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ES426711A1 - 17{62 -hydroxy-16,16-dimethylester-4-en-3-one - Google Patents

17{62 -hydroxy-16,16-dimethylester-4-en-3-one

Info

Publication number
ES426711A1
ES426711A1 ES426711A ES426711A ES426711A1 ES 426711 A1 ES426711 A1 ES 426711A1 ES 426711 A ES426711 A ES 426711A ES 426711 A ES426711 A ES 426711A ES 426711 A1 ES426711 A1 ES 426711A1
Authority
ES
Spain
Prior art keywords
hydroxy
dimethylester
dimethylestr
antisebum
activities
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES426711A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of ES426711A1 publication Critical patent/ES426711A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0018Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Detergent Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Dental Preparations (AREA)

Abstract

Preparation of 17 beta -hydroxy-16,16-dimethylestr-4-en-3-one and its unexpected antiandrogenic and antisebum activities are disclosed.
ES426711A 1973-05-29 1974-05-28 17{62 -hydroxy-16,16-dimethylester-4-en-3-one Expired ES426711A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00364340A US3853926A (en) 1973-05-29 1973-05-29 17{62 -hydroxy-16,16-dimethylester-4-en-3-one

Publications (1)

Publication Number Publication Date
ES426711A1 true ES426711A1 (en) 1976-08-01

Family

ID=23434065

Family Applications (1)

Application Number Title Priority Date Filing Date
ES426711A Expired ES426711A1 (en) 1973-05-29 1974-05-28 17{62 -hydroxy-16,16-dimethylester-4-en-3-one

Country Status (21)

Country Link
US (1) US3853926A (en)
JP (1) JPS5019745A (en)
AR (1) AR199619A1 (en)
AT (1) AT333990B (en)
BE (1) BE815626A (en)
CA (1) CA1033716A (en)
CH (1) CH609705A5 (en)
DE (1) DE2425822A1 (en)
DK (1) DK132328C (en)
ES (1) ES426711A1 (en)
FI (1) FI53218C (en)
FR (1) FR2231383B1 (en)
GB (1) GB1416839A (en)
HU (1) HU168555B (en)
IE (1) IE39292B1 (en)
IL (1) IL44903A (en)
NL (1) NL7407122A (en)
NO (1) NO140104C (en)
PH (1) PH10428A (en)
SE (1) SE401835B (en)
ZA (1) ZA743304B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1538227A (en) * 1975-03-21 1979-01-10 Beecham Group Ltd 16,16-disubstituted steroids of the androstene series
FI59534C (en) * 1979-10-31 1981-09-10 Orion Yhtymae Oy VAORDMEDEL FOER FRAEMJANDE AV HAORVAEXT OCH HINDRANDE AV MJAELL
GB9021546D0 (en) * 1990-10-04 1990-11-21 Beecham Group Plc Novel composition
US6372795B1 (en) * 2000-06-30 2002-04-16 Unilever Home And Personal Care Usa, A Division Of Conopco, Inc. Cosmetic compositions containing substituted amide derivatives
US6355687B1 (en) * 2000-06-30 2002-03-12 Unilever Home And Personal Care Usa, Division Of Conopco, Inc. Cosmetic compositions containing substituted iminodibenzyl or fluorene derivatives
US6355686B1 (en) * 2000-06-30 2002-03-12 Unilever Home And Personal Care Usa, Division Of Conopco, Inc. Cosmetic compositions containing substituted amine derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3049555A (en) * 1959-12-22 1962-08-14 Searle & Co 3-alkoxy-16-methyl-1, 3, 5 (10)-estratrien-17-ones
US3280156A (en) * 1965-10-13 1966-10-18 Searle & Co 17beta-hydroxyspiro(estr-4-ene-16, 1'-cyclopropan)-3-ones

Also Published As

Publication number Publication date
NO140104B (en) 1979-03-26
JPS5019745A (en) 1975-03-01
ATA438674A (en) 1976-04-15
FI163274A7 (en) 1974-11-30
IL44903A (en) 1977-05-31
NO741929L (en) 1974-12-02
IL44903A0 (en) 1974-07-31
ZA743304B (en) 1976-01-28
DE2425822A1 (en) 1975-01-02
CH609705A5 (en) 1979-03-15
FI53218B (en) 1977-11-30
AU6945474A (en) 1975-12-04
AT333990B (en) 1976-12-27
DK132328C (en) 1976-05-31
FI53218C (en) 1978-03-10
GB1416839A (en) 1975-12-10
IE39292B1 (en) 1978-09-13
HU168555B (en) 1976-05-28
SE7407031L (en) 1974-12-02
NL7407122A (en) 1974-12-03
PH10428A (en) 1977-03-16
AR199619A1 (en) 1974-09-13
FR2231383A1 (en) 1974-12-27
CA1033716A (en) 1978-06-27
FR2231383B1 (en) 1977-11-04
IE39292L (en) 1974-11-29
BE815626A (en) 1974-11-28
DK132328B (en) 1975-11-24
SE401835B (en) 1978-05-29
NO140104C (en) 1979-07-11
DK289274A (en) 1975-01-13
US3853926A (en) 1974-12-10

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