ATE478150T1 - Säugetierartige glykosylierung in pflanzen - Google Patents
Säugetierartige glykosylierung in pflanzenInfo
- Publication number
- ATE478150T1 ATE478150T1 AT06077065T AT06077065T ATE478150T1 AT E478150 T1 ATE478150 T1 AT E478150T1 AT 06077065 T AT06077065 T AT 06077065T AT 06077065 T AT06077065 T AT 06077065T AT E478150 T1 ATE478150 T1 AT E478150T1
- Authority
- AT
- Austria
- Prior art keywords
- plants
- normally
- glycosylation
- mammal
- present
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99203524 | 1999-10-26 | ||
EP99203523 | 1999-10-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE478150T1 true ATE478150T1 (de) | 2010-09-15 |
Family
ID=26153384
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06077065T ATE478150T1 (de) | 1999-10-26 | 2000-10-26 | Säugetierartige glykosylierung in pflanzen |
AT00980083T ATE365219T1 (de) | 1999-10-26 | 2000-10-26 | Glykolisierung des säugetiertyps in pflanzen |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00980083T ATE365219T1 (de) | 1999-10-26 | 2000-10-26 | Glykolisierung des säugetiertyps in pflanzen |
Country Status (17)
Country | Link |
---|---|
US (3) | US7781647B2 (de) |
EP (3) | EP1228231B1 (de) |
JP (1) | JP4890712B2 (de) |
AT (2) | ATE478150T1 (de) |
AU (1) | AU1738401A (de) |
BR (1) | BRPI0015031B1 (de) |
CA (2) | CA2925231A1 (de) |
DE (2) | DE60035285T2 (de) |
DK (2) | DK1228231T3 (de) |
ES (1) | ES2288882T3 (de) |
HK (1) | HK1105785A1 (de) |
IL (6) | IL149271A0 (de) |
MX (1) | MXPA02004142A (de) |
NZ (1) | NZ518532A (de) |
PT (2) | PT1228231E (de) |
TR (1) | TR200201121T2 (de) |
WO (1) | WO2001031045A1 (de) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL143641A0 (en) | 1998-12-09 | 2002-04-21 | A method for manufacturing glycoproteins having human-type glycosylation | |
CA2388432A1 (en) * | 1999-10-21 | 2001-04-26 | Monsanto Company | Post-translational modification of recombinant proteins produced in plants |
ATE478150T1 (de) | 1999-10-26 | 2010-09-15 | Stichting Dienst Landbouwkundi | Säugetierartige glykosylierung in pflanzen |
JP5623683B2 (ja) * | 2000-03-22 | 2014-11-12 | フィトン ホールディングス,リミティド ライアビリティ カンパニー | 動物型糖鎖付加機能をもつ植物細胞 |
FR2807767B1 (fr) | 2000-04-12 | 2005-01-14 | Lab Francais Du Fractionnement | Anticorps monoclonaux anti-d |
US7632983B2 (en) | 2000-07-31 | 2009-12-15 | Biolex Therapeutics, Inc. | Expression of monoclonal antibodies in duckweed |
US8022270B2 (en) | 2000-07-31 | 2011-09-20 | Biolex Therapeutics, Inc. | Expression of biologically active polypeptides in duckweed |
CN100385006C (zh) * | 2001-01-19 | 2008-04-30 | 陶氏化学公司 | 利用植物细胞分泌性生产具有人型糖链的糖蛋白的方法 |
CN101781635A (zh) * | 2001-03-06 | 2010-07-21 | 陶氏化学公司 | 具有动物型糖链加成功能的植物细胞 |
GB2377446B (en) * | 2001-07-13 | 2005-06-29 | Lars Erik Berglund | Expression of cobalamin binding proteins in transgenic plants |
EP1485492B1 (de) * | 2002-03-19 | 2011-12-21 | Stichting Dienst Landbouwkundig Onderzoek | Gntiii (udp-n-acetylglucosamin:beta-d-mannosid-beta(1,4)-n-acetylglucosaminyltransferase iii) expression in pflanzen |
AU2008202355B2 (en) * | 2002-03-19 | 2011-04-07 | Stichting Dienst Landbouwkundig Onderzoek | Optimizing glycan processing in plants |
CA2478297C (en) * | 2002-03-19 | 2013-05-14 | Plant Research International B.V. | Optimizing glycan processing in plants |
AU2013205260B2 (en) * | 2002-03-19 | 2016-02-18 | Stichting Dienst Landbouwkundig Onderzoek | Optimizing glycan processing in plants |
