EA201070746A1 - Фармацевтическая композиция, содержащая по меньшей мере один белковый активный ингредиент, защищенный от расщепления ферментами - Google Patents
Фармацевтическая композиция, содержащая по меньшей мере один белковый активный ингредиент, защищенный от расщепления ферментамиInfo
- Publication number
- EA201070746A1 EA201070746A1 EA201070746A EA201070746A EA201070746A1 EA 201070746 A1 EA201070746 A1 EA 201070746A1 EA 201070746 A EA201070746 A EA 201070746A EA 201070746 A EA201070746 A EA 201070746A EA 201070746 A1 EA201070746 A1 EA 201070746A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- protein active
- active ingredient
- ingredient
- pharmaceutical composition
- composition containing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Данное изобретение относится к фармацевтическим композициям, содержащим по меньшей мере один белковый активный ингредиент, защищенный от пищеварительных ферментов. Указанные фармацевтические композиции содержат указанный по меньшей мере один белковый активный ингредиент в свободной форме, а также для жидкостей содержат системы, способные их буферизовать при рН больше 4 и меньше или равном 8, или для твердых веществ содержат системы, которые при помещении их в жидкую среду оказывают буферный эффект между рН больше 4 и рН меньше или равном 8.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0759971A FR2925333B1 (fr) | 2007-12-19 | 2007-12-19 | Compositions pharmaceutiques renfermant au moins un principe actif proteinique protege des enzymes digestives |
PCT/FR2008/052357 WO2009083686A1 (fr) | 2007-12-19 | 2008-12-18 | Compositions pharmaceutiques renfermant au moins un principe actif proteinique protege des enzymes digestives |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201070746A1 true EA201070746A1 (ru) | 2011-02-28 |
EA023107B1 EA023107B1 (ru) | 2016-04-29 |
Family
ID=39671377
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201070746A EA023107B1 (ru) | 2007-12-19 | 2008-12-18 | Фармацевтическая композиция, содержащая по меньшей мере один белковый активный ингредиент, защищенный от расщепления ферментами |
Country Status (19)
Country | Link |
---|---|
US (1) | US8309123B2 (ru) |
EP (1) | EP2234598A1 (ru) |
JP (1) | JP5676272B2 (ru) |
KR (2) | KR101592609B1 (ru) |
CN (1) | CN101917967B (ru) |
AP (1) | AP3573A (ru) |
AR (1) | AR069847A1 (ru) |
AU (1) | AU2008345474B2 (ru) |
BR (1) | BRPI0821373B8 (ru) |
CA (1) | CA2709899C (ru) |
EA (1) | EA023107B1 (ru) |
FR (1) | FR2925333B1 (ru) |
HK (1) | HK1146386A1 (ru) |
IL (1) | IL206364A (ru) |
MA (1) | MA31927B1 (ru) |
MX (1) | MX2010006927A (ru) |
TN (1) | TN2010000290A1 (ru) |
TW (1) | TWI461226B (ru) |
WO (1) | WO2009083686A1 (ru) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011094632A1 (en) * | 2010-01-29 | 2011-08-04 | The Uab Research Foundation | Method for administration of insulin and pharmaceutical composition thereof |
US9962336B2 (en) | 2014-05-01 | 2018-05-08 | Sun Pharmaceutical Industries Limited | Extended release suspension compositions |
PL3137060T5 (pl) | 2014-05-01 | 2024-04-08 | Sun Pharmaceutical Industries Ltd | Kompozycje zawiesinowe o przedłużonym uwalnianiu |
US10258583B2 (en) | 2014-05-01 | 2019-04-16 | Sun Pharmaceutical Industries Limited | Extended release liquid compositions of guanfacine |
US20180104197A9 (en) | 2014-05-01 | 2018-04-19 | Sun Pharmaceutical Industries Limited | Extended release liquid compositions of metformin |
MX2017001332A (es) | 2014-07-30 | 2017-08-02 | Sun Pharmaceutical Ind Ltd | Envase con camara.doble. |
CN107205928B (zh) * | 2014-11-04 | 2021-05-11 | 因华生技制药股份有限公司 | 不稳定或难溶药物的口服投予 |
US10238803B2 (en) | 2016-05-02 | 2019-03-26 | Sun Pharmaceutical Industries Limited | Drug delivery device for pharmaceutical compositions |
US10369078B2 (en) | 2016-05-02 | 2019-08-06 | Sun Pharmaceutical Industries Limited | Dual-chