HK1037918A1 - olymorph of ritonavir. - Google Patents

olymorph of ritonavir.

Info

Publication number: HK1037918A1
Authority: HK; Hong Kong
Prior art keywords: olymorph; ritonavir
Prior art date: 1998-07-20

Application number

HK01107867A

Other languages

English (en)

Inventor

John F Bauer

Azita Saleki-Gerhardt

Bikshandarkoil A Narayanan

Sanjay R Chemburkar

Ketan Patel

Harry O Spiwek

Philip E Bauer

Kimberly A Allen

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-07-20

Filing date

2001-11-08

Publication date

2002-02-22

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26817251&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1037918(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-11-08 Application filed by Abbott Lab filed Critical Abbott Lab

2002-02-22 Publication of HK1037918A1 publication Critical patent/HK1037918A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Virology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
AIDS & HIV (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Steroid Compounds (AREA)
Crystals, And After-Treatments Of Crystals (AREA)
Medicinal Preparation (AREA)

HK01107867A 1998-07-20 2001-11-08 olymorph of ritonavir. HK1037918A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US11934598A	1998-07-20	1998-07-20
US32609399A	1999-06-04	1999-06-04
PCT/US1999/016334 WO2000004016A2 (en)	1998-07-20	1999-07-19	Polymorph of ritonavir

Publications (1)

Publication Number	Publication Date
HK1037918A1 true HK1037918A1 (en)	2002-02-22

Family

ID=26817251

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
HK01107867A HK1037918A1 (en)	1998-07-20	2001-11-08	olymorph of ritonavir.
HK09100857A HK1121155A1 (en)	1998-07-20	2009-01-29	A pharmaceutical composition comprising form ii crystalline ritonavir and a preparation thereof

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
HK09100857A HK1121155A1 (en)	1998-07-20	2009-01-29	A pharmaceutical composition comprising form ii crystalline ritonavir and a preparation thereof

Country Status (30)

Country	Link
EP (4)	EP2298751A3 (el)
JP (4)	JP4815050B2 (el)
KR (3)	KR100853371B1 (el)
CN (5)	CN102153524A (el)
AR (5)	AR019431A1 (el)
AT (3)	ATE261947T1 (el)
AU (1)	AU768207B2 (el)
BG (4)	BG65150B1 (el)
BR (1)	BR9912010A (el)
CA (3)	CA2674800A1 (el)
CO (1)	CO5090830A1 (el)
CY (2)	CY1111600T1 (el)
CZ (2)	CZ307116B6 (el)
DE (2)	DE69915628T2 (el)
DK (3)	DK2017269T3 (el)
ES (3)	ES2372990T3 (el)
HK (2)	HK1037918A1 (el)
HU (3)	HU230150B1 (el)
ID (1)	ID27996A (el)
IL (4)	IL140492A0 (el)
MY (2)	MY121765A (el)
NO (2)	NO318385B1 (el)
NZ (2)	NZ509125A (el)
PL (2)	PL194710B1 (el)
PT (3)	PT2017269E (el)
SI (3)	SI2017269T1 (el)
SK (3)	SK286388B6 (el)
TR (1)	TR200100171T2 (el)
TW (3)	TWI227713B (el)
WO (1)	WO2000004016A2 (el)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6894171B1 (en)	1998-07-20	2005-05-17	Abbott Laboratories	Polymorph of a pharmaceutical
MY121765A (en) *	1998-07-20	2006-02-28	Abbott Lab	Polymorph of ritonavir
ATE429224T1 (de) *	1999-06-04	2009-05-15	Abbott Lab	Arzneizubereitungen enthaltend mindestens einen hiv preoteaseinhibitor
MXPA03010771A (es) *	2001-05-25	2004-07-01	Abbott Lab	Capsulas elasticas blandas que comprenden ritonavir y/o lopinavir.
TWI286476B (en) *	2001-12-12	2007-09-11	Tibotec Pharm Ltd	Combination of cytochrome P450 dependent protease inhibitors
US7205413B2 (en)	2002-05-03	2007-04-17	Transform Pharmaceuticals, Inc.	Solvates and polymorphs of ritonavir and methods of making and using the same
US8377952B2 (en) *	2003-08-28	2013-02-19	Abbott Laboratories	Solid pharmaceutical dosage formulation
BRPI0401742B8 (pt)	2004-05-13	2021-05-25	Cristalia Produtos Quim Farmaceuticos Ltda	composto análogo do ritonavir útil como inibidor de protease retroviral, preparação do composto análogo do ritonavir e composição farmacêutica do composto análogo do ritonavir
US20080312300A1 (en) *	2005-05-30	2008-12-18	Yoginder Pal Sachdeva	Processes for the Preparation of Stable Polymorphic Form I of Ritonavir
US20100099885A1 (en) *	2006-10-03	2010-04-22	Mukesh Kumar Sharma	Process for the preparation of form i and form ii of ritonavir
CN102898398B (zh) *	2011-07-27	2015-01-14	上海迪赛诺药业有限公司	一种制备i型利托那韦多晶型结晶的方法
WO2013131646A1 (en)	2012-03-07	2013-09-12	Ratiopharm Gmbh	Dosage form comprising lopinavir and ritonavir
HUE027829T2 (en)	2012-03-07	2016-11-28	Ratiopharm Gmbh	Dosage forms containing non-crystalline lopinavir and crystalline ritonavir
CA2918707A1 (en)	2013-08-29	2015-03-05	Teva Pharmaceuticals Industries Ltd.	Unit dosage form comprising emtricitabine, tenofovir, darunavir and ritonavir and a monolithic tablet comprising darunavir and ritonavir
EP3129009A1 (en)	2014-04-08	2017-02-15	Teva Pharmaceutical Industries Ltd	Unit dosage form comprising emtricitabine, tenofovir, darunavir and ritonavir
CN106749085B (zh) *	2016-12-23	2019-05-24	东北制药集团股份有限公司	一种制备利托那韦的方法
EP3569225A1 (en)	2018-05-18	2019-11-20	Pharmaceutical Oriented Services Ltd	Solid dispersion containing ritonavir
RU2759544C1 (ru) *	2021-01-29	2021-11-15	Общество с ограниченной ответственностью "АМЕДАРТ"	Твёрдая фармацевтическая композиция для изготовления перорального терапевтического средства для профилактики и/или лечения ВИЧ-инфекции

