GC0000112A - Pyrazolopyridines, their preparation, pharmaceutical compositions containing them and their use in medicine (pyrazolopyridine derivatives). - Google Patents

Pyrazolopyridines, their preparation, pharmaceutical compositions containing them and their use in medicine (pyrazolopyridine derivatives).

Info

Publication number: GC0000112A
Authority: GC; Cooperation Council for the Arab states of the Gulf
Prior art keywords: pyrazolopyridines; medicine; preparation; pharmaceutical compositions; compositions containing
Prior art date: 1998-11-03

Application number

Other languages

English (en)

Inventor

Ian Baxter Campbell

Alan Naylor

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-03

Filing date

1999-11-02

Publication date

2005-06-29

1998-11-03 Priority claimed from GBGB9824062.5A external-priority patent/GB9824062D0/en

1999-09-03 Priority claimed from GBGB9920909.0A external-priority patent/GB9920909D0/en

1999-11-02 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2005-06-29 Application granted granted Critical

2005-06-29 Publication of GC0000112A publication Critical patent/GC0000112A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pulmonology (AREA)
Virology (AREA)
Oncology (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Communicable Diseases (AREA)
Urology & Nephrology (AREA)
AIDS & HIV (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Ophthalmology & Optometry (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
Toxicology (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Psychiatry (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

GCP1999355 1998-11-03 1999-11-02 Pyrazolopyridines, their preparation, pharmaceutical compositions containing them and their use in medicine (pyrazolopyridine derivatives). GC0000112A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9824062.5A GB9824062D0 (en)	1998-11-03	1998-11-03	Chemical compounds
GBGB9920909.0A GB9920909D0 (en)	1999-09-03	1999-09-03	Chemical compounds

Publications (1)

Publication Number	Publication Date
GC0000112A true GC0000112A (en)	2005-06-29

Family

ID=26314603

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GCP1999355 GC0000112A (en)	1998-11-03	1999-11-02	Pyrazolopyridines, their preparation, pharmaceutical compositions containing them and their use in medicine (pyrazolopyridine derivatives).

Country Status (24)

Country	Link
US (1)	US7223772B1 (ja)
EP (1)	EP1127058B1 (ja)
JP (1)	JP3420751B2 (ja)
KR (1)	KR20010075673A (ja)
CN (1)	CN1263755C (ja)
AR (1)	AR021055A1 (ja)
AT (1)	ATE275148T1 (ja)
AU (1)	AU767464B2 (ja)
BR (1)	BR9915011A (ja)
CA (1)	CA2349567A1 (ja)
CO (1)	CO5150164A1 (ja)
CZ (1)	CZ20011556A3 (ja)
DE (1)	DE69919887T2 (ja)
ES (1)	ES2228127T3 (ja)
GC (1)	GC0000112A (ja)
HU (1)	HUP0104204A3 (ja)
MY (1)	MY119689A (ja)
NO (1)	NO318884B1 (ja)
NZ (1)	NZ511349A (ja)
PE (1)	PE20001305A1 (ja)
PL (1)	PL348208A1 (ja)
TR (1)	TR200101208T2 (ja)
TW (1)	TW542836B (ja)
WO (1)	WO2000026216A1 (ja)

