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EE9500045A - 6-lülilised lämmastikku sisaldavad heteroarüüloksasolidinoonid - Google Patents

6-lülilised lämmastikku sisaldavad heteroarüüloksasolidinoonid

Info

Publication number
EE9500045A
EE9500045A EE9500045A EE9500045A EE9500045A EE 9500045 A EE9500045 A EE 9500045A EE 9500045 A EE9500045 A EE 9500045A EE 9500045 A EE9500045 A EE 9500045A EE 9500045 A EE9500045 A EE 9500045A
Authority
EE
Estonia
Prior art keywords
heteroaryloxazolidinones
membered nitrogen
membered
nitrogen
containing heteroaryloxazolidinones
Prior art date
Application number
EE9500045A
Other languages
English (en)
Inventor
Riedl Bernd
H�bich Dieter
Stolle Andreas
Wild Hanno
Endermann Rainer
Bremm Klaus-Dieter
Kroll Hein-Peter
Labischinski Harald
Schaller Klaus
Werling Hans-Otto
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of EE9500045A publication Critical patent/EE9500045A/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Quinoline Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EE9500045A 1994-07-20 1995-07-19 6-lülilised lämmastikku sisaldavad heteroarüüloksasolidinoonid EE9500045A (et)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4425612A DE4425612A1 (de) 1994-07-20 1994-07-20 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone

Publications (1)

Publication Number Publication Date
EE9500045A true EE9500045A (et) 1996-02-15

Family

ID=6523632

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9500045A EE9500045A (et) 1994-07-20 1995-07-19 6-lülilised lämmastikku sisaldavad heteroarüüloksasolidinoonid

Country Status (28)

Country Link
US (2) US5627181A (et)
EP (1) EP0694543A1 (et)
JP (1) JPH0841056A (et)
KR (1) KR960004344A (et)
CN (1) CN1119647A (et)
AU (1) AU699940B2 (et)
BG (1) BG99790A (et)
CA (1) CA2154025A1 (et)
CO (1) CO4410194A1 (et)
CZ (1) CZ187295A3 (et)
DE (1) DE4425612A1 (et)
DZ (1) DZ1912A1 (et)
EE (1) EE9500045A (et)
FI (1) FI953477A (et)
HR (1) HRP950408A2 (et)
HU (1) HUT75035A (et)
IL (1) IL114626A (et)
MA (1) MA23620A1 (et)
NO (1) NO304468B1 (et)
NZ (1) NZ272597A (et)
PE (1) PE35496A1 (et)
PL (1) PL309686A1 (et)
RO (1) RO115262B1 (et)
SK (1) SK91795A3 (et)
SV (1) SV1995000041A (et)
TN (1) TNSN95082A1 (et)
YU (1) YU49295A (et)
ZA (1) ZA956018B (et)

Families Citing this family (78)

