IE39292B1 - 17 hydroxy 16,16-dimethylestr-4-en-3-one - Google Patents
17 hydroxy 16,16-dimethylestr-4-en-3-oneInfo
- Publication number
- IE39292B1 IE39292B1 IE1123/74A IE112374A IE39292B1 IE 39292 B1 IE39292 B1 IE 39292B1 IE 1123/74 A IE1123/74 A IE 1123/74A IE 112374 A IE112374 A IE 112374A IE 39292 B1 IE39292 B1 IE 39292B1
- Authority
- IE
- Ireland
- Prior art keywords
- dimethylestr
- hydroxy
- us3853926a
- antisebum
- activities
- Prior art date
Links
- JYCITEUSLNKPHC-UHFFFAOYSA-N 17-hydroxy-13,16,16-trimethyl-1,2,6,7,8,9,10,11,12,14,15,17-dodecahydrocyclopenta[a]phenanthren-3-one Chemical compound C1CC2=CC(=O)CCC2C2C1C1CC(C)(C)C(O)C1(C)CC2 JYCITEUSLNKPHC-UHFFFAOYSA-N 0.000 title 1
- 230000002280 anti-androgenic effect Effects 0.000 abstract 1
- 230000002086 anti-sebum Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- JYCITEUSLNKPHC-URNBORRASA-N metogest Chemical compound C1CC2=CC(=O)CC[C@@H]2[C@@H]2[C@@H]1[C@@H]1CC(C)(C)[C@H](O)[C@@]1(C)CC2 JYCITEUSLNKPHC-URNBORRASA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Fats And Perfumes (AREA)
- Dental Preparations (AREA)
- Detergent Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Preparation of 17 beta -hydroxy-16,16-dimethylestr-4-en-3-one and its unexpected antiandrogenic and antisebum activities are disclosed.
[US3853926A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00364340A US3853926A (en) | 1973-05-29 | 1973-05-29 | 17{62 -hydroxy-16,16-dimethylester-4-en-3-one |
Publications (2)
Publication Number | Publication Date |
---|---|
IE39292L IE39292L (en) | 1974-11-29 |
IE39292B1 true IE39292B1 (en) | 1978-09-13 |
Family
ID=23434065
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE1123/74A IE39292B1 (en) | 1973-05-29 | 1974-05-28 | 17 hydroxy 16,16-dimethylestr-4-en-3-one |
Country Status (21)
Country | Link |
---|---|
US (1) | US3853926A (en) |
JP (1) | JPS5019745A (en) |
AR (1) | AR199619A1 (en) |
AT (1) | AT333990B (en) |
BE (1) | BE815626A (en) |
CA (1) | CA1033716A (en) |
CH (1) | CH609705A5 (en) |
DE (1) | DE2425822A1 (en) |
DK (1) | DK132328C (en) |
ES (1) | ES426711A1 (en) |
FI (1) | FI53218C (en) |
FR (1) | FR2231383B1 (en) |
GB (1) | GB1416839A (en) |
HU (1) | HU168555B (en) |
IE (1) | IE39292B1 (en) |
IL (1) | IL44903A (en) |
NL (1) | NL7407122A (en) |
NO (1) | NO140104C (en) |
PH (1) | PH10428A (en) |
SE (1) | SE401835B (en) |
ZA (1) | ZA743304B (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1538227A (en) * | 1975-03-21 | 1979-01-10 | Beecham Group Ltd | 16,16-disubstituted steroids of the androstene series |
FI59534C (en) * | 1979-10-31 | 1981-09-10 | Orion Yhtymae Oy | VAORDMEDEL FOER FRAEMJANDE AV HAORVAEXT OCH HINDRANDE AV MJAELL |
GB9021546D0 (en) * | 1990-10-04 | 1990-11-21 | Beecham Group Plc | Novel composition |
US6355686B1 (en) * | 2000-06-30 | 2002-03-12 | Unilever Home And Personal Care Usa, Division Of Conopco, Inc. | Cosmetic compositions containing substituted amine derivatives |
