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FR2746412B1 - Purification d'adn plasmidique de qualite pharmaceutique - Google Patents

Purification d'adn plasmidique de qualite pharmaceutique

Info

Publication number
FR2746412B1
FR2746412B1 FR9603519A FR9603519A FR2746412B1 FR 2746412 B1 FR2746412 B1 FR 2746412B1 FR 9603519 A FR9603519 A FR 9603519A FR 9603519 A FR9603519 A FR 9603519A FR 2746412 B1 FR2746412 B1 FR 2746412B1
Authority
FR
France
Prior art keywords
purification
plasmid dna
pharmaceutical quality
pharmaceutical
quality
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9603519A
Other languages
English (en)
Other versions
FR2746412A1 (fr
Inventor
Monique Ollivier
Pierre Wils
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9603519A priority Critical patent/FR2746412B1/fr
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Priority to AU21661/97A priority patent/AU730755B2/en
Priority to BR9708227A priority patent/BR9708227A/pt
Priority to KR10-1998-0707410A priority patent/KR100502116B1/ko
Priority to SK1291-98A priority patent/SK129198A3/sk
Priority to JP9533199A priority patent/JP2000506736A/ja
Priority to CA002249465A priority patent/CA2249465A1/fr
Priority to IL12626897A priority patent/IL126268A0/xx
Priority to PCT/FR1997/000472 priority patent/WO1997035002A1/fr
Priority to EP97914411A priority patent/EP0902835A1/fr
Priority to CZ19982984A priority patent/CZ295587B6/cs
Priority to HU9902152A priority patent/HU225426B1/hu
Priority to ZA9702462A priority patent/ZA972462B/xx
Publication of FR2746412A1 publication Critical patent/FR2746412A1/fr
Application granted granted Critical
Publication of FR2746412B1 publication Critical patent/FR2746412B1/fr
Priority to US09/153,838 priority patent/US6730781B1/en
Priority to NO984342A priority patent/NO984342D0/no
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/101—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by chromatography, e.g. electrophoresis, ion-exchange, reverse phase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9603519A 1996-03-21 1996-03-21 Purification d'adn plasmidique de qualite pharmaceutique Expired - Fee Related FR2746412B1 (fr)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR9603519A FR2746412B1 (fr) 1996-03-21 1996-03-21 Purification d'adn plasmidique de qualite pharmaceutique
CZ19982984A CZ295587B6 (cs) 1996-03-21 1997-03-17 Purifikace plazmidové DNA farmaceutické kvality
KR10-1998-0707410A KR100502116B1 (ko) 1996-03-21 1997-03-17 약제성 플라스미드 디엔에이의 정제
SK1291-98A SK129198A3 (en) 1996-03-21 1997-03-17 Purification of pharmaceutical-grade plasmid dna
JP9533199A JP2000506736A (ja) 1996-03-21 1997-03-17 医薬品質のプラスミドｄｎａの精製
CA002249465A CA2249465A1 (fr) 1996-03-21 1997-03-17 Purification d'adn plasmidique de qualite pharmaceutique
IL12626897A IL126268A0 (en) 1996-03-21 1997-03-17 Purification of plasmid dna of pharmaceutical quality
PCT/FR1997/000472 WO1997035002A1 (fr) 1996-03-21 1997-03-17 Purification d'adn plasmidique de qualite pharmaceutique
AU21661/97A AU730755B2 (en) 1996-03-21 1997-03-17 Purification of plasmid DNA of pharmaceutical quality
BR9708227A BR9708227A (pt) 1996-03-21 1997-03-17 Processo de purificação de dna duplo filamento de pureza farmacêutica preparação de dna plasmídico recombinante e composição farmacêutica
HU9902152A HU225426B1 (en) 1996-03-21 1997-03-17 Method for purification of double stranded plasmid dna
EP97914411A EP0902835A1 (fr) 1996-03-21 1997-03-17 Purification d'adn plasmidique de qualite pharmaceutique
ZA9702462A ZA972462B (en) 1996-03-21 1997-03-20 Purification of plasmid DNA of pharmaceutical quality.
US09/153,838 US6730781B1 (en) 1996-03-21 1998-09-15 Purification of plasmid DNA of pharmaceutical quality
NO984342A NO984342D0 (no) 1996-03-21 1998-09-18 Rensing av plasmid-DNA av farmas°ytisk kvalitet

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9603519A FR2746412B1 (fr) 1996-03-21 1996-03-21 Purification d'adn plasmidique de qualite pharmaceutique

Publications (2)

Publication Number Publication Date
FR2746412A1 FR2746412A1 (fr) 1997-09-26
FR2746412B1 true FR2746412B1 (fr) 1998-06-12

Family

ID=9490391

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9603519A Expired - Fee Related FR2746412B1 (fr) 1996-03-21 1996-03-21 Purification d'adn plasmidique de qualite pharmaceutique

Country Status (15)

