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FR2400904A1 - Preparations pour administration vaginale et leur utilisation comme agents provoquant l'ovulation ou comme agents anti-mitotiques - Google Patents

Preparations pour administration vaginale et leur utilisation comme agents provoquant l'ovulation ou comme agents anti-mitotiques

Info

Publication number
FR2400904A1
FR2400904A1 FR7824516A FR7824516A FR2400904A1 FR 2400904 A1 FR2400904 A1 FR 2400904A1 FR 7824516 A FR7824516 A FR 7824516A FR 7824516 A FR7824516 A FR 7824516A FR 2400904 A1 FR2400904 A1 FR 2400904A1
Authority
FR
France
Prior art keywords
agents
vaginal administration
preparations
mitotic
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7824516A
Other languages
English (en)
Other versions
FR2400904B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP52101945A external-priority patent/JPS6047249B2/ja
Priority claimed from JP3933778A external-priority patent/JPS54132221A/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FR2400904A1 publication Critical patent/FR2400904A1/fr
Application granted granted Critical
Publication of FR2400904B1 publication Critical patent/FR2400904B1/fr
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/13Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Préparation pour administration vaginale Cette préparation contient, comme ingrédient pharmaceutiquement actif principal un peptide ayant une activité d'hormone libérant l'hormone luteinisante et dont l'absorption est améliorée en ajoutant un acide carboxylique aliphatique aquasoluble ayant 2 à 6 atomes de carbone. Utilisation de cette préparation, comme médicament oestrogène ou anti-mitotique.
FR7824516A 1977-08-24 1978-08-23 Preparations pour administration vaginale et leur utilisation comme agents provoquant l'ovulation ou comme agents anti-mitotiques Granted FR2400904A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP52101945A JPS6047249B2 (ja) 1977-08-24 1977-08-24 膣投与剤
JP3933778A JPS54132221A (en) 1978-04-03 1978-04-03 Water-based medicine for vaginal administration

Publications (2)

Publication Number Publication Date
FR2400904A1 true FR2400904A1 (fr) 1979-03-23
FR2400904B1 FR2400904B1 (fr) 1982-07-30

Family

ID=26378690

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7824516A Granted FR2400904A1 (fr) 1977-08-24 1978-08-23 Preparations pour administration vaginale et leur utilisation comme agents provoquant l'ovulation ou comme agents anti-mitotiques

Country Status (8)

Country Link
US (1) US4211769A (fr)
AU (1) AU517349B2 (fr)
CA (1) CA1112570A (fr)
CH (1) CH634992A5 (fr)
DE (1) DE2836631A1 (fr)
FR (1) FR2400904A1 (fr)
GB (1) GB2003386B (fr)
IT (1) IT1098199B (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2465486A1 (fr) * 1979-09-21 1981-03-27 Roussel Uclaf Nouvelle application utilisant la lh-rh ou des agonistes
EP0052510A2 (fr) * 1980-11-18 1982-05-26 Syntex (U.S.A.) Inc. Microencapsulation de polypeptides hydrosolubles
EP0067513A2 (fr) * 1981-05-14 1982-12-22 Takeda Chemical Industries, Ltd. Préparations pharmaceutiques contenant du TRH ou son analogue
EP0130409A2 (fr) * 1983-06-07 1985-01-09 Takeda Chemical Industries, Ltd. Corps composite à libération lente et procédé de sa préparation

