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SG11201800254SA - Microorganisms for producing putrescine or ornithine and process for producing putrescine or ornithine using them - Google Patents

Microorganisms for producing putrescine or ornithine and process for producing putrescine or ornithine using them

Info

Publication number
SG11201800254SA
SG11201800254SA SG11201800254SA SG11201800254SA SG11201800254SA SG 11201800254S A SG11201800254S A SG 11201800254SA SG 11201800254S A SG11201800254S A SG 11201800254SA SG 11201800254S A SG11201800254S A SG 11201800254SA SG 11201800254S A SG11201800254S A SG 11201800254SA
Authority
SG
Singapore
Prior art keywords
ornithine
producing putrescine
microorganisms
putrescine
producing
Prior art date
Application number
SG11201800254SA
Inventor
Su Jin Park
Young Lyeol Yang
Hye Won Um
Hong Xian Li
Kyoung Min Lee
Baek Seok Lee
Hyo Hyoung Lee
Hee Kyoung Jung
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of SG11201800254SA publication Critical patent/SG11201800254SA/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1003Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1018Carboxy- and carbamoyl transferases (2.1.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93Ligases (6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/001Amines; Imines
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/10Citrulline; Arginine; Ornithine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y201/00Transferases transferring one-carbon groups (2.1)
    • C12Y201/03Carboxy- and carbamoyltransferases (2.1.3)
    • C12Y201/03003Ornithine carbamoyltransferase (2.1.3.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01001Amino-acid N-acetyltransferase (2.3.1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01008Phosphate acetyltransferase (2.3.1.8)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01035Glutamate N-acetyltransferase (2.3.1.35)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/02Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02001Acetate kinase (2.7.2.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y305/00Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01016Acetylornithine deacetylase (3.5.1.16)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/01Carboxy-lyases (4.1.1)
    • C12Y401/01017Ornithine decarboxylase (4.1.1.17)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y602/00Ligases forming carbon-sulfur bonds (6.2)
    • C12Y602/01Acid-Thiol Ligases (6.2.1)
    • C12Y602/01001Acetate-CoA ligase (6.2.1.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201800254SA 2015-07-20 2016-07-19 Microorganisms for producing putrescine or ornithine and process for producing putrescine or ornithine using them SG11201800254SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020150102624A KR101735935B1 (en) 2015-07-20 2015-07-20 Microorganisms for producing putrescine or ornithine and process for producing putrescine or ornithine using them
PCT/KR2016/007841 WO2017014532A1 (en) 2015-07-20 2016-07-19 Microorganism for producing putrescine or ornithine and method for producing putrescine or ornithine by using same

Publications (1)

Publication Number Publication Date
SG11201800254SA true SG11201800254SA (en) 2018-02-27

Family

ID=57326155

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201800254SA SG11201800254SA (en) 2015-07-20 2016-07-19 Microorganisms for producing putrescine or ornithine and process for producing putrescine or ornithine using them

Country Status (16)

Country Link
US (4) US10640753B2 (en)
EP (1) EP3141598B1 (en)
JP (1) JP6543758B2 (en)
KR (1) KR101735935B1 (en)
CN (1) CN107922955B (en)
AU (1) AU2016297226B2 (en)
CA (1) CA2992970C (en)
CL (1) CL2018000111A1 (en)
MX (2) MX2018000337A (en)
MY (1) MY184142A (en)
NZ (1) NZ738658A (en)
PH (1) PH12018500150A1 (en)
RU (2) RU2708165C2 (en)
SG (1) SG11201800254SA (en)
TW (1) TWI635176B (en)
WO (1) WO2017014532A1 (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101941775B1 (en) * 2017-06-14 2019-01-24 씨제이제일제당 (주) Novel polypeptide and a method for producing a desired product derived from ornithine using the same
KR101937569B1 (en) * 2017-06-14 2019-01-11 씨제이제일제당 (주) Novel polypeptide and a method for producing a desired product derived from ornithine using the same
KR102011394B1 (en) * 2017-07-19 2019-10-22 씨제이제일제당 주식회사 Microorganism producing putrescine and method of producing putrescine using the microorganism
CN108642100B (en) * 2018-05-16 2020-12-29 江南大学 Method for synthesizing L-ornithine in corynebacterium crenatum
JP2022538229A (en) * 2019-07-02 2022-09-01 コデクシス, インコーポレイテッド Engineered Acetate Kinase Variant Enzymes
KR102246288B1 (en) * 2020-08-13 2021-04-29 씨제이제일제당 주식회사 Microorganisms for producing putrescine and process for producing putrescine using them
PE20231508A1 (en) * 2020-10-28 2023-09-26 Ajinomoto Kk L-AMINO ACID PRODUCTION METHOD
KR20230054183A (en) * 2021-10-15 2023-04-24 씨제이제일제당 (주) A genus of Corynebacterium microorganism for producing L- arginine and a method for producing L-arginine using the same