Country Link
US (1) US6730781B1 (fr)
EP (1) EP0902835A1 (fr)
JP (1) JP2000506736A (fr)
KR (1) KR100502116B1 (fr)
AU (1) AU730755B2 (fr)
BR (1) BR9708227A (fr)
CA (1) CA2249465A1 (fr)
CZ (1) CZ295587B6 (fr)
FR (1) FR2746412B1 (fr)
HU (1) HU225426B1 (fr)
IL (1) IL126268A0 (fr)
NO (1) NO984342D0 (fr)
SK (1) SK129198A3 (fr)
WO (1) WO1997035002A1 (fr)
ZA (1) ZA972462B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7026468B2 (en) 1996-07-19 2006-04-11 Valentis, Inc. Process and equipment for plasmid purification
US7807822B2 (en) 1996-08-01 2010-10-05 Robert Bridenbaugh Methods for purifying nucleic acids
US6214586B1 (en) * 1997-12-08 2001-04-10 Genzyme Corporation Method for purifying plasmid DNA and plasmid DNA substantially free of genomic DNA
AU2001263459B2 (en) * 2000-05-26 2007-03-15 Centelion S.A.S. Purification of a triple heli formation with an immobilized oligonucleotide
FR2822476B1 (fr) * 2001-03-23 2004-04-02 Aventis Pharma Sa Procedes de purification et de detection de sequences cibles d'adn double brin par interaction triple helice
NZ528507A (en) * 2001-03-23 2005-08-26 Centelion S Processes for purifying and for detecting target double-stranded DNA sequences by triple helix interaction
US7314746B2 (en) 2002-09-13 2008-01-01 Valentis, Inc. Apparatus and method for preparative scale purification of nucleic acids
DK1628749T3 (da) 2003-05-30 2019-09-16 Vgxi Inc Anordninger og fremgangsmåder til biomateriel produktion
NZ545449A (en) * 2003-09-17 2009-07-31 Centelion Formerly Gencell Sas Device and Method of preparation of pharmaceutical grade plasmid DNA
CN102031258A (zh) * 2004-04-19 2011-04-27 艾文蒂斯药品公司 纯化质粒dna的方法
SI1737945T1 (sl) * 2004-04-19 2011-05-31 Aventis Pharma Sa Postopek za čiščenje plazmidne DNA
BRPI0515418A (pt) 2004-08-16 2008-07-22 Nature Technology Corp método para a produção de dna de plasmìdio super-enrolado fechado covalentemente e composição de matéria
WO2006060282A2 (fr) 2004-11-30 2006-06-08 Merial Limited Melangeurs pour chimiolyse de cellules
US20120258502A1 (en) * 2011-04-08 2012-10-11 Vinod Pandiripally Method of producing recombinant plasmid dna using substantially solid growth medium
US20120283503A1 (en) * 2011-04-29 2012-11-08 The Johns Hopkins University Nanoparticle loaded stem cells and their use in mri guided hyperthermia
CN116790578B (zh) * 2023-08-22 2023-12-12 赛奥斯博生物科技(北京)有限公司 一种基于碱裂解法快速纯化质粒的生产工艺

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3888079T2 (de) * 1987-10-22 1994-07-14 Asahi Optical Co Ltd Poröses keramisches Material.
JPH01135792A (ja) * 1987-11-20 1989-05-29 Mitsui Toatsu Chem Inc 核酸の分離・精製方法
CA2006008C (fr) * 1988-12-20 2000-02-15 Donald J. Kessler Methode pour obtenir des oligonucleotides synthetiques qui se lient specifiquement a des sites cibles sur des molecules d'adn double brin, en formant un triplex colineaire; methode d'utilisation de ces oligonucleotides synthetiques
JPH08505534A (ja) * 1993-01-13 1996-06-18 森永乳業株式会社 Ｍ−ｃｓｆ２２３の製造方法
US5503816A (en) * 1993-09-27 1996-04-02 Becton Dickinson And Company Silicate compounds for DNA purification
WO1995021179A1 (fr) * 1994-02-07 1995-08-10 Qiagen Gmbh Procede de reduction ou d'elimination d'endotoxines
US5576196A (en) * 1995-01-13 1996-11-19 Vical Incorporated Process for reducing RNA concentration in a mixture of biological material using diatomaceous earth
CN1121408C (zh) 1996-02-06 2003-09-17 罗赫诊断器材股份有限公司 质粒dna制剂、其制备方法、药物组合物、及其应用

Also Published As

Publication number Publication date
AU2166197A (en) 1997-10-10
ZA972462B (en) 1997-09-29
CZ298498A3 (cs) 1999-01-13
AU730755B2 (en) 2001-03-15
FR2746412A1 (fr) 1997-09-26
HUP9902152A3 (en) 2001-04-28
KR20000064693A (ko) 2000-11-06
BR9708227A (pt) 1999-07-27
KR100502116B1 (ko) 2005-12-20
SK129198A3 (en) 1999-03-12
NO984342L (no) 1998-09-18
IL126268A0 (en) 1999-05-09
EP0902835A1 (fr) 1999-03-24
WO1997035002A1 (fr) 1997-09-25
NO984342D0 (no) 1998-09-18
CA2249465A1 (fr) 1997-09-25
CZ295587B6 (cs) 2005-08-17
HUP9902152A2 (hu) 1999-11-29
HU225426B1 (en) 2006-11-28
US6730781B1 (en) 2004-05-04
JP2000506736A (ja) 2000-06-06

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Legal Events

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CD Change of name or company name
ST Notification of lapse

Effective date: 20091130