AR042145A1 (es) * | 2002-11-27 | 2005-06-08 | Dow Agrociences Llc | Produccion de inmunoglobulinas en plantas con una fucocilacion reducida |
SG179292A1 (en) * | 2003-01-22 | 2012-04-27 | Roche Glycart Ag | Fusion constructs and use of same to produce antibodies with increased fc receptor binding affinity and effector function |
EP1536229A1 (de) * | 2003-11-26 | 2005-06-01 | Plant Research International B.V. | Verfahren zur Identifizierung eines biomolekularen Profils |
AU2005233387B2 (en) * | 2004-04-15 | 2011-05-26 | Glycofi, Inc. | Production of galactosylated glycoproteins in lower eukaryotes |
US8617575B2 (en) | 2004-05-31 | 2013-12-31 | Kitasato Daiichi Sankyo Vaccine Co., Ltd. | Methods for conferring immunity against protozoans in an animal |
CA2570566A1 (en) * | 2004-06-25 | 2006-01-12 | Altor Bioscience Corporation | Production of tissue factor in plants |
JP2006288210A (ja) * | 2005-04-05 | 2006-10-26 | National Institute Of Advanced Industrial & Technology | 糖転移酵素遺伝子の導入による生体内糖鎖伸長の技術 |
DE602006015195D1 (de) * | 2005-07-12 | 2010-08-12 | Greenovation Biotech Gmbh | Verbesserungen der proteinproduktion oder in zusammenhang damit |
JP2009523432A (ja) | 2006-01-17 | 2009-06-25 | バイオレックス セラピュティックス インク | 植物中でのn−グリカンのヒト化及び最適化のための組成物及び方法 |
EP2224009B1 (de) | 2006-02-09 | 2012-10-31 | Medicago Inc. | Synthese von Sialinsäure in Pflanzen |
EP1878747A1 (de) | 2006-07-11 | 2008-01-16 | greenovation Biotech GmbH | Glyco-hergestellte Antikörper |
BRPI0810443A2 (pt) * | 2007-04-17 | 2016-09-27 | Plant Res Int Bv | glicosilação do tipo em mamífero em plantas através da expressão de glicosiltransferases de não mamíferos |
AU2013203379B2 (en) * | 2007-04-17 | 2016-01-21 | Stichting Dienst Landbouwkundig Onderzoek | Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases |
WO2008141806A1 (en) * | 2007-05-21 | 2008-11-27 | Bayer Bioscience N.V. | Methods and means for producing glycoproteins with altered glycosylation pattern in higher plants |
BRPI0812538B1 (pt) * | 2007-06-15 | 2021-03-16 | Medicago Inc. | processo para a síntese de uma proteína de interesse com fucosilação e xilosilação reduzidas, ácido nucleico, e proteína híbrida gnt1-galt |
AU2009270404B2 (en) | 2008-07-18 | 2015-01-29 | Medicago Inc. | New influenza virus immunizing epitope |
US8232073B2 (en) | 2009-01-02 | 2012-07-31 | Zacharon Pharmaceuticals, Inc. | Quantification of non-reducing end glycan residual compounds |
US9029530B2 (en) | 2009-01-02 | 2015-05-12 | Biomarin Pharmaceutical Inc. | Detection of oligosaccharides |
US8809009B2 (en) | 2009-01-02 | 2014-08-19 | Biomarin Pharmaceutical Inc. | Methods of diagnosing a disease and methods of monitoring treatment of a disease by quantifying a non-reducing end glycan residual compound and comparing to a second biomarker |
WO2010111713A2 (en) * | 2009-03-27 | 2010-09-30 | Zacharon Pharmaceuticals, Inc. | N-linked glycan biosynthesis modulators |
WO2013019625A2 (en) | 2011-07-29 | 2013-02-07 | The University Of Wyoming | Methods of using a bacterial glcnac-6-p 2'-epimerase to promote sialylation of glycoconjugates |
US9816107B2 (en) | 2011-07-29 | 2017-11-14 | The University Of Wyoming | Transgenic insect cells comprising a bacterial GlcNAc-6-P 2′-epimerase |
US9546219B2 (en) | 2012-02-08 | 2017-01-17 | North Carolina State University | Treatment of allergic diseases with recombinant antibodies |
US20140115728A1 (en) | 2012-10-24 | 2014-04-24 | A. Joseph Tector | Double knockout (gt/cmah-ko) pigs, organs and tissues |
