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ES2184097T3 - Nuevos compuestos. - Google Patents

Nuevos compuestos.

Info

Publication number
ES2184097T3
ES2184097T3 ES97927552T ES97927552T ES2184097T3 ES 2184097 T3 ES2184097 T3 ES 2184097T3 ES 97927552 T ES97927552 T ES 97927552T ES 97927552 T ES97927552 T ES 97927552T ES 2184097 T3 ES2184097 T3 ES 2184097T3
Authority
ES
Spain
Prior art keywords
new compounds
phenyll
benzimidazoles
endogenously
french
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97927552T
Other languages
English (en)
Inventor
Kosrat Amin
Mikael Dahlstrom
Peter Nordberg
Ingemar Starke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of ES2184097T3 publication Critical patent/ES2184097T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A DERIVADOS DE BENZIMIDAZOLES DE FORMULA (I), EN LA QUE LA FRACCION DE FENILO ES SUSTITUIDA POR ALQUILO INFERIOR EN LAS POSICIONES 2 Y 6 Y QUE INHIBEN LA SECRECION DE ACIDO GASTRICO ESTIMULADA EXOGENA O ENDOGENAMENTE Y POR TANTO SE PUEDEN UTILIZAR EN LA PREVENCION O TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS GASTROINTESTINALES.
ES97927552T 1996-06-10 1997-06-05 Nuevos compuestos. Expired - Lifetime ES2184097T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9602286A SE9602286D0 (sv) 1996-06-10 1996-06-10 New compounds

Publications (1)

Publication Number Publication Date
ES2184097T3 true ES2184097T3 (es) 2003-04-01

Family

ID=20402945

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97927552T Expired - Lifetime ES2184097T3 (es) 1996-06-10 1997-06-05 Nuevos compuestos.

Country Status (33)

Country Link
US (1) US6465505B1 (es)
EP (1) EP0906288B1 (es)
JP (1) JP2000512291A (es)
CN (1) CN1101385C (es)
AR (1) AR007352A1 (es)
AT (1) ATE227273T1 (es)
AU (1) AU712173B2 (es)
BR (1) BR9709666A (es)
CA (1) CA2256687C (es)
CZ (1) CZ291469B6 (es)
DE (1) DE69716904T2 (es)
DK (1) DK0906288T3 (es)
EE (1) EE03682B1 (es)
ES (1) ES2184097T3 (es)
HK (1) HK1017351A1 (es)
HU (1) HUP0002952A3 (es)
ID (1) ID18431A (es)
IL (1) IL127432A0 (es)
IS (1) IS1864B (es)
MY (1) MY119012A (es)
NO (1) NO311672B1 (es)
NZ (1) NZ332965A (es)
PL (1) PL330525A1 (es)
PT (1) PT906288E (es)
RU (1) RU2184113C2 (es)
SA (1) SA97180427B1 (es)
SE (1) SE9602286D0 (es)
SK (1) SK282704B6 (es)
TR (1) TR199802554T2 (es)
TW (1) TW470742B (es)
UA (1) UA64714C2 (es)
WO (1) WO1997047603A1 (es)
ZA (1) ZA974681B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9704404D0 (sv) 1997-11-28 1997-11-28 Astra Ab New compounds
AR043063A1 (es) * 2002-12-13 2005-07-13 Altana Pharma Ag Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
BRPI0408893A (pt) * 2003-04-04 2006-04-11 Altana Pharma Ag benzimidazóis cìclicos
AR046893A1 (es) * 2003-12-16 2005-12-28 Altana Pharma Ag Bencimidazoles triciclicos
AR048869A1 (es) * 2004-04-26 2006-06-07 Altana Pharma Ag Bencimidazoles triciclicos
AR049168A1 (es) * 2004-05-18 2006-07-05 Altana Pharma Ag Derivados de benzimidazol
AU2005251943A1 (en) * 2004-06-09 2005-12-22 Altana Pharma Ag Substituted tricyclic benzimidazoles
EP1797089A1 (en) * 2004-10-01 2007-06-20 Altana Pharma AG Substituted tricyclic benzimidazoles
AR051041A1 (es) * 2004-10-04 2006-12-13 Altana Pharma Ag Bencimidazoles triciclicos condensados
CA2608582A1 (en) 2005-06-14 2006-12-21 Pfizer Inc. Chromane substituted benzimidazole derivatives as acid pump antagonists
JP2009504798A (ja) * 2005-08-22 2009-02-05 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 同位体置換されたベンゾイミダゾール誘導体
WO2007072142A2 (en) * 2005-12-19 2007-06-28 Pfizer Japan Inc. Benzimidazole-5-carboxamide derivatives
ES2345726T3 (es) * 2005-12-19 2010-09-30 Raqualia Pharma Inc Bencimidazoles sustituidos con cromano y su uso como inhibidores de la bomba acida.
US20080027044A1 (en) * 2006-06-13 2008-01-31 Kim Lewis Prodrug antibiotic screens
WO2008060522A2 (en) * 2006-11-10 2008-05-22 The Regents Of The University Of California Atmospheric pressure plasma-induced graft polymerization
JP2010529194A (ja) * 2007-06-13 2010-08-26 ノースイースタン・ユニバーシティ 抗生物質
WO2008151927A2 (en) * 2007-06-15 2008-12-18 Nycomed Gmbh 6-n-substituted benz imidazole derivatives as acid pump antagonists
US8445076B2 (en) * 2008-06-11 2013-05-21 The Regents Of The University Of California Fouling and scaling resistant nano-structured reverse osmosis membranes
KR101472686B1 (ko) 2013-07-09 2014-12-16 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 제조방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
ES2036600T3 (es) * 1986-10-29 1993-06-01 Dieter Prof. Dr. Binder Procedimiento para preparar 1-(3-(2-dialquilaminoetoxi)-2-tienil)-3-fenil-1-propanonas.
AU2991595A (en) * 1994-08-03 1996-03-04 Fujisawa Pharmaceutical Co., Ltd. Heterocyclic compound
SE9700661D0 (sv) 1997-02-25 1997-02-25 Astra Ab New compounds

