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PT1097148E - Polimorfo de ritonavir - Google Patents

Polimorfo de ritonavir

Info

Publication number
PT1097148E
PT1097148E PT99934143T PT99934143T PT1097148E PT 1097148 E PT1097148 E PT 1097148E PT 99934143 T PT99934143 T PT 99934143T PT 99934143 T PT99934143 T PT 99934143T PT 1097148 E PT1097148 E PT 1097148E
Authority
PT
Portugal
Prior art keywords
polymerfo
ritonavir
ritonavir polymerfo
Prior art date
Application number
PT99934143T
Other languages
English (en)
Inventor
John F Bauer
Sanjay R Chemburkar
Azita Saleki-Gerhard
Bikshandarkoil A Narayanan
Ketan Patel
Harry O Spiwek
Philip E Bauer
Kimberly A Allen
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26817251&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1097148(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of PT1097148E publication Critical patent/PT1097148E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
PT99934143T 1998-07-20 1999-07-19 Polimorfo de ritonavir PT1097148E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11934598A 1998-07-20 1998-07-20
US32609399A 1999-06-04 1999-06-04

Publications (1)

Publication Number Publication Date
PT1097148E true PT1097148E (pt) 2004-05-31

Family

ID=26817251

Family Applications (3)

Application Number Title Priority Date Filing Date
PT08007622T PT2017269E (pt) 1998-07-20 1999-07-19 Composição farmacêutica que compreende a forma ii cristalina de ritonavir e uma sua preparação
PT03029709T PT1418174E (pt) 1998-07-20 1999-07-19 Ritonavir amorfo
PT99934143T PT1097148E (pt) 1998-07-20 1999-07-19 Polimorfo de ritonavir

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PT08007622T PT2017269E (pt) 1998-07-20 1999-07-19 Composição farmacêutica que compreende a forma ii cristalina de ritonavir e uma sua preparação
PT03029709T PT1418174E (pt) 1998-07-20 1999-07-19 Ritonavir amorfo

Country Status (29)

Country Link
EP (4) EP1418174B1 (pt)
JP (4) JP4815050B2 (pt)
KR (3) KR100740796B1 (pt)
CN (5) CN1310715B (pt)
AR (5) AR019431A1 (pt)
AT (3) ATE534636T1 (pt)
AU (1) AU768207B2 (pt)
BG (4) BG65150B1 (pt)
BR (1) BR9912010A (pt)
CA (3) CA2674800A1 (pt)
CO (1) CO5090830A1 (pt)
CY (2) CY1111600T1 (pt)
CZ (2) CZ307116B6 (pt)
DE (2) DE69940616D1 (pt)
DK (3) DK1097148T3 (pt)
ES (3) ES2372990T3 (pt)
HU (3) HU227540B1 (pt)
ID (1) ID27996A (pt)
IL (4) IL140492A0 (pt)
MY (2) MY145265A (pt)
NO (2) NO318385B1 (pt)
NZ (2) NZ509125A (pt)
PL (2) PL194710B1 (pt)
PT (3) PT2017269E (pt)
SI (3) SI1097148T1 (pt)
SK (3) SK286388B6 (pt)
TR (1) TR200100171T2 (pt)
TW (3) TWI362382B (pt)
WO (1) WO2000004016A2 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5090830A1 (es) * 1998-07-20 2001-10-30 Abbott Lab Poliformo de un agente farmaceutico
US6894171B1 (en) 1998-07-20 2005-05-17 Abbott Laboratories Polymorph of a pharmaceutical
KR100815412B1 (ko) * 1999-06-04 2008-03-20 아보트 러보러터리즈 개선된 약제학적 제형
WO2002096395A1 (en) * 2001-05-25 2002-12-05 Abbott Laboratories Soft elastic capsules comprising ritonavir and/or lopinavir
AR037797A1 (es) * 2001-12-12 2004-12-01 Tibotec Pharm Ltd Combinacion de inhibidores de proteasa dependientes del citocromo p450
US7205413B2 (en) 2002-05-03 2007-04-17 Transform Pharmaceuticals, Inc. Solvates and polymorphs of ritonavir and methods of making and using the same
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
BRPI0401742B8 (pt) 2004-05-13 2021-05-25 Cristalia Produtos Quim Farmaceuticos Ltda composto análogo do ritonavir útil como inibidor de protease retroviral, preparação do composto análogo do ritonavir e composição farmacêutica do composto análogo do ritonavir
US20080312300A1 (en) * 2005-05-30 2008-12-18 Yoginder Pal Sachdeva Processes for the Preparation of Stable Polymorphic Form I of Ritonavir
EP2077903A2 (en) * 2006-10-03 2009-07-15 Ranbaxy Laboratories, Ltd. Process for the preparation of form i and form ii of ritonavir
CN102898398B (zh) * 2011-07-27 2015-01-14 上海迪赛诺药业有限公司 一种制备i型利托那韦多晶型结晶的方法
EP2822554B1 (en) 2012-03-07 2016-05-18 ratiopharm GmbH Dosage form comprising lopinavir and ritonavir
EP2822553B1 (en) 2012-03-07 2016-05-18 ratiopharm GmbH Dosage form comprising non-crystalline lopinavir and crystalline ritonavir
MX2016002560A (es) 2013-08-29 2016-10-26 Teva Pharma Forma de dosificacion unitaria que comprende emtricitabina, tenofovir, darunavir y ritonavir y un comprimido monolitico que comprende darunavir y ritonavir.
TW201622731A (zh) 2014-04-08 2016-07-01 泰瓦藥品工業有限公司 包含恩曲他濱（Ｅｍｔｒｉｃｉｔａｂｉｎｅ）、替諾福韋（Ｔｅｎｏｆｏｖｉｒ）、地瑞那韋（Ｄａｒｕｎａｖｉｒ）及利托那韋（Ｒｉｔｏｎａｖｉｒ）之單位劑型以及包含地瑞那韋及利托那韋之單層錠劑
CN106749085B (zh) * 2016-12-23 2019-05-24 东北制药集团股份有限公司 一种制备利托那韦的方法
EP3569225A1 (en) 2018-05-18 2019-11-20 Pharmaceutical Oriented Services Ltd Solid dispersion containing ritonavir
RU2759544C1 (ru) * 2021-01-29 2021-11-15 Общество с ограниченной ответственностью "АМЕДАРТ" Твёрдая фармацевтическая композиция для изготовления перорального терапевтического средства для профилактики и/или лечения ВИЧ-инфекции