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5696270A (en)	1989-05-23	1997-12-09	Abbott Laboratories	Intermediate for making retroviral protease inhibiting compounds
US5354866A (en)	1989-05-23	1994-10-11	Abbott Laboratories	Retroviral protease inhibiting compounds
EP0674513B1 (en) *	1992-12-29	1996-09-25	Abbott Laboratories	Retroviral protease inhibiting compounds
IL110752A (en)	1993-09-13	2000-07-26	Abbott Lab	Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor
US5559158A (en) *	1993-10-01	1996-09-24	Abbott Laboratories	Pharmaceutical composition
US5491253A (en)	1993-10-22	1996-02-13	Abbott Laboratories	Process for the preparation of a substituted 2,5-diamino-3-hydroxyhexane
IL111991A (en) *	1994-01-28	2000-07-26	Abbott Lab	Liquid pharmaceutical composition of HIV protease inhibitors in organic solvent
US5567823A (en) *	1995-06-06	1996-10-22	Abbott Laboratories	Process for the preparation of an HIV protease inhibiting compound
US6037157A (en) *	1995-06-29	2000-03-14	Abbott Laboratories	Method for improving pharmacokinetics
US6160122A (en)	1996-06-28	2000-12-12	Abbott Laboratories	Process for the preparation of a disubstituted thiazole
ZA9710071B (en)	1996-11-21	1998-05-25	Abbott Lab	Pharmaceutical composition.
MY121765A (en) *	1998-07-20	2006-02-28	Abbott Lab	Polymorph of ritonavir
DE19856432A1 (de) *	1998-12-08	2000-06-15	Basf Ag	Nanopartikuläre Kern-Schale Systeme sowie deren Verwendung in pharmazeutischen und kosmetischen Zubereitungen
ATE429224T1 (de) *	1999-06-04	2009-05-15	Abbott Lab	Arzneizubereitungen enthaltend mindestens einen hiv preoteaseinhibitor

