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ES2059140T3 - Procedimiento mejorado y aparato para la introduccion de sustancias biologicas en celulas vivas. - Google Patents

Procedimiento mejorado y aparato para la introduccion de sustancias biologicas en celulas vivas.

Info

Publication number
ES2059140T3
ES2059140T3 ES91909768T ES91909768T ES2059140T3 ES 2059140 T3 ES2059140 T3 ES 2059140T3 ES 91909768 T ES91909768 T ES 91909768T ES 91909768 T ES91909768 T ES 91909768T ES 2059140 T3 ES2059140 T3 ES 2059140T3
Authority
ES
Spain
Prior art keywords
introduction
live cells
biological substances
improved procedure
gas blow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91909768T
Other languages
English (en)
Inventor
Ronald F Bruner
Vit Michael J De
Stephen A Johnston
John C Sanford
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cornell Research Foundation Inc
Duke University
EIDP Inc
Original Assignee
Cornell Research Foundation Inc
EI Du Pont de Nemours and Co
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell Research Foundation Inc, EI Du Pont de Nemours and Co, Duke University filed Critical Cornell Research Foundation Inc
Application granted granted Critical
Publication of ES2059140T3 publication Critical patent/ES2059140T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8206—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by physical or chemical, i.e. non-biological, means, e.g. electroporation, PEG mediated
    • C12N15/8207—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by physical or chemical, i.e. non-biological, means, e.g. electroporation, PEG mediated by mechanical means, e.g. microinjection, particle bombardment, silicon whiskers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Sustainable Development (AREA)
  • Mechanical Engineering (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

SE DESCRIBE UN PROCESO QUE USA UN GOLPE DE GAS FRIO PARA ACELERAR MICROPROYECTILES, EN EL QUE LAS PARTICULAS SE PRESENTAN FRENTE AL GOLPE DE GAS SOBRE UNA SUPERFICIE PLANA PERPENDICULAR AL PLANO DE EXPANSION DE LA ONDA DEL GOLPE DE GAS. SE DESCRIBEN ALGUNOS APARATOS DIFERENTES CAPACES DE LLEVAR A CABO ESTE METODO.
ES91909768T 1990-05-29 1991-04-29 Procedimiento mejorado y aparato para la introduccion de sustancias biologicas en celulas vivas. Expired - Lifetime ES2059140T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/529,989 US5204253A (en) 1990-05-29 1990-05-29 Method and apparatus for introducing biological substances into living cells

Publications (1)

Publication Number Publication Date
ES2059140T3 true ES2059140T3 (es) 1994-11-01

Family

ID=24112008

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91909768T Expired - Lifetime ES2059140T3 (es) 1990-05-29 1991-04-29 Procedimiento mejorado y aparato para la introduccion de sustancias biologicas en celulas vivas.

Country Status (13)

Country Link
US (1) US5204253A (es)
EP (1) EP0535005B1 (es)
JP (1) JP2517813B2 (es)
KR (1) KR960008270B1 (es)
AR (1) AR243603A1 (es)
AT (1) ATE110415T1 (es)
AU (1) AU7878891A (es)
CA (1) CA2083816C (es)
DE (1) DE69103631T2 (es)
DK (1) DK0535005T3 (es)
ES (1) ES2059140T3 (es)
HU (1) HU216738B (es)
WO (1) WO1991018991A1 (es)

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HU216738B (hu) 1999-08-30
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KR960008270B1 (ko) 1996-06-21
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