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ES435110A1 - Procedimiento para la obtencion de compuestos de acido 7b- amino-3-cefem-3-ol-4-carboxilico. - Google Patents

Procedimiento para la obtencion de compuestos de acido 7b- amino-3-cefem-3-ol-4-carboxilico.

Info

Publication number
ES435110A1
ES435110A1 ES435110A ES435110A ES435110A1 ES 435110 A1 ES435110 A1 ES 435110A1 ES 435110 A ES435110 A ES 435110A ES 435110 A ES435110 A ES 435110A ES 435110 A1 ES435110 A1 ES 435110A1
Authority
ES
Spain
Prior art keywords
group
formula
transformed
salt
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES435110A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH269374A external-priority patent/CH601310A5/de
Priority claimed from CH776674A external-priority patent/CH610584A5/de
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES435110A1 publication Critical patent/ES435110A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C313/00—Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C313/02—Sulfinic acids; Derivatives thereof
    • C07C313/04—Sulfinic acids; Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES435110A 1974-02-26 1975-02-26 Procedimiento para la obtencion de compuestos de acido 7b- amino-3-cefem-3-ol-4-carboxilico. Expired ES435110A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH269374A CH601310A5 (en) 1974-02-26 1974-02-26 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn
CH776674A CH610584A5 (en) 1974-02-26 1974-06-05 Process for the preparation of 2-(3-amino-2-oxo-4-sulphonylthio-1- azetidinyl)-3-methylenebutyric acid derivatives
CH1100074 1974-08-12

Publications (1)

Publication Number Publication Date
ES435110A1 true ES435110A1 (es) 1977-03-16

Family

ID=27173851

Family Applications (2)

Application Number Title Priority Date Filing Date
ES435110A Expired ES435110A1 (es) 1974-02-26 1975-02-26 Procedimiento para la obtencion de compuestos de acido 7b- amino-3-cefem-3-ol-4-carboxilico.
ES452915A Expired ES452915A1 (es) 1974-02-26 1976-11-02 Procedimiento para la obtencion de derivados de acido 2-(3- amino-2-oxo-4-tio-1-azetilinil)-3-hidroxi sustituido croto- nico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES452915A Expired ES452915A1 (es) 1974-02-26 1976-11-02 Procedimiento para la obtencion de derivados de acido 2-(3- amino-2-oxo-4-tio-1-azetilinil)-3-hidroxi sustituido croto- nico.

Country Status (21)

