HK1086270A1 - Benzothiazole derivative compounds, compositions and uses - Google Patents

Benzothiazole derivative compounds, compositions and uses

Info

Publication number: HK1086270A1
Authority: HK; Hong Kong
Prior art keywords: compositions; derivative compounds; benzothiazole derivative; benzothiazole; compounds
Prior art date: 2003-03-14

Application number

HK06107502.0A

Other languages

English (en)

Inventor

William E Klunk

Jr Chester A Mathis

Yanming Wang

Original Assignee

Univ Pittsburgh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-03-14

Filing date

2006-07-04

Publication date

2006-09-15

2003-03-14 Priority claimed from US10/388,173 external-priority patent/US7270800B2/en

2003-08-22 Priority claimed from US10/645,847 external-priority patent/US20050043523A1/en

2004-03-15 Priority claimed from PCT/US2004/007797 external-priority patent/WO2004083195A1/en

2006-07-04 Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh

2006-09-15 Publication of HK1086270A1 publication Critical patent/HK1086270A1/xx

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
- C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
General Physics & Mathematics (AREA)
Cell Biology (AREA)
Food Science & Technology (AREA)
Biotechnology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Pathology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Magnetic Resonance Imaging Apparatus (AREA)
Thiazole And Isothizaole Compounds (AREA)

HK06107502.0A 2003-03-14 2006-07-04 Benzothiazole derivative compounds, compositions and uses HK1086270A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US10/388,173 US7270800B2 (en)	2000-08-24	2003-03-14	Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
US10/645,847 US20050043523A1 (en)	2003-08-22	2003-08-22	Benzothiazole derivative compounds, compositions and uses
PCT/US2004/007797 WO2004083195A1 (en)	2003-03-14	2004-03-15	Benzothiazole derivative compounds, compositions and uses

Publications (1)

Publication Number	Publication Date
HK1086270A1 true HK1086270A1 (en)	2006-09-15

Family

ID=35057877

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK06107502.0A HK1086270A1 (en)	2003-03-14	2006-07-04	Benzothiazole derivative compounds, compositions and uses

Country Status (16)

Country	Link
EP (1)	EP1611115B1 (no)
JP (1)	JP4875487B2 (no)
CN (2)	CN102532055B (no)
AU (2)	AU2004221897B2 (no)
BE (1)	BE2015C005I2 (no)
BR (1)	BRPI0408274B8 (no)
CY (2)	CY1113334T1 (no)
DK (1)	DK1611115T3 (no)
ES (1)	ES2393921T3 (no)
HK (1)	HK1086270A1 (no)
HU (1)	HUS1500006I1 (no)
NO (3)	NO330861B1 (no)
PL (1)	PL1611115T3 (no)
PT (1)	PT1611115E (no)
RU (1)	RU2440995C2 (no)
SI (1)	SI1611115T1 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1285582C (zh)	2000-08-24	2006-11-22	匹兹堡大学	用于早老性痴呆的死前诊断和淀粉样蛋白沉积的体内成象和预防的硫黄素衍生物
US7270800B2 (en)	2000-08-24	2007-09-18	University Of Pittsburgh	Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
BRPI0510142A (pt) *	2004-05-20	2007-10-02	Foldrx Pharmaceuticals Inc	compostos, composições e métodos para estabilizar a transtiretina e inibir a duplicação defeituosa da transtiretina
GB0516564D0 (en) *	2005-08-12	2005-09-21	Ge Healthcare Ltd	Fluorination process
RU2494669C2 (ru) *	2007-01-30	2013-10-10	Джи-И Хелткер Лимитед	Средства диагностики нейродегенеративных заболеваний
CN101293878B (zh) *	2007-04-25	2010-12-15	中国科学院上海应用物理研究所	苯并噻唑苯胺类化合物及其制备方法和应用
WO2010011964A2 (en) *	2008-07-24	2010-01-28	Siemens Medical Solutions Usa, Inc.	Imaging agents useful for identifying ad pathology
MX2011002647A (es) *	2008-09-23	2011-04-07	Wista Lab Ltd	Ligandos para moleculas tau agregadas.
CN105579453B (zh)	2013-09-26	2017-12-22	豪夫迈·罗氏有限公司	作为成像工具的咪唑并[1，2‑a]吡啶‑7‑胺类
JP6260967B2 (ja) *	2013-11-06	2018-01-17	国立大学法人京都大学	放射性ヨウ素標識化合物、及び、これを含む放射性医薬
CN103613589B (zh) *	2013-11-29	2016-03-30	江苏华益科技有限公司	一种用于神经退行性疾病领域的新型pet显像剂前体及标准品的合成方法
CN107105655A (zh) *	2014-08-29	2017-08-29	Chdi基金会股份有限公司	用于成像亨廷顿蛋白的探针
CN109400615B (zh) *	2017-08-18	2021-07-16	上海交通大学医学院附属新华医院	一种靶向β-淀粉样蛋白的香豆素类化合物及其制备与应用
GR1009516B (el) *	2018-03-22	2019-05-02	Εκεφε Δημοκριτος	Τρικαρβονυλο-συμπλοκα μεταλλων μεταπτωσεως με βενζο-ετεροκυκλικο παραγωγο του κυκλοπενταδιενυλικου ανιοντος με υψηλη διαπερατοτητα του αιματοεγκεφαλικου φραγμου για εφαρμογες στη διαγνωση και θεραπεια νοσων του κνς

