HUE048852T2 - Putreszcint termelõ mikroorganizmusok és eljárás putreszcin elõállítására azok alkalmazásával - Google Patents
Putreszcint termelõ mikroorganizmusok és eljárás putreszcin elõállítására azok alkalmazásávalInfo
- Publication number
- HUE048852T2 HUE048852T2 HUE14768563A HUE14768563A HUE048852T2 HU E048852 T2 HUE048852 T2 HU E048852T2 HU E14768563 A HUE14768563 A HU E14768563A HU E14768563 A HUE14768563 A HU E14768563A HU E048852 T2 HUE048852 T2 HU E048852T2
- Authority
- HU
- Hungary
- Prior art keywords
- putrescine
- microorganisms
- same
- productivity
- producing
- Prior art date
Links
- KIDHWZJUCRJVML-UHFFFAOYSA-N putrescine Chemical compound NCCCCN KIDHWZJUCRJVML-UHFFFAOYSA-N 0.000 title 4
- 239000005700 Putrescine Substances 0.000 title 2
- 244000005700 microbiome Species 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1018—Carboxy- and carbamoyl transferases (2.1.3)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/001—Amines; Imines
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01038—N-Acetyl-gamma-glutamyl-phosphate reductase (1.2.1.38)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y201/00—Transferases transferring one-carbon groups (2.1)
- C12Y201/03—Carboxy- and carbamoyltransferases (2.1.3)
- C12Y201/03003—Ornithine carbamoyltransferase (2.1.3.3)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01035—Glutamate N-acetyltransferase (2.3.1.35)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y206/00—Transferases transferring nitrogenous groups (2.6)
- C12Y206/01—Transaminases (2.6.1)
- C12Y206/01011—Acetylornithine transaminase (2.6.1.11)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/02—Phosphotransferases with a carboxy group as acceptor (2.7.2)
- C12Y207/02008—Acetylglutamate kinase (2.7.2.8)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01007—Benzoylformate decarboxylase (4.1.1.7)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2330/00—Production
- C12N2330/50—Biochemical production, i.e. in a transformed host cell
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/46—Amines, e.g. putrescine
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20130030020 | 2013-03-20 | ||
| KR1020140017243A KR101607741B1 (ko) | 2013-03-20 | 2014-02-14 | 퓨트레신 생산 재조합 미생물 및 이를 이용한 퓨트레신 생산방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE048852T2 true HUE048852T2 (hu) | 2020-08-28 |
Family
ID=51758636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE14768563A HUE048852T2 (hu) | 2013-03-20 | 2014-02-25 | Putreszcint termelõ mikroorganizmusok és eljárás putreszcin elõállítására azok alkalmazásával |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10221433B2 (hu) |
| EP (1) | EP2977443B1 (hu) |
| JP (1) | JP6297134B2 (hu) |
| KR (1) | KR101607741B1 (hu) |
| CN (1) | CN105492593B (hu) |