US6372795B1 (en) * | 2000-06-30 | 2002-04-16 | Unilever Home And Personal Care Usa, A Division Of Conopco, Inc. | Cosmetic compositions containing substituted amide derivatives |
US6355687B1 (en) * | 2000-06-30 | 2002-03-12 | Unilever Home And Personal Care Usa, Division Of Conopco, Inc. | Cosmetic compositions containing substituted iminodibenzyl or fluorene derivatives |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3049555A (en) * | 1959-12-22 | 1962-08-14 | Searle & Co | 3-alkoxy-16-methyl-1, 3, 5 (10)-estratrien-17-ones |
US3280156A (en) * | 1965-10-13 | 1966-10-18 | Searle & Co | 17beta-hydroxyspiro(estr-4-ene-16, 1'-cyclopropan)-3-ones |
-
1973
- 1973-05-29 US US00364340A patent/US3853926A/en not_active Expired - Lifetime
-
1974
- 1974-05-22 ZA ZA00743304A patent/ZA743304B/en unknown
- 1974-05-28 AT AT438674A patent/AT333990B/en not_active IP Right Cessation
- 1974-05-28 PH PH15876A patent/PH10428A/en unknown
- 1974-05-28 JP JP49060202A patent/JPS5019745A/ja active Pending
- 1974-05-28 DE DE19742425822 patent/DE2425822A1/en not_active Withdrawn
- 1974-05-28 DK DK289274A patent/DK132328C/en active
- 1974-05-28 IE IE1123/74A patent/IE39292B1/en unknown
- 1974-05-28 NL NL7407122A patent/NL7407122A/xx not_active Application Discontinuation
- 1974-05-28 GB GB2351174A patent/GB1416839A/en not_active Expired
- 1974-05-28 FI FI1632/74A patent/FI53218C/fi active
- 1974-05-28 NO NO741929A patent/NO140104C/en unknown
- 1974-05-28 ES ES426711A patent/ES426711A1/en not_active Expired
- 1974-05-28 BE BE144827A patent/BE815626A/en unknown
- 1974-05-28 CA CA200,995A patent/CA1033716A/en not_active Expired
- 1974-05-28 SE SE7407031A patent/SE401835B/en unknown
- 1974-05-28 FR FR7418471A patent/FR2231383B1/fr not_active Expired
- 1974-05-28 HU HUSE1731A patent/HU168555B/hu unknown
- 1974-05-28 IL IL44903A patent/IL44903A/en unknown
- 1974-05-29 CH CH735574A patent/CH609705A5/xx not_active IP Right Cessation
- 1974-05-29 AR AR253974A patent/AR199619A1/en active
Also Published As
Publication number | Publication date |
---|---|
NO741929L (en) | 1974-12-02 |
CA1033716A (en) | 1978-06-27 |
AT333990B (en) | 1976-12-27 |
CH609705A5 (en) | 1979-03-15 |
BE815626A (en) | 1974-11-28 |
ES426711A1 (en) | 1976-08-01 |
IL44903A (en) | 1977-05-31 |
SE7407031L (en) | 1974-12-02 |
AR199619A1 (en) | 1974-09-13 |
NL7407122A (en) | 1974-12-03 |
PH10428A (en) | 1977-03-16 |
ZA743304B (en) | 1976-01-28 |
FR2231383A1 (en) | 1974-12-27 |
HU168555B (en) | 1976-05-28 |
DK132328C (en) | 1976-05-31 |
FI53218C (en) | 1978-03-10 |
SE401835B (en) | 1978-05-29 |
DE2425822A1 (en) | 1975-01-02 |
DK132328B (en) | 1975-11-24 |
FI53218B (en) | 1977-11-30 |
IE39292L (en) | 1974-11-29 |
AU6945474A (en) | 1975-12-04 |
FR2231383B1 (en) | 1977-11-04 |
US3853926A (en) | 1974-12-10 |
ATA438674A (en) | 1976-04-15 |
FI163274A (en) | 1974-11-30 |
IL44903A0 (en) | 1974-07-31 |
JPS5019745A (en) | 1975-03-01 |
GB1416839A (en) | 1975-12-10 |
DK289274A (en) | 1975-01-13 |
NO140104C (en) | 1979-07-11 |
NO140104B (en) | 1979-03-26 |
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