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GR3034910T3 - Pyridazinone derivatives and processes for preparing the same - Google Patents

Pyridazinone derivatives and processes for preparing the same

Info

Publication number
GR3034910T3
GR3034910T3 GR20000402616T GR20000402616T GR3034910T3 GR 3034910 T3 GR3034910 T3 GR 3034910T3 GR 20000402616 T GR20000402616 T GR 20000402616T GR 20000402616 T GR20000402616 T GR 20000402616T GR 3034910 T3 GR3034910 T3 GR 3034910T3
Authority
GR
Greece
Prior art keywords
preparing
processes
same
pyridazinone derivatives
pyridazinone
Prior art date
Application number
GR20000402616T
Other languages
English (en)
Inventor
Akihiko Ishida
Harutami Yamada
Michihisa Yato
Shinsuke Nishiyama
Fumikazu Okumura
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of GR3034910T3 publication Critical patent/GR3034910T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Optical Couplings Of Light Guides (AREA)
GR20000402616T 1995-06-27 2000-11-24 Pyridazinone derivatives and processes for preparing the same GR3034910T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP16062095 1995-06-27
JP1985996 1996-02-06

Publications (1)

Publication Number Publication Date
GR3034910T3 true GR3034910T3 (en) 2001-02-28

Family

ID=26356726

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000402616T GR3034910T3 (en) 1995-06-27 2000-11-24 Pyridazinone derivatives and processes for preparing the same

Country Status (21)