CA3041717A1 (en) | 2016-11-09 | 2018-05-17 | North Carolina State University | Treatment of allergic diseases with chimeric protein |
EP3548612A4 (de) | 2016-12-01 | 2020-04-15 | Plantform Corporation | Transgene pflanze mit reduzierter fucosyltransferase- und xylosyltransferase-aktivität |
JP6934666B2 (ja) * | 2018-01-18 | 2021-09-15 | 国立研究開発法人産業技術総合研究所 | 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法 |
WO2019183437A1 (en) | 2018-03-23 | 2019-09-26 | North Carolina State University | Methods and compositions for antibody to high affinity receptor for ige |
USD1034550S1 (en) * | 2022-12-19 | 2024-07-09 | Shenzhen Xunweijia Technology Development Co., Ltd. | Microphone |
USD1034549S1 (en) * | 2022-12-19 | 2024-07-09 | Shenzhen Xunweijia Technology Development Co., Ltd. | Microphone |
Family Cites Families (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5455790A (en) | 1977-10-05 | 1979-05-04 | Tomoyuki Tajima | Production of erythropoetin |
JPS5616496A (en) | 1979-07-20 | 1981-02-17 | Sumitomo Chem Co Ltd | Recovery of erythropoietin |
JPS5653696A (en) | 1979-10-09 | 1981-05-13 | Ajinomoto Co Inc | Isolation of erythropoietin by adsorption |
JPS56108798A (en) | 1980-02-01 | 1981-08-28 | Green Cross Corp:The | Purification of erythropoietin |
JPS57149228A (en) | 1981-03-11 | 1982-09-14 | Ajinomoto Co Inc | Novel erythropoietin and its preparation |
JPS57169424A (en) | 1981-04-10 | 1982-10-19 | Toyo Shinyaku Kk | Preparation of erythropoietin |
US4956282A (en) * | 1985-07-29 | 1990-09-11 | Calgene, Inc. | Mammalian peptide expression in plant cells |
US5179198A (en) | 1988-07-11 | 1993-01-12 | Hidechika Okada | Glycoprotein and gene coding therefor |
US5959177A (en) * | 1989-10-27 | 1999-09-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
US5202422A (en) * | 1989-10-27 | 1993-04-13 | The Scripps Research Institute | Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins and method of their use |
WO1991016449A1 (en) * | 1990-04-16 | 1991-10-31 | The Trustees Of The University Of Pennsylvania | Saccharide compositions, methods and apparatus for their synthesis |
ES2164050T3 (es) | 1991-04-18 | 2002-02-16 | Toray Industries | Preparacion de compuestos de interleuquina-6. |
US5874271A (en) * | 1992-08-21 | 1999-02-23 | Takara Shuzo Co., Ltd. | Human glycosyltransferase gene, compounds and method for inhibiting cancerous metastasis |
WO1994012646A1 (en) | 1992-11-27 | 1994-06-09 | Ciba-Geigy Ag | Proteins having glycosyltransferase activity |
JPH09503905A (ja) * | 1993-07-15 | 1997-04-22 | ネオゼ ファーマシューティカルス | 糖組成物の合成方法 |
EP0737745A4 (de) | 1993-12-24 | 1999-06-16 | Rikagaku Kenkyusho | Neuartige synthetase für zuckerketten und verfahren für ihre herstellung |
JP2839232B2 (ja) * | 1993-12-24 | 1998-12-16 | 理化学研究所 | 新規糖鎖合成酵素 |
JP2854803B2 (ja) * | 1994-04-28 | 1999-02-10 | 理化学研究所 | 新規糖鎖合成酵素 |
US5955647A (en) * | 1994-02-03 | 1999-09-21 | The Scripps Research Institute | Method for using tobacco mosaic virus to overproduce peptides and proteins |
US5723755A (en) * | 1995-05-16 | 1998-03-03 | Francis E. Lefaivre | Large scale production of human or animal proteins using plant bioreactors |
US5939288A (en) * | 1995-06-07 | 1999-08-17 | Iowa State University Research Foundation, Inc. | Plant secretory signal peptides and nectarins |
FR2736930B1 (fr) * | 1995-07-17 | 1997-09-19 | Biocem | Procede de production, par des cellules vegetales, de proteines heminiques, proteines ainsi obtenues et produits contenant ces proteines |
