HRP20100485T1 - Pripravci zasnovani na ksantoksilinu i njihova kozmetička upotreba - Google Patents
Pripravci zasnovani na ksantoksilinu i njihova kozmetička upotreba Download PDFInfo
- Publication number
- HRP20100485T1 HRP20100485T1 HR20100485T HRP20100485T HRP20100485T1 HR P20100485 T1 HRP20100485 T1 HR P20100485T1 HR 20100485 T HR20100485 T HR 20100485T HR P20100485 T HRP20100485 T HR P20100485T HR P20100485 T1 HRP20100485 T1 HR P20100485T1
- Authority
- HR
- Croatia
- Prior art keywords
- weight loss
- xanthoxylin
- plant extract
- cosmetic
- extract
- Prior art date
Links
- FBUBVLUPUDBFME-UHFFFAOYSA-N Xanthoxylin Chemical compound COC1=CC(O)=C(C(C)=O)C(OC)=C1 FBUBVLUPUDBFME-UHFFFAOYSA-N 0.000 title claims abstract 21
- 239000002537 cosmetic Substances 0.000 title claims 10
- 239000000203 mixture Substances 0.000 title claims 5
- 208000016261 weight loss Diseases 0.000 claims abstract 12
- 230000004580 weight loss Effects 0.000 claims abstract 12
- 239000000419 plant extract Substances 0.000 claims 7
- 239000000284 extract Substances 0.000 claims 5
- 241000221079 Euphorbia <genus> Species 0.000 claims 4
- 244000089698 Zanthoxylum simulans Species 0.000 claims 4
- 239000000499 gel Substances 0.000 claims 4
- 238000011200 topical administration Methods 0.000 claims 4
- 238000000034 method Methods 0.000 claims 3
- 235000003107 Artemisia maritima Nutrition 0.000 claims 2
- 240000008118 Artemisia maritima Species 0.000 claims 2
- 240000000572 Blumea balsamifera Species 0.000 claims 2
- 208000035484 Cellulite Diseases 0.000 claims 2
- 241001448862 Croton Species 0.000 claims 2
- 241000196324 Embryophyta Species 0.000 claims 2
- 241000221017 Euphorbiaceae Species 0.000 claims 2
- OHCQJHSOBUTRHG-KGGHGJDLSA-N FORSKOLIN Chemical compound O=C([C@@]12O)C[C@](C)(C=C)O[C@]1(C)[C@@H](OC(=O)C)[C@@H](O)[C@@H]1[C@]2(C)[C@@H](O)CCC1(C)C OHCQJHSOBUTRHG-KGGHGJDLSA-N 0.000 claims 2
- 241001300745 Hippomane mancinella Species 0.000 claims 2
- 241000012923 Melicope borbonica Species 0.000 claims 2
- 206010049752 Peau d'orange Diseases 0.000 claims 2
- 241000783088 Phebalium filifolium Species 0.000 claims 2
- 241000783091 Phebalium tuberculosum Species 0.000 claims 2
- 241001093501 Rutaceae Species 0.000 claims 2
- 244000057114 Sapium sebiferum Species 0.000 claims 2
- 235000005128 Sapium sebiferum Nutrition 0.000 claims 2
- 241000949456 Zanthoxylum Species 0.000 claims 2
- 244000294617 Zanthoxylum alatum Species 0.000 claims 2
- 241000189398 Zanthoxylum rhoifolium Species 0.000 claims 2
- 210000000577 adipose tissue Anatomy 0.000 claims 2
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 2
- 230000036232 cellulite Effects 0.000 claims 2
- 239000006071 cream Substances 0.000 claims 2
- 239000006210 lotion Substances 0.000 claims 2
- 239000008267 milk Substances 0.000 claims 2
- 210000004080 milk Anatomy 0.000 claims 2
- 235000013336 milk Nutrition 0.000 claims 2
- 239000002674 ointment Substances 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 239000007921 spray Substances 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- 239000003826 tablet Substances 0.000 claims 2