Country Link
US (2) US5698554A (el)
EP (1) EP0751132B1 (el)
KR (1) KR970061873A (el)
CN (1) CN1144802A (el)
AR (1) AR002602A1 (el)
AT (1) ATE195937T1 (el)
AU (1) AU694955B2 (el)
BG (1) BG62768B1 (el)
CA (1) CA2179939A1 (el)
DE (1) DE69610036T2 (el)
DK (1) DK0751132T3 (el)
ES (1) ES2151110T3 (el)
GR (1) GR3034910T3 (el)
HU (1) HUP9601766A3 (el)
IL (1) IL118631A (el)
MY (1) MY132263A (el)
NO (1) NO311084B1 (el)
PT (1) PT751132E (el)
RU (1) RU2131419C1 (el)
SG (1) SG46741A1 (el)
TW (1) TW432052B (el)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2235911C (en) * 1997-05-27 2003-07-29 Schneider (Usa) Inc. Stent and stent-graft for treating branched vessels
KR20030061051A (ko) * 2002-01-07 2003-07-18 대한민국 (경상대학교 총장) 신규한 아렌(혹은 알케인)술폰일피리다진온 유도체, 이의제조방법 및 유기반응에서의 용도
AR050552A1 (es) * 2004-09-02 2006-11-01 Osi Pharm Inc Mercaptoamidas como inhibidores de histona desacetilasa
ZA200807796B (en) * 2006-03-17 2009-12-30 Sumitomo Chemical Co Pyridazinone compound and use thereof as herbicides
EA017004B1 (ru) * 2006-07-25 2012-09-28 Сефалон, Инк. Пиридизиноновые производные
EP2220073B1 (en) * 2007-11-15 2014-09-03 MSD Italia S.r.l. Pyridazinone derivatives as parp inhibitors
US9062057B2 (en) 2010-03-19 2015-06-23 Purdue Research Foundation CCR5 antagonists for treating HIV
EP2635572B1 (en) 2010-11-05 2018-10-17 Senomyx, Inc. Compounds useful as modulators of trpm8
MX2013015058A (es) 2011-06-24 2014-01-20 Amgen Inc Antagonistas de melastatina 8 de potencial receptor transitorio y su uso en tratamientos.
JP2014527511A (ja) 2011-06-24 2014-10-16 アムジエン・インコーポレーテツド Trpm8拮抗剤及び治療におけるそれらの使用
WO2013097052A1 (en) 2011-12-30 2013-07-04 Abbott Laboratories Bromodomain inhibitors
US8952009B2 (en) 2012-08-06 2015-02-10 Amgen Inc. Chroman derivatives as TRPM8 inhibitors
CN108473484B (zh) 2015-10-01 2021-06-29 弗门尼舍公司 可用作trpm8调节剂的化合物
MY190795A (en) 2016-04-15 2022-05-12 Abbvie Inc Bromodomain inhibitors
CA3116931A1 (en) * 2018-10-30 2020-05-07 Nuvation Bio Inc. Heterocyclic compounds as bet inhibitors
HUE063586T2 (hu) 2018-11-06 2024-01-28 Edgewise Therapeutics Inc Piridazinon-vegyületek és alkalmazásaik
CN114286818B (zh) 2019-07-02 2024-09-20 诺维逊生物股份有限公司 作为bet抑制剂的杂环化合物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6053022B2 (ja) 1977-04-07 1985-11-22 ウェルファイド株式会社 ピリダジノン誘導体
GB8323553D0 (en) * 1983-09-02 1983-10-05 Smith Kline French Lab Pharmaceutical compositions
JPS6193169A (ja) * 1984-10-12 1986-05-12 Sankyo Co Ltd ピリダジノン誘導体及びその製法
KR860007219A (ko) * 1985-03-12 1986-10-08 베쩰, 좀머 설포닐아미노에틸 화합물의 제조방법
EP0194548A3 (de) * 1985-03-12 1988-08-17 Dr. Karl Thomae GmbH Neue Sulfonylaminoäthylverbindungen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE3508692A1 (de) 1985-03-12 1986-09-18 Dr. Karl Thomae Gmbh, 7950 Biberach 3-(4-(2-benzolsulfonylamino-aethyl)-benzoyl)propionsaeure, diese verbindung enthaltende arzneimittel und verfahren zu ihrer herstellung
DE3623944A1 (de) 1986-07-16 1988-02-11 Thomae Gmbh Dr K Neue benzolsulfonamido-indanylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
JPS63145272A (ja) * 1986-12-09 1988-06-17 Morishita Seiyaku Kk 4,5−ジヒドロ−6−(4−置換フエニル)−3(2h)−ピリダジノン誘導体
DE3728491A1 (de) * 1987-08-26 1989-03-09 Heumann Pharma Gmbh & Co Dihydropyridazinon-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE4134467A1 (de) * 1991-10-18 1993-04-22 Thomae Gmbh Dr K Heterobiarylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
EP0589037B1 (en) * 1991-03-01 1996-05-29 Zeria Pharmaceutical Co., Ltd. Indian derivative and thromboxane antagonist containing the same
CA2099743A1 (en) * 1992-07-02 1994-01-03 Akihiko Ishida Pyridazinone derivatives and processes for preparing the same
JP2616584B2 (ja) * 1992-07-02 1997-06-04 田辺製薬株式会社 ピリダジノン誘導体及びその製法
JP2757353B2 (ja) * 1993-12-28 1998-05-25 田辺製薬株式会社 インダン誘導体、その製法及びその合成中間体
CA2139088A1 (en) * 1993-12-28 1995-06-29 Akihiko Ishida Indane derivatives, processes for preparing the same and synthetic intermediate of the same
CA2138812A1 (en) * 1993-12-28 1995-06-29 Akihiko Ishida Indane derivative and processes for preparing the same

Also Published As

Publication number Publication date
ES2151110T3 (es) 2000-12-16
RU2131419C1 (ru) 1999-06-10
BG100684A (bg) 1997-03-31
NO311084B1 (no) 2001-10-08
ATE195937T1 (de) 2000-09-15
NO962643D0 (no) 1996-06-21
MY132263A (en) 2007-09-28
NO962643L (no) 1996-12-30
DE69610036T2 (de) 2001-04-12
DK0751132T3 (da) 2000-11-13
US5808065A (en) 1998-09-15
HUP9601766A3 (en) 1998-04-28
IL118631A0 (en) 1996-10-16
CN1144802A (zh) 1997-03-12
HUP9601766A2 (en) 1997-02-28
EP0751132B1 (en) 2000-08-30
US5698554A (en) 1997-12-16
TW432052B (en) 2001-05-01
IL118631A (en) 2002-05-23
AR002602A1 (es) 1998-03-25
AU694955B2 (en) 1998-08-06
AU5622196A (en) 1997-01-09
PT751132E (pt) 2000-12-29
KR970061873A (ko) 1997-09-12
DE69610036D1 (de) 2000-10-05
SG46741A1 (en) 1998-02-20
EP0751132A1 (en) 1997-01-02
HU9601766D0 (en) 1996-08-28
CA2179939A1 (en) 1996-12-28
BG62768B1 (bg) 2000-07-31

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Legal Events

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