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5389613A (en) * 1979-09-21 1995-02-14 Roussel Uclaf Method of treating prostate adenocarcinoma, prostate benign hypertrophia and endometriosis
EP0041286B1 (fr) * 1980-06-02 1984-08-15 Andrew Victor Schally Antagonistes de la LH-RH
US4675189A (en) * 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
JPS59139315A (ja) * 1983-01-31 1984-08-10 Taisho Pharmaceut Co Ltd クリ−ム剤
GB8308330D0 (en) * 1983-03-25 1983-05-05 Crighton D B Immunogenic compositions
US4801475A (en) * 1984-08-23 1989-01-31 Gregory Halpern Method of hydrophilic coating of plastics
HU193607B (en) * 1985-07-18 1987-11-30 Innofinance Altalanos Innovaci Process for production of sexual products applyable for natural or artificial insemination for mammates
US4663233A (en) * 1985-10-24 1987-05-05 Universal High Technologies Lens with hydrophilic coating
US4746504A (en) * 1986-03-14 1988-05-24 Bio-Technology General Corp. Heavy metal salts of hyaluronic acid and their use as antimicrobial agents
EP0259485A4 (fr) * 1986-03-14 1988-07-29 Bio Technology General Corp Sels de metaux lourds de l'acide hyaluronique utiles en tant qu'agents antimicrobiens.
US4784991A (en) * 1986-03-14 1988-11-15 Bio-Technology General Corp. Heavy metal salts of hyaluronic acid and their use as antimicrobial agents
JPH01501937A (ja) * 1986-11-18 1989-07-06 セネテック・ピーエルシー 腟潤滑誘発方法
US4897268A (en) * 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
DE3928677C2 (de) * 1989-08-30 1998-05-14 Kimberly Clark Gmbh Tampon für medizinische oder hygienische Zwecke sowie Verfahren zu seiner Herstellung
JP2997488B2 (ja) * 1989-12-25 2000-01-11 興研株式会社 腫瘍細胞増殖抑制剤
AU653026B2 (en) * 1991-06-07 1994-09-15 Teikoku Seiyaku Kabushiki Kaisha Physiologically active polypeptide-containing pharmaceutical composition
EP0527241B1 (fr) * 1991-07-15 1994-03-16 Artesan Pharma Gesellschaft mit beschränkter Haftung L'utilisation d'acide ascorbique pour la préparation d'un médicament pour utilisation dans la région génitale
US5518730A (en) 1992-06-03 1996-05-21 Fuisz Technologies Ltd. Biodegradable controlled release flash flow melt-spun delivery system
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
CA2145418A1 (fr) 1992-09-29 1994-04-14 John S. Patton Administration pulmonaire de fragments actifs de l'hormone parathyroidienne
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
US7448375B2 (en) 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
EP2036541A1 (fr) * 1994-03-07 2009-03-18 Nektar Therapeutics Procédés et compositions pour l'administration pulmonaire d'insuline
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US6428771B1 (en) * 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
HUP0100221A3 (en) * 1998-01-16 2002-11-28 Takeda Pharmaceutical Sustained release compositions, process for producing the same and utilization thereof
WO2001000654A2 (fr) * 1999-06-29 2001-01-04 Pharmaceutical Discovery Corporation Purification et stabilisation de produits pharmaceutiques a base de peptides et de proteines
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
MXPA02001323A (es) 2000-05-10 2004-07-16 Alliance Pharma Microgranulos con base fosfolipida para la liberacion de farmaco.
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
AU2002241723A1 (en) * 2000-12-21 2002-07-24 Inhale Therapeutic Systems, Inc. Storage stable powder compositions of interleukin-4 receptor
WO2003053411A1 (fr) 2001-12-19 2003-07-03 Nektar Therapeutics Administration pulmonaire d'aminoglycosides
CA2479751C (fr) 2002-03-20 2008-06-03 Trent Poole Appareil d'inhalation
ATE409220T1 (de) * 2002-03-21 2008-10-15 Bifodan As Lactobacillus-stämme
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
KR101139112B1 (ko) * 2002-06-25 2012-04-30 다케다 야쿠힌 고교 가부시키가이샤 서방성 조성물의 제조 방법
AU2003266142A1 (en) * 2002-09-12 2004-04-30 Biosyn, Inc. Mucus formulation for mucosal surfaces and uses thereof
US7338171B2 (en) * 2003-10-27 2008-03-04 Jen-Chuen Hsieh Method and apparatus for visual drive control
CN101027082A (zh) * 2004-01-12 2007-08-29 曼恩坎德公司 降低2型糖尿病患者血清胰岛素原水平的方法
WO2005072803A1 (fr) * 2004-01-16 2005-08-11 Biodel, Inc. Dispositif d'administration sublinguale de medicaments
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
EP2106790B1 (fr) * 2004-03-12 2012-10-24 Biodel, Inc. Compositions d'alimentation de médicament à action rapide
DE602005024413D1 (de) 2004-08-20 2010-12-09 Mannkind Corp Katalyse der diketopiperazinsynthese
EP2314298B1 (fr) 2004-08-23 2015-05-27 MannKind Corporation Microparticules comprenant des sels de diketopiperazine permettant l'administration de médicaments
RU2390325C2 (ru) 2005-09-14 2010-05-27 Маннкайнд Корпорейшн Способ приготовления лекарственного препарата, основанный на увеличении сродства активных агентов к поверхностям кристаллических микрочастиц
US7713929B2 (en) 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
US8084420B2 (en) * 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
US20070086952A1 (en) * 2005-09-29 2007-04-19 Biodel, Inc. Rapid Acting and Prolonged Acting Inhalable Insulin Preparations
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WO2009089181A1 (fr) * 2008-01-04 2009-07-16 Blodel, Inc. Préparations d'insuline pour libération d'insuline en fonction de niveaux de glucose dans les tissus
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3835108A (en) * 1972-02-15 1974-09-10 American Home Prod Process for preparing the releasing hormone of luteinizing hormone(lh)and of follicle stimulating hormone(fsh),salts and compositions thereof,and intermediates therefor
US3917825A (en) * 1972-10-12 1975-11-04 Takeda Chemical Industries Ltd Preparation for rectal or vaginal administration containing LH-RH or its analogs
GB1454105A (en) * 1972-11-04 1976-10-27 Hoechst Ag Preparation containing luteinizing hormone-releasing factor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3835108A (en) * 1972-02-15 1974-09-10 American Home Prod Process for preparing the releasing hormone of luteinizing hormone(lh)and of follicle stimulating hormone(fsh),salts and compositions thereof,and intermediates therefor
US3917825A (en) * 1972-10-12 1975-11-04 Takeda Chemical Industries Ltd Preparation for rectal or vaginal administration containing LH-RH or its analogs
GB1454105A (en) * 1972-11-04 1976-10-27 Hoechst Ag Preparation containing luteinizing hormone-releasing factor