AU6504796A (en) | 1995-07-20 | 1997-02-18 | Washington State University Research Foundation | Production of secreted foreign polypeptides in plant cell culture |
WO1997027303A1 (fr) * | 1996-01-24 | 1997-07-31 | Toyo Boseki Kabushiki Kaisha | Alpha-1-6 fucosyltransferases |
DE69738177T2 (de) * | 1996-08-02 | 2008-07-03 | The Austin Research Institute, Heidelberg | Verbesserte nukleinsäuren, welche für eine chimäre glycosyltransferase kodieren |
DE69823046T2 (de) | 1997-01-16 | 2005-03-31 | Neose Technologies, Inc. | Praktische in vitro sialylierung von rekombinanten glykpproteinen |
US6087115A (en) | 1997-01-22 | 2000-07-11 | Cornell Research Foundation, Inc. | Methods of identifying negative antagonists for G protein coupled receptors |
JP3921271B2 (ja) | 1997-05-16 | 2007-05-30 | 生化学工業株式会社 | グルクロン酸転移酵素をコードするdna |
JP4003093B2 (ja) * | 1997-07-29 | 2007-11-07 | 東洋紡績株式会社 | 糖類の製造方法 |
AU1585999A (en) | 1997-11-12 | 1999-05-31 | Neurotherapeutics | Methods for the detection and treatment of disease using a glycosyltransferase |
DE19754622A1 (de) * | 1997-12-09 | 1999-06-10 | Antje Von Dr Schaewen | Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität |
US6096546A (en) | 1998-01-30 | 2000-08-01 | Board Of Trustees, Rutgers, The State University Of New Jersey | Methods for recovering polypeptides from plants and portions thereof |
FR2774379B1 (fr) | 1998-01-30 | 2002-03-29 | Groupe Limagrain Holding | Procede de production, par des cellules vegetales, d'alpha 1-antitrypsine et de ses variantes, et produits contenant l'alpha-antitrypsine ainsi obtenue |
US5955282A (en) * | 1998-04-03 | 1999-09-21 | Incyte Pharmaceuticals, Inc. | Human galactosyltransferases |
ES2340112T3 (es) * | 1998-04-20 | 2010-05-28 | Glycart Biotechnology Ag | Ingenieria de glicosilacion de anticuerpos para la mejora de la citotoxicidad celular dependiente de anticuerpos. |
IL126967A (en) | 1998-11-09 | 2002-09-12 | Lightech Electronics Ind Ltd | Electronic transformer for lighting |
JP2002530087A (ja) | 1998-11-18 | 2002-09-17 | ネオーズ テクノロジーズ, インコーポレイテッド | オリゴ糖の安価な産生 |
IL143641A0 (en) * | 1998-12-09 | 2002-04-21 | A method for manufacturing glycoproteins having human-type glycosylation | |
AT408446B (de) | 1999-02-18 | 2001-11-26 | Altmann Friedrich Dr | Fucosyltransferase-gen |
JP2000245470A (ja) * | 1999-02-26 | 2000-09-12 | Noda Inst For Scient Res | 植物細胞間液による外来ポリペプチドの製造方法 |
EP1159406A4 (de) | 1999-03-02 | 2002-10-30 | Human Genome Sciences Inc | Menschliche glykosylierungsenzyme |
JP2000287692A (ja) | 1999-04-09 | 2000-10-17 | Mitsui Chemicals Inc | 糖タンパク質の有するn−結合型糖鎖の組成中、分岐数が異なる糖鎖の含有割合を制御する方法 |
WO2001029241A2 (en) | 1999-10-15 | 2001-04-26 | Calgene Llc | Methods and vectors for site-specific recombination in plant cell plastids |
CA2388432A1 (en) * | 1999-10-21 | 2001-04-26 | Monsanto Company | Post-translational modification of recombinant proteins produced in plants |
ATE478150T1 (de) | 1999-10-26 | 2010-09-15 | Stichting Dienst Landbouwkundi | Säugetierartige glykosylierung in pflanzen |
ES2349427T3 (es) | 1999-10-26 | 2011-01-03 | Stichting Dienst Landbouwkundig Onderzoek | Glicosilación de tipo mamífero en plantas. |
JP2001546898A (en) | 1999-12-21 | 2003-06-10 | Kyowa Hakko Kogyo Kk | MODIFIED alpha -1,2-FUCOSYLTRANSFERASE GENE AND PROCESS FOR PRODUCING alpha -1,2-FUCOSYLTRANSFERASE AND FUCOSE-CONTAINING SUGAR CHAIN |
AU2676801A (en) | 1999-12-30 | 2001-07-16 | Knut Kleesiek | Xylosyltransferase and isoforms thereof |
