[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

HK1105785A1 - Mammalian-type glycosylation in plants - Google Patents

Mammalian-type glycosylation in plants

Info

Publication number
HK1105785A1
HK1105785A1 HK07111001.7A HK07111001A HK1105785A1 HK 1105785 A1 HK1105785 A1 HK 1105785A1 HK 07111001 A HK07111001 A HK 07111001A HK 1105785 A1 HK1105785 A1 HK 1105785A1
Authority
HK
Hong Kong
Prior art keywords
plants
mammalian
normally
present
plant
Prior art date
Application number
HK07111001.7A
Other languages
English (en)
Inventor
Hendrikus Antonius Cornelis Bakker
Hendrik Jan Bosch
Original Assignee
Stichting Dienst Landbouwkundi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stichting Dienst Landbouwkundi filed Critical Stichting Dienst Landbouwkundi
Publication of HK1105785A1 publication Critical patent/HK1105785A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
HK07111001.7A 1999-10-26 2007-10-11 Mammalian-type glycosylation in plants HK1105785A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99203524 1999-10-26
EP99203523 1999-10-26

Publications (1)

Publication Number Publication Date
HK1105785A1 true HK1105785A1 (en) 2008-02-22

Family

ID=26153384

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07111001.7A HK1105785A1 (en) 1999-10-26 2007-10-11 Mammalian-type glycosylation in plants

Country Status (17)

