HU9802143D0 - New heterocyclic compounds of 5 members in the ring, process for producing them and pharmaceutical compositions containing them - Google Patents

New heterocyclic compounds of 5 members in the ring, process for producing them and pharmaceutical compositions containing them

Info

Publication number: HU9802143D0
Authority: HU; Hungary
Prior art keywords: members; producing; ring; pharmaceutical compositions; compositions containing
Prior art date: 1997-09-23

Application number

HU9802143A

Other languages

English (en)

Inventor

Wolfgang Schmidt

Dirk Seiffge

Hans Ulrich Stilz

Volkmar Wehner

Original Assignee

Hoechst Marion Roussel De Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-23

Filing date

1998-09-23

Publication date

1998-11-30

1998-09-23 Application filed by Hoechst Marion Roussel De Gmbh filed Critical Hoechst Marion Roussel De Gmbh

1998-11-30 Publication of HU9802143D0 publication Critical patent/HU9802143D0/hu

1999-06-28 Publication of HUP9802143A2 publication Critical patent/HUP9802143A2/hu

1999-11-29 Publication of HUP9802143A3 publication Critical patent/HUP9802143A3/hu

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Crystallography & Structural Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Hematology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Neurosurgery (AREA)
Dermatology (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Ophthalmology & Optometry (AREA)
Vascular Medicine (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Neurology (AREA)

HU9802143A 1997-09-23 1998-09-23 Heterocyclic compounds of 5 members in the ring, process for producing them and pharmaceutical compositions containing them HUP9802143A3 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19741873A DE19741873A1 (de)	1997-09-23	1997-09-23	Neue 5-Ring-Heterocyclen, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate

Publications (3)

Publication Number	Publication Date
HU9802143D0 true HU9802143D0 (en)	1998-11-30
HUP9802143A2 HUP9802143A2 (hu)	1999-06-28
HUP9802143A3 HUP9802143A3 (en)	1999-11-29

Family

ID=7843291

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU9802143A HUP9802143A3 (en)	1997-09-23	1998-09-23	Heterocyclic compounds of 5 members in the ring, process for producing them and pharmaceutical compositions containing them

Country Status (24)

Country	Link
US (1)	US6034238A (hu)
EP (1)	EP0905139B1 (hu)
JP (1)	JP4603104B2 (hu)
KR (1)	KR19990030046A (hu)
CN (1)	CN1216767A (hu)
AT (1)	ATE421524T1 (hu)
AU (1)	AU748579B2 (hu)
BR (1)	BR9803969A (hu)
CA (1)	CA2247735A1 (hu)
CZ (1)	CZ303198A3 (hu)
DE (2)	DE19741873A1 (hu)
HR (1)	HRP980519A2 (hu)
HU (1)	HUP9802143A3 (hu)
ID (1)	ID20915A (hu)
IL (1)	IL126278A0 (hu)
MY (1)	MY134191A (hu)
NO (1)	NO984414L (hu)
NZ (1)	NZ331983A (hu)
PL (1)	PL191149B1 (hu)
RU (1)	RU2240326C2 (hu)
SK (1)	SK129598A3 (hu)
TR (1)	TR199801870A2 (hu)
TW (1)	TW588051B (hu)
ZA (1)	ZA988668B (hu)

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PL323130A1 (en) *	1996-11-15	1998-05-25	Hoechst Ag	Application of heterocyclic compounds in production of a pharmaceutic agent, novel heterocyclic compounds and pharmaceutic agent as such
DE19647380A1 (de) *	1996-11-15	1998-05-20	Hoechst Ag	5-Ring-Heterocyclen als Inhibitoren der Leukozytenadhäsion und VLA-4-Antagonisten
DE19647381A1 (de) *	1996-11-15	1998-05-20	Hoechst Ag	Neue Heterocyclen als Inhibitoren der Leukozytenadhäsion und VLA-4-Antagonisten
WO1998042656A1 (en) *	1997-03-21	1998-10-01	Cytel Corporation	Novel compounds
DE19741235A1 (de) *	1997-09-18	1999-03-25	Hoechst Marion Roussel De Gmbh	Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate

