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HK1019003A1 - Use of 2-amino-6-a-propylamino-4,5,6,7- tetrahydrobenzothiazole(pram ipexol) as an anti-depressant drug - Google Patents

Use of 2-amino-6-a-propylamino-4,5,6,7- tetrahydrobenzothiazole(pram ipexol) as an anti-depressant drug

Info

Publication number
HK1019003A1
HK1019003A1 HK98113329A HK98113329A HK1019003A1 HK 1019003 A1 HK1019003 A1 HK 1019003A1 HK 98113329 A HK98113329 A HK 98113329A HK 98113329 A HK98113329 A HK 98113329A HK 1019003 A1 HK1019003 A1 HK 1019003A1
Authority
HK
Hong Kong
Prior art keywords
ipexol
tetrahydrobenzothiazole
pram
propylamino
amino
Prior art date
Application number
HK98113329A
Other languages
English (en)
Inventor
Franco Borsini
Rudolf Hammer
Joachim Mierau
Erich Lehr
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of HK1019003A1 publication Critical patent/HK1019003A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
HK98113329A 1992-12-05 1998-12-14 Use of 2-amino-6-a-propylamino-4,5,6,7- tetrahydrobenzothiazole(pram ipexol) as an anti-depressant drug HK1019003A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4241013A DE4241013A1 (de) 1992-12-05 1992-12-05 Verwendung von 2-Amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol als Arzneimittel mit antidepressiver Wirkung
PCT/EP1993/003389 WO1994013287A1 (de) 1992-12-05 1993-12-02 Verwendung von 2-amino-6-a-propyl-amino-4,5,6,7-tetrahydrobenzothiazol (pramipexol) als arzneimittel mit antidepressiver wirkung

Publications (1)

Publication Number Publication Date
HK1019003A1 true HK1019003A1 (en) 2000-01-14

Family

ID=6474503

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98113329A HK1019003A1 (en) 1992-12-05 1998-12-14 Use of 2-amino-6-a-propylamino-4,5,6,7- tetrahydrobenzothiazole(pram ipexol) as an anti-depressant drug

Country Status (29)