1999
- 1999-07-16 MY MYPI9903007 patent/MY121765A/en unknown
- 1999-07-16 MY MYPI0402546 patent/MY145265A/en unknown
- 1999-07-16 CO CO99045166A patent/CO5090830A1/es unknown
- 1999-07-19 AT AT99934143T patent/ATE261947T1/de active
- 1999-07-19 IL IL14049299A patent/IL140492A0/xx unknown
- 1999-07-19 JP JP2000560122A patent/JP4815050B2/ja not_active Expired - Lifetime
- 1999-07-19 BR BR9912010A patent/BR9912010A/pt not_active Application Discontinuation
- 1999-07-19 HU HU0800266A patent/HU230150B1/hu unknown
- 1999-07-19 ES ES08007622T patent/ES2372990T3/es not_active Expired - Lifetime
- 1999-07-19 SI SI9931066T patent/SI2017269T1/sl unknown
- 1999-07-19 NZ NZ50912599A patent/NZ509125A/xx not_active IP Right Cessation
- 1999-07-19 KR KR1020067022587A patent/KR100853371B1/ko not_active IP Right Cessation
- 1999-07-19 CN CN2011100389228A patent/CN102153524A/zh active Pending
- 1999-07-19 PT PT08007622T patent/PT2017269E/pt unknown
- 1999-07-19 EP EP20100179472 patent/EP2298751A3/en not_active Withdrawn
- 1999-07-19 CA CA 2674800 patent/CA2674800A1/en not_active Abandoned
- 1999-07-19 HU HU0800267A patent/HU229999B1/hu unknown
- 1999-07-19 EP EP20080007622 patent/EP2017269B1/en not_active Expired - Lifetime
- 1999-07-19 CZ CZ2006-533A patent/CZ307116B6/cs not_active IP Right Cessation
- 1999-07-19 SK SK92-2001A patent/SK286388B6/sk not_active IP Right Cessation
- 1999-07-19 ID ID20010165A patent/ID27996A/id unknown
- 1999-07-19 CN CN998089273A patent/CN1310715B/zh not_active Expired - Lifetime
- 1999-07-19 CN CN2010101669679A patent/CN101966180A/zh active Pending
- 1999-07-19 PT PT03029709T patent/PT1418174E/pt unknown
- 1999-07-19 SK SK5029-2008A patent/SK287381B6/sk not_active IP Right Cessation
- 1999-07-19 PL PL99348033A patent/PL194710B1/pl unknown
- 1999-07-19 DK DK08007622T patent/DK2017269T3/da active
- 1999-07-19 DK DK99934143T patent/DK1097148T3/da active
- 1999-07-19 AU AU50037/99A patent/AU768207B2/en not_active Expired
- 1999-07-19 AT AT08007622T patent/ATE534636T1/de active
- 1999-07-19 KR KR1020017000857A patent/KR100793046B1/ko not_active IP Right Cessation
- 1999-07-19 HU HU0103823A patent/HU227540B1/hu unknown
- 1999-07-19 ES ES99934143T patent/ES2214038T3/es not_active Expired - Lifetime
- 1999-07-19 EP EP20030029709 patent/EP1418174B1/en not_active Expired - Lifetime
- 1999-07-19 CN CNA2003101181720A patent/CN1502613A/zh active Pending
- 1999-07-19 CA CA 2510949 patent/CA2510949C/en not_active Expired - Lifetime
- 1999-07-19 ES ES03029709T patent/ES2322759T3/es not_active Expired - Lifetime
- 1999-07-19 SI SI9930586T patent/SI1097148T1/xx unknown
- 1999-07-19 PT PT99934143T patent/PT1097148E/pt unknown
- 1999-07-19 SK SK5028-2008A patent/SK287586B6/sk not_active IP Right Cessation
- 1999-07-19 SI SI9931030T patent/SI1418174T1/sl unknown