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JP2004518651A (ja)	2000-12-15	2004-06-24	グラクソ　グループ　リミテッド	治療用化合物
WO2002048148A2 (en)	2000-12-15	2002-06-20	Glaxo Group Limited	Pyrazolopyridine derivatives
JP2004529119A (ja)	2001-03-08	2004-09-24	スミスクラインビーチャムコーポレーション	ピラゾロピリジン誘導体
JP4237497B2 (ja)	2001-03-30	2009-03-11	スミスクラインビーチャムコーポレーション	ピラゾロピリジン類、その調製方法及びその治療用化合物としての使用
ES2266487T3 (es)	2001-04-10	2007-03-01	Smithkline Beecham Corporation	Compuestos de pirazolopirina antivirales.
US20030105144A1 (en)	2001-04-17	2003-06-05	Ping Gao	Stabilized oral pharmaceutical composition
WO2002088124A2 (en)	2001-04-27	2002-11-07	Smithkline Beecham Corporation	Pyrazolo'1,5-a!pyridine derivatives
ES2271273T3 (es)	2001-06-21	2007-04-16	Smithkline Beecham Corporation	Derivados imidazo-1,2-aipiridina para la profilaxis y tratamiento de las infecciones del virus del herpres.
JP2005507878A (ja) *	2001-09-07	2005-03-24	スミスクラインビーチャムコーポレーション	ヘルペス感染症を治療するためのピラゾロ−ピリジン類
DE60211539T2 (de)	2001-10-05	2006-09-21	Smithkline Beecham Corp.	Imidazopyridinderivate zur verwendung bei der behandlung von herpes-vireninfektion
GB0124936D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
GB0124941D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
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GB0124933D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
GB0124934D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
EP1453830B1 (en)	2001-12-11	2007-09-12	SmithKline Beecham Corporation	Pyrazolo-pyridine derivatives as antiherpes agents
EP1864975B1 (en)	2002-02-12	2010-10-20	GlaxoSmithKline LLC	Nicotinamide derivates useful as P38 inhibitors
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UY27939A1 (es)	2002-08-21	2004-03-31	Glaxo Group Ltd	Compuestos
UA80296C2 (en) *	2002-09-06	2007-09-10	Biogen Inc	Imidazolopyridines and methods of making and using the same
US7153863B2 (en)	2002-10-03	2006-12-26	Smithkline Beecham Corporation	Therapeutic compounds based on pyrazolopyridline derivatives
DE602004029145D1 (de)	2003-02-27	2010-10-28	Palau Pharma Sa	Pyrazolopyridin-derivate
GB0308201D0 (en)	2003-04-09	2003-05-14	Smithkline Beecham Corp	Novel compounds
GB0308186D0 (en)	2003-04-09	2003-05-14	Smithkline Beecham Corp	Novel compounds
GB0308185D0 (en)	2003-04-09	2003-05-14	Smithkline Beecham Corp	Novel compounds
EP1745791B1 (en)	2003-05-07	2013-06-26	Osteologix A/S	Treating cartilage/bone conditions with water-soluble strontium salts
GB0318814D0 (en)	2003-08-11	2003-09-10	Smithkline Beecham Corp	Novel compounds
BRPI0519398A2 (pt)	2004-12-23	2009-01-20	Glaxo Group Ltd	compostos de piridina para o tratamento de doenÇas mediadas por prostaglandina
DE102005024012A1 (de) *	2005-05-20	2006-11-23	Grünenthal GmbH	Verwendung von 2,5-disubstituierten Thiazol-4-on-Derivaten in Arzneimitteln
US7585875B2 (en)	2006-06-06	2009-09-08	Avigen, Inc.	Substituted pyrazolo[1,5-a]pyridine compounds and their methods of use
CN101626787A (zh) *	2007-01-19	2010-01-13	马林克罗特公司	诊断的和治疗的环氧合酶-2结合配体
GB0704407D0 (en)	2007-03-07	2007-04-18	Glaxo Group Ltd	Compounds
US7943658B2 (en)	2007-07-23	2011-05-17	Bristol-Myers Squibb Company	Indole indane amide compounds useful as CB2 agonists and method
UA103319C2 (en)	2008-05-06	2013-10-10	Глаксосмитклайн Ллк	Thiazole- and oxazole-benzene sulfonamide compounds
GB0813144D0 (en)	2008-07-17	2008-08-27	Glaxo Group Ltd	Novel compounds
GB0813142D0 (en)	2008-07-17	2008-08-27	Glaxo Group Ltd	Novel compounds
WO2011012622A1 (en)	2009-07-30	2011-02-03	Glaxo Group Limited	Benzoxazinone derivatives for the treatment of glytl mediated disorders
WO2011023753A1 (en)	2009-08-27	2011-03-03	Glaxo Group Limited	Benzoxazine derivatives as glycine transport inhibitors
GB201000685D0 (en)	2010-01-15	2010-03-03	Glaxo Group Ltd	Novel compounds
GB201007789D0 (en)	2010-05-10	2010-06-23	Glaxo Group Ltd	Novel Compound
GB201007791D0 (en)	2010-05-10	2010-06-23	Glaxo Group Ltd	Novel compounds
WO2012004604A1 (en)	2010-07-09	2012-01-12	Convergence Pharmaceuticals Limited	Tetrazole compounds as calcium channel blockers
ES2541416T3 (es)	2011-01-19	2015-07-20	Convergence Pharmaceuticals Limited	Derivados de piperazina como bloqueadores de los canales de calcio Cav2.2
GB201122113D0 (en)	2011-12-22	2012-02-01	Convergence Pharmaceuticals	Novel compounds
GB201417497D0 (en)	2014-10-03	2014-11-19	Convergence Pharmaceuticals	Novel use
GB201417500D0 (en)	2014-10-03	2014-11-19	Convergence Pharmaceuticals	Novel use
GB201417499D0 (en)	2014-10-03	2014-11-19	Convergence Pharmaceuticals	Novel use
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1999
- 1999-11-01 CZ CZ20011556A patent/CZ20011556A3/cs unknown
- 1999-11-01 AR ARP990105525A patent/AR021055A1/es unknown
- 1999-11-01 WO PCT/EP1999/008186 patent/WO2000026216A1/en not_active Application Discontinuation
- 1999-11-01 BR BR9915011-5A patent/BR9915011A/pt not_active IP Right Cessation
- 1999-11-01 AU AU12667/00A patent/AU767464B2/en not_active Ceased
- 1999-11-01 KR KR1020017005495A patent/KR20010075673A/ko not_active Application Discontinuation
- 1999-11-01 CN CNB99815234XA patent/CN1263755C/zh not_active Expired - Fee Related
- 1999-11-01 TR TR2001/01208T patent/TR200101208T2/xx unknown
- 1999-11-01 NZ NZ511349A patent/NZ511349A/en unknown
- 1999-11-01 ES ES99955897T patent/ES2228127T3/es not_active Expired - Lifetime
- 1999-11-01 DE DE69919887T patent/DE69919887T2/de not_active Expired - Fee Related
- 1999-11-01 AT AT99955897T patent/ATE275148T1/de not_active IP Right Cessation
- 1999-11-01 US US09/830,836 patent/US7223772B1/en not_active Expired - Fee Related
- 1999-11-01 JP JP2000579604A patent/JP3420751B2/ja not_active Expired - Fee Related
- 1999-11-01 EP EP99955897A patent/EP1127058B1/en not_active Expired - Lifetime
- 1999-11-01 HU HU0104204A patent/HUP0104204A3/hu unknown
- 1999-11-01 PL PL99348208A patent/PL348208A1/xx not_active Application Discontinuation
- 1999-11-01 CA CA002349567A patent/CA2349567A1/en not_active Abandoned
- 1999-11-02 MY MYPI99004739A patent/MY119689A/en unknown
- 1999-11-02 GC GCP1999355 patent/GC0000112A/xx active
- 1999-11-02 TW TW088119040A patent/TW542836B/zh not_active IP Right Cessation
- 1999-11-02 CO CO99068974A patent/CO5150164A1/es unknown
- 1999-11-03 PE PE1999001103A patent/PE20001305A1/es not_active Application Discontinuation
2001
- 2001-05-02 NO NO20012156A patent/NO318884B1/no unknown