Country Link
US (3) US7781647B2 (xx)
EP (3) EP1228231B1 (xx)
JP (1) JP4890712B2 (xx)
AT (2) ATE478150T1 (xx)
AU (1) AU1738401A (xx)
BR (1) BRPI0015031B1 (xx)
CA (2) CA2925231A1 (xx)
DE (2) DE60035285T2 (xx)
DK (2) DK1228231T3 (xx)
ES (1) ES2288882T3 (xx)
HK (1) HK1105785A1 (xx)
IL (6) IL149271A0 (xx)
MX (1) MXPA02004142A (xx)
NZ (1) NZ518532A (xx)
PT (2) PT1228231E (xx)
TR (1) TR200201121T2 (xx)
WO (1) WO2001031045A1 (xx)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL143641A0 (en) 1998-12-09 2002-04-21 A method for manufacturing glycoproteins having human-type glycosylation
CA2388432A1 (en) * 1999-10-21 2001-04-26 Monsanto Company Post-translational modification of recombinant proteins produced in plants
ATE478150T1 (de) 1999-10-26 2010-09-15 Stichting Dienst Landbouwkundi Säugetierartige glykosylierung in pflanzen
JP5623683B2 (ja) * 2000-03-22 2014-11-12 フィトン ホールディングス，リミティド ライアビリティ カンパニー 動物型糖鎖付加機能をもつ植物細胞
FR2807767B1 (fr) 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
US7632983B2 (en) 2000-07-31 2009-12-15 Biolex Therapeutics, Inc. Expression of monoclonal antibodies in duckweed
US8022270B2 (en) 2000-07-31 2011-09-20 Biolex Therapeutics, Inc. Expression of biologically active polypeptides in duckweed
CN100385006C (zh) * 2001-01-19 2008-04-30 陶氏化学公司 利用植物细胞分泌性生产具有人型糖链的糖蛋白的方法
CN101781635A (zh) * 2001-03-06 2010-07-21 陶氏化学公司 具有动物型糖链加成功能的植物细胞
GB2377446B (en) * 2001-07-13 2005-06-29 Lars Erik Berglund Expression of cobalamin binding proteins in transgenic plants
EP1485492B1 (en) * 2002-03-19 2011-12-21 Stichting Dienst Landbouwkundig Onderzoek Gntiii (udp-n-acetylglucosamine:beta-d mannoside beta(1,4)-n-acetylglucosaminyltransferase iii) expression in plants
AU2008202355B2 (en) * 2002-03-19 2011-04-07 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
CA2478297C (en) * 2002-03-19 2013-05-14 Plant Research International B.V. Optimizing glycan processing in plants
AU2013205260B2 (en) * 2002-03-19 2016-02-18 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
AR042145A1 (es) * 2002-11-27 2005-06-08 Dow Agrociences Llc Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
SG179292A1 (en) * 2003-01-22 2012-04-27 Roche Glycart Ag Fusion constructs and use of same to produce antibodies with increased fc receptor binding affinity and effector function
EP1536229A1 (en) * 2003-11-26 2005-06-01 Plant Research International B.V. Method to identify a biomolecular profile
AU2005233387B2 (en) * 2004-04-15 2011-05-26 Glycofi, Inc. Production of galactosylated glycoproteins in lower eukaryotes
US8617575B2 (en) 2004-05-31 2013-12-31 Kitasato Daiichi Sankyo Vaccine Co., Ltd. Methods for conferring immunity against protozoans in an animal
CA2570566A1 (en) * 2004-06-25 2006-01-12 Altor Bioscience Corporation Production of tissue factor in plants
JP2006288210A (ja) * 2005-04-05 2006-10-26 National Institute Of Advanced Industrial & Technology 糖転移酵素遺伝子の導入による生体内糖鎖伸長の技術