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998022493A2 (en) *	1996-11-22	1998-05-28	Elan Pharmaceuticals, Inc.	N-(ARYL/HETEROARYL) AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS
GB9919673D0 (en) *	1999-08-20	1999-10-20	Cancer Res Campaign Tech	2-Arlybenzazole compounds
CN1285582C (zh) *	2000-08-24	2006-11-22	匹兹堡大学	用于早老性痴呆的死前诊断和淀粉样蛋白沉积的体内成象和预防的硫黄素衍生物
WO2002051821A1 (en) *	2000-12-22	2002-07-04	Astrazeneca Ab	Therapeutic compounds
JP4317955B2 (ja) *	2001-04-23	2009-08-19	ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア	アミロイド斑凝集阻害剤および診断用造影剤
GB0229686D0 (en) *	2002-12-20	2003-01-29	Amersham Plc	Solid-phase fluorination of benzothiazoles

2004
- 2004-03-15 SI SI200431952T patent/SI1611115T1/sl unknown
- 2004-03-15 ES ES04720788T patent/ES2393921T3/es not_active Expired - Lifetime
- 2004-03-15 JP JP2006507179A patent/JP4875487B2/ja not_active Expired - Lifetime
- 2004-03-15 RU RU2005131872/04A patent/RU2440995C2/ru not_active Application Discontinuation
- 2004-03-15 CN CN201110437182.5A patent/CN102532055B/zh not_active Expired - Lifetime
- 2004-03-15 EP EP04720788A patent/EP1611115B1/en not_active Expired - Lifetime
- 2004-03-15 PL PL04720788T patent/PL1611115T3/pl unknown
- 2004-03-15 PT PT47207881T patent/PT1611115E/pt unknown
- 2004-03-15 CN CNA2004800125035A patent/CN1784392A/zh active Pending
- 2004-03-15 DK DK04720788.1T patent/DK1611115T3/da active
- 2004-03-15 AU AU2004221897A patent/AU2004221897B2/en not_active Expired
- 2004-03-15 BR BRPI0408274A patent/BRPI0408274B8/pt active IP Right Grant
2005
- 2005-10-11 NO NO20054674A patent/NO330861B1/no active Protection Beyond IP Right Term
2006
- 2006-07-04 HK HK06107502.0A patent/HK1086270A1/xx not_active IP Right Cessation
2011
- 2011-02-16 AU AU2011200667A patent/AU2011200667B2/en not_active Expired
- 2011-07-06 NO NO20110980A patent/NO20110980L/no not_active Application Discontinuation
2012
- 2012-11-16 CY CY20121101106T patent/CY1113334T1/el unknown
2015
- 2015-01-27 BE BE2015C005C patent/BE2015C005I2/fr unknown
- 2015-02-18 NO NO2015005C patent/NO2015005I1/no not_active IP Right Cessation
- 2015-02-18 HU HUS1500006C patent/HUS1500006I1/hu unknown
- 2015-03-04 CY CY2015007C patent/CY2015007I1/el unknown

