IL159649A0 - Viral polymerase inhibitors - Google Patents

Viral polymerase inhibitors

Info

Publication number: IL159649A0
Authority: IL; Israel
Prior art keywords: polymerase inhibitors; viral polymerase; viral; inhibitors; polymerase
Prior art date: 2001-07-25

Application number

IL15964902A

Other languages

English (en)

Original Assignee

Boehringer Ingelheim Ca Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-25

Filing date

2002-07-18

Publication date

2004-06-01

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26975871&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL159649(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-07-18 Application filed by Boehringer Ingelheim Ca Ltd filed Critical Boehringer Ingelheim Ca Ltd

2004-06-01 Publication of IL159649A0 publication Critical patent/IL159649A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Virology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Saccharide Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

IL15964902A 2001-07-25 2002-07-18 Viral polymerase inhibitors IL159649A0 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US30767401P	2001-07-25	2001-07-25
US33806101P	2001-12-07	2001-12-07
PCT/CA2002/001128 WO2003010141A2 (en)	2001-07-25	2002-07-18	Hepatitis c virus polymerase inhibitors with a heterobicyclic structure

Publications (1)

Publication Number	Publication Date
IL159649A0 true IL159649A0 (en)	2004-06-01

Family

ID=26975871

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
IL15964902A IL159649A0 (en)	2001-07-25	2002-07-18	Viral polymerase inhibitors
IL15954502A IL159545A0 (en)	2001-07-25	2002-07-18	Viral polymerase inhibitors
IL159545A IL159545A (en)	2001-07-25	2003-12-24	Heterocytic carboxylic acid - 6 carboxylic acid history
IL222761A IL222761A0 (en)	2001-07-25	2012-10-30	Viral polymerase inhibitors

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
IL15954502A IL159545A0 (en)	2001-07-25	2002-07-18	Viral polymerase inhibitors
IL159545A IL159545A (en)	2001-07-25	2003-12-24	Heterocytic carboxylic acid - 6 carboxylic acid history
IL222761A IL222761A0 (en)	2001-07-25	2012-10-30	Viral polymerase inhibitors

Country Status (34)

Country	Link
US (5)	US7141574B2 (de)
EP (5)	EP2335700A1 (de)
JP (4)	JP4398725B2 (de)
KR (3)	KR101031183B1 (de)
CN (3)	CN102424680A (de)
AR (2)	AR037495A1 (de)
AT (2)	ATE382605T1 (de)
AU (2)	AU2002355150B2 (de)
BR (2)	BR0211477A (de)
CA (2)	CA2450033C (de)
CO (2)	CO5650161A2 (de)
CY (2)	CY1107355T1 (de)
DE (2)	DE60224400T2 (de)
DK (2)	DK1414797T3 (de)
EA (2)	EA007715B1 (de)
ES (2)	ES2299588T3 (de)
HK (2)	HK1069991A1 (de)
HR (3)	HRP20040072B1 (de)
HU (2)	HUP0401784A3 (de)
IL (4)	IL159649A0 (de)
ME (2)	MEP62108A (de)
MX (2)	MXPA04000731A (de)
MY (1)	MY151080A (de)
NO (2)	NO327055B1 (de)
NZ (2)	NZ531267A (de)
PE (1)	PE20030305A1 (de)
PL (2)	PL368357A1 (de)
PT (2)	PT1414441E (de)
RS (3)	RS20090517A (de)
SG (1)	SG176999A1 (de)
SI (2)	SI1414441T1 (de)
UA (1)	UA84256C2 (de)
UY (1)	UY27397A1 (de)
WO (2)	WO2003010141A2 (de)