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2465486A1 (fr) * 1979-09-21 1981-03-27 Roussel Uclaf Nouvelle application utilisant la lh-rh ou des agonistes
EP0052510A2 (fr) * 1980-11-18 1982-05-26 Syntex (U.S.A.) Inc. Microencapsulation de polypeptides hydrosolubles
EP0052510A3 (en) * 1980-11-18 1982-09-08 Syntex (U.S.A.) Inc. Microencapsulation of water soluble polypeptides
EP0067513A2 (fr) * 1981-05-14 1982-12-22 Takeda Chemical Industries, Ltd. Préparations pharmaceutiques contenant du TRH ou son analogue
EP0067513A3 (en) * 1981-05-14 1983-10-05 Takeda Chemical Industries, Ltd. Pharmaceutical preparations containing trh or its analogue
EP0130409A2 (fr) * 1983-06-07 1985-01-09 Takeda Chemical Industries, Ltd. Corps composite à libération lente et procédé de sa préparation
EP0130409A3 (fr) * 1983-06-07 1986-07-02 Takeda Chemical Industries, Ltd. Corps composite à libération lente et procédé de sa préparation

Also Published As

Publication number Publication date
AU3918378A (en) 1980-02-28
GB2003386B (en) 1982-06-16
GB2003386A (en) 1979-03-14
IT1098199B (it) 1985-09-07
FR2400904B1 (fr) 1982-07-30
CH634992A5 (de) 1983-03-15
IT7826956A0 (it) 1978-08-23
US4211769A (en) 1980-07-08
AU517349B2 (en) 1981-07-23
CA1112570A (fr) 1981-11-17
DE2836631A1 (de) 1979-03-08

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