DE602006015195D1 (de) * 2005-07-12 2010-08-12 Greenovation Biotech Gmbh Verbesserungen der proteinproduktion oder in zusammenhang damit
JP2009523432A (ja) 2006-01-17 2009-06-25 バイオレックス セラピュティックス インク 植物中でのｎ−グリカンのヒト化及び最適化のための組成物及び方法
EP2224009B1 (en) 2006-02-09 2012-10-31 Medicago Inc. Synthesis of sialic acid in plants
EP1878747A1 (en) 2006-07-11 2008-01-16 greenovation Biotech GmbH Glyco-engineered antibodies
BRPI0810443A2 (pt) * 2007-04-17 2016-09-27 Plant Res Int Bv glicosilação do tipo em mamífero em plantas através da expressão de glicosiltransferases de não mamíferos
AU2013203379B2 (en) * 2007-04-17 2016-01-21 Stichting Dienst Landbouwkundig Onderzoek Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases
WO2008141806A1 (en) * 2007-05-21 2008-11-27 Bayer Bioscience N.V. Methods and means for producing glycoproteins with altered glycosylation pattern in higher plants
BRPI0812538B1 (pt) * 2007-06-15 2021-03-16 Medicago Inc. processo para a síntese de uma proteína de interesse com fucosilação e xilosilação reduzidas, ácido nucleico, e proteína híbrida gnt1-galt
AU2009270404B2 (en) 2008-07-18 2015-01-29 Medicago Inc. New influenza virus immunizing epitope
US8232073B2 (en) 2009-01-02 2012-07-31 Zacharon Pharmaceuticals, Inc. Quantification of non-reducing end glycan residual compounds
US9029530B2 (en) 2009-01-02 2015-05-12 Biomarin Pharmaceutical Inc. Detection of oligosaccharides
US8809009B2 (en) 2009-01-02 2014-08-19 Biomarin Pharmaceutical Inc. Methods of diagnosing a disease and methods of monitoring treatment of a disease by quantifying a non-reducing end glycan residual compound and comparing to a second biomarker
WO2010111713A2 (en) * 2009-03-27 2010-09-30 Zacharon Pharmaceuticals, Inc. N-linked glycan biosynthesis modulators
WO2013019625A2 (en) 2011-07-29 2013-02-07 The University Of Wyoming Methods of using a bacterial glcnac-6-p 2'-epimerase to promote sialylation of glycoconjugates
US9816107B2 (en) 2011-07-29 2017-11-14 The University Of Wyoming Transgenic insect cells comprising a bacterial GlcNAc-6-P 2′-epimerase
US9546219B2 (en) 2012-02-08 2017-01-17 North Carolina State University Treatment of allergic diseases with recombinant antibodies
US20140115728A1 (en) 2012-10-24 2014-04-24 A. Joseph Tector Double knockout (gt/cmah-ko) pigs, organs and tissues
CA3041717A1 (en) 2016-11-09 2018-05-17 North Carolina State University Treatment of allergic diseases with chimeric protein
EP3548612A4 (en) 2016-12-01 2020-04-15 Plantform Corporation TRANSGENIC PLANT WITH REDUCED FUCOSYL TRANSFERASE AND XYLOSYL TRANSFERASE ACTIVITY
JP6934666B2 (ja) * 2018-01-18 2021-09-15 国立研究開発法人産業技術総合研究所 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法
WO2019183437A1 (en) 2018-03-23 2019-09-26 North Carolina State University Methods and compositions for antibody to high affinity receptor for ige
USD1034550S1 (en) * 2022-12-19 2024-07-09 Shenzhen Xunweijia Technology Development Co., Ltd. Microphone
USD1034549S1 (en) * 2022-12-19 2024-07-09 Shenzhen Xunweijia Technology Development Co., Ltd. Microphone

