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HK1116803A1 - Novel anti-plgf antibody - Google Patents

Novel anti-plgf antibody

Info

Publication number
HK1116803A1
HK1116803A1 HK08102805.3A HK08102805A HK1116803A1 HK 1116803 A1 HK1116803 A1 HK 1116803A1 HK 08102805 A HK08102805 A HK 08102805A HK 1116803 A1 HK1116803 A1 HK 1116803A1
Authority
HK
Hong Kong
Prior art keywords
novel anti
plgf antibody
fragments
plgf
antibody
Prior art date
Application number
HK08102805.3A
Other languages
English (en)
Inventor
Jean-Marie Stassen
Peter Carmeliet
Desire Collen
Original Assignee
Thrombogenics Nv
Life Sciences Res Partners
Vlaams Interuniv Inst Biotech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thrombogenics Nv, Life Sciences Res Partners, Vlaams Interuniv Inst Biotech filed Critical Thrombogenics Nv
Publication of HK1116803A1 publication Critical patent/HK1116803A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mycology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK08102805.3A 2005-03-24 2008-03-11 Novel anti-plgf antibody HK1116803A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66476805P 2005-03-24 2005-03-24
PCT/BE2006/000023 WO2006099698A2 (en) 2005-03-24 2006-03-24 Novel anti-plgf antibody

Publications (1)

Publication Number Publication Date
HK1116803A1 true HK1116803A1 (en) 2009-01-02

Family

ID=36928446

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08102805.3A HK1116803A1 (en) 2005-03-24 2008-03-11 Novel anti-plgf antibody

Country Status (27)

Country Link
US (3) US7875704B2 (ko)
EP (2) EP2447281B1 (ko)
JP (2) JP5164829B2 (ko)
KR (1) KR101314014B1 (ko)
CN (1) CN101184776B (ko)
AT (1) ATE549358T1 (ko)
AU (2) AU2006227571B8 (ko)
BR (1) BRPI0609151B8 (ko)
CA (1) CA2601267C (ko)
CY (1) CY1113224T1 (ko)
DK (1) DK1869085T3 (ko)
EA (1) EA013970B1 (ko)
ES (2) ES2384110T3 (ko)
HK (1) HK1116803A1 (ko)
HR (1) HRP20120477T1 (ko)
IL (1) IL185754A (ko)
ME (1) ME01446B (ko)
MX (1) MX2007011735A (ko)
NO (1) NO341877B1 (ko)
NZ (1) NZ561763A (ko)
PL (1) PL1869085T3 (ko)
PT (1) PT1869085E (ko)
RS (1) RS52372B (ko)
SI (1) SI1869085T1 (ko)
UA (1) UA94707C2 (ko)
WO (1) WO2006099698A2 (ko)
ZA (1) ZA200707258B (ko)

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CN104930353B (zh) * 2015-07-10 2017-08-15 浙江大学 一种城市供水管网的调压减漏评估系统
US20190031762A1 (en) 2016-03-10 2019-01-31 Thrombogenics Nv Posterior ocular fibrosis inhibition by antagonizing placental growth factor
EP3471767A4 (en) 2016-06-15 2020-01-15 Icahn School of Medicine at Mount Sinai INFLUENZA VIRUS HEMAGGLUTININS AND USES THEREOF
WO2018187706A2 (en) 2017-04-07 2018-10-11 Icahn School Of Medicine At Mount Sinai Anti-influenza b virus neuraminidase antibodies and uses thereof
CN109134650A (zh) * 2018-09-10 2019-01-04 宁波奥丞生物科技有限公司 抗人plgf单克隆抗体的制备方法
US20220228116A1 (en) 2019-05-28 2022-07-21 Vib Vzw Cd8+ t-cells lacking plexins and their application in cancer treatment
WO2020239945A1 (en) 2019-05-28 2020-12-03 Vib Vzw Cancer treatment by targeting plexins in the immune compartment
WO2020260595A1 (en) 2019-06-26 2020-12-30 Oncurious Nv Combination treatment of medulloblastoma using a placental growth factor inhibitor and a chemotherapeutic agent
EP3936868A1 (en) 2020-07-10 2022-01-12 Charité - Universitätsmedizin Berlin A ratio between plgf and sflt1 is predictive for neural invasion in patients suffering from pancreatic cancer
WO2022063957A1 (en) 2020-09-24 2022-03-31 Vib Vzw Biomarker for anti-tumor therapy
CN112358546B (zh) * 2020-11-10 2022-04-01 宁波奥丞生物科技有限公司 杂交瘤细胞株9c1、plgf-1单克隆抗体及其应用
WO2022099465A1 (zh) * 2020-11-10 2022-05-19 宁波奥丞生物科技有限公司 杂交瘤细胞株9c1、plgf-1单克隆抗体及其制备方法和应用
JP2023554520A (ja) 2020-12-22 2023-12-27 コビオレス エヌヴイ テトラペプチド部分を含む化合物
CN113999310A (zh) * 2020-12-30 2022-02-01 江苏普若维生物技术有限责任公司 一种plgf单克隆抗体、试剂盒、其制备方法和应用
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Also Published As

Publication number Publication date
KR20080016794A (ko) 2008-02-22
CY1113224T1 (el) 2016-04-13
MX2007011735A (es) 2008-03-14
NO20074563L (no) 2007-12-18
AU2011201340A1 (en) 2011-04-14
SI1869085T1 (sl) 2012-07-31
UA94707C2 (en) 2011-06-10
RS52372B (en) 2012-12-31
ZA200707258B (en) 2008-06-25
KR101314014B1 (ko) 2013-10-02
WO2006099698A2 (en) 2006-09-28
IL185754A0 (en) 2008-01-06
BRPI0609151B8 (pt) 2021-05-25
AU2006227571B8 (en) 2011-01-27
EP2447281A1 (en) 2012-05-02
ES2384110T3 (es) 2012-06-29
AU2006227571B2 (en) 2010-12-23
CN101184776A (zh) 2008-05-21
BRPI0609151B1 (pt) 2020-01-21
JP2008532557A (ja) 2008-08-21
AU2006227571A1 (en) 2006-09-28
US20110123525A1 (en) 2011-05-26
EA200702064A1 (ru) 2008-02-28
NO341877B1 (no) 2018-02-12
NZ561763A (en) 2009-02-28
IL185754A (en) 2013-02-28
HRP20120477T1 (hr) 2012-07-31
WO2006099698A3 (en) 2006-11-30
ATE549358T1 (de) 2012-03-15
CA2601267C (en) 2014-02-18
ES2565481T3 (es) 2016-04-05
EP1869085A2 (en) 2007-12-26
BRPI0609151A2 (pt) 2010-02-17
PL1869085T3 (pl) 2012-09-28
EP1869085B1 (en) 2012-03-14
JP2012136522A (ja) 2012-07-19
US8758748B2 (en) 2014-06-24
CA2601267A1 (en) 2006-09-28
US9085617B2 (en) 2015-07-21
AU2011201340B2 (en) 2012-02-23
US7875704B2 (en) 2011-01-25
EP2447281B1 (en) 2015-12-16
PT1869085E (pt) 2012-06-01
ME01446B (me) 2013-12-20
US20080193455A1 (en) 2008-08-14
JP5164829B2 (ja) 2013-03-21
DK1869085T3 (da) 2012-06-18
US20140178397A1 (en) 2014-06-26
CN101184776B (zh) 2013-04-24
EA013970B1 (ru) 2010-08-30

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