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EA201291328A1 - АНТИТЕЛА К ФРАГМЕНТУ C3d КОМПОНЕНТА КОМПЛЕМЕНТА 3 - Google Patents

АНТИТЕЛА К ФРАГМЕНТУ C3d КОМПОНЕНТА КОМПЛЕМЕНТА 3

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Publication number
EA201291328A1
EA201291328A1 EA201291328A EA201291328A EA201291328A1 EA 201291328 A1 EA201291328 A1 EA 201291328A1 EA 201291328 A EA201291328 A EA 201291328A EA 201291328 A EA201291328 A EA 201291328A EA 201291328 A1 EA201291328 A1 EA 201291328A1
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EA
Eurasian Patent Office
Prior art keywords
materials
methods
complement cascade
modulating
host
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EA201291328A
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English (en)
Inventor
В. Майкл Холерз
Джошуа М. Термен
Людмила Кулик
Original Assignee
Дзе Риджентс Оф Дзе Юниверсити Оф Колорадо, Э Боди Корпорейт
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Publication of EA201291328A1 publication Critical patent/EA201291328A1/ru

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Abstract

Изобретение относится к способам и материалам для модулирования альтернативного каскада комплемента (САР), классического каскада комплемента (ССР), лектинового/маннозного каскада комплемента (СМР) или их сочетаний, а также способы и материалы для направления диагностических, профилактических и терапевтических средств в локализованные области ткани в организме, где они могут более непосредственно оказывать свое действие на предназначенные для этого клетки-мишени или ткань, со снижением связанных с ними системных эффектов по сравнению с введением тех же или сходных средств ненаправленным системным путем. Поэтому способы и материалы по настоящему изобретению могут обеспечивать повышенную эффективность, более низкие предельно эффективные дозировки, и/или более низкие эффективные поддерживающие дозы, и/или сниженные связанные нежелательные или побочные эффекты в аспекте частоты их возникновения или тяжести, или в обоих аспектах. Настоящее изобретение также относится к способам и материалам для модулирования гуморального иммунного ответа хозяина, в особенности, для снижения ингибирования или предотвращения гуморального иммунного ответа хозяина.
EA201291328A 2010-06-22 2011-06-22 АНТИТЕЛА К ФРАГМЕНТУ C3d КОМПОНЕНТА КОМПЛЕМЕНТА 3 EA201291328A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35749910P 2010-06-22 2010-06-22
PCT/US2011/041517 WO2011163412A1 (en) 2010-06-22 2011-06-22 Antibodies to the c3d fragment of complement component 3

Publications (1)

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EA201291328A1 true EA201291328A1 (ru) 2013-10-30

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EA201291328A EA201291328A1 (ru) 2010-06-22 2011-06-22 АНТИТЕЛА К ФРАГМЕНТУ C3d КОМПОНЕНТА КОМПЛЕМЕНТА 3

Country Status (14)

Country Link
US (3) US9815890B2 (ru)
EP (1) EP2585110A4 (ru)
JP (1) JP2013533243A (ru)
KR (1) KR20130036276A (ru)
CN (1) CN103249432A (ru)
AU (1) AU2011270959A1 (ru)
BR (1) BR112012033119A2 (ru)
CA (1) CA2803588A1 (ru)
CO (1) CO6680613A2 (ru)
EA (1) EA201291328A1 (ru)
MX (1) MX2012014975A (ru)
SG (1) SG186397A1 (ru)
WO (1) WO2011163412A1 (ru)
ZA (1) ZA201209430B (ru)

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MX2012014975A (es) 2013-03-12
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US20130078245A1 (en) 2013-03-28
CA2803588A1 (en) 2011-12-29
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