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DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
DE19601265A1 (de) * 1996-01-16 1997-07-17 Bayer Ag 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone
DE19601627A1 (de) * 1996-01-18 1997-07-24 Bayer Ag Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
DE19604223A1 (de) 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
HRP970049A2 (en) 1996-02-06 1998-04-30 Bayer Ag New heteroaryl oxazolidinones
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
AU729415B2 (en) 1996-07-12 2001-02-01 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
ATE227277T1 (de) * 1996-08-21 2002-11-15 Upjohn Co Isoxazoline derivate und ihre verwendung als antimikroben
ES2242280T3 (es) 1997-05-30 2005-11-01 PHARMACIA & UPJOHN COMPANY LLC Agentes antibacterianos de oxazolidinona que contienen funcionalidad tiocarbonilo.
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
DE19802239A1 (de) * 1998-01-22 1999-07-29 Bayer Ag Neue mit Bicyclen substituierte Oxazolidinone
CN1288462A (zh) 1998-01-23 2001-03-21 法玛西雅厄普约翰美国公司 噁唑烷酮组合库、组合物和制备方法
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
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IL140084A0 (en) * 1998-06-05 2002-02-10 Astra Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
CA2334811A1 (en) * 1998-07-14 2000-01-27 Pharmacia & Upjohn Company Oxazolidinones to treat eye infections
US6420349B1 (en) 1998-08-24 2002-07-16 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
JP2002535680A (ja) 1999-01-27 2002-10-22 ファルマシア・アンド・アップジョン・カンパニー 延長因子p活性モジュレーターのアッセイ方法
DE19905278A1 (de) * 1999-02-09 2000-08-10 Bayer Ag Oxazolidinone und ihre Verwendung als antibakterielle Mittel
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
US6514529B2 (en) 2000-03-22 2003-02-04 Pharmacia & Upjohn Company Oxazolidinone tablet formulation
MY127336A (en) 2000-03-22 2006-11-30 Upjohn Co Container for linezolid iv solution
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
EP1289959A1 (en) 2000-06-15 2003-03-12 Pharmacia Corporation Dihydrostilbene alkanoic acid derivatives useful as vitronectin antagonists
US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
EP1301207B1 (en) 2000-06-30 2005-08-10 Pharmacia & Upjohn Company LLC Compositions for treating bacterial infections, containing an oxazolidinone compound, sulbactam and and ampicillin
PE20020300A1 (es) * 2000-08-22 2002-05-10 Pharmacia Corp Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco
WO2002018354A1 (en) * 2000-08-31 2002-03-07 Abbott Laboratories Oxazolidinones and their use as antibacterial agents
PE20020578A1 (es) 2000-10-10 2002-08-14 Upjohn Co Una composicion de antibiotico topico para el tratamiento de infecciones oculares
ES2256331T3 (es) 2000-12-21 2006-07-16 PHARMACIA & UPJOHN COMPANY LLC Derivados de quinolina antimicrobianos y uso de los mismos para tratar infecciones bacterianas.
WO2003027083A1 (en) * 2001-04-17 2003-04-03 Merck & Co., Inc. Bicyclo[3,1,0]hexane containing oxazolidinone antibiotic and derivatives thereof
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US20040019012A1 (en) * 2002-02-22 2004-01-29 Singh Satish K. Ophthalmic antibiotic drug formulations containing a cyclodextrin compound and cetyl pyridinium chloride
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
JP2005527575A (ja) * 2002-03-29 2005-09-15 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 糖尿病性足病変感染を治療するためのオキサゾリジノンの非経口、静脈内および経口投与
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DE60304360T2 (de) * 2002-08-12 2006-11-16 Pharmacia & Upjohn Co. Llc, Kalamazoo N-aryl-2-oxazolidinone und deren derivate
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US20040191326A1 (en) * 2003-03-31 2004-09-30 Reo Joseph P. Taste-masking vehicle for coated oxazolidinone particles
US20040204463A1 (en) * 2003-04-01 2004-10-14 Harris Christina Renee N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
US20060270680A1 (en) * 2003-06-03 2006-11-30 Goldberg Joel A Sulfonamide compounds and methods of making and using the same
TWI454465B (zh) 2003-06-03 2014-10-01 Melinta Therapeutics Inc 聯芳基雜環化合物及製法及其用途
WO2005012271A2 (en) * 2003-07-29 2005-02-10 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
NZ544237A (en) * 2003-07-02 2008-09-26 Merck & Co Inc Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof
JP2007521284A (ja) * 2003-07-02 2007-08-02 メルク アンド カンパニー インコーポレーテッド オキサゾリジノン系抗生物質及びその誘導体
CA2529293A1 (en) * 2003-07-02 2005-01-20 Merck & Co., Inc. Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof
ES2536001T3 (es) * 2003-07-29 2015-05-19 Melinta Therapeutics, Inc. Procedimiento para la síntesis de biariloxazolidinonas
US20070197541A1 (en) * 2003-07-29 2007-08-23 Oyelere Adegboyega K Biaryl heterocyclic amines,amides, and sulfur-containing compounds and methods of making and using the same
WO2005019214A1 (en) * 2003-08-25 2005-03-03 Warner-Lambert Company Llc Novel antimicrobial aryloxazolidinone compounds
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
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Also Published As

Publication number Publication date
NZ272597A (en) 1997-01-29
PE35496A1 (es) 1996-10-14
MA23620A1 (fr) 1996-04-01
HRP950408A2 (en) 1997-04-30
CN1119647A (zh) 1996-04-03
NO952865D0 (no) 1995-07-19
TNSN95082A1 (fr) 1996-02-06
US5843967A (en) 1998-12-01
SV1995000041A (es) 1996-03-28
FI953477A0 (fi) 1995-07-18
PL309686A1 (en) 1996-01-22
CA2154025A1 (en) 1996-01-21
ZA956018B (en) 1996-03-13
NO304468B1 (no) 1998-12-21
BG99790A (en) 1996-04-30
CO4410194A1 (es) 1997-01-09
IL114626A (en) 1999-08-17
IL114626A0 (en) 1995-11-27
YU49295A (sh) 1998-12-23
NO952865L (no) 1996-01-22
RO115262B1 (ro) 1999-12-30
AU2498595A (en) 1996-02-01
EP0694543A1 (de) 1996-01-31
CZ187295A3 (en) 1996-02-14
KR960004344A (ko) 1996-02-23
HU9502173D0 (en) 1995-09-28
FI953477A (fi) 1996-01-21
DZ1912A1 (fr) 2002-02-17
JPH0841056A (ja) 1996-02-13
AU699940B2 (en) 1998-12-17
SK91795A3 (en) 1996-02-07
DE4425612A1 (de) 1996-04-04
HUT75035A (en) 1997-03-28
US5627181A (en) 1997-05-06

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