Country Link
JP (1) JPS625919B2 (es)
AR (1) AR208538A1 (es)
AT (2) AT337362B (es)
AU (1) AU498131B2 (es)
BE (1) BE825919A (es)
BG (1) BG26201A3 (es)
CA (2) CA1059988A (es)
DD (1) DD117074A5 (es)
DE (1) DE2506330A1 (es)
DK (2) DK73475A (es)
ES (2) ES435110A1 (es)
FI (1) FI66389C (es)
FR (1) FR2261761B1 (es)
GB (1) GB1503581A (es)
HU (1) HU175212B (es)
IE (1) IE40695B1 (es)
IL (1) IL46699A (es)
NL (1) NL7502292A (es)
NO (1) NO750625L (es)
NZ (1) NZ176623A (es)
SE (3) SE431652B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1044247B (it) * 1974-08-02 1980-03-20 Farmaceutici Italia Intermedi per la sintesi di derivati b lattamici e procedimento per la loro preparazone
JPS5198265A (es) * 1975-02-17 1976-08-30
CA1136132A (en) * 1975-02-17 1982-11-23 Teruji Tsuji Cyclization to form cephem ring and intermediates therefor
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
US4029645A (en) * 1975-11-17 1977-06-14 E. R. Squibb & Sons, Inc. Mercury intermediates useful in the preparation of 2-alkoxy cephalosporins
JPH0639474B2 (ja) * 1983-03-04 1994-05-25 大塚化学株式会社 セファロスポリン化合物の製造法
JPS59228854A (ja) * 1983-06-08 1984-12-22 真井　康博 薬液収納兼即効注出器
GB2152497B (en) * 1983-11-28 1987-08-05 Otsuka Kagaku Kk Process for the preparation of azetidinone derivatives
JPS60237061A (ja) * 1984-05-08 1985-11-25 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
JPS60126263A (ja) * 1983-12-12 1985-07-05 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
JPS60115562A (ja) * 1983-11-28 1985-06-22 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
JPS61178961A (ja) * 1985-02-01 1986-08-11 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
DE3725375A1 (de) * 1987-07-31 1989-02-09 Bayer Ag Stabile oxapenem-3-carbonsaeuren
JP3195959B2 (ja) * 1991-03-13 2001-08-06 大塚化学株式会社 ３−ヒドロキシセフェム誘導体の製造法
KR20050087791A (ko) * 2002-11-01 2005-08-31 오키드 케미칼즈 앤드 파마수티컬즈 리미티드 클로로메틸 세펨 유도체 제조를 위한 개선된 제조방법
IN2014CN04530A (es) 2011-12-20 2015-09-11 Hoffmann La Roche
CN104011061B (zh) 2011-12-20 2017-06-13 里博科学有限责任公司 作为hcv rna复制抑制剂的2‘,4’‑二氟‑2‘‑甲基取代的核苷衍生物
CA2912682C (en) 2013-05-16 2021-07-06 Riboscience Llc 4'-fluoro-2'-methyl substituted nucleoside derivatives
KR20160039154A (ko) 2013-05-16 2016-04-08 리보사이언스 엘엘씨 4''-아자이도-3''-데옥시-3''-플루오로 치환된 뉴클레오시드 유도체
US20180200280A1 (en) 2013-05-16 2018-07-19 Riboscience Llc 4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication
EP3684374A4 (en) 2017-09-21 2021-06-16 Riboscience LLC 4'-FLUORO-2'-METHYL SUBSTITUTE NUCLEOSIDE DERIVATIVES USED AS HCV RNA REPLICATION INHIBITORS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2230372A1 (de) * 1972-06-21 1973-01-11 Fujisawa Pharmaceutical Co Verfahren zur herstellung von oxidierten penam-derivaten
SE428022B (sv) * 1972-06-29 1983-05-30 Ciba Geigy Ag 7beta-amino-cefam-3-on-4-karboxylsyraforeningar till anvendning for framstellning av cefalosporinderivat
AR206201A1 (es) * 1972-06-29 1976-07-07 Ciba Geigy Ag Procedimiento para la obtencion de compuestos de acido 7beta-amino-3-cefem-3-01-4-carboxilico0-substituidos

Also Published As

Publication number Publication date
CA1059988A (en) 1979-08-07
SE7807810L (sv) 1978-07-13
AT350068B (de) 1979-05-10
IL46699A (en) 1977-11-30
DD117074A5 (es) 1975-12-20
BE825919A (fr) 1975-08-25
NO750625L (es) 1975-08-27
NZ176623A (en) 1978-04-03
CA1080713A (en) 1980-07-01
HU175212B (hu) 1980-06-28
ATA28178A (de) 1978-10-15
FI66389C (fi) 1984-10-10
BG26201A3 (bg) 1979-02-15
IL46699A0 (en) 1975-04-25
SE438855B (sv) 1985-05-13
FR2261761A1 (es) 1975-09-19
JPS625919B2 (es) 1987-02-07
FI66389B (fi) 1984-06-29
AU7849875A (en) 1976-08-26
DK73475A (es) 1975-10-20
AT337362B (de) 1977-06-27
DK348678A (da) 1978-08-07
AR208538A1 (es) 1977-02-15
SE438854B (sv) 1985-05-13
IE40695B1 (en) 1979-08-01
SE431652B (sv) 1984-02-20
ES452915A1 (es) 1977-11-01
SE7807811L (sv) 1978-07-13
FR2261761B1 (es) 1978-08-18
AU498131B2 (en) 1979-02-15
SE7501317L (es) 1975-08-27
NL7502292A (nl) 1975-08-28
FI750503A (es) 1975-08-27
DE2506330A1 (de) 1975-09-04
JPS50129590A (es) 1975-10-13
GB1503581A (en) 1978-03-15
IE40695L (en) 1975-08-26
ATA108275A (de) 1976-10-15

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