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5354866A (en) 1989-05-23 1994-10-11 Abbott Laboratories Retroviral protease inhibiting compounds
US5552558A (en) * 1989-05-23 1996-09-03 Abbott Laboratories Retroviral protease inhibiting compounds
DE69334250D1 (de) * 1992-12-29 2009-01-29 Abbott Lab Verfahren und Intermediate zur Herstellung von retroviralen Proteasehemmern
IL110752A (en) 1993-09-13 2000-07-26 Abbott Lab Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor
US5559158A (en) * 1993-10-01 1996-09-24 Abbott Laboratories Pharmaceutical composition
US5491253A (en) 1993-10-22 1996-02-13 Abbott Laboratories Process for the preparation of a substituted 2,5-diamino-3-hydroxyhexane
IL111991A (en) 1994-01-28 2000-07-26 Abbott Lab Liquid pharmaceutical composition of HIV protease inhibitors in organic solvent
US5567823A (en) * 1995-06-06 1996-10-22 Abbott Laboratories Process for the preparation of an HIV protease inhibiting compound
US6037157A (en) 1995-06-29 2000-03-14 Abbott Laboratories Method for improving pharmacokinetics
US6160122A (en) 1996-06-28 2000-12-12 Abbott Laboratories Process for the preparation of a disubstituted thiazole
ZA9710071B (en) 1996-11-21 1998-05-25 Abbott Lab Pharmaceutical composition.
CO5090830A1 (es) * 1998-07-20 2001-10-30 Abbott Lab Poliformo de un agente farmaceutico
DE19856432A1 (de) * 1998-12-08 2000-06-15 Basf Ag Nanopartikuläre Kern-Schale Systeme sowie deren Verwendung in pharmazeutischen und kosmetischen Zubereitungen
KR100815412B1 (ko) * 1999-06-04 2008-03-20 아보트 러보러터리즈 개선된 약제학적 제형