Country Link
US (1) US6191153B1 (xx)
EP (1) EP0675717B1 (xx)
JP (1) JP3221880B2 (xx)
KR (1) KR100311165B1 (xx)
CN (1) CN1052400C (xx)
AT (1) ATE183091T1 (xx)
AU (1) AU674378B2 (xx)
BG (1) BG62475B1 (xx)
CA (1) CA2150131C (xx)
CZ (1) CZ282679B6 (xx)
DE (2) DE4241013A1 (xx)
DK (1) DK0675717T3 (xx)
ES (1) ES2136725T3 (xx)
FI (1) FI952734A0 (xx)
GR (1) GR3031521T3 (xx)
HK (1) HK1019003A1 (xx)
HU (1) HU221014B1 (xx)
IL (1) IL107870A (xx)
MX (1) MX9307644A (xx)
NO (1) NO306930B1 (xx)
NZ (1) NZ258876A (xx)
PL (1) PL309282A1 (xx)
RU (1) RU2157685C2 (xx)
SG (1) SG49228A1 (xx)
SK (1) SK281441B6 (xx)
TW (1) TW362973B (xx)
UA (1) UA35604C2 (xx)
WO (1) WO1994013287A1 (xx)
ZA (1) ZA939065B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6156777A (en) 1994-12-15 2000-12-05 Pharmacia & Upjohn Company Use of pramipexole as a neuroprotective agent
US5650420A (en) * 1994-12-15 1997-07-22 Pharmacia & Upjohn Company Pramipexole as a neuroprotective agent
US6001861A (en) * 1998-01-16 1999-12-14 Pharmacia & Upjohn Company Use of pramipexole in the treatment of restless legs syndrome
DE19830201A1 (de) * 1998-07-07 2000-01-13 Boehringer Ingelheim Pharma Mittel mit antidepressiver Wirkung
CA2301899C (en) * 1998-07-27 2008-11-18 Boehringer Ingelheim Pharma Kg Agent with an antidepressant activity
PE20011074A1 (es) 2000-02-23 2001-10-04 Upjohn Co Uso de pramipexol en el tratamiento de trastornos de adiccion
CA2415815A1 (en) * 2000-07-06 2002-01-17 Nigel H. Greig Tetrahydrobenzothiazole analogues as neuroprotective agents
WO2002069974A1 (en) * 2001-03-05 2002-09-12 Andrew Holman Administration of sleep restorative agents
EP1260221A3 (en) * 2001-05-23 2002-12-18 Pfizer Products Inc. Combination treatment for depression and anxiety
DE10138275A1 (de) * 2001-08-10 2003-02-27 Boehringer Ingelheim Pharma Verbindungen zur Beseitigung der Anhedonie
PA8578501A1 (es) * 2002-07-25 2005-02-04 Pharmacia Corp Forma de dosificacion una vez al dia de pramipexol
DE102004006808A1 (de) * 2004-02-11 2005-09-01 Grünenthal GmbH Substituierte 4,5,6,7-Tetrahydro-benzothiazol-2-ylamin-Verbindungen
EP2286801A3 (en) * 2004-08-13 2012-05-09 Boehringer Ingelheim International GmbH Extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof
JP4971159B2 (ja) * 2004-08-13 2012-07-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング プラミペキソール又はその薬学的に許容しうる塩を含有する徐放性ペレット製剤、その製法及び使用
RU2413510C2 (ru) * 2005-04-04 2011-03-10 Такеда Фармасьютикал Компани Лимитед Профилактический или терапевтический агент против депрессии или тревожного расстройства
US20080262053A1 (en) * 2005-10-18 2008-10-23 Juergen Reess Use of Pramipexole for Treating Moderate to Severe Restless Legs Syndrome (Rls)
JP2009526021A (ja) * 2006-02-10 2009-07-16 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 放出を加減した製剤
US20090098202A1 (en) * 2006-02-10 2009-04-16 Boehringer Ingelheim International Gmbh Extended Release Formulation
KR20200002899A (ko) * 2017-04-10 2020-01-08 체이스 테라퓨틱스 코포레이션 시누클레인병변을 치료하기 위한 nk1-길항제 배합물 및 방법
CN111032158A (zh) 2017-06-30 2020-04-17 才思治疗公司 用于治疗抑郁的nk-1拮抗剂组合物和方法
CN108802584B (zh) * 2018-06-29 2020-12-08 广东工业大学 一种变压器绝缘纸老化状态评估方法
TWI672472B (zh) * 2018-08-15 2019-09-21 鄭映芳 飲料製冰機裝置
CN110028464B (zh) * 2019-04-26 2022-11-18 浙江海洋大学 一种南极真菌次级代谢衍生物BTZ-one及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0186087B1 (de) * 1984-12-22 1989-08-23 Dr. Karl Thomae GmbH Tetrahydro-benzthiazole, deren Herstellung und deren Verwendung als Zwischenprodukte oder als Arnzneimittel
DE3843227A1 (de) * 1988-12-22 1990-07-05 Boehringer Ingelheim Kg Neue verwendung von 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzthiazol
DE3930282A1 (de) * 1989-09-11 1991-03-21 Boehringer Ingelheim Kg Verwendung von dopamin-autorezeptor-agonisten bei der behandlung von drogenabhaengigkeit

Also Published As

Publication number Publication date
DE59309733D1 (de) 1999-09-16
KR950703953A (ko) 1995-11-17
CZ144095A3 (en) 1996-03-13
IL107870A (en) 1996-12-05
CN1052400C (zh) 2000-05-17
EP0675717A1 (de) 1995-10-11
HU9501623D0 (en) 1995-08-28
PL309282A1 (en) 1995-10-02
DE4241013A1 (de) 1994-06-09
KR100311165B1 (ko) 2001-12-28
JP3221880B2 (ja) 2001-10-22
CN1091635A (zh) 1994-09-07
BG62475B1 (bg) 1999-12-30
WO1994013287A1 (de) 1994-06-23
NZ258876A (en) 1997-07-27
FI952734A (fi) 1995-06-05
NO306930B1 (no) 2000-01-17
FI952734A0 (fi) 1995-06-05
MX9307644A (es) 1994-06-30
JPH08504201A (ja) 1996-05-07
SG49228A1 (en) 1998-05-18
CA2150131A1 (en) 1994-06-23
NO952207L (no) 1995-06-02
TW362973B (en) 1999-07-01
ZA939065B (en) 1994-08-04
AU5715294A (en) 1994-07-04
IL107870A0 (en) 1994-04-12
DK0675717T3 (da) 2000-02-28
NO952207D0 (no) 1995-06-02
CA2150131C (en) 2004-09-21
ES2136725T3 (es) 1999-12-01
SK74095A3 (en) 1996-05-08
US6191153B1 (en) 2001-02-20
RU2157685C2 (ru) 2000-10-20
UA35604C2 (uk) 2001-04-16
SK281441B6 (sk) 2001-03-12
HU221014B1 (hu) 2002-07-29
AU674378B2 (en) 1996-12-19
HUT71798A (en) 1996-02-28
ATE183091T1 (de) 1999-08-15
GR3031521T3 (en) 2000-01-31
CZ282679B6 (cs) 1997-08-13
EP0675717B1 (de) 1999-08-11
BG99700A (bg) 1996-04-30

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Effective date: 20131201