| AU (1) | AU2014238707B2 (hu) |
| BR (1) | BR112015018599B1 (hu) |
| HU (1) | HUE048852T2 (hu) |
| MY (1) | MY172080A (hu) |
| RU (1) | RU2665825C2 (hu) |
| TW (2) | TWI632238B (hu) |
| WO (1) | WO2014148743A1 (hu) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101607741B1 (ko) * | 2013-03-20 | 2016-03-31 | 씨제이제일제당 (주) | 퓨트레신 생산 재조합 미생물 및 이를 이용한 퓨트레신 생산방법 |
| PL3135759T3 (pl) * | 2014-04-25 | 2019-05-31 | Cj Cheiljedang Corp | Wariant szczepu wytwarzający putrescynę i sposób wytwarzania putrescyny z jego zastosowaniem |
| AU2015250514B2 (en) | 2014-04-25 | 2018-05-17 | Cj Cheiljedang Corporation | Microorganisms for Producing Diamine and Process for Producing Diamine Using Them |
| DK3135757T3 (da) * | 2014-04-25 | 2019-05-20 | Cj Cheiljedang Corp | Diaminproducerende mikroorganisme og fremgangsmåde til fremstilling af diamin under anvendelse af samme |
| KR101773135B1 (ko) | 2015-05-08 | 2017-08-30 | 씨제이제일제당 주식회사 | 1,4-디아미노부탄의 정제방법 |
| KR101813759B1 (ko) * | 2015-06-24 | 2018-01-02 | 씨제이제일제당 (주) | 퓨트레신 또는 오르니틴 생산 미생물 및 이를 이용한 퓨트레신 또는 오르니틴 생산방법 |
| KR101735935B1 (ko) * | 2015-07-20 | 2017-05-16 | 씨제이제일제당 (주) | 퓨트레신 또는 오르니틴 생산 미생물 및 이를 이용한 퓨트레신 또는 오르니틴 생산방법 |
| JP6663757B2 (ja) * | 2016-03-11 | 2020-03-13 | 日清ファルマ株式会社 | ポリアミン高含有酵母及びその製造方法 |
| KR101871037B1 (ko) * | 2016-03-15 | 2018-06-26 | 씨제이제일제당 (주) | 퓨트레신을 생산하는 미생물 및 이를 이용한 퓨트레신 생산 방법 |
| KR101941775B1 (ko) | 2017-06-14 | 2019-01-24 | 씨제이제일제당 (주) | 신규 폴리펩타이드 및 이를 이용한 오르니틴계 산물 생산방법 |
| KR101937569B1 (ko) * | 2017-06-14 | 2019-01-11 | 씨제이제일제당 (주) | 신규 폴리펩타이드 및 이를 이용한 오르니틴계 산물 생산방법 |
| KR102011394B1 (ko) * | 2017-07-19 | 2019-10-22 | 씨제이제일제당 주식회사 | 퓨트레신을 생산하는 미생물 및 이를 이용한 퓨트레신 생산방법 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR920000933B1 (ko) | 1989-07-28 | 1992-01-31 | 삼성전관 주식회사 | 평면 방전형 칼라 방전 표시 패널 |
| JP4623825B2 (ja) | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | 新規ポリヌクレオチド |
| JP4479283B2 (ja) | 2004-03-04 | 2010-06-09 | 味の素株式会社 | Ｌ−システイン生産菌及びｌ−システインの製造法 |
| JP4836948B2 (ja) * | 2004-07-15 | 2011-12-14 | ディーエスエム アイピー アセッツ ビー．ブイ． | １，４−ブタンジアミンの生化学合成 |
| KR100620092B1 (ko) | 2004-12-16 | 2006-09-08 | 씨제이 주식회사 | 코리네박테리움 속 세포로부터 유래된 신규한 프로모터서열, 그를 포함하는 발현 카세트 및 벡터, 상기 벡터를포함하는 숙주 세포 및 그를 이용하여 유전자를 발현하는방법 |
| KR100882259B1 (ko) | 2006-10-12 | 2009-02-09 | 주식회사 코캣 | 탈질, 탈황, 함산소 화합물 제조를 위한 탄화수소 기질의선택산화 방법 |
| RU2355759C1 (ru) * | 2007-08-14 | 2009-05-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПОЛУЧЕНИЯ АРОМАТИЧЕСКОЙ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia, В КОТОРОЙ ИНАКТИВИРОВАН ГЕН ydiB, СПОСОБ ПОЛУЧЕНИЯ СЛОЖНОГО ЭФИРА НИЗШИХ АЛКИЛОВ АЛЬФА-L-АСПАРТИЛ-L-ФЕНИЛАЛАНИНА |
| KR100930203B1 (ko) | 2008-01-28 | 2009-12-07 | 씨제이제일제당 (주) | 개량된 프로모터 및 이를 이용한 ｌ-라이신의 생산 방법 |
| JP5675353B2 (ja) | 2008-04-10 | 2015-02-25 | コリア アドバンスド インスティチュート オブ サイエンス アンド テクノロジィ | プトレッシン高生成能を有する変異微生物及びこれを用いたプトレッシンの製造方法 |
