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HUP0100964A2 - Gyógyszerészeti kombinációk tramadollal - Google Patents

Gyógyszerészeti kombinációk tramadollal

Info

Publication number
HUP0100964A2
HUP0100964A2 HU0100964A HUP0100964A HUP0100964A2 HU P0100964 A2 HUP0100964 A2 HU P0100964A2 HU 0100964 A HU0100964 A HU 0100964A HU P0100964 A HUP0100964 A HU P0100964A HU P0100964 A2 HUP0100964 A2 HU P0100964A2
Authority
HU
Hungary
Prior art keywords
pharmaceutical combinations
combinations containing
containing tramadol
migraine
pharmaceutically acceptable
Prior art date
Application number
HU0100964A
Other languages
English (en)
Inventor
Helmut Momberger
Marc Raber
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of HUP0100964A2 publication Critical patent/HUP0100964A2/hu
Publication of HUP0100964A3 publication Critical patent/HUP0100964A3/hu
Publication of HU225656B1 publication Critical patent/HU225656B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/133—Amines having hydroxy groups, e.g. sphingosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

A jelen találmány hatóanyagként tramadolt vagy egy enantiomerjét vagyegy gyógyszerészetileg elfogadható sóját és metocloprámidot,domperidont vagy más prokinetikus és antiemetikus hatású anyagot vagyezek gyógyszerészetileg elfogadható sóját tartalmazó gyógyszerészetikombinációk alkalmazására vonatkozik migrén és migrénszerű fejfájások,valamint olyan fájdalmas állapotok kezelésére, amelyek émelygésselés/vagy hányással (például kemoterápia alatt) és/vagy késleltetettgyomorkiürüléssel járnak együtt (például posztoperatív, diabetikusgyomorparézisnél). Ó
HU0100964A 1998-02-21 1999-02-17 Pharmaceutical combinations containing tramadol HU225656B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19807535A DE19807535A1 (de) 1998-02-21 1998-02-21 Pharmazeutische Kombinationen mit Tramadol
PCT/DE1999/000428 WO1999042095A1 (de) 1998-02-21 1999-02-17 Pharmazeutische kombinationen mit tramadol

Publications (3)

Publication Number Publication Date
HUP0100964A2 true HUP0100964A2 (hu) 2001-08-28
HUP0100964A3 HUP0100964A3 (en) 2003-09-29
HU225656B1 HU225656B1 (en) 2007-05-29

Family

ID=7858642

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0100964A HU225656B1 (en) 1998-02-21 1999-02-17 Pharmaceutical combinations containing tramadol

Country Status (26)

Country Link
EP (1) EP1056448B1 (hu)
JP (1) JP2002503689A (hu)
KR (1) KR100567154B1 (hu)
CN (1) CN1141937C (hu)
AR (1) AR018102A1 (hu)
AT (1) ATE257700T1 (hu)
AU (1) AU748993B2 (hu)
BG (1) BG64888B1 (hu)
BR (1) BR9909211A (hu)
CZ (1) CZ291941B6 (hu)
DE (2) DE19807535A1 (hu)
DK (1) DK1056448T3 (hu)
EA (1) EA002166B1 (hu)
ES (1) ES2212549T3 (hu)
HK (1) HK1035143A1 (hu)
HU (1) HU225656B1 (hu)
IL (1) IL137505A (hu)
NO (1) NO327860B1 (hu)
NZ (1) NZ506020A (hu)
PL (1) PL204075B1 (hu)
PT (1) PT1056448E (hu)
SK (1) SK284937B6 (hu)
TR (1) TR200002411T2 (hu)
TW (1) TWI228040B (hu)
WO (1) WO1999042095A1 (hu)
ZA (1) ZA991212B (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000032558A1 (en) * 1998-12-02 2000-06-08 Darwin Discovery Limited Therapeutic product and its use
DE19940944B4 (de) * 1999-08-31 2006-10-12 Grünenthal GmbH Retardierte, orale, pharmazeutische Darreichungsformen
US20030119916A1 (en) 2000-03-01 2003-06-26 David Fowler Treatment of functional gastrointestinal disorders
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
DE10108122A1 (de) 2001-02-21 2002-10-02 Gruenenthal Gmbh Arzneimittel auf Basis von Tramadol
DE10361596A1 (de) * 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102004020220A1 (de) * 2004-04-22 2005-11-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
US7553858B2 (en) * 2003-12-17 2009-06-30 Meda Pharma Gmbh & Co. Kg Combination of flupirtine and tramadol
CA2665841C (en) 2006-10-09 2016-04-05 Charleston Laboratories, Inc. Pharmaceutical compositions
WO2009089494A2 (en) 2008-01-09 2009-07-16 Charleston Laboratories, Inc. Pharmaceutical compositions
AU2009241847B2 (en) 2008-04-28 2014-07-10 Zogenix, Inc. Novel formulations for treatment of migraine
US20130213393A1 (en) 2009-12-22 2013-08-22 Evoke Pharma, Inc. Nasal formulations of metoclopramide
CA2767576C (en) 2009-07-08 2020-03-10 Charleston Laboratories Inc. Pharmaceutical compositions comprising an antiemetic and an opioid analgesic
BR112016023628A2 (pt) * 2014-04-10 2018-05-15 Charleston Laboratories Inc composições farmacêuticas.
CA3055170A1 (en) 2016-03-04 2017-09-08 Charleston Laboratories, Inc. Pharmaceutical compositions
EP3554489A4 (en) * 2016-12-15 2020-06-17 Evoke Pharma, Inc. TREATMENT OF MODERATE AND SERIOUS GASTROPARESIS
JP7195660B1 (ja) 2021-09-09 2022-12-26 壽製薬株式会社 口腔内崩壊錠