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5455790A (en) 1977-10-05 1979-05-04 Tomoyuki Tajima Production of erythropoetin
JPS5616496A (en) 1979-07-20 1981-02-17 Sumitomo Chem Co Ltd Recovery of erythropoietin
JPS5653696A (en) 1979-10-09 1981-05-13 Ajinomoto Co Inc Isolation of erythropoietin by adsorption
JPS56108798A (en) 1980-02-01 1981-08-28 Green Cross Corp:The Purification of erythropoietin
JPS57149228A (en) 1981-03-11 1982-09-14 Ajinomoto Co Inc Novel erythropoietin and its preparation
JPS57169424A (en) 1981-04-10 1982-10-19 Toyo Shinyaku Kk Preparation of erythropoietin
US4956282A (en) * 1985-07-29 1990-09-11 Calgene, Inc. Mammalian peptide expression in plant cells
US5179198A (en) 1988-07-11 1993-01-12 Hidechika Okada Glycoprotein and gene coding therefor
US5959177A (en) * 1989-10-27 1999-09-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
US5202422A (en) * 1989-10-27 1993-04-13 The Scripps Research Institute Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins and method of their use
WO1991016449A1 (en) * 1990-04-16 1991-10-31 The Trustees Of The University Of Pennsylvania Saccharide compositions, methods and apparatus for their synthesis
ES2164050T3 (es) 1991-04-18 2002-02-16 Toray Industries Preparacion de compuestos de interleuquina-6.
US5874271A (en) * 1992-08-21 1999-02-23 Takara Shuzo Co., Ltd. Human glycosyltransferase gene, compounds and method for inhibiting cancerous metastasis
WO1994012646A1 (en) 1992-11-27 1994-06-09 Ciba-Geigy Ag Proteins having glycosyltransferase activity
JPH09503905A (ja) * 1993-07-15 1997-04-22 ネオゼ ファーマシューティカルス 糖組成物の合成方法
EP0737745A4 (en) 1993-12-24 1999-06-16 Rikagaku Kenkyusho NOVEL SUGAR CHAIN SYNTHETASE, AND PROCESS FOR PRODUCING THE SAME
JP2839232B2 (ja) * 1993-12-24 1998-12-16 理化学研究所 新規糖鎖合成酵素
JP2854803B2 (ja) * 1994-04-28 1999-02-10 理化学研究所 新規糖鎖合成酵素
US5955647A (en) * 1994-02-03 1999-09-21 The Scripps Research Institute Method for using tobacco mosaic virus to overproduce peptides and proteins
US5723755A (en) * 1995-05-16 1998-03-03 Francis E. Lefaivre Large scale production of human or animal proteins using plant bioreactors
US5939288A (en) * 1995-06-07 1999-08-17 Iowa State University Research Foundation, Inc. Plant secretory signal peptides and nectarins
FR2736930B1 (fr) * 1995-07-17 1997-09-19 Biocem Procede de production, par des cellules vegetales, de proteines heminiques, proteines ainsi obtenues et produits contenant ces proteines
AU6504796A (en) 1995-07-20 1997-02-18 Washington State University Research Foundation Production of secreted foreign polypeptides in plant cell culture
WO1997027303A1 (fr) * 1996-01-24 1997-07-31 Toyo Boseki Kabushiki Kaisha Alpha-1-6 fucosyltransferases
DE69738177T2 (de) * 1996-08-02 2008-07-03 The Austin Research Institute, Heidelberg Verbesserte nukleinsäuren, welche für eine chimäre glycosyltransferase kodieren
DE69823046T2 (de) 1997-01-16 2005-03-31 Neose Technologies, Inc. Praktische in vitro sialylierung von rekombinanten glykpproteinen
US6087115A (en) 1997-01-22 2000-07-11 Cornell Research Foundation, Inc. Methods of identifying negative antagonists for G protein coupled receptors
JP3921271B2 (ja) 1997-05-16 2007-05-30 生化学工業株式会社 グルクロン酸転移酵素をコードするｄｎａ
JP4003093B2 (ja) * 1997-07-29 2007-11-07 東洋紡績株式会社 糖類の製造方法
AU1585999A (en) 1997-11-12 1999-05-31 Neurotherapeutics Methods for the detection and treatment of disease using a glycosyltransferase
DE19754622A1 (de) * 1997-12-09 1999-06-10 Antje Von Dr Schaewen Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität
US6096546A (en) 1998-01-30 2000-08-01 Board Of Trustees, Rutgers, The State University Of New Jersey Methods for recovering polypeptides from plants and portions thereof
FR2774379B1 (fr) 1998-01-30 2002-03-29 Groupe Limagrain Holding Procede de production, par des cellules vegetales, d'alpha 1-antitrypsine et de ses variantes, et produits contenant l'alpha-antitrypsine ainsi obtenue
US5955282A (en) * 1998-04-03 1999-09-21 Incyte Pharmaceuticals, Inc. Human galactosyltransferases
ES2340112T3 (es) * 1998-04-20 2010-05-28 Glycart Biotechnology Ag Ingenieria de glicosilacion de anticuerpos para la mejora de la citotoxicidad celular dependiente de anticuerpos.
IL126967A (en) 1998-11-09 2002-09-12 Lightech Electronics Ind Ltd Electronic transformer for lighting
JP2002530087A (ja) 1998-11-18 2002-09-17 ネオーズ テクノロジーズ， インコーポレイテッド オリゴ糖の安価な産生