| KR20120003634A (ko) | 2010-07-05 | 2012-01-11 | 현대위아 주식회사 | 차륜용 회전 지지 장치 |
| KR101348461B1 (ko) * | 2010-12-08 | 2014-01-08 | 씨제이제일제당 (주) | 퓨트레신을 생산하는 미생물 및 이를 이용하여 퓨트레신을 생산하는 방법 |
| EP2678421B1 (en) | 2011-02-22 | 2018-04-11 | Basf Se | Processes and recombinant microorganisms for the production of cadaverine |
| KR101493585B1 (ko) * | 2012-01-11 | 2015-02-16 | 씨제이제일제당 (주) | 퓨트레신 생산능이 향상된 재조합 미생물 및 이를 이용하여 퓨트레신을 생산하는 방법 |
| KR101493586B1 (ko) * | 2012-01-20 | 2015-02-16 | 씨제이제일제당 (주) | 퓨트레신 생산능이 향상된 재조합 미생물 및 이를 이용하여 퓨트레신을 생산하는 방법 |
| KR101607741B1 (ko) | 2013-03-20 | 2016-03-31 | 씨제이제일제당 (주) | 퓨트레신 생산 재조합 미생물 및 이를 이용한 퓨트레신 생산방법 |
| PL3135759T3 (pl) * | 2014-04-25 | 2019-05-31 | Cj Cheiljedang Corp | Wariant szczepu wytwarzający putrescynę i sposób wytwarzania putrescyny z jego zastosowaniem |
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2014
- 2014-02-14 KR KR1020140017243A patent/KR101607741B1/ko active IP Right Grant
- 2014-02-25 AU AU2014238707A patent/AU2014238707B2/en active Active
- 2014-02-25 CN CN201480017057.0A patent/CN105492593B/zh active Active
- 2014-02-25 US US14/778,383 patent/US10221433B2/en active Active
- 2014-02-25 JP JP2016504226A patent/JP6297134B2/ja active Active
- 2014-02-25 MY MYPI2015001984A patent/MY172080A/en unknown
- 2014-02-25 BR BR112015018599-1A patent/BR112015018599B1/pt active IP Right Grant
- 2014-02-25 WO PCT/KR2014/001509 patent/WO2014148743A1/ko active Application Filing
- 2014-02-25 RU RU2015142261A patent/RU2665825C2/ru active
- 2014-02-25 HU HUE14768563A patent/HUE048852T2/hu unknown
- 2014-02-25 EP EP14768563.0A patent/EP2977443B1/en active Active
- 2014-03-19 TW TW103110374A patent/TWI632238B/zh active
- 2014-03-19 TW TW105108481A patent/TWI657142B/zh active
-
2019
- 2019-01-11 US US16/246,082 patent/US11053524B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| TW201441367A (zh) | 2014-11-01 |
| US10221433B2 (en) | 2019-03-05 |
| CN105492593B (zh) | 2019-08-09 |
| RU2015142261A (ru) | 2017-04-26 |
| BR112015018599A2 (pt) | 2017-08-22 |
| MY172080A (en) | 2019-11-13 |
| EP2977443A1 (en) | 2016-01-27 |
| EP2977443A4 (en) | 2016-09-07 |
| BR112015018599B1 (pt) | 2022-12-13 |
| WO2014148743A1 (ko) | 2014-09-25 |
| US11053524B2 (en) | 2021-07-06 |
| US20170002386A1 (en) | 2017-01-05 |
| TW201623617A (zh) | 2016-07-01 |
| KR20140115244A (ko) | 2014-09-30 |
| AU2014238707A1 (en) | 2015-07-23 |
| JP6297134B2 (ja) | 2018-03-20 |
| JP2016514466A (ja) | 2016-05-23 |
| TWI632238B (zh) | 2018-08-11 |
| CN105492593A (zh) | 2016-04-13 |
| AU2014238707B2 (en) | 2017-08-31 |
| EP2977443B1 (en) | 2020-04-08 |
| TWI657142B (zh) | 2019-04-21 |
| KR101607741B1 (ko) | 2016-03-31 |
| US20190136274A1 (en) | 2019-05-09 |
| RU2665825C2 (ru) | 2018-09-04 |
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