Also Published As

Publication number Publication date
PL348033A1 (en) 2002-05-06
HU227540B1 (en) 2011-08-29
AU5003799A (en) 2000-02-07
HUP0103823A2 (hu) 2002-02-28
CZ2006533A3 (cs) 2001-05-16
NO318385B1 (no) 2005-03-14
ES2214038T3 (es) 2004-09-01
HU0800267D0 (en) 2008-06-30
SI1097148T1 (en) 2004-10-31
AR059764A2 (es) 2008-04-30
ID27996A (id) 2001-05-03
EP2017269A2 (en) 2009-01-21
NO20042393L (no) 2001-01-18
EP1097148B1 (en) 2004-03-17
PL194710B1 (pl) 2007-06-29
HU230150B1 (hu) 2015-09-28
CA2510949A1 (en) 2000-01-27
PT1418174E (pt) 2009-06-08
CN1310715B (zh) 2010-11-03
EP2298751A2 (en) 2011-03-23
KR20060118022A (ko) 2006-11-17
JP2010270135A (ja) 2010-12-02
NO327320B1 (no) 2009-06-08
SK287586B6 (sk) 2011-03-04
EP2017269A3 (en) 2009-06-10
IL140492A (en) 2010-12-30
CZ298188B6 (cs) 2007-07-18
ES2372990T3 (es) 2012-01-30
EP1418174A2 (en) 2004-05-12
BG109682A (bg) 2007-03-30
TWI271400B (en) 2007-01-21
ATE534636T1 (de) 2011-12-15
CA2337846A1 (en) 2000-01-27
HU229999B1 (en) 2015-04-28
HK1037918A1 (en) 2002-02-22
AR044029A2 (es) 2005-08-24
CA2337846C (en) 2006-02-21
KR100740796B1 (ko) 2007-07-20
DE69915628D1 (en) 2004-04-22
BR9912010A (pt) 2001-04-10
CZ307116B6 (cs) 2018-01-24
PT2017269E (pt) 2011-12-20
CN1502613A (zh) 2004-06-09
KR20010072003A (ko) 2001-07-31
BG65150B1 (bg) 2007-04-30
EP2017269A8 (en) 2009-09-30
MY121765A (en) 2006-02-28
NZ522690A (en) 2004-04-30
HU0800266D0 (en) 2008-06-30
ATE425974T1 (de) 2009-04-15
AR059763A2 (es) 2008-04-30
BG66140B1 (bg) 2011-07-29
EP1097148A2 (en) 2001-05-09
CN101259128A (zh) 2008-09-10
HUP0103823A3 (en) 2003-05-28
AU768207B2 (en) 2003-12-04
TW200716550A (en) 2007-05-01
WO2000004016A2 (en) 2000-01-27
KR100853371B1 (ko) 2008-08-22
BG65963B1 (bg) 2010-07-30
SI2017269T1 (sl) 2012-02-29
AR049658A2 (es) 2006-08-23
CZ2001203A3 (en) 2001-05-16
MY145265A (en) 2012-01-13
DK1418174T3 (da) 2009-05-18
SK286388B6 (sk) 2008-09-05
CA2510949C (en) 2009-11-17
JP5732212B2 (ja) 2015-06-10
BG105197A (en) 2001-10-31
KR20040081137A (ko) 2004-09-20
DE69915628T2 (de) 2004-08-12
NO20010298D0 (no) 2001-01-18
IL187181A (en) 2009-09-01
PL213978B1 (pl) 2013-05-31
EP1418174A3 (en) 2004-06-23
DE69940616D1 (de) 2009-04-30
JP2017061475A (ja) 2017-03-30
CN102153524A (zh) 2011-08-17
CO5090830A1 (es) 2001-10-30
CA2674800A1 (en) 2000-01-27
CY1112139T1 (el) 2015-11-04
TWI227713B (en) 2005-02-11
JP4815050B2 (ja) 2011-11-16
CY1111600T1 (el) 2015-10-07
KR100793046B1 (ko) 2008-01-10
SK922001A3 (en) 2001-07-10
CN1310715A (zh) 2001-08-29
TR200100171T2 (tr) 2001-05-21
EP2298751A3 (en) 2011-08-17
EP2017269B1 (en) 2011-11-23
IL187181A0 (en) 2008-02-09
SI1418174T1 (sl) 2009-08-31
JP2014074047A (ja) 2014-04-24
EP1418174B1 (en) 2009-03-18
EP2017269A9 (en) 2009-10-14
IL191582A (en) 2016-02-29
AR019431A1 (es) 2002-02-20
DK2017269T3 (da) 2012-03-05
HK1121155A1 (en) 2009-04-17
TWI362382B (en) 2012-04-21
CN101966180A (zh) 2011-02-09
NO20010298L (no) 2001-01-18
ES2322759T3 (es) 2009-06-26
WO2000004016A3 (en) 2000-03-30
SK287381B6 (sk) 2010-08-09
IL191582A0 (en) 2008-12-29
NZ509125A (en) 2003-02-28
JP2002520410A (ja) 2002-07-09
DK1097148T3 (da) 2004-04-26
IL140492A0 (en) 2002-02-10
BG110080A (bg) 2008-11-28
ATE261947T1 (de) 2004-04-15

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