IL143641A0 (en) * 1998-12-09 2002-04-21 A method for manufacturing glycoproteins having human-type glycosylation
AT408446B (de) 1999-02-18 2001-11-26 Altmann Friedrich Dr Fucosyltransferase-gen
JP2000245470A (ja) * 1999-02-26 2000-09-12 Noda Inst For Scient Res 植物細胞間液による外来ポリペプチドの製造方法
EP1159406A4 (en) 1999-03-02 2002-10-30 Human Genome Sciences Inc HUMAN GLYCOSYLATION ENZYMES
JP2000287692A (ja) 1999-04-09 2000-10-17 Mitsui Chemicals Inc 糖タンパク質の有するｎ−結合型糖鎖の組成中、分岐数が異なる糖鎖の含有割合を制御する方法
WO2001029241A2 (en) 1999-10-15 2001-04-26 Calgene Llc Methods and vectors for site-specific recombination in plant cell plastids
CA2388432A1 (en) * 1999-10-21 2001-04-26 Monsanto Company Post-translational modification of recombinant proteins produced in plants
ATE478150T1 (de) 1999-10-26 2010-09-15 Stichting Dienst Landbouwkundi Säugetierartige glykosylierung in pflanzen
ES2349427T3 (es) 1999-10-26 2011-01-03 Stichting Dienst Landbouwkundig Onderzoek Glicosilación de tipo mamífero en plantas.
JP2001546898A (en) 1999-12-21 2003-06-10 Kyowa Hakko Kogyo Kk MODIFIED alpha -1,2-FUCOSYLTRANSFERASE GENE AND PROCESS FOR PRODUCING alpha -1,2-FUCOSYLTRANSFERASE AND FUCOSE-CONTAINING SUGAR CHAIN
AU2676801A (en) 1999-12-30 2001-07-16 Knut Kleesiek Xylosyltransferase and isoforms thereof
FR2803307A1 (fr) 1999-12-30 2001-07-06 Centre Nat Rech Scient Lignees de lymphocytes t cd4 specifiques de type th1 et procede pour leur induction ex vivo
WO2001062912A2 (en) 2000-02-24 2001-08-30 University Of Guelph Method of modulating glycosylation pathways
US20020174453A1 (en) * 2001-04-18 2002-11-21 Henry Daniell Production of antibodies in transgenic plastids
AT409381B (de) 2000-03-03 2002-07-25 Gloessl Josef Dr Xylosyltransferase-gen
FR2808286B1 (fr) 2000-04-26 2004-12-17 Agronomique Inst Nat Rech Nouvelle glucosidase i de plante et son application a la production de proteines recombinantes a glycosylation modifiee
WO2001082912A2 (en) 2000-04-28 2001-11-08 Gerolymatos P N Sa TREATMENT OF PATHOLOGICAL CONDITIONS INFLUENCED BY THE ACTION OF MATRIX METALLOPROTEINASES (MMPs) USING PHANQUINONE
EP1285072A2 (en) 2000-05-12 2003-02-26 Neose Technologies, Inc. In vitro fucosylation recombinant glycopeptides
EP1297172B1 (en) 2000-06-28 2005-11-09 Glycofi, Inc. Methods for producing modified glycoproteins
AU2002222965A1 (en) 2000-07-19 2002-01-30 Digimarc Corporation Print media with embedded messages for controlling printing
TW519716B (en) * 2000-12-19 2003-02-01 Tokyo Electron Ltd Wafer bias drive for a plasma source
CN100385006C (zh) 2001-01-19 2008-04-30 陶氏化学公司 利用植物细胞分泌性生产具有人型糖链的糖蛋白的方法
CN101781635A (zh) 2001-03-06 2010-07-21 陶氏化学公司 具有动物型糖链加成功能的植物细胞
DE50214430D1 (de) 2001-06-22 2010-06-24 Siemens Ag Video-rauchdetektionssystem und verfahren zu dessen überprüfung
WO2003007661A1 (fr) 2001-07-09 2003-01-23 Ibiden Co., Ltd. Appareil de chauffage en ceramique et article en ceramique soude
SE519261C2 (sv) 2001-07-17 2003-02-04 Sca Hygiene Prod Ab Absorberande alster
WO2003007861A1 (en) 2001-07-20 2003-01-30 Cutmed Ltd. System for performing a micro-drilling procedure in human or animal and a method for use thereof
PL217751B1 (pl) 2001-08-03 2014-08-29 Glycart Biotechnology Ag Zastosowanie glikomodyfikowanego przeciwciała do wytwarzania kompozycji farmaceutycznej do leczenia choroby wybranej z grupy składającej się z nowotworu, małopłytkowości autoimmunologicznej w przewlekłej chorobie przeszczep przeciwko gospodarzowi i immunozależnej nabytej aplazji czysto czerwonokrwinkowej
US20030175755A1 (en) 2002-03-05 2003-09-18 Yoshihiro Abiko Method of collecting data for estimation of susceptibility to periodontal disease
EP1485492B1 (en) 2002-03-19 2011-12-21 Stichting Dienst Landbouwkundig Onderzoek Gntiii (udp-n-acetylglucosamine:beta-d mannoside beta(1,4)-n-acetylglucosaminyltransferase iii) expression in plants
CA2478297C (en) 2002-03-19 2013-05-14 Plant Research International B.V. Optimizing glycan processing in plants
DE10229635C1 (de) 2002-07-02 2003-07-10 Ise Gmbh Überrollschutzsystem für Kraftfahrzeuge
AR042145A1 (es) * 2002-11-27 2005-06-08 Dow Agrociences Llc Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
DE602006015195D1 (de) * 2005-07-12 2010-08-12 Greenovation Biotech Gmbh Verbesserungen der proteinproduktion oder in zusammenhang damit
BRPI0810443A2 (pt) 2007-04-17 2016-09-27 Plant Res Int Bv glicosilação do tipo em mamífero em plantas através da expressão de glicosiltransferases de não mamíferos