1997
- 1997-09-23 DE DE19741873A patent/DE19741873A1/de not_active Withdrawn
1998
- 1998-09-17 EP EP98117660A patent/EP0905139B1/de not_active Expired - Lifetime
- 1998-09-17 DE DE59814334T patent/DE59814334D1/de not_active Expired - Lifetime
- 1998-09-17 AT AT98117660T patent/ATE421524T1/de not_active IP Right Cessation
- 1998-09-17 IL IL12627898A patent/IL126278A0/xx not_active IP Right Cessation
- 1998-09-21 NZ NZ331983A patent/NZ331983A/en unknown
- 1998-09-21 TR TR1998/01870A patent/TR199801870A2/xx unknown
- 1998-09-21 ID IDP981265A patent/ID20915A/id unknown
- 1998-09-21 CA CA002247735A patent/CA2247735A1/en not_active Abandoned
- 1998-09-21 MY MYPI98004339A patent/MY134191A/en unknown
- 1998-09-21 CZ CZ983031A patent/CZ303198A3/cs unknown
- 1998-09-21 SK SK1295-98A patent/SK129598A3/sk unknown
- 1998-09-22 AU AU86148/98A patent/AU748579B2/en not_active Ceased
- 1998-09-22 JP JP26835298A patent/JP4603104B2/ja not_active Expired - Fee Related
- 1998-09-22 NO NO984414A patent/NO984414L/no not_active Application Discontinuation
- 1998-09-22 HR HR19741873.2A patent/HRP980519A2/hr not_active Application Discontinuation
- 1998-09-22 BR BR9803969-5A patent/BR9803969A/pt not_active Application Discontinuation
- 1998-09-22 RU RU98117626/04A patent/RU2240326C2/ru not_active IP Right Cessation
- 1998-09-22 CN CN98119544A patent/CN1216767A/zh active Pending
- 1998-09-22 ZA ZA988668A patent/ZA988668B/xx unknown
- 1998-09-23 HU HU9802143A patent/HUP9802143A3/hu unknown
- 1998-09-23 US US09/158,772 patent/US6034238A/en not_active Expired - Lifetime
- 1998-09-23 PL PL328789A patent/PL191149B1/pl unknown
- 1998-09-23 KR KR1019980039351A patent/KR19990030046A/ko not_active Application Discontinuation
- 1998-09-25 TW TW087115671A patent/TW588051B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
HUP9802143A2 (hu)	1999-06-28
DE59814334D1 (de)	2009-03-12
TW588051B (en)	2004-05-21
RU2240326C2 (ru)	2004-11-20
US6034238A (en)	2000-03-07
EP0905139A2 (de)	1999-03-31
NZ331983A (en)	2000-02-28
AU8614898A (en)	1999-04-15
JPH11180960A (ja)	1999-07-06
TR199801870A2 (xx)	1999-04-21
SK129598A3 (en)	1999-04-13
ZA988668B (en)	1999-03-23
PL328789A1 (en)	1999-03-29
IL126278A0 (en)	1999-05-09
CA2247735A1 (en)	1999-03-23
HRP980519A2 (en)	1999-06-30
DE19741873A1 (de)	1999-03-25
NO984414L (no)	1999-03-24
MY134191A (en)	2007-11-30
BR9803969A (pt)	2000-05-02
ID20915A (id)	1999-03-25
CN1216767A (zh)	1999-05-19
HUP9802143A3 (en)	1999-11-29
AU748579B2 (en)	2002-06-06
KR19990030046A (ko)	1999-04-26
NO984414D0 (no)	1998-09-22
CZ303198A3 (cs)	1999-04-14
EP0905139A3 (de)	2002-12-18
ATE421524T1 (de)	2009-02-15
EP0905139B1 (de)	2009-01-21
JP4603104B2 (ja)	2010-12-22
PL191149B1 (pl)	2006-03-31

Publication	Publication Date	Title
HU9802143D0 (en)	1998-11-30	New heterocyclic compounds of 5 members in the ring, process for producing them and pharmaceutical compositions containing them
IL117848A0 (en)	1996-08-04	Novel compounds a process for their production and pharmacetical compositions containing same
IL101819A0 (en)	1992-12-30	Amidinophenylalanine derivatives,a process for the preparation thereof,use thereof and agents containing these as anticoagulants
IL110151A0 (en)	1994-10-07	Amide and urea derivatives and pharmaceutical compositions containing the same
AU673893B2 (en)	1996-11-28	New pyridothiadiazones, processes for their preparation and the pharmaceutical compositions which contain them
AU656466B2 (en)	1995-02-02	New benzimidazole compounds, a process for their preparation and pharmaceutical compositions containing them
ZA919030B (en)	1992-08-26	Compounds of n-benzoyl proline,process for their preparation and pharmaceutical compositions containing them
IL93598A0 (en)	1990-12-23	(3-(c16-c18)-alkanesulphinyl-and-sulphonyl-2-methoxy-methylpropyl)-(2-trimethyl-ammoniumethyl)phosphates,processes for the preparation thereof and pharmaceutical compositions containing them
CA2153549A1 (fr)	1996-01-13	Nouveau derive de benzothiadiazine, son procede de preparation et les compositions pharmeceutiques qui le contiennent
GR3023934T3 (en)	1997-09-30	New naphthalene amides and sulfonamides, process for their preparation and pharmaceutical compositions containing them
ZA944728B (en)	1995-07-13	alph -amino acid compounds a process for the preparation thereof and pharmaceutical compositions containing them
PL316870A1 (en)	1997-02-17	Derivatives of 5-heterocyclo 1,5-benzodiazepine
PL315052A1 (en)	1996-09-30	Condensed dihydropyridines, method of obtaining them, their application in producing pharmaceutic preparations and pharmaceutic preparations containing such compounds
ZA932359B (en)	1994-06-15	3-Aminochroman spiro compounds processes for preparing them and pharmaceutical compositions containing them
TW252979B (hu)	1995-08-01
HUT50787A (en)	1990-03-28	Process for producing pharmaceutical compositions comprising 4-aryl-4-piperidine-, pyrrolidine- or hexahydroazepincarbinol derivatives or heterocyclic analogs thereof as active ingredient and process for producing the new compounds
HK1004919A1 (en)	1998-12-11	New 17-hydroxyiminomethyl-5beta 14beta-androstane derivatives active on the cardiovascular system processes for their preparation and pharmaceutical compositions containing same
CA2137889A1 (fr)	1995-06-15	Nouveaux analogues de l'eburnane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
IL134194A0 (en)	2001-04-30	Streptogramines, their preparation and compositions containing them
AU5522794A (en)	1994-08-25	New angiopeptin cyclopeptide compounds, process for the preparation thereof, and pharmaceutical compositios containing them
AU6860794A (en)	1995-02-02	(Thia)cycloalkyl(b)indoles, process for preparing them and pharmaceutical compositions containing them
ES8505685A1 (es)	1985-06-01	Un procedimiento para preparar compuestos de espiro (2h-1,4-benzodioxepin-3(5h)4'-piperidina y -3'-pirrolidina)

Legal Events

Date	Code	Title	Description
2007-06-28	FD9A	Lapse of provisional protection due to non-payment of fees