Also Published As

Publication number Publication date
JP2000512291A (ja) 2000-09-19
HK1017351A1 (en) 1999-11-19
CZ291469B6 (cs) 2003-03-12
CN1101385C (zh) 2003-02-12
NO311672B1 (no) 2002-01-02
NO985764D0 (no) 1998-12-09
DE69716904D1 (de) 2002-12-12
EE03682B1 (et) 2002-04-15
IS4907A (is) 1998-11-25
HUP0002952A2 (hu) 2001-05-28
AR007352A1 (es) 1999-10-27
BR9709666A (pt) 2000-05-09
MY119012A (en) 2005-03-31
AU712173B2 (en) 1999-10-28
EP0906288A1 (en) 1999-04-07
UA64714C2 (en) 2004-03-15
IS1864B (is) 2003-04-15
EP0906288B1 (en) 2002-11-06
DK0906288T3 (da) 2003-01-06
HUP0002952A3 (en) 2001-11-28
ATE227273T1 (de) 2002-11-15
PL330525A1 (en) 1999-05-24
TR199802554T2 (xx) 1999-03-22
CA2256687A1 (en) 1997-12-18
NZ332965A (en) 2000-05-26
SK165498A3 (en) 1999-06-11
AU3199297A (en) 1998-01-07
SK282704B6 (sk) 2002-11-06
NO985764L (no) 1998-12-09
IL127432A0 (en) 1999-10-28
SA97180427B1 (ar) 2005-10-15
CA2256687C (en) 2005-08-09
TW470742B (en) 2002-01-01
DE69716904T2 (de) 2003-07-24
EE9800430A (et) 1999-06-15
CZ403998A3 (cs) 1999-05-12
RU2184113C2 (ru) 2002-06-27
PT906288E (pt) 2003-02-28
SE9602286D0 (sv) 1996-06-10
US6465505B1 (en) 2002-10-15
ID18431A (id) 1998-04-09
CN1226236A (zh) 1999-08-18
ZA974681B (en) 1998-08-25
WO1997047603A1 (en) 1997-12-18

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