- FDHNLHLOJLLXDH-JIYHLSBYSA-N (e)-3-(3-hydroxy-4-methoxyphenyl)-1-[2-hydroxy-6-methoxy-4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-[[(2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxyphenyl]prop-2-en-1-one Chemical compound C1=C(O)C(OC)=CC=C1\C=C\C(=O)C(C(=C1)OC)=C(O)C=C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]2[C@@H]([C@H](O)[C@@H](O)[C@H](C)O2)O)O1 FDHNLHLOJLLXDH-JIYHLSBYSA-N 0.000 claims 1
- 235000005320 Coleus barbatus Nutrition 0.000 claims 1
- SUZLHDUTVMZSEV-UHFFFAOYSA-N Deoxycoleonol Natural products C12C(=O)CC(C)(C=C)OC2(C)C(OC(=O)C)C(O)C2C1(C)C(O)CCC2(C)C SUZLHDUTVMZSEV-UHFFFAOYSA-N 0.000 claims 1
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 claims 1
- 244000141359 Malus pumila Species 0.000 claims 1
- 235000011430 Malus pumila Nutrition 0.000 claims 1
- 235000015103 Malus silvestris Nutrition 0.000 claims 1
- 240000003444 Paullinia cupana Species 0.000 claims 1
- 235000000556 Paullinia cupana Nutrition 0.000 claims 1
- IOUVKUPGCMBWBT-UHFFFAOYSA-N Phlorizine Chemical compound OC1C(O)C(O)C(CO)OC1OC1=CC(O)=CC(O)=C1C(=O)CCC1=CC=C(O)C=C1 IOUVKUPGCMBWBT-UHFFFAOYSA-N 0.000 claims 1
- 241000243177 Pilosella officinarum Species 0.000 claims 1
- 241000131459 Plectranthus barbatus Species 0.000 claims 1
- 244000131415 Zanthoxylum piperitum Species 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 229960001948 caffeine Drugs 0.000 claims 1
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 claims 1
- OHCQJHSOBUTRHG-UHFFFAOYSA-N colforsin Natural products OC12C(=O)CC(C)(C=C)OC1(C)C(OC(=O)C)C(O)C1C2(C)C(O)CCC1(C)C OHCQJHSOBUTRHG-UHFFFAOYSA-N 0.000 claims 1
- 239000003581 cosmetic carrier Substances 0.000 claims 1
- 229940076640 hesperidin methylchalcone Drugs 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/06—Preparations for care of the skin for countering cellulitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/92—Oral administration
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Mycology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Upotreba ksantoksilina, naznačena time da je za tretman mršavljenja. Patent sadrži još 17 patentnih zahtjeva.
Claims (18)
1. Upotreba ksantoksilina, naznačena time da je za tretman mršavljenja.
2. Upotreba ksantoksilina, naznačena time da je za prevenciju i tretman suviška masnog tkiva i celulita.
3. Upotreba prema patentnom zahtjevu 1 ili 2, naznačena time da je ksantoksilin dobiven iz biljnog ekstrakta.
4. Upotreba prema patentnom zahtjevu 3, naznačena time da biljni ekstrakt potječe iz biljaka iz porodice Rutaceae: Melicope borbonica, Phebalium tuberculosum, Phebalium filifolium, te sljedeći iz roda Zanthoxylum: Z. rhoifolium, Z. armatum, Z. bungeanum, Z. piperitum; porodice Euphorbiaceae: Croton nepetaefolium, Hippomane mancinella, Sapium sebiferum, Sebastiana schottiana, Euphorbia quinquecostata, Euphorbia fidjiana te iz Blumea balsamifera te Artemisia brevifolia.
5. Upotreba prema patentnom zahtjevu 3, naznačena time da biljni ekstrakt potječe iz Zanthoxylum bungeanum.
6. Upotreba prema patentnom zahtjevu 3, naznačena time da je maseni udio ksantoksilina u rečenom ekstraktu između uključivo 0.1 i 30 g po 100 g suhog ekstrakta.
