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EP1853906A4 - Method and apparatus for sample deposition - Google Patents

Method and apparatus for sample deposition

Info

Publication number
EP1853906A4
EP1853906A4 EP06705124A EP06705124A EP1853906A4 EP 1853906 A4 EP1853906 A4 EP 1853906A4 EP 06705124 A EP06705124 A EP 06705124A EP 06705124 A EP06705124 A EP 06705124A EP 1853906 A4 EP1853906 A4 EP 1853906A4
Authority
EP
European Patent Office
Prior art keywords
sample deposition
deposition
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06705124A
Other languages
German (de)
French (fr)
Other versions
EP1853906A1 (en
Inventor
Thomas Covey
Peter Kovarik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nordion Inc
Applied Biosystems Inc
Original Assignee
MDS Inc
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002496481A external-priority patent/CA2496481A1/en
Application filed by MDS Inc, Applera Corp filed Critical MDS Inc
Publication of EP1853906A1 publication Critical patent/EP1853906A1/en
Publication of EP1853906A4 publication Critical patent/EP1853906A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
    • B01L2400/027—Drop detachment mechanisms of single droplets from nozzles or pins electrostatic forces between substrate and tip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed
    • G01N2030/8411—Intermediate storage of effluent, including condensation on surface
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/466—Flow patterns using more than one column with separation columns in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
EP06705124A 2005-02-08 2006-02-08 Method and apparatus for sample deposition Withdrawn EP1853906A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US65136205P 2005-02-08 2005-02-08
CA002496481A CA2496481A1 (en) 2005-02-08 2005-02-09 Method and apparatus for sample deposition
US65120305P 2005-02-10 2005-02-10
PCT/CA2006/000168 WO2006084354A1 (en) 2005-02-08 2006-02-08 Method and apparatus for sample deposition

Publications (2)

Publication Number Publication Date
EP1853906A1 EP1853906A1 (en) 2007-11-14
EP1853906A4 true EP1853906A4 (en) 2010-03-17

Family

ID=36792869

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06705124A Withdrawn EP1853906A4 (en) 2005-02-08 2006-02-08 Method and apparatus for sample deposition

Country Status (3)

Country Link
EP (1) EP1853906A4 (en)
JP (1) JP2008530521A (en)
WO (1) WO2006084354A1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5162650A (en) * 1991-01-25 1992-11-10 Finnigan Corporation Method and apparatus for multi-stage particle separation with gas addition for a mass spectrometer
US20020092366A1 (en) * 2001-01-17 2002-07-18 Ansgar Brock Sample deposition method and system
US20030034450A1 (en) * 1997-05-23 2003-02-20 Karger Barry L. On-line and off-line deposition of liquid samples for matrix assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectroscopy
WO2003037515A1 (en) * 2001-10-26 2003-05-08 Perseptive Biosystems, Inc. Robotic system having positionally adjustable multiple probes

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695555A (en) * 1985-06-12 1987-09-22 Keeffe Andrew F O Liquid chromatographic detector and method
US4980057A (en) * 1989-10-03 1990-12-25 General Electric Company Apparatus for mass spectrometric analysis of liquid chromatographic fractions
AU646072B2 (en) * 1990-08-09 1994-02-03 Arl Applied Research Laboratories Sa Method and apparatus for analytical sample preparation
WO1998053308A1 (en) * 1997-05-23 1998-11-26 Northeastern University On-line liquid sample deposition interface for matrix assisted laser desorption ionization-time of flight (maldi-tof) mass spectroscopy
US6074880A (en) * 1998-08-28 2000-06-13 Transgenomic, Inc. Sample analyte containing solution fraction collection system, and method of use
US6633031B1 (en) * 1999-03-02 2003-10-14 Advion Biosciences, Inc. Integrated monolithic microfabricated dispensing nozzle and liquid chromatography-electrospray system and method
WO2002016927A2 (en) * 2000-08-24 2002-02-28 Newton Scientific, Inc. Sample introduction interface for analytical processing
JP3831867B2 (en) * 2001-02-09 2006-10-11 独立行政法人科学技術振興機構 Sample sorting method and apparatus therefor
JP3705745B2 (en) * 2001-03-05 2005-10-12 学校法人 東洋大学 Micro chemical analysis system
AU2004229440B2 (en) * 2003-04-10 2010-08-12 President And Fellows Of Harvard College Formation and control of fluidic species
JP4447852B2 (en) * 2003-05-29 2010-04-07 株式会社島津製作所 Fraction collector for liquid chromatography
JP4174599B2 (en) * 2003-07-08 2008-11-05 株式会社島津製作所 High-performance liquid chromatograph fractionator

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5162650A (en) * 1991-01-25 1992-11-10 Finnigan Corporation Method and apparatus for multi-stage particle separation with gas addition for a mass spectrometer
US20030034450A1 (en) * 1997-05-23 2003-02-20 Karger Barry L. On-line and off-line deposition of liquid samples for matrix assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectroscopy
US20020092366A1 (en) * 2001-01-17 2002-07-18 Ansgar Brock Sample deposition method and system
WO2003037515A1 (en) * 2001-10-26 2003-05-08 Perseptive Biosystems, Inc. Robotic system having positionally adjustable multiple probes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2006084354A1 *

Also Published As

Publication number Publication date
JP2008530521A (en) 2008-08-07
WO2006084354A1 (en) 2006-08-17
EP1853906A1 (en) 2007-11-14

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20070831

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20100215

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20100514