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FR2756285B1 - Derives de n-(imidazolylbutyle)benzenesulfonamide, leur preparation et leur application en therapeutique - Google Patents

Derives de n-(imidazolylbutyle)benzenesulfonamide, leur preparation et leur application en therapeutique

Info

Publication number
FR2756285B1
FR2756285B1 FR9614309A FR9614309A FR2756285B1 FR 2756285 B1 FR2756285 B1 FR 2756285B1 FR 9614309 A FR9614309 A FR 9614309A FR 9614309 A FR9614309 A FR 9614309A FR 2756285 B1 FR2756285 B1 FR 2756285B1
Authority
FR
France
Prior art keywords
imidazolylbutyl
preparation
therapeutic application
benzenesulfonamide derivatives
benzenesulfonamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9614309A
Other languages
English (en)
Other versions
FR2756285A1 (fr
Inventor
Jean Michel Altenburger
Gilbert Lassalle
Valerie Martin
Daniel Galtier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9614309A priority Critical patent/FR2756285B1/fr
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to CA002270478A priority patent/CA2270478A1/fr
Priority to CN97199986A priority patent/CN1238765A/zh
Priority to IL12954697A priority patent/IL129546A0/xx
Priority to CZ991782A priority patent/CZ178299A3/cs
Priority to KR1019997004485A priority patent/KR20000069063A/ko
Priority to EP97947089A priority patent/EP0946517A1/fr
Priority to TR1999/01143T priority patent/TR199901143T2/xx
Priority to PCT/FR1997/002079 priority patent/WO1998022443A1/fr
Priority to EEP199900201A priority patent/EE9900201A/xx
Priority to AU52264/98A priority patent/AU5226498A/en
Priority to JP52328498A priority patent/JP2001504128A/ja
Priority to HU9904599A priority patent/HUP9904599A2/hu
Priority to BR9713291-8A priority patent/BR9713291A/pt
Priority to CO97067574A priority patent/CO4910158A1/es
Priority to SK667-99A priority patent/SK66799A3/sk
Priority to ZA9710515A priority patent/ZA9710515B/xx
Priority to ARP970105455A priority patent/AR009627A1/es
Publication of FR2756285A1 publication Critical patent/FR2756285A1/fr
Publication of FR2756285B1 publication Critical patent/FR2756285B1/fr
Application granted granted Critical
Priority to BG103414A priority patent/BG103414A/xx
Priority to NO992436A priority patent/NO992436L/no
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR9614309A 1996-11-22 1996-11-22 Derives de n-(imidazolylbutyle)benzenesulfonamide, leur preparation et leur application en therapeutique Expired - Fee Related FR2756285B1 (fr)

Priority Applications (20)

Application Number Priority Date Filing Date Title
FR9614309A FR2756285B1 (fr) 1996-11-22 1996-11-22 Derives de n-(imidazolylbutyle)benzenesulfonamide, leur preparation et leur application en therapeutique
HU9904599A HUP9904599A2 (hu) 1996-11-22 1997-11-19 N-(Imidazolil-butil)-benzolszulfanomid-származékok, eljárás előállításukra és alkalmazásuk a gyógyászatban
IL12954697A IL129546A0 (en) 1996-11-22 1997-11-19 N-(imidazolylbutyl)benzenesulphonamide derivatives their preparation and their application in therapeutics
CZ991782A CZ178299A3 (cs) 1996-11-22 1997-11-19 Deriváty N-(imidazolylbutyl)benzensulfonamidu, způsob jejich přípravy a jejich použití pro léčebné účely
KR1019997004485A KR20000069063A (ko) 1996-11-22 1997-11-19 Ｎ-(이미다졸릴부틸)벤젠설폰아미드 유도체, 이들의 제법 및치료에의 응용
EP97947089A EP0946517A1 (fr) 1996-11-22 1997-11-19 Derives de n-(imidazolylbutyle) benzenesulfonamide ayant une activite antithrombotique
TR1999/01143T TR199901143T2 (xx) 1996-11-22 1997-11-19 N-(�midazolilb�til ) benzens�lfonamid t�revleri, haz�rlanmalar� ve terapide uygulanmalar�.
CN97199986A CN1238765A (zh) 1996-11-22 1997-11-19 具有抗凝血活性的n－(咪唑基丁基)苯磺酰胺衍生物
EEP199900201A EE9900201A (et) 1996-11-22 1997-11-19 N-(imidasolüülbutüül)benseensulfoonamiidi derivaadid, nende valmistamine ja kasutamine terapeutikas
AU52264/98A AU5226498A (en) 1996-11-22 1997-11-19 N-(imidazolylbutyl) benzenesulphonamide derivatives, their preparation and the rapeutic application
CA002270478A CA2270478A1 (fr) 1996-11-22 1997-11-19 Derives de n-(imidazolylbutyle) benzenesulfonamide ayant une activite antithrombotique
JP52328498A JP2001504128A (ja) 1996-11-22 1997-11-19 Ｎ―（イミダゾリルブチル）ベンゼンスルホンアミド誘導体、その製造法およびその治療上の応用
SK667-99A SK66799A3 (en) 1996-11-22 1997-11-19 N-(imidazolylbutyl) benzenesulphonamide derivatives, their preparation and therapeutic application
CO97067574A CO4910158A1 (es) 1996-11-22 1997-11-19 Derivados de n-(imidazolilbutilo) bencenosulfonamida, su preparacion y su aplicacion en terapeutica
BR9713291-8A BR9713291A (pt) 1996-11-22 1997-11-19 Derivados de n-(imidazolilbutila) benzeno-sulfonamida que tem uma atividade antitrobótica
PCT/FR1997/002079 WO1998022443A1 (fr) 1996-11-22 1997-11-19 Derives de n-(imidazolylbutyle) benzenesulfonamide ayant une activite antithrombotique
ZA9710515A ZA9710515B (en) 1996-11-22 1997-11-21 N-(imidazolybutyl) benezenesulphonamide derivatives, their preparation and their application in therapeutics.
ARP970105455A AR009627A1 (es) 1996-11-22 1997-11-21 Derivados de n-(imidazolilbutil)bencenosulfonamida su preparacion y su aplicacion en terapeutica
BG103414A BG103414A (en) 1996-11-22 1999-05-19 N-(imidazolylbutyl)benzenesulphonamide derivatives, method for their prepraration and application as medicaments
NO992436A NO992436L (no) 1996-11-22 1999-05-20 N(imidazolylbutyl)benzensulfonamidderivater, deres fremstilling og terapeutiske anvendelse