7. Upotreba prema bilo kojem od patentnih zahtjeva 3 do 6, naznačena time da je biljni ekstrakt obogaćen ksantoksilinom, te da je maseni udio ksantoksilina u rečenom obogaćenom ekstraktu sadrži veći od 30 g po 100 g suhog ekstrakta.
8. Kozmetički pripravak za mršavljenje, naznačen time da sadrži ksantoksilin i najmanje jednu aktivnu tvar za mršavljenje skupa s pogodnim kozmetičkim nosačem.
9. Kozmetički pripravak za mršavljenje prema patentnom zahtjevu 8, naznačen time da je drugi aktivni sastojak za mršavljenje odabran iz sljedeće skupine: kafein i njegove soli, floridizin, forskolin, hesperidin metil kalkon, guarana, mate, ekstrakti Hieracium pilosella, ruskusa, bršljana, grana stabla jabuke i Coleus forskohlii, korištenih samih ili u smjesi.
10. Kozmetički pripravak za mršavljenje prema bilo kojem od patentnih zahtjeva 8 do 9, naznačen time da je ksantoksilin dobiven iz biljnog ekstrakta.
11. Kozmetički pripravak za mršavljenje prema patentom zahtjevu 10, naznačen time da biljni ekstrakt potječe iz biljaka iz Rutaceae: Melicope borbonica, Phebalium tuberculosum, Phebalium filifolium, te sljedeći iz roda Zanthoxylum: Z. rhoifolium, Z. armatum, Z. bungeanum, Z. piperitum; porodice Euphorbiaceae: Croton nepetaefolium, Hippomane mancinella, Sapium sebiferum, Sebastiana schottiana, Euphorbia quinquecostata, Euphorbia fidjiana te iz Blumea balsamifera te Artemisia brevifolia.
12. Kozmetički pripravak za mršavljenje prema patentnom zahtjevu 10, naznačen time da biljni ekstrakt potječe iz Zanthoxylum bungeanum.
13. Kozmetički pripravak za mršavljenje prema bilo kojem od patentnih zahtjeva 8 do 12, naznačen time da je obliku za oralno ili topičko davanje.
14. Kozmetički pripravak za mršavljenje prema patentnom zahtjevu 13, naznačen time da je oblik za topičko davanje odabran iz sljedeće skupine: gel, sprej, krema, kremasti gel, mast, mlijeko ili losion.
15. Kozmetički pripravak za mršavljenje prema patentnom zahtjevu 13, naznačen time da je oblik za oralno davanje odabran iz sljedeće skupine: tablete, kapsule i prašci za suspenzije koje se piju.
16. Metoda kozmetičkog tretmana kože za sprječavanje ili smanjivanje suviška masnog tkiva i celulita, naznačen time da obuhvaća topičko davanje ksantoksilina na zone kože koji trebaju takav tretman ili oralno.
17. Metoda prema patentnom zahtjevu 16, naznačena time da je oblik za topičko davanje odabran iz sljedeće skupine: gel, sprej, krema, kremasti gel, mast, mlijeko ili losion.