- 1999-07-19 WO PCT/US1999/016334 patent/WO2000004016A2/en active Application Filing
- 1999-07-19 CA CA 2337846 patent/CA2337846C/en not_active Expired - Lifetime
- 1999-07-19 DE DE1999615628 patent/DE69915628T2/de not_active Expired - Lifetime
- 1999-07-19 AT AT03029709T patent/ATE425974T1/de active
- 1999-07-19 CN CNA2008100805471A patent/CN101259128A/zh active Pending
- 1999-07-19 EP EP19990934143 patent/EP1097148B1/en not_active Expired - Lifetime
- 1999-07-19 PL PL381194A patent/PL213978B1/pl unknown
- 1999-07-19 KR KR1020047011204A patent/KR100740796B1/ko not_active IP Right Cessation
- 1999-07-19 NZ NZ522690A patent/NZ522690A/en not_active IP Right Cessation
- 1999-07-19 CZ CZ20010203A patent/CZ298188B6/cs not_active IP Right Cessation
- 1999-07-19 DK DK03029709T patent/DK1418174T3/da active
- 1999-07-19 TR TR200100171T patent/TR200100171T2/xx unknown
- 1999-07-19 DE DE69940616T patent/DE69940616D1/de not_active Expired - Lifetime
- 1999-07-20 AR ARP990103557 patent/AR019431A1/es active IP Right Grant
- 1999-07-31 TW TW88112226A patent/TWI227713B/zh not_active IP Right Cessation
- 1999-07-31 TW TW90127014A patent/TWI271400B/zh not_active IP Right Cessation
- 1999-07-31 TW TW95132288A patent/TWI362382B/zh not_active IP Right Cessation
2000
- 2000-12-22 IL IL14049200A patent/IL140492A/en not_active IP Right Cessation
2001
- 2001-01-18 NO NO20010298A patent/NO318385B1/no not_active IP Right Cessation
- 2001-01-30 BG BG105197A patent/BG65150B1/bg unknown
- 2001-11-08 HK HK01107867A patent/HK1037918A1/xx not_active IP Right Cessation
2004
- 2004-04-20 AR ARP040101329 patent/AR044029A2/es not_active Application Discontinuation
- 2004-06-09 NO NO20042393A patent/NO327320B1/no not_active IP Right Cessation
2005
- 2005-06-29 AR ARP050102703 patent/AR049658A2/es not_active Application Discontinuation
2006
- 2006-09-20 BG BG109682A patent/BG65963B1/bg unknown
- 2006-09-20 BG BG110080A patent/BG110080A/bg unknown
2007
- 2007-03-06 AR ARP070100928 patent/AR059763A2/es unknown
- 2007-03-06 AR ARP070100929 patent/AR059764A2/es not_active Application Discontinuation
- 2007-11-05 IL IL18718107A patent/IL187181A/en not_active IP Right Cessation
2008
- 2008-03-12 BG BG10110080A patent/BG66140B1/bg unknown
- 2008-05-20 IL IL191582A patent/IL191582A/en not_active IP Right Cessation
2009
- 2009-01-29 HK HK09100857A patent/HK1121155A1/xx not_active IP Right Cessation
- 2009-06-11 CY CY20091100614T patent/CY1111600T1/el unknown
2010
- 2010-07-22 JP JP2010164769A patent/JP5732212B2/ja not_active Expired - Lifetime
2011
- 2011-12-05 CY CY20111101205T patent/CY1112139T1/el unknown
2013
- 2013-12-11 JP JP2013255680A patent/JP2014074047A/ja active Pending
2016
- 2016-10-21 JP JP2016206663A patent/JP2017061475A/ja active Pending

