI 852899A FI 852899 A FI852899 A FI 852899A FI 852899 L FI852899 L FI 852899L
Authority
FI
Finland
Prior art keywords
nonatetraensyror
fenylsubstituerade
foerfarande foer
foer framstaellning
framstaellning
Prior art date
Application number
FI852899A
Other languages
English (en)
Other versions
FI84345B (fi
FI852899A0 (fi
FI84345C (fi
Inventor
Edward Roy Aig
John William Coffey
Allen John Lovey
Michael Rosenberger
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI852899A0 publication Critical patent/FI852899A0/fi
Publication of FI852899L publication Critical patent/FI852899L/fi
Publication of FI84345B publication Critical patent/FI84345B/fi
Application granted granted Critical
Publication of FI84345C publication Critical patent/FI84345C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/42Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734Ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • C07C57/48Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid having unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5456Arylalkanephosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI852899A 1984-07-27 1985-07-25 Foerfarande foer framstaellning av anti-inflammatoriska och immunosuppressiva fenylnonatetraensyraderivat. FI84345C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63510084A 1984-07-27 1984-07-27
US63510084 1984-07-27

Publications (4)

Publication Number Publication Date
FI852899A0 FI852899A0 (fi) 1985-07-25
FI852899L true FI852899L (fi) 1986-01-28
FI84345B FI84345B (fi) 1991-08-15
FI84345C FI84345C (fi) 1991-11-25

Family

ID=24546455

Family Applications (1)

Application Number Title Priority Date Filing Date
FI852899A FI84345C (fi) 1984-07-27 1985-07-25 Foerfarande foer framstaellning av anti-inflammatoriska och immunosuppressiva fenylnonatetraensyraderivat.

Country Status (23)

Country Link
EP (1) EP0169571B1 (fi)
JP (1) JPH06716B2 (fi)
KR (1) KR930000112B1 (fi)
AR (1) AR242023A1 (fi)
AT (1) ATE32882T1 (fi)
AU (2) AU589130B2 (fi)
CA (1) CA1277332C (fi)
CS (1) CS256392B2 (fi)
DE (1) DE3561808D1 (fi)
DK (1) DK173287B1 (fi)
ES (2) ES8703825A1 (fi)
FI (1) FI84345C (fi)
GR (1) GR851841B (fi)
HU (1) HU195480B (fi)
IE (1) IE58735B1 (fi)
IL (1) IL75913A (fi)
MC (1) MC1692A1 (fi)
NO (1) NO161064C (fi)
NZ (1) NZ212868A (fi)
PH (1) PH21556A (fi)
PT (1) PT80876B (fi)
ZA (1) ZA854828B (fi)
ZW (1) ZW12185A1 (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ232865A (en) * 1989-03-21 1992-07-28 Hoffmann La Roche A mixed-micelle solution comprising a micelle former and an immunomodulator
DE4036779A1 (de) * 1990-11-17 1992-05-21 Basf Ag Verwendung von arylpolyencarbonsaeuren und ihren derivaten als lichtschutzmittel in kosmetischen zubereitungen
US7655699B1 (en) 1992-04-22 2010-02-02 Eisai Inc. Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
US5369126A (en) * 1993-01-06 1994-11-29 Hoffmann-La Roche Inc. Nonatetraenoic acid derivative for use in treating acne
CA2129773C (en) 1993-09-02 2007-05-01 Michael Klaus Aromatic carboxylic acid derivatives
US7115728B1 (en) 1995-01-30 2006-10-03 Ligand Pharmaceutical Incorporated Human peroxisome proliferator activated receptor γ
AU8588798A (en) 1997-07-25 1999-02-16 Institut Pasteur Human peroxisome proliferator activated receptor gamma (ppargamma) gene re gulatory sequences and uses therefor
KR101285483B1 (ko) * 2004-10-28 2013-07-12 상꾜 가부시키가이샤 광학 활성 4,4-2치환 옥사졸리딘 유도체와 그 제조 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3334125A (en) * 1964-02-26 1967-08-01 Velsicol Chemical Corp Esters of 3-6-dichloro-2-methoxy-benzyl alcohol
CH585166A5 (fi) * 1973-03-30 1977-02-28 Hoffmann La Roche
CH605562A5 (fi) * 1974-09-26 1978-09-29 Hoffmann La Roche
DE2933985A1 (de) * 1979-08-22 1981-04-09 Bayer Ag, 5090 Leverkusen Neue 4-fluor-3-phenoxy-benzyl-ether und verfahren zu deren herstellung sowie neue zwischenprodukte hierfuer und verfahren zu deren herstellung

Also Published As

Publication number Publication date
ZW12185A1 (en) 1986-02-26
EP0169571A1 (de) 1986-01-29
IE851881L (en) 1986-01-27
MC1692A1 (fr) 1986-07-18
PH21556A (en) 1987-12-11
AR242023A1 (es) 1993-02-26
AU4557585A (en) 1986-01-30
AU589130B2 (en) 1989-10-05
GR851841B (fi) 1985-12-02
FI84345B (fi) 1991-08-15
CS256392B2 (en) 1988-04-15
IL75913A0 (en) 1985-12-31
DK173287B1 (da) 2000-06-13
CS550285A2 (en) 1987-08-13
JPH06716B2 (ja) 1994-01-05
EP0169571B1 (de) 1988-03-09
ES545565A0 (es) 1987-03-01
IL75913A (en) 1989-06-30
FI852899A0 (fi) 1985-07-25
ES8705355A1 (es) 1987-05-01
ZA854828B (en) 1986-03-26
NO161064C (no) 1989-06-28
AU619901B2 (en) 1992-02-06
JPS6143135A (ja) 1986-03-01
KR860001044A (ko) 1986-02-22
NO161064B (no) 1989-03-20
IE58735B1 (en) 1993-11-03
ES8703825A1 (es) 1987-03-01
DK340485D0 (da) 1985-07-25
FI84345C (fi) 1991-11-25
HUT38306A (en) 1986-05-28
NO852980L (no) 1986-01-28
AU4260889A (en) 1990-01-25
HU195480B (en) 1988-05-30
ATE32882T1 (de) 1988-03-15
NZ212868A (en) 1989-05-29
PT80876B (pt) 1987-11-30
CA1277332C (en) 1990-12-04
KR930000112B1 (ko) 1993-01-09
PT80876A (en) 1986-07-17
DK340485A (da) 1986-01-28
ES552061A0 (es) 1987-05-01
DE3561808D1 (en) 1988-04-14

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE AG