ES437363A1 - Pharmaceutical compositions - Google Patents
Pharmaceutical compositionsInfo
- Publication number
- ES437363A1 ES437363A1 ES437363A ES437363A ES437363A1 ES 437363 A1 ES437363 A1 ES 437363A1 ES 437363 A ES437363 A ES 437363A ES 437363 A ES437363 A ES 437363A ES 437363 A1 ES437363 A1 ES 437363A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- formula
- hydrogen atom
- substituted
- carbon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Abstract
A procedure for the preparation of new Schiff bases of the formula: **(See formula)** where R1 is a hydrogen atom or a lower alkyl group; R2 and R3 are the same or different and each is a hydrogen or halogen atom, a hydroxy group or a lower alkoxy group, or R2 and R3 are attached to adjacent carbon atoms in the benzene nucleus A and together represent a ring carbocyclic fused to benzene nucleus A; R4 is a hydrogen atom, an alkyl or analkyl group or a substituted or unsubstituted aryl group, or R4 together with R3 form a non-aromatic ring fused to the benzene nucleus A, whose non-aromatic ring may in turn be fused to other rings ; R5 is a hydrogen atom, a lower alkyl group, a lower hydroxyalkyl group, or a carboxylic acid group; R6 is a carbon-carbon or carbon-hydrogen bond, a methylene group (-CH2-), a hydroxymethylene group (-CHCH-) or a mercaptomethylene group (-CHSH) and R7 is a hydrogen atom, an alkyl or substituted alkyl group, an aryl or substituted aryl group, or a heterocyclic or substituted heterocyclic group, the process of which is characterized by reacting a carbonyl compound of formula: **(See formula)** where R1, R2, R3 and R4 have the meaning defined above, with an amine of formula: **(See formula)** where R5, R6 and R7 have the meanings defined above, in the presence of a lower alkanol as solvent. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1915774A GB1529564A (en) | 1974-05-01 | 1974-05-01 | Pharmaceutical compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
ES437363A1 true ES437363A1 (en) | 1977-05-16 |
Family
ID=10124714
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES437363A Expired ES437363A1 (en) | 1974-05-01 | 1975-04-30 | Pharmaceutical compositions |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPS5112933A (en) |
AU (1) | AU502579B2 (en) |
BE (1) | BE828530A (en) |
CA (1) | CA1060438A (en) |
DE (1) | DE2519193A1 (en) |
EG (1) | EG12028A (en) |
ES (1) | ES437363A1 (en) |
FR (1) | FR2282870A1 (en) |
GB (1) | GB1529564A (en) |
NL (1) | NL7505174A (en) |
NZ (1) | NZ177384A (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2418222A2 (en) * | 1975-08-01 | 1979-09-21 | Synthelabo | Alpha-phenyl 2-hydroxy-benzylidene amino-alkanoic acid derivs. - and novel di:phenyl-ketone intermediates, useful as anticonvulsants for treating epilepsy |
JPS52159599U (en) * | 1976-05-27 | 1977-12-03 | ||
JPS5812993Y2 (en) * | 1978-07-19 | 1983-03-12 | 日本鋼管株式会社 | Suspended opening/closing scaffolding device |
FR2475543A1 (en) * | 1980-02-12 | 1981-08-14 | Synthelabo | BENZYLIDENIC DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
FR2544308B1 (en) * | 1983-04-14 | 1985-06-14 | Synthelabo | SUBSTITUTED ETHINS, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS |
NO940195L (en) * | 1993-01-25 | 1994-07-26 | Norsk Hydro As | New connections |
-
1974
- 1974-05-01 GB GB1915774A patent/GB1529564A/en not_active Expired
-
1975
- 1975-04-26 EG EG25475A patent/EG12028A/en active
- 1975-04-29 BE BE155898A patent/BE828530A/en unknown
- 1975-04-30 CA CA225,873A patent/CA1060438A/en not_active Expired
- 1975-04-30 DE DE19752519193 patent/DE2519193A1/en active Pending
- 1975-04-30 FR FR7513529A patent/FR2282870A1/en active Granted
- 1975-04-30 ES ES437363A patent/ES437363A1/en not_active Expired
- 1975-05-01 NL NL7505174A patent/NL7505174A/en not_active Application Discontinuation
- 1975-05-01 AU AU80721/75A patent/AU502579B2/en not_active Expired
- 1975-05-01 NZ NZ17738475A patent/NZ177384A/en unknown
- 1975-05-01 JP JP5308975A patent/JPS5112933A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
DE2519193A1 (en) | 1975-11-20 |
FR2282870B1 (en) | 1978-11-10 |
FR2282870A1 (en) | 1976-03-26 |
CA1060438A (en) | 1979-08-14 |
AU8072175A (en) | 1976-11-04 |
EG12028A (en) | 1978-06-30 |
NZ177384A (en) | 1978-03-06 |
AU502579B2 (en) | 1979-08-02 |
NL7505174A (en) | 1975-11-04 |
BE828530A (en) | 1975-10-29 |
JPS5112933A (en) | 1976-01-31 |
GB1529564A (en) | 1978-10-25 |
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