Also Published As

Publication number	Publication date
HUP0103823A3 (en)	2003-05-28
WO2000004016A3 (en)	2000-03-30
SI1097148T1 (en)	2004-10-31
EP1418174B1 (en)	2009-03-18
ATE261947T1 (de)	2004-04-15
SI1418174T1 (sl)	2009-08-31
NZ509125A (en)	2003-02-28
IL187181A (en)	2009-09-01
JP4815050B2 (ja)	2011-11-16
KR100853371B1 (ko)	2008-08-22
CZ307116B6 (cs)	2018-01-24
CY1111600T1 (el)	2015-10-07
NO327320B1 (no)	2009-06-08
SK287586B6 (sk)	2011-03-04
CA2674800A1 (en)	2000-01-27
JP2010270135A (ja)	2010-12-02
KR20060118022A (ko)	2006-11-17
JP5732212B2 (ja)	2015-06-10
AR059764A2 (es)	2008-04-30
BG66140B1 (bg)	2011-07-29
WO2000004016A2 (en)	2000-01-27
CA2337846A1 (en)	2000-01-27
EP2017269B1 (en)	2011-11-23
JP2017061475A (ja)	2017-03-30
SK287381B6 (sk)	2010-08-09
IL191582A0 (en)	2008-12-29
CN1310715A (zh)	2001-08-29
CN1502613A (zh)	2004-06-09
ES2214038T3 (es)	2004-09-01
HU0800267D0 (en)	2008-06-30
ES2372990T3 (es)	2012-01-30
CO5090830A1 (es)	2001-10-30
BG110080A (bg)	2008-11-28
CA2510949C (en)	2009-11-17
DE69915628T2 (de)	2004-08-12
EP1418174A3 (en)	2004-06-23
PT1418174E (pt)	2009-06-08
EP2298751A2 (en)	2011-03-23
DK1097148T3 (da)	2004-04-26
EP1418174A2 (en)	2004-05-12
JP2002520410A (ja)	2002-07-09
EP2017269A3 (en)	2009-06-10
CZ298188B6 (cs)	2007-07-18
TWI227713B (en)	2005-02-11
NO20010298D0 (no)	2001-01-18
ATE425974T1 (de)	2009-04-15
AU5003799A (en)	2000-02-07
KR100740796B1 (ko)	2007-07-20
CN102153524A (zh)	2011-08-17
TW200716550A (en)	2007-05-01
SK922001A3 (en)	2001-07-10
NO20010298L (no)	2001-01-18
IL191582A (en)	2016-02-29
BR9912010A (pt)	2001-04-10
EP2017269A2 (en)	2009-01-21
KR20010072003A (ko)	2001-07-31
CN101966180A (zh)	2011-02-09
JP2014074047A (ja)	2014-04-24
BG109682A (bg)	2007-03-30
DE69940616D1 (de)	2009-04-30
EP2298751A3 (en)	2011-08-17
SI2017269T1 (sl)	2012-02-29
ID27996A (id)	2001-05-03
HU0800266D0 (en)	2008-06-30
HK1121155A1 (en)	2009-04-17
NO318385B1 (no)	2005-03-14
AR059763A2 (es)	2008-04-30
TR200100171T2 (tr)	2001-05-21
MY121765A (en)	2006-02-28
EP2017269A8 (en)	2009-09-30
CY1112139T1 (el)	2015-11-04
TWI271400B (en)	2007-01-21
DK1418174T3 (da)	2009-05-18
NZ522690A (en)	2004-04-30
PT1097148E (pt)	2004-05-31
CN101259128A (zh)	2008-09-10
KR20040081137A (ko)	2004-09-20
NO20042393L (no)	2001-01-18
AR019431A1 (es)	2002-02-20
PL194710B1 (pl)	2007-06-29
CN1310715B (zh)	2010-11-03
MY145265A (en)	2012-01-13
PL348033A1 (en)	2002-05-06
ATE534636T1 (de)	2011-12-15
CZ2006533A3 (cs)	2001-05-16
HU227540B1 (en)	2011-08-29
HUP0103823A2 (hu)	2002-02-28
AR049658A2 (es)	2006-08-23
EP2017269A9 (en)	2009-10-14
EP1097148A2 (en)	2001-05-09
AU768207B2 (en)	2003-12-04
BG65150B1 (bg)	2007-04-30
KR100793046B1 (ko)	2008-01-10
EP1097148B1 (en)	2004-03-17
DE69915628D1 (en)	2004-04-22
PT2017269E (pt)	2011-12-20
HU230150B1 (hu)	2015-09-28
AR044029A2 (es)	2005-08-24
BG105197A (en)	2001-10-31
ES2322759T3 (es)	2009-06-26
CA2337846C (en)	2006-02-21
IL140492A0 (en)	2002-02-10
IL140492A (en)	2010-12-30
DK2017269T3 (da)	2012-03-05
SK286388B6 (sk)	2008-09-05
IL187181A0 (en)	2008-02-09
PL213978B1 (pl)	2013-05-31
CA2510949A1 (en)	2000-01-27
BG65963B1 (bg)	2010-07-30
TWI362382B (en)	2012-04-21
CZ2001203A3 (en)	2001-05-16
HU229999B1 (en)	2015-04-28

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2019-07-26	PE	Patent expired	Effective date: 20190718