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU528098B2 (en) * 1978-11-16 1983-04-14 Beecham Group Plc Analgesic tablet
AU528310B2 (en) * 1978-11-16 1983-04-21 Beecham Group Plc Composition of paracetamol and metoclopramide
CA2020018A1 (en) * 1990-06-27 1991-12-28 Don L. Simmons Method and composition for treating the migraine complex
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
FR2712809B1 (fr) * 1993-11-26 1996-04-12 Union Pharma Scient Appl Nouvelle composition pharmaceutique destinée à la préparation d'une poudre stable contenant, à titre d'ingrédient actif, une association d'acide acétylsalicylique et de métoclopramide.
FR2720936B1 (fr) * 1994-06-08 1997-04-30 Synthelabo Poudres à base de métoclopramide et de paracétamol ou de dérivés d'acide acétylsalicylique.
GB9523566D0 (en) * 1995-11-17 1996-01-17 Euro Celtique Sa Pharmaceutical formulation
FR2741532B1 (fr) * 1995-11-28 1998-08-21 Bouchara Sa Nouvelles compositions pharmaceutiques a action antimigraineuse et leur mode de preparation
GB2313309B (en) * 1996-05-24 2000-01-26 Ninh Thuy On Pharmaceutical compositions comprising a nonsteroidal anti-inflammatory drug and domperidone in the treatment of migraine

Also Published As

Publication number Publication date
PL342546A1 (en) 2001-06-18
NO327860B1 (no) 2009-10-05
SK12172000A3 (sk) 2001-04-09
SK284937B6 (sk) 2006-02-02
CZ291941B6 (cs) 2003-06-18
HU225656B1 (en) 2007-05-29
DE59908305D1 (de) 2004-02-19
KR20010041110A (ko) 2001-05-15
ZA991212B (en) 1999-08-03
NO20004143D0 (no) 2000-08-18
AU748993B2 (en) 2002-06-13
ATE257700T1 (de) 2004-01-15
DK1056448T3 (da) 2004-05-17
BG64888B1 (bg) 2006-08-31
PT1056448E (pt) 2004-05-31
TWI228040B (en) 2005-02-21
WO1999042095A1 (de) 1999-08-26
IL137505A (en) 2005-07-25
IL137505A0 (en) 2001-07-24
AU3514899A (en) 1999-09-06
HUP0100964A3 (en) 2003-09-29
PL204075B1 (pl) 2009-12-31
JP2002503689A (ja) 2002-02-05
TR200002411T2 (tr) 2000-12-21
EP1056448B1 (de) 2004-01-14
AR018102A1 (es) 2001-10-31
EP1056448A1 (de) 2000-12-06
NO20004143L (no) 2000-09-27
KR100567154B1 (ko) 2006-04-04
CZ20002939A3 (cs) 2000-12-13
DE19807535A1 (de) 1999-08-26
HK1035143A1 (en) 2001-11-16
NZ506020A (en) 2002-05-31
EA200000862A1 (ru) 2001-02-26
BG104758A (en) 2001-04-30
CN1141937C (zh) 2004-03-17
EA002166B1 (ru) 2001-12-24
CN1291092A (zh) 2001-04-11
ES2212549T3 (es) 2004-07-16
BR9909211A (pt) 2000-11-14

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Legal Events

Date Code Title Description
HC9A Change of name, address

Owner name: MEDA PHARMA GMBH & CO. KG, DE

Free format text: FORMER OWNER(S): ASTA MEDICA AG, DE; ASTA MEDICA HEALTH PRODUCTS GMBH & CO. KG, DE; VIATRIS GMBH & CO. KG, DE

MM4A Lapse of definitive patent protection due to non-payment of fees