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HK1251550A1 - 作為hdac抑制劑的3-芳基-4-酰氨基-二環[4，5，0]異羥肟酸 - Google Patents

作為hdac抑制劑的3-芳基-4-酰氨基-二環[4，5，0]異羥肟酸

Info

Publication number
HK1251550A1
HK1251550A1 HK18110821.4A HK18110821A HK1251550A1 HK 1251550 A1 HK1251550 A1 HK 1251550A1 HK 18110821 A HK18110821 A HK 18110821A HK 1251550 A1 HK1251550 A1 HK 1251550A1
Authority
HK
Hong Kong
Prior art keywords
amido
bicyclic
aryl
hdac inhibitors
hydroxamic acids
Prior art date
Application number
HK18110821.4A
Other languages
English (en)
Inventor
X．鄭
P.Y.恩格
B．韓
J．R．托馬森
M．M．扎布洛茨基
C．劉
H．戴維斯
A．魯德尼特斯卡亞
小大衛．R．蘭西亞
D．S．米蘭
M．W．馬丁
Original Assignee
福馬治療股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 福馬治療股份有限公司 filed Critical 福馬治療股份有限公司
Publication of HK1251550A1 publication Critical patent/HK1251550A1/zh

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    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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HK18110821.4A 2015-02-02 2018-08-22 作為hdac抑制劑的3-芳基-4-酰氨基-二環[4，5，0]異羥肟酸 HK1251550A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562110716P 2015-02-02 2015-02-02
US201562205438P 2015-08-14 2015-08-14
PCT/US2016/016200 WO2016126724A1 (en) 2015-02-02 2016-02-02 3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as hdac inhibitors

Publications (1)

Publication Number Publication Date
HK1251550A1 true HK1251550A1 (zh) 2019-02-01

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
HK18110821.4A HK1251550A1 (zh) 2015-02-02 2018-08-22 作為hdac抑制劑的3-芳基-4-酰氨基-二環[4，5，0]異羥肟酸
HK18112615.0A HK1253322A1 (zh) 2015-02-02 2018-10-02 作為hdac抑制劑的3-烷基-4-酰氨基-雙環[4，5，0]異羥肟酸

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HK18112615.0A HK1253322A1 (zh) 2015-02-02 2018-10-02 作為hdac抑制劑的3-烷基-4-酰氨基-雙環[4，5，0]異羥肟酸

Country Status (27)

Country Link
US (32) US10112915B2 (zh)
EP (3) EP3292116B8 (zh)
JP (1) JP6668362B2 (zh)
KR (1) KR102633628B1 (zh)
CN (3) CN107801396B (zh)
AU (4) AU2016215432B2 (zh)
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