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BE2015C005I2 - - Google Patents

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Publication number
BE2015C005I2
BE2015C005I2 BE2015C005C BE2015C005C BE2015C005I2 BE 2015C005 I2 BE2015C005 I2 BE 2015C005I2 BE 2015C005 C BE2015C005 C BE 2015C005C BE 2015C005 C BE2015C005 C BE 2015C005C BE 2015C005 I2 BE2015C005 I2 BE 2015C005I2
Authority
BE
Belgium
Application number
BE2015C005C
Original Assignee
Univ Pittsburgh Commonwealth Sys Higher Education
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/388,173 external-priority patent/US7270800B2/en
Priority claimed from US10/645,847 external-priority patent/US20050043523A1/en
Application filed by Univ Pittsburgh Commonwealth Sys Higher Education filed Critical Univ Pittsburgh Commonwealth Sys Higher Education
Publication of BE2015C005I2 publication Critical patent/BE2015C005I2/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
BE2015C005C 2003-03-14 2015-01-27 BE2015C005I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/388,173 US7270800B2 (en) 2000-08-24 2003-03-14 Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
US10/645,847 US20050043523A1 (en) 2003-08-22 2003-08-22 Benzothiazole derivative compounds, compositions and uses

Publications (1)

Publication Number Publication Date
BE2015C005I2 true BE2015C005I2 (fr) 2023-03-07

Family

ID=35057877

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2015C005C BE2015C005I2 (fr) 2003-03-14 2015-01-27

Country Status (16)

Country Link
EP (1) EP1611115B1 (fr)
JP (1) JP4875487B2 (fr)
CN (2) CN102532055B (fr)
AU (2) AU2004221897B2 (fr)
BE (1) BE2015C005I2 (fr)
BR (1) BRPI0408274B8 (fr)
CY (2) CY1113334T1 (fr)
DK (1) DK1611115T3 (fr)
ES (1) ES2393921T3 (fr)
HK (1) HK1086270A1 (fr)
HU (1) HUS1500006I1 (fr)
NO (3) NO330861B1 (fr)
PL (1) PL1611115T3 (fr)
PT (1) PT1611115E (fr)
RU (1) RU2440995C2 (fr)
SI (1) SI1611115T1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1285582C (zh) 2000-08-24 2006-11-22 匹兹堡大学 用于早老性痴呆的死前诊断和淀粉样蛋白沉积的体内成象和预防的硫黄素衍生物
US7270800B2 (en) 2000-08-24 2007-09-18 University Of Pittsburgh Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
BRPI0510142A (pt) * 2004-05-20 2007-10-02 Foldrx Pharmaceuticals Inc compostos, composições e métodos para estabilizar a transtiretina e inibir a duplicação defeituosa da transtiretina
GB0516564D0 (en) * 2005-08-12 2005-09-21 Ge Healthcare Ltd Fluorination process
RU2494669C2 (ru) * 2007-01-30 2013-10-10 Джи-И Хелткер Лимитед Средства диагностики нейродегенеративных заболеваний
CN101293878B (zh) * 2007-04-25 2010-12-15 中国科学院上海应用物理研究所 苯并噻唑苯胺类化合物及其制备方法和应用
WO2010011964A2 (fr) * 2008-07-24 2010-01-28 Siemens Medical Solutions Usa, Inc. Agents d'imagerie utiles pour identifier une pathologie
MX2011002647A (es) * 2008-09-23 2011-04-07 Wista Lab Ltd Ligandos para moleculas tau agregadas.
CN105579453B (zh) 2013-09-26 2017-12-22 豪夫迈·罗氏有限公司 作为成像工具的咪唑并[1，2‑a]吡啶‑7‑胺类
JP6260967B2 (ja) * 2013-11-06 2018-01-17 国立大学法人京都大学 放射性ヨウ素標識化合物、及び、これを含む放射性医薬
CN103613589B (zh) * 2013-11-29 2016-03-30 江苏华益科技有限公司 一种用于神经退行性疾病领域的新型pet显像剂前体及标准品的合成方法
CN107105655A (zh) * 2014-08-29 2017-08-29 Chdi基金会股份有限公司 用于成像亨廷顿蛋白的探针
CN109400615B (zh) * 2017-08-18 2021-07-16 上海交通大学医学院附属新华医院 一种靶向β-淀粉样蛋白的香豆素类化合物及其制备与应用
GR1009516B (el) * 2018-03-22 2019-05-02 Εκεφε Δημοκριτος Τρικαρβονυλο-συμπλοκα μεταλλων μεταπτωσεως με βενζο-ετεροκυκλικο παραγωγο του κυκλοπενταδιενυλικου ανιοντος με υψηλη διαπερατοτητα του αιματοεγκεφαλικου φραγμου για εφαρμογες στη διαγνωση και θεραπεια νοσων του κνς

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998022493A2 (fr) * 1996-11-22 1998-05-28 Elan Pharmaceuticals, Inc. DERIVES DE N-(ARYL/HETEROARYL) AMINOACIDE, COMPOSITIONS PHARMACEUTIQUES LES CONTENANT ET PROCEDES PERMETTANT D'INHIBER LA LIBERATION DE PEPTIDE β AMYLOIDE ET/OU SA SYNTHESE A L'AIDE DE CES COMPOSES
GB9919673D0 (en) * 1999-08-20 1999-10-20 Cancer Res Campaign Tech 2-Arlybenzazole compounds
CN1285582C (zh) * 2000-08-24 2006-11-22 匹兹堡大学 用于早老性痴呆的死前诊断和淀粉样蛋白沉积的体内成象和预防的硫黄素衍生物
WO2002051821A1 (fr) * 2000-12-22 2002-07-04 Astrazeneca Ab Composes therapeutiques
JP4317955B2 (ja) * 2001-04-23 2009-08-19 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア アミロイド斑凝集阻害剤および診断用造影剤
GB0229686D0 (en) * 2002-12-20 2003-01-29 Amersham Plc Solid-phase fluorination of benzothiazoles

Also Published As

Publication number Publication date
AU2004221897A2 (en) 2004-09-30
CN102532055A (zh) 2012-07-04
JP2006522104A (ja) 2006-09-28
AU2011200667A1 (en) 2011-03-10
NO2015005I2 (no) 2015-02-18
PT1611115E (pt) 2012-12-07
NO20054674L (no) 2005-12-13
PL1611115T3 (pl) 2013-01-31
CN102532055B (zh) 2016-05-11
NO20110980L (no) 2005-12-13
AU2004221897A1 (en) 2004-09-30
NO20054674D0 (no) 2005-10-11
CY1113334T1 (el) 2015-12-09
ES2393921T3 (es) 2013-01-02
RU2440995C2 (ru) 2012-01-27
BRPI0408274B1 (pt) 2019-02-26
CN1784392A (zh) 2006-06-07
HK1086270A1 (en) 2006-09-15
DK1611115T3 (da) 2012-11-26
NO330861B1 (no) 2011-08-01
JP4875487B2 (ja) 2012-02-15
RU2005131872A (ru) 2006-02-27
NO2015005I1 (no) 2015-03-02
BRPI0408274B8 (pt) 2021-05-25
AU2004221897A9 (en) 2009-08-20
AU2004221897B2 (en) 2010-11-18
AU2011200667B2 (en) 2011-12-22
HUS1500006I1 (hu) 2015-02-18
BRPI0408274A (pt) 2006-03-21
EP1611115A1 (fr) 2006-01-04
SI1611115T1 (sl) 2012-12-31
CY2015007I1 (el) 2015-12-09
EP1611115B1 (fr) 2012-08-22

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