18. Metoda prema patentnom zahtjevu 16, naznačen time da je oblik za oralno davanje odabran iz sljedeće skupine: tablete, kapsule i prašci za suspenzije koje se piju.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0608129A FR2905854B1 (fr) | 2006-09-15 | 2006-09-15 | Composition a base de xanthoxyline et son utilisation en cosmetique |
| PCT/FR2007/001467 WO2008031940A2 (fr) | 2006-09-15 | 2007-09-11 | Composition a base de xanthoxyline et son utilisation en cosmetique. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20100485T1 true HRP20100485T1 (hr) | 2010-10-31 |
Family
ID=37930368
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20100485T HRP20100485T1 (hr) | 2006-09-15 | 2010-09-03 | Pripravci zasnovani na ksantoksilinu i njihova kozmetička upotreba |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20100048729A1 (hr) |
| EP (1) | EP2066408B1 (hr) |
| JP (1) | JP2010503643A (hr) |
| AR (1) | AR062855A1 (hr) |
| AT (1) | ATE473784T1 (hr) |
| BR (1) | BRPI0716754A8 (hr) |
| CA (1) | CA2663387C (hr) |
| DE (1) | DE602007007792D1 (hr) |
| ES (1) | ES2345407T3 (hr) |
| FR (1) | FR2905854B1 (hr) |
| HR (1) | HRP20100485T1 (hr) |
| MX (1) | MX2009002224A (hr) |
| PL (1) | PL2066408T3 (hr) |
| PT (1) | PT2066408E (hr) |
| TW (1) | TWI382856B (hr) |
| WO (1) | WO2008031940A2 (hr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010180166A (ja) * | 2009-02-06 | 2010-08-19 | Pola Chem Ind Inc | 痩身用の組成物 |
| FR2986709B1 (fr) * | 2012-02-09 | 2015-09-25 | Nuxe Lab | Composition a base d'extrait d'ecorce de pommier utilisable en cosmetique |
| US20140120190A1 (en) * | 2012-10-20 | 2014-05-01 | Dong-Qing WEI | Methods of preparing prickly-ash peel extracts and cosmetic compositions incorporating prickly-ash peel extracts |
| WO2014092684A2 (en) * | 2012-12-11 | 2014-06-19 | Avon Products, Inc. | Use of melicope extracts to improve conditions caused by excess lipids |
| DE102013213596A1 (de) | 2013-07-11 | 2015-01-15 | Henkel Ag & Co. Kgaa | Mund- und Zahnpflege- und -reinigungsmittel zur Zahnfleischvitalisierung |
| FR3011179B1 (fr) * | 2013-10-01 | 2017-01-06 | Laboratoires De Biologie Vegetale Yves Rocher | Utilisation d'un extrait d'artemisia orientalis dans une composition cosmetique amincissante |
| FR3011180B1 (fr) * | 2013-10-01 | 2017-01-06 | Laboratoires De Biologie Vegetale Yves Rocher | Utilisation d'un extrait d'artemisia montana dans une composition cosmetique amincissante |
| EP3062767A4 (en) * | 2013-10-30 | 2018-01-03 | Unigen, Inc. | Skin care compositions and methods of use thereof |
| CN110575413A (zh) * | 2019-10-24 | 2019-12-17 | 山东花物堂生物科技有限公司 | 一种花椒提取物的制备方法及其在化妆品的应用 |
| KR20220088874A (ko) * | 2019-10-30 | 2022-06-28 | 토요 슈가 리파이닝 컴퍼니 리미티드 | 셀룰라이트 개선용 피부 외용제 및 셀룰라이트 개선 방법 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6124511A (ja) * | 1984-07-13 | 1986-02-03 | Pola Chem Ind Inc | リツプ化粧料 |
| JP3452986B2 (ja) * | 1994-09-13 | 2003-10-06 | 花王株式会社 | 脂肪分解促進剤 |
| US5523090A (en) * | 1995-02-24 | 1996-06-04 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Skin treatment composition |
