FR2769915B1 - Derives d'indazole tricycliques, leur preparation et leur application en therapeutique - Google Patents
Derives d'indazole tricycliques, leur preparation et leur application en therapeutiqueInfo
- Publication number
- FR2769915B1 FR2769915B1 FR9713149A FR9713149A FR2769915B1 FR 2769915 B1 FR2769915 B1 FR 2769915B1 FR 9713149 A FR9713149 A FR 9713149A FR 9713149 A FR9713149 A FR 9713149A FR 2769915 B1 FR2769915 B1 FR 2769915B1
- Authority
- FR
- France
- Prior art keywords
- preparation
- therapeutic application
- indazole derivatives
- tricyclic indazole
- tricyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9713149A FR2769915B1 (fr) | 1997-10-21 | 1997-10-21 | Derives d'indazole tricycliques, leur preparation et leur application en therapeutique |
PCT/FR1998/002221 WO1999020633A1 (fr) | 1997-10-21 | 1998-10-16 | Derives de benzoxazine, leur preparation et leur application en therapeutique |
EP98950149A EP1025109A1 (fr) | 1997-10-21 | 1998-10-16 | Derives de benzoxazine, leur preparation et leur application en therapeutique |
AU96330/98A AU9633098A (en) | 1997-10-21 | 1998-10-16 | Benzoxazine derivatives, preparation and application in therapy |
JP2000516974A JP2001520231A (ja) | 1997-10-21 | 1998-10-16 | ベンゾオキサジン誘導体、その製造およびその治療における適用 |
ARP980105207A AR017366A1 (es) | 1997-10-21 | 1998-10-20 | Un compuesto derivado de 7,8-dihidropirazol[1,5,4-de][1,4]benzoxazina, procedimiento para prepararlo, medicamento, constituido por dicho compuestoy composicion farmaceutica que contiene a dicho compuesto. |
ZA989556A ZA989556B (en) | 1997-10-21 | 1998-10-20 | Benzoxazine derivatives their preparation and their therapeutic application |
TW087117333A TW407160B (en) | 1997-10-21 | 1998-10-20 | Tricyclic indazole derivative compounds, processes for the preparation thereof and pharmaceutical compositions comprising the compounds |
CO98060914A CO4990933A1 (es) | 1997-10-21 | 1998-10-20 | Derivados de indazol triciclicos, su preparacion y su apli- cacion en terapeutica |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9713149A FR2769915B1 (fr) | 1997-10-21 | 1997-10-21 | Derives d'indazole tricycliques, leur preparation et leur application en therapeutique |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2769915A1 FR2769915A1 (fr) | 1999-04-23 |
FR2769915B1 true FR2769915B1 (fr) | 2000-10-13 |
Family
ID=9512452
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9713149A Expired - Fee Related FR2769915B1 (fr) | 1997-10-21 | 1997-10-21 | Derives d'indazole tricycliques, leur preparation et leur application en therapeutique |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1025109A1 (fr) |
JP (1) | JP2001520231A (fr) |
AR (1) | AR017366A1 (fr) |
AU (1) | AU9633098A (fr) |
CO (1) | CO4990933A1 (fr) |
FR (1) | FR2769915B1 (fr) |
TW (1) | TW407160B (fr) |
WO (1) | WO1999020633A1 (fr) |
ZA (1) | ZA989556B (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7718608B2 (en) | 1999-08-11 | 2010-05-18 | Cedars-Sinai Medical Center | Methods of treating a subject suffering from irritable bowel syndrome |
US8388935B2 (en) | 1999-08-11 | 2013-03-05 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6558708B1 (en) * | 1995-05-17 | 2003-05-06 | Cedars-Sinai Medical Center | Methods for manipulating upper gastrointestinal transit, blood flow, and satiety, and for treating visceral hyperalgesia |
FR2792318B1 (fr) * | 1999-04-16 | 2001-06-15 | Synthelabo | Derives d'indazole, leur preparation et leur application en therapeutique |
AR036040A1 (es) | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen |
EA007429B1 (ru) | 2001-10-02 | 2006-10-27 | Фармация Энд Апджон Компани | Азабициклические замещённые конденсированные гетероарильные соединения |
EP1442037A1 (fr) | 2001-11-09 | 2004-08-04 | PHARMACIA & UPJOHN COMPANY | Composes heterocycliques fusionnes avec un groupe phenyl-azabicyclique et leur utilisation en tant que ligands de recepteur nachr alpha 7 |