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Also Published As

Publication number	Publication date
RS7004A (en)	2006-12-15
DE60224400T2 (de)	2008-12-18
SG176999A1 (en)	2012-01-30
EP1891951A1 (de)	2008-02-27
HRP20040072B1 (en)	2012-01-31
NO20040282L (no)	2004-01-21
KR20040023675A (ko)	2004-03-18
WO2003010141A2 (en)	2003-02-06
EA200400114A1 (ru)	2004-08-26
PL368357A1 (en)	2005-03-21
UA84256C2 (en)	2008-10-10
DK1414441T3 (da)	2008-05-13
RS51083B (sr)	2010-10-31
DE60224401T2 (de)	2009-01-02
DK1414797T3 (da)	2008-05-13
US20030176433A1 (en)	2003-09-18
JP4398241B2 (ja)	2010-01-13
KR101031183B1 (ko)	2011-04-26
RS20090517A (en)	2010-05-07
HUP0402065A3 (en)	2013-06-28
CA2450033C (en)	2009-07-07
EP1414441A2 (de)	2004-05-06
US7893084B2 (en)	2011-02-22
WO2003010140A3 (en)	2003-07-10
UY27397A1 (es)	2003-02-28
KR100949446B1 (ko)	2010-03-29
JP2009275037A (ja)	2009-11-26
HRP20090668A2 (hr)	2010-07-31
HK1073786A1 (en)	2005-10-21
MXPA04000729A (es)	2004-06-25
IL159545A0 (en)	2004-06-01
AR073106A2 (es)	2010-10-13
ATE382348T1 (de)	2008-01-15
MXPA04000731A (es)	2004-06-25
NZ531267A (en)	2006-02-24
WO2003010141A3 (en)	2003-05-30
NZ531229A (en)	2006-03-31
AU2002313410B2 (en)	2008-09-11
EA007715B1 (ru)	2006-12-29
CA2449180A1 (en)	2003-02-06
KR100950868B1 (ko)	2010-04-06
NO333121B1 (no)	2013-03-04
PT1414441E (pt)	2008-03-07
CN1558759A (zh)	2004-12-29
SI1414441T1 (sl)	2008-06-30
CO5650162A2 (es)	2006-06-30
US7576079B2 (en)	2009-08-18
JP2004537564A (ja)	2004-12-16
CN100443469C (zh)	2008-12-17
BR0211477A (pt)	2004-08-17
HK1069991A1 (en)	2005-06-10
CO5650161A2 (es)	2006-06-30
PL372125A1 (en)	2005-07-11
US7803944B2 (en)	2010-09-28
ATE382605T1 (de)	2008-01-15
MEP62108A (en)	2011-05-10
JP4398725B2 (ja)	2010-01-13
EP1414797B9 (de)	2009-04-15
KR20100002296A (ko)	2010-01-06
EP1891950A1 (de)	2008-02-27
HUP0402065A2 (hu)	2005-02-28
HRP20040073B1 (en)	2012-02-29
AU2002355150B2 (en)	2008-08-07
CA2449180C (en)	2010-04-27
US20040024190A1 (en)	2004-02-05
ES2299588T3 (es)	2008-06-01
JP2009120616A (ja)	2009-06-04
NO327055B1 (no)	2009-04-14
EP1414797A2 (de)	2004-05-06
YU6904A (sh)	2006-08-17
IL159545A (en)	2013-11-28
JP2005504030A (ja)	2005-02-10
MY151080A (en)	2014-04-15
HUP0401784A2 (hu)	2004-12-28
BR0211360A (pt)	2004-07-13
EP2335700A1 (de)	2011-06-22
EA200400113A1 (ru)	2004-08-26
US20060160798A1 (en)	2006-07-20
KR20040023674A (ko)	2004-03-18
US20090087409A1 (en)	2009-04-02
SI1414797T1 (sl)	2008-06-30
NO20040322L (no)	2004-02-26
EP1414797B1 (de)	2008-01-02
EA007722B1 (ru)	2006-12-29
PE20030305A1 (es)	2003-04-22
HUP0401784A3 (en)	2011-03-28
DE60224400D1 (de)	2008-02-14
CA2450033A1 (en)	2003-02-06
US7157486B2 (en)	2007-01-02
RS50843B (sr)	2010-08-31
EP1414441B1 (de)	2008-01-02
US7141574B2 (en)	2006-11-28
MEP59608A (en)	2011-05-10
CY1107355T1 (el)	2012-12-19
ES2299591T3 (es)	2008-06-01
US20060293306A1 (en)	2006-12-28
AR037495A1 (es)	2004-11-17
PT1414797E (pt)	2008-02-14
IL222761A0 (en)	2012-12-31
WO2003010140A2 (en)	2003-02-06
DE60224401D1 (de)	2008-02-14
CN102424680A (zh)	2012-04-25
CN1558759B (zh)	2012-01-25
HRP20040073A2 (en)	2004-06-30
HRP20040072A2 (en)	2004-06-30
CN1610546A (zh)	2005-04-27
CY1107354T1 (el)	2012-12-19

Publication	Publication Date	Title
IL222761A0 (en)	2012-12-31	Viral polymerase inhibitors
WO2002004425A3 (en)	2002-04-25	Viral polymerase inhibitors
IL169777A0 (en)	2007-07-04	Viral polymerase inhibitors
HUP0400039A3 (en)	2004-10-28	Hcv polymerase inhibitor assay
EP1418949A4 (de)	2009-03-04	Dna-methylierungshemmer
AU2002360673A8 (en)	2003-06-30	Gp41 inhibitor
AU2002354843A1 (en)	2003-03-03	Viral polymerase inhibitors
GB0109278D0 (en)	2001-05-30	Enzyme inhibitors
AU2002347346A8 (en)	2003-06-17	Dna vaccine
GB0201267D0 (en)	2002-03-06	Releasable clip
GB0130521D0 (en)	2002-02-06	RNA polymerase
GB0130520D0 (en)	2002-02-06	RNA polymerase
GB0102936D0 (en)	2001-03-21	Gene Silencing Gene
GB0130981D0 (en)	2002-02-13	Polymerase inactivation
GB0130983D0 (en)	2002-02-13	Polymerase inactivation
GB0130523D0 (en)	2002-02-06	DNA polymerase
GB0130526D0 (en)	2002-02-06	DNA polymerase
GB0130528D0 (en)	2002-02-06	DNA polymerase
GB2374414B (en)	2005-02-23	Enzyme-coupled assay
GB0116818D0 (en)	2001-08-29	DNA viral infections
GB0313251D0 (en)	2003-07-16	Viral inhibitors
GB0216030D0 (en)	2002-08-21	DNA viral infections
GB0122730D0 (en)	2001-11-14	Gene Linkakge
GB0116360D0 (en)	2001-08-29	Gene PRPC8
GB0128769D0 (en)	2002-01-23	Gene

Legal Events

Date	Code	Title
2013-03-24	FF	Patent granted
2013-04-30	KB	Patent renewed
2017-02-28	MM9K	Patent not in force due to non-payment of renewal fees