| IL122591A0 (en) * | 1997-12-14 | 1998-06-15 | Arad Dorit | Pharmaceutical compositions comprising cystein protease inhibitors |
| ITMI981542A1 (it) * | 1998-07-07 | 2000-01-07 | Indena Spa | Estratti di zanthoxylum bungeanum e loro formulazioni farmaceutiche e cosmetiche |
| JP3537671B2 (ja) * | 1998-08-21 | 2004-06-14 | カネボウ株式会社 | 脂肪分解促進剤及び痩身用皮膚化粧料 |
| FR2807317B1 (fr) * | 2000-04-10 | 2002-08-16 | Indena Sa | Compositions de soin capillaire |
| JP2003113104A (ja) * | 2001-10-01 | 2003-04-18 | Pola Chem Ind Inc | 熱産生タンパク質発現促進剤及びそれを含有する組成物 |
| JP2004035425A (ja) * | 2002-07-01 | 2004-02-05 | Naris Cosmetics Co Ltd | むくみ改善剤 |
| JP2004051486A (ja) * | 2002-07-16 | 2004-02-19 | Pola Chem Ind Inc | 熱産生交感神経活性化剤 |
| JP2006096666A (ja) * | 2002-10-31 | 2006-04-13 | Kaneka Corp | 選択的ヒトβ３アドレナリン受容体アゴニスト剤 |
| JP2007186515A (ja) * | 2003-05-02 | 2007-07-26 | Takara Bio Inc | 治療剤 |
| ITMI20032286A1 (it) * | 2003-11-24 | 2005-05-25 | Indena Spa | Composizioni per il trattamento di dermatiti atopiche di stati allergici cutanei e dell'acne |
| US20050271608A1 (en) * | 2004-06-05 | 2005-12-08 | Gupta Shyam K | Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives |
-
2006
- 2006-09-15 FR FR0608129A patent/FR2905854B1/fr not_active Expired - Fee Related
-
2007
- 2007-09-11 MX MX2009002224A patent/MX2009002224A/es active IP Right Grant
- 2007-09-11 EP EP07823496A patent/EP2066408B1/fr active Active
- 2007-09-11 AT AT07823496T patent/ATE473784T1/de not_active IP Right Cessation
- 2007-09-11 WO PCT/FR2007/001467 patent/WO2008031940A2/fr active Application Filing
- 2007-09-11 US US12/310,960 patent/US20100048729A1/en not_active Abandoned
- 2007-09-11 JP JP2009527854A patent/JP2010503643A/ja active Pending
- 2007-09-11 PL PL07823496T patent/PL2066408T3/pl unknown
- 2007-09-11 PT PT07823496T patent/PT2066408E/pt unknown
- 2007-09-11 CA CA2663387A patent/CA2663387C/fr active Active
- 2007-09-11 ES ES07823496T patent/ES2345407T3/es active Active
- 2007-09-11 BR BRPI0716754A patent/BRPI0716754A8/pt not_active Application Discontinuation
- 2007-09-11 DE DE602007007792T patent/DE602007007792D1/de active Active
- 2007-09-14 AR ARP070104085A patent/AR062855A1/es unknown
- 2007-09-14 TW TW096134341A patent/TWI382856B/zh active
-
2010
- 2010-09-03 HR HR20100485T patent/HRP20100485T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR062855A1 (es) | 2008-12-10 |
| BRPI0716754A2 (pt) | 2013-09-17 |
| PT2066408E (pt) | 2010-09-29 |
| JP2010503643A (ja) | 2010-02-04 |
| WO2008031940A3 (fr) | 2008-05-22 |
| EP2066408B1 (fr) | 2010-07-14 |
| FR2905854A1 (fr) | 2008-03-21 |
| TW200835522A (en) | 2008-09-01 |
| FR2905854B1 (fr) | 2010-07-30 |
| MX2009002224A (es) | 2009-04-30 |
| PL2066408T3 (pl) | 2010-12-31 |
| WO2008031940A2 (fr) | 2008-03-20 |
| DE602007007792D1 (de) | 2010-08-26 |
| ATE473784T1 (de) | 2010-07-15 |
| CA2663387A1 (fr) | 2008-03-20 |
| US20100048729A1 (en) | 2010-02-25 |
| TWI382856B (zh) | 2013-01-21 |
| BRPI0716754A8 (pt) | 2017-09-12 |
| CA2663387C (fr) | 2015-10-06 |
| EP2066408A2 (fr) | 2009-06-10 |
| ES2345407T3 (es) | 2010-09-22 |
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