US6858613B2 (en) | 2002-02-19 | 2005-02-22 | Pfizer Inc. | Fused bicyclic-N-bridged-heteroaromatic carboxamides for the treatment of disease |
JP2005523287A (ja) | 2002-02-19 | 2005-08-04 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 疾患治療用アザビシクロ化合物 |
TW200533348A (en) | 2004-02-18 | 2005-10-16 | Theravance Inc | Indazole-carboxamide compounds as 5-ht4 receptor agonists |
TWI351282B (en) | 2004-04-07 | 2011-11-01 | Theravance Inc | Quinolinone-carboxamide compounds as 5-ht4 recepto |
US8309575B2 (en) | 2004-04-07 | 2012-11-13 | Theravance, Inc. | Quinolinone-carboxamide compounds as 5-HT4 receptor agonists |
US7728006B2 (en) | 2004-04-07 | 2010-06-01 | Theravance, Inc. | Quinolinone-carboxamide compounds as 5-HT4 receptor agonists |
JP5042028B2 (ja) | 2004-11-05 | 2012-10-03 | セラヴァンス, インコーポレーテッド | キノリノン−カルボキサミド化合物 |
WO2006052640A1 (fr) | 2004-11-05 | 2006-05-18 | Theravance, Inc. | Composés antagonistes du récepteur 5-ht4 |
EP1831211B1 (fr) | 2004-12-22 | 2010-06-02 | Theravance, Inc. | Composes d'indazole-carboxamide |
PL1828179T3 (pl) * | 2004-12-22 | 2010-08-31 | Memory Pharm Corp | Ligandy dla receptorów nikotynowych alfa-7 przeciwko chorobom związanym z OUN |
EA013567B1 (ru) | 2005-03-02 | 2010-06-30 | Тереванс, Инк. | Хинолиноновые соединения в качестве агонистов рецептора 5-ht |
JP4375749B2 (ja) | 2005-11-22 | 2009-12-02 | 本田技研工業株式会社 | 車両の樹脂製ガーニッシュ構造 |
WO2007120599A2 (fr) | 2006-04-12 | 2007-10-25 | Wyeth | Dérivés de dihydro[1,4]oxazino[2,3,4-hi]indazole en tant que ligands de 5-hydroxytryptamine-6 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0350130A3 (fr) * | 1988-07-07 | 1991-07-10 | Duphar International Research B.V | 1H-indazoles 1,7-annelés substitués |
FR2753196B1 (fr) * | 1996-09-12 | 1998-10-23 | Synthelabo | Derives d'indazole tricyclique, leur preparation et leur application en therapeutique |
-
1997
- 1997-10-21 FR FR9713149A patent/FR2769915B1/fr not_active Expired - Fee Related
-
1998
- 1998-10-16 EP EP98950149A patent/EP1025109A1/fr not_active Withdrawn
- 1998-10-16 WO PCT/FR1998/002221 patent/WO1999020633A1/fr not_active Application Discontinuation
- 1998-10-16 JP JP2000516974A patent/JP2001520231A/ja not_active Withdrawn
- 1998-10-16 AU AU96330/98A patent/AU9633098A/en not_active Abandoned
- 1998-10-20 CO CO98060914A patent/CO4990933A1/es unknown
- 1998-10-20 TW TW087117333A patent/TW407160B/zh not_active IP Right Cessation
- 1998-10-20 ZA ZA989556A patent/ZA989556B/xx unknown
- 1998-10-20 AR ARP980105207A patent/AR017366A1/es unknown
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7718608B2 (en) | 1999-08-11 | 2010-05-18 | Cedars-Sinai Medical Center | Methods of treating a subject suffering from irritable bowel syndrome |
US7935799B2 (en) | 1999-08-11 | 2011-05-03 | Cedars-Sinai Medical Center | Methods of treating diarrhea caused by small intestinal bacterial overgrowth |
US8197805B2 (en) | 1999-08-11 | 2012-06-12 | Cedars-Sinai Medical Center | Methods of treating autoimmune diseases caused by small intestinal bacterial overgrowth |
US8388935B2 (en) | 1999-08-11 | 2013-03-05 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
US8562952B2 (en) | 1999-08-11 | 2013-10-22 | Cedars-Sinai Medical Center | Methods for manipulating satiety |
US9358276B2 (en) | 1999-08-11 | 2016-06-07 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
Also Published As
Publication number | Publication date |
---|---|
ZA989556B (en) | 1999-04-20 |
FR2769915A1 (fr) | 1999-04-23 |
CO4990933A1 (es) | 2000-12-26 |
JP2001520231A (ja) | 2001-10-30 |
EP1025109A1 (fr) | 2000-08-09 |
WO1999020633A1 (fr) | 1999-04-29 |
TW407160B (en) | 2000-10-01 |
AR017366A1 (es) | 2001-09-05 |
AU9633098A (en) | 1999-05-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TP | Transmission of property | ||
ST | Notification of lapse |