Also Published As

Publication number	Publication date
DE69919887D1 (de)	2004-10-07
MY119689A (en)	2005-06-30
PE20001305A1 (es)	2000-12-06
JP2002528547A (ja)	2002-09-03
NO318884B1 (no)	2005-05-18
AR021055A1 (es)	2002-06-12
NZ511349A (en)	2003-10-31
NO20012156L (no)	2001-07-02
BR9915011A (pt)	2001-08-07
HUP0104204A2 (hu)	2002-04-29
CN1263755C (zh)	2006-07-12
CA2349567A1 (en)	2000-05-11
AU767464B2 (en)	2003-11-13
EP1127058A1 (en)	2001-08-29
JP3420751B2 (ja)	2003-06-30
CN1332741A (zh)	2002-01-23
CO5150164A1 (es)	2002-04-29
TR200101208T2 (tr)	2001-10-22
US7223772B1 (en)	2007-05-29
PL348208A1 (en)	2002-05-06
TW542836B (en)	2003-07-21
KR20010075673A (ko)	2001-08-09
CZ20011556A3 (cs)	2001-11-14
WO2000026216A1 (en)	2000-05-11
NO20012156D0 (no)	2001-05-02
HUP0104204A3 (en)	2002-06-28
AU1266700A (en)	2000-05-22
ES2228127T3 (es)	2005-04-01
EP1127058B1 (en)	2004-09-01
DE69919887T2 (de)	2005-09-15
ATE275148T1 (de)	2004-09-15

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