FR2803307A1 (fr) | 1999-12-30 | 2001-07-06 | Centre Nat Rech Scient | Lignees de lymphocytes t cd4 specifiques de type th1 et procede pour leur induction ex vivo |
WO2001062912A2 (en) | 2000-02-24 | 2001-08-30 | University Of Guelph | Method of modulating glycosylation pathways |
US20020174453A1 (en) * | 2001-04-18 | 2002-11-21 | Henry Daniell | Production of antibodies in transgenic plastids |
AT409381B (de) | 2000-03-03 | 2002-07-25 | Gloessl Josef Dr | Xylosyltransferase-gen |
FR2808286B1 (fr) | 2000-04-26 | 2004-12-17 | Agronomique Inst Nat Rech | Nouvelle glucosidase i de plante et son application a la production de proteines recombinantes a glycosylation modifiee |
WO2001082912A2 (en) | 2000-04-28 | 2001-11-08 | Gerolymatos P N Sa | TREATMENT OF PATHOLOGICAL CONDITIONS INFLUENCED BY THE ACTION OF MATRIX METALLOPROTEINASES (MMPs) USING PHANQUINONE |
EP1285072A2 (de) | 2000-05-12 | 2003-02-26 | Neose Technologies, Inc. | In vitro fucosylierung von rekombinanten glycoproteinen |
EP1297172B1 (de) | 2000-06-28 | 2005-11-09 | Glycofi, Inc. | Verfahren für die herstellung modifizierter glykoproteine |
AU2002222965A1 (en) | 2000-07-19 | 2002-01-30 | Digimarc Corporation | Print media with embedded messages for controlling printing |
TW519716B (en) * | 2000-12-19 | 2003-02-01 | Tokyo Electron Ltd | Wafer bias drive for a plasma source |
CN100385006C (zh) | 2001-01-19 | 2008-04-30 | 陶氏化学公司 | 利用植物细胞分泌性生产具有人型糖链的糖蛋白的方法 |
CN101781635A (zh) | 2001-03-06 | 2010-07-21 | 陶氏化学公司 | 具有动物型糖链加成功能的植物细胞 |
DE50214430D1 (de) | 2001-06-22 | 2010-06-24 | Siemens Ag | Video-rauchdetektionssystem und verfahren zu dessen überprüfung |
WO2003007661A1 (fr) | 2001-07-09 | 2003-01-23 | Ibiden Co., Ltd. | Appareil de chauffage en ceramique et article en ceramique soude |
SE519261C2 (sv) | 2001-07-17 | 2003-02-04 | Sca Hygiene Prod Ab | Absorberande alster |
WO2003007861A1 (en) | 2001-07-20 | 2003-01-30 | Cutmed Ltd. | System for performing a micro-drilling procedure in human or animal and a method for use thereof |
PL217751B1 (pl) | 2001-08-03 | 2014-08-29 | Glycart Biotechnology Ag | Zastosowanie glikomodyfikowanego przeciwciała do wytwarzania kompozycji farmaceutycznej do leczenia choroby wybranej z grupy składającej się z nowotworu, małopłytkowości autoimmunologicznej w przewlekłej chorobie przeszczep przeciwko gospodarzowi i immunozależnej nabytej aplazji czysto czerwonokrwinkowej |
US20030175755A1 (en) | 2002-03-05 | 2003-09-18 | Yoshihiro Abiko | Method of collecting data for estimation of susceptibility to periodontal disease |
EP1485492B1 (de) | 2002-03-19 | 2011-12-21 | Stichting Dienst Landbouwkundig Onderzoek | Gntiii (udp-n-acetylglucosamin:beta-d-mannosid-beta(1,4)-n-acetylglucosaminyltransferase iii) expression in pflanzen |
CA2478297C (en) | 2002-03-19 | 2013-05-14 | Plant Research International B.V. | Optimizing glycan processing in plants |
DE10229635C1 (de) | 2002-07-02 | 2003-07-10 | Ise Gmbh | Überrollschutzsystem für Kraftfahrzeuge |
AR042145A1 (es) * | 2002-11-27 | 2005-06-08 | Dow Agrociences Llc | Produccion de inmunoglobulinas en plantas con una fucocilacion reducida |
DE602006015195D1 (de) * | 2005-07-12 | 2010-08-12 | Greenovation Biotech Gmbh | Verbesserungen der proteinproduktion oder in zusammenhang damit |
BRPI0810443A2 (pt) | 2007-04-17 | 2016-09-27 | Plant Res Int Bv | glicosilação do tipo em mamífero em plantas através da expressão de glicosiltransferases de não mamíferos |
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