Also Published As

Publication number Publication date
IL212887A0 (en) 2011-07-31
US20110030108A1 (en) 2011-02-03
BRPI0015031B1 (pt) 2017-05-30
EP2251426A1 (en) 2010-11-17
EP1772518B1 (en) 2010-08-18
DE60044858D1 (de) 2010-09-30
US20120237972A1 (en) 2012-09-20
TR200201121T2 (tr) 2003-01-21
US8193415B2 (en) 2012-06-05
CA2389217C (en) 2016-12-06
EP1228231B1 (en) 2007-06-20
US20080003680A1 (en) 2008-01-03
CA2389217A1 (en) 2001-05-03
DK1772518T3 (da) 2010-11-22
DE60035285D1 (de) 2007-08-02
IL212888A0 (en) 2011-07-31
WO2001031045A1 (en) 2001-05-03
PT1228231E (pt) 2007-09-25
PT1772518E (pt) 2010-10-28
IL204883A (en) 2012-05-31
BR0015031A (pt) 2002-06-18
IL149271A (en) 2010-11-30
CA2925231A1 (en) 2001-05-03
EP1772518A2 (en) 2007-04-11
ATE478150T1 (de) 2010-09-15
JP2003512076A (ja) 2003-04-02
ES2288882T3 (es) 2008-02-01
AU1738401A (en) 2001-05-08
EP1228231A1 (en) 2002-08-07
MXPA02004142A (es) 2003-08-20
IL212889A0 (en) 2011-07-31
IL149271A0 (en) 2002-11-10
EP1772518A3 (en) 2007-04-18
US8907163B2 (en) 2014-12-09
NZ518532A (en) 2004-02-27
DK1228231T3 (da) 2007-10-29
DE60035285T2 (de) 2008-02-21
IL212888A (en) 2017-12-31
ATE365219T1 (de) 2007-07-15
US7781647B2 (en) 2010-08-24
JP4890712B2 (ja) 2012-03-07

Similar Documents

Publication Publication Date Title
HK1105785A1 (en) Mammalian-type glycosylation in plants
WO2003078614A3 (en) Gntiii (udp-n-acethylglucosamine:beta-d mannoside beta (1,4)-n-acethylglucosaminy ltransferase iii) expression in plants
Olden et al. Function of glycoprotein glycans
FI91160B (fi) Menetelmä modifioidun ihmisen t-PA-proteiinin valmistamiseksi
BR0014945A (pt) Modificação pós-traducional de proteìnas recombinantes produzidas em plantas
DE69033032D1 (de) Integriertes zellkultur-proteinreinigungssystem zur automatisierten herstellung und reinigung von zellkulturprodukten
ITMI921417A1 (it) Impianto a moduli mobili per lo sviluppo e la produzione di prodotti biotecnologici su scala pilota
DE69133602D1 (de) Pflanzliche Thioesterasen
DK1137797T3 (da) Ekspressionssystem for faktor VIII
CA2034489A1 (en) Methods for the inactivation of viruses in viral-contaminated pharmaceutical compositions
CA2005502A1 (en) Somatotropin analogs
ATE239123T1 (de) Funktionelle faserprodukte
SE8801701D0 (sv) Production technology based on enzymic method
ATA3552000A (de) Xylosyltransferase-gen
ES2046552T3 (es) Procedimiento para la fabricacion de hidrolizados de proteinas con bajo contenido de sustancias amargantes.
DK0588177T3 (da) Interferon-alpha/beta-bindende protein, fremstilling heraf samt farmaceutiske præparater indeholdende proteinet
DK0929231T3 (da) Fremgangsmåde til behandling af planteproteiner og ernæringsprodukter fremstillet på basis heraf
WO2001051624A3 (en) Carboxypeptidase b free of animal products and contaminating enyzme activity
DK628188A (da) Protein og fremgangsmaade til fremstilling deraf
EP0497911A4 (en) Recombinant production of lactoperoxidase
AU4669889A (en) Supplements of animal cell culture media based on products derived from the milk industry
Welch Carpenter plans to buy Georgia ceramics firm
RU94031415A (ru) Способ измерения активности молокосвертывающих ферментных препаратов
IT1186468B (it) Sistema di taratura al laser di risuonatore di quarzo,e relativi prodotti

Legal Events

Date Code Title Description
CHRG Changes in the register

Free format text: CORRECTION OF THE NAME OF APPLICANT FROM STICHING DIENST LANDBOUWKUNDIG ONDERZOEK TO STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK

PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20171026