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9614309A FR2756285B1 (fr) 1996-11-22 1996-11-22 Derives de n-(imidazolylbutyle)benzenesulfonamide, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2756285A1 FR2756285A1 (fr) 1998-05-29
FR2756285B1 true FR2756285B1 (fr) 1998-12-18

Family

ID=9497920

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9614309A Expired - Fee Related FR2756285B1 (fr) 1996-11-22 1996-11-22 Derives de n-(imidazolylbutyle)benzenesulfonamide, leur preparation et leur application en therapeutique

Country Status (20)

Country Link
EP (1) EP0946517A1 (fr)
JP (1) JP2001504128A (fr)
KR (1) KR20000069063A (fr)
CN (1) CN1238765A (fr)
AR (1) AR009627A1 (fr)
AU (1) AU5226498A (fr)
BG (1) BG103414A (fr)
BR (1) BR9713291A (fr)
CA (1) CA2270478A1 (fr)
CO (1) CO4910158A1 (fr)
CZ (1) CZ178299A3 (fr)
EE (1) EE9900201A (fr)
FR (1) FR2756285B1 (fr)
HU (1) HUP9904599A2 (fr)
IL (1) IL129546A0 (fr)
NO (1) NO992436L (fr)
SK (1) SK66799A3 (fr)
TR (1) TR199901143T2 (fr)
WO (1) WO1998022443A1 (fr)
ZA (1) ZA9710515B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2783521B1 (fr) * 1998-09-18 2002-04-26 Synthelabo Derives de n-(arginyl) benzenesulfonamide, leur preparation et leur application en therapeutique
FR2806722B1 (fr) * 2000-03-23 2002-05-17 Sanofi Synthelabo Derives de n-(heterocyclylbutyl) benzene-ou pyridine sulfonamide, leur preparation et leur application en therapeutique
ES2799309T3 (es) 2014-09-29 2020-12-16 Cellix Bio Private Ltd Compuestos y composiciones para el tratamiento de esclerosis múltiple

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2689130B1 (fr) * 1992-03-30 1994-05-27 Synthelabo Derives de 1-[2 (arylsulfonylamino)ethyl-1-oxo] piperidine, leur preparation et leur application en therapeutique.
FR2710066B1 (fr) * 1993-09-14 1995-10-20 Synthelabo Dérivés de 1-[2-amino-5-[1-(triphénylméthyl-1H-imidazol-4-yl]-1-oxopentyl]piperidine, leur préparation et leur utilisation comme intermédiaires de synthèse.
FR2727410B1 (fr) * 1994-11-25 1996-12-20 Synthelabo Chlorures de sulfonyles, leur preparation et leur utilisation comme intermediaires de synthese
FR2728570B1 (fr) * 1994-12-23 1997-04-11 Synthelabo Derives de 1-oxo-2-(phenylsulfonylamino)pentylpiperidine, leur preparation et leur application en therapeutique
DE19548797A1 (de) * 1995-12-27 1997-07-03 Thomae Gmbh Dr K Substituierte 2-Amino-imidazole, ihre Herstellung und ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
NO992436L (no) 1999-07-22
WO1998022443A1 (fr) 1998-05-28
NO992436D0 (no) 1999-05-20
IL129546A0 (en) 2000-02-29
EP0946517A1 (fr) 1999-10-06
BR9713291A (pt) 1999-10-26
AU5226498A (en) 1998-06-10
KR20000069063A (ko) 2000-11-25
CN1238765A (zh) 1999-12-15
CZ178299A3 (cs) 1999-08-11
ZA9710515B (en) 1998-06-10
JP2001504128A (ja) 2001-03-27
BG103414A (en) 2000-01-31
TR199901143T2 (xx) 1999-08-23
EE9900201A (et) 1999-12-15
SK66799A3 (en) 2000-02-14
HUP9904599A2 (hu) 2000-06-28
AR009627A1 (es) 2000-04-26
CO4910158A1 (es) 2000-04-24
CA2270478A1 (fr) 1998-05-28
FR2756285A1 (fr) 1998-05-29

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Legal Events

Date Code Title Description
ST Notification of lapse