Also Published As

Publication number	Publication date
AU2004221897A2 (en)	2004-09-30
CN102532055A (zh)	2012-07-04
JP2006522104A (ja)	2006-09-28
AU2011200667A1 (en)	2011-03-10
NO2015005I2 (no)	2015-02-18
PT1611115E (pt)	2012-12-07
NO20054674L (no)	2005-12-13
PL1611115T3 (pl)	2013-01-31
CN102532055B (zh)	2016-05-11
NO20110980L (no)	2005-12-13
AU2004221897A1 (en)	2004-09-30
NO20054674D0 (no)	2005-10-11
CY1113334T1 (el)	2015-12-09
ES2393921T3 (es)	2013-01-02
RU2440995C2 (ru)	2012-01-27
BRPI0408274B1 (pt)	2019-02-26
CN1784392A (zh)	2006-06-07
DK1611115T3 (da)	2012-11-26
NO330861B1 (no)	2011-08-01
JP4875487B2 (ja)	2012-02-15
RU2005131872A (ru)	2006-02-27
NO2015005I1 (no)	2015-03-02
BRPI0408274B8 (pt)	2021-05-25
AU2004221897A9 (en)	2009-08-20
AU2004221897B2 (en)	2010-11-18
AU2011200667B2 (en)	2011-12-22
HUS1500006I1 (hu)	2015-02-18
BRPI0408274A (pt)	2006-03-21
EP1611115A1 (en)	2006-01-04
SI1611115T1 (sl)	2012-12-31
CY2015007I1 (el)	2015-12-09
BE2015C005I2 (no)	2023-03-07
EP1611115B1 (en)	2012-08-22

Publication	Publication Date	Title
HUS1500006I1 (hu)	2015-02-18	Benzotiazol-származék vegyületek, kompozíciók és alkalmazások
EP1646382A4 (en)	2010-07-21	COMPOUNDS, COMPOSITIONS AND METHODS
EP1692112A4 (en)	2008-09-24	COMPOUNDS, COMPOSITIONS, AND METHODS
ZA200606027B (en)	2021-04-28	Thiazole derivative
AU2003262747A8 (en)	2004-03-11	Compounds, compositions, and methods
EP1503993A4 (en)	2006-05-03	COMPOUNDS, METHODS AND COMPOSITIONS
AU2003236527A8 (en)	2003-12-31	Compounds, compositions, and methods
AU2003265242A8 (en)	2003-12-22	Compounds, compositions, and methods
IL175300A0 (en)	2006-09-05	Indirubin-type compounds, compositions, and methods for their use
AU2003270015A8 (en)	2003-12-02	Compounds, compositions, and methods
AU2003299612A8 (en)	2004-07-09	Compounds, compositions and methods
HK1070656A1 (en)	2005-06-24	Compounds, compositions, and methods
PL374833A1 (en)	2005-10-31	5-aryltetrazole compounds, compositions thereof, and uses therefor
IL167936A0 (en)	2009-02-11	Compounds, compositions,and methods
AU2003290507A8 (en)	2004-04-08	Compounds, compositions and methods
EP1675834A4 (en)	2008-08-27	COMPOUNDS, COMPOSITIONS AND METHODS
AU2003277079A8 (en)	2004-05-04	Compounds, compositions, and methods
EP1594849A4 (en)	2007-07-04	COMPOUNDS, COMPOSITIONS, AND METHODS
EP1680420A4 (en)	2008-09-24	COMPOUNDS, COMPOSITIONS AND METHODS
GB0307695D0 (en)	2003-05-07	Compounds,compositions and processes
EP1620092A4 (en)	2008-04-16	COMPOUNDS, COMPOSITIONS AND METHODS
AU2003267169A8 (en)	2004-04-30	Compounds, compositions and methods
AU2003300031A8 (en)	2004-05-04	Compounds, compositions, and methods
EP1706111A4 (en)	2009-03-04	COMPOUNDS, COMPOSITIONS AND METHODS
EP1593684A4 (en)	2010-06-02	NEW COMPOUND CALL CAPRAZENE AND DERIVATIVES THEREOF AND NOVEL COMPOUND CALL CAPRAZOL AND DERIVATIVES THEREOF

Legal Events

Date	Code	Title	Description
2024-03-28	PE	Patent expired	Effective date: 20240314