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JPS6066989A (en) 1983-09-24 1985-04-17 Kyowa Hakko Kogyo Co Ltd Production of l-arginine
JPH0755155B2 (en) 1986-09-10 1995-06-14 協和醗酵工業株式会社 Amino acid manufacturing method
JP4682454B2 (en) * 2000-06-28 2011-05-11 味の素株式会社 Process for producing novel mutant N-acetylglutamate synthase and L-arginine
DE60038560T2 (en) * 2000-10-27 2009-06-25 Ajinomoto Co., Inc. Process for the fermentative production of L-arginine
EP1664318B1 (en) * 2004-01-30 2009-09-23 Ajinomoto Co., Inc. L-amino acid-producing microorganism and method for producing l-amino acid
AU2005261861B2 (en) 2004-07-15 2010-08-26 Dsm Ip Assets B.V. Biochemical synthesis of 1,4-butanediamine
KR100620092B1 (en) 2004-12-16 2006-09-08 씨제이 주식회사 Novel promoter nucleic acid derived from corynebacterium genus bacteria expression cassette comprising the promoter and vector comprising the cassette host cell comprising the vector and method for expressing a gene using the cell
DE102005020538A1 (en) * 2005-05-03 2006-11-23 Degussa Ag Process for the preparation of L-amino acids using improved strains of the family Enterobacteriaceae
WO2007086608A1 (en) * 2006-01-27 2007-08-02 Ajinomoto Co., Inc. Method for producing l-amino acid
US7993888B2 (en) * 2006-02-24 2011-08-09 Mitsubishi Chemical Corporation Bacterium having enhanced 2-oxoglutarate dehydrogenase activity
JP2009060791A (en) * 2006-03-30 2009-03-26 Ajinomoto Co Inc L-amino acid-producing bacterium and method for producing l-amino acid
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KR100930203B1 (en) 2008-01-28 2009-12-07 씨제이제일제당 (주) Improved promoter and method for producing L-lysine using the same
CN101679964B (en) * 2008-04-10 2013-12-25 韩国科学技术院 Mutant microorganism having high putrescine productivity and method for producing putrescine using the same
KR101126041B1 (en) 2008-04-10 2012-03-19 씨제이제일제당 (주) A transformation vector using transposon, a microorganism transformed with the vector and method of producing l-lysine using the microorganism
JP2012223091A (en) * 2009-08-25 2012-11-15 Ajinomoto Co Inc Method for producing l-amino acid
KR101174267B1 (en) * 2010-01-06 2012-08-14 씨제이제일제당 (주) Corynebacterium glutamicum Variety Producing L-ornithine or L-Arginine and Method for Fabricating the Same
RU2010101135A (en) * 2010-01-15 2011-07-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) (RU) BACTERIA OF THE ENTEROBACTERIACEAE FAMILY - PRODUCER OF L-ASAPPARATE OR METABOLITES, L-ASPARATE DERIVATIVES, AND METHOD OF PRODUCING L-ASAPPARATE OR METABOLITES, PRODUCED L-ASAPPARATE
KR101381048B1 (en) 2010-10-20 2014-04-14 씨제이제일제당 (주) A microorganism producing O-phosphoserine and the method of producing L-cysteine or derivatives thereof from O-phosphoserine using the same
KR101372635B1 (en) 2010-12-08 2014-03-13 씨제이제일제당 (주) Microorganisms for producing ornithine and process for producing ornithine using the same
CN102191291B (en) * 2011-04-25 2013-05-08 武汉远大弘元股份有限公司 Method for producing L-ornithine hydrochloride by genetic engineering bacteria
RU2604806C2 (en) * 2012-01-11 2016-12-10 СиДжей ЧеилДжеданг Корпорейшн Recombinant microorganism with increased ability to produce putrescine, and method of producing putrescine using said microorganism
RU2550269C2 (en) * 2012-08-17 2015-05-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") METHOD OF PRODUCING L-ARGININE USING Enterobacteriaceae BACTERIA, CONTAINING DISRUPTED-ACTIVITY N-ACETYLORNITHINE DEACETYLASE
KR101607741B1 (en) * 2013-03-20 2016-03-31 씨제이제일제당 (주) Microorganisms having putrescine productivity and process for producing putrescine using the same
WO2017127567A1 (en) * 2016-01-19 2017-07-27 Genebiologics, Llc Production of arginine-rich proteins and use as a fertilizer and germination enhancer
CN108642100B (en) * 2018-05-16 2020-12-29 江南大学 Method for synthesizing L-ornithine in corynebacterium crenatum

Also Published As

Publication number Publication date
CL2018000111A1 (en) 2018-05-11
TWI635176B (en) 2018-09-11
MX2018000337A (en) 2018-03-14
KR101735935B1 (en) 2017-05-16
EP3141598B1 (en) 2018-10-31
RU2018104512A3 (en) 2019-08-20
WO2017014532A1 (en) 2017-01-26
KR20170010960A (en) 2017-02-02
NZ738658A (en) 2019-09-27
AU2016297226A1 (en) 2018-01-25
US10640753B2 (en) 2020-05-05
JP6543758B2 (en) 2019-07-10
RU2708165C2 (en) 2019-12-04
CN107922955B (en) 2021-04-27
US11365400B2 (en) 2022-06-21
US11268074B2 (en) 2022-03-08
CN107922955A (en) 2018-04-17
CA2992970A1 (en) 2017-01-26
MX2021007245A (en) 2021-07-15
US10815464B2 (en) 2020-10-27
MY184142A (en) 2021-03-22
EP3141598A2 (en) 2017-03-15
RU2018104512A (en) 2019-08-20
JP2018520687A (en) 2018-08-02
BR112018001231A2 (en) 2018-09-25
US20210054347A1 (en) 2021-02-25
CA2992970C (en) 2019-12-03
US20200190486A1 (en) 2020-06-18
US20200002686A1 (en) 2020-01-02
TW201718863A (en) 2017-06-01
PH12018500150A1 (en) 2018-07-23
AU2016297226B2 (en) 2019-06-27
EP3141598A3 (en) 2017-06-21
RU2721852C1 (en) 2020-05-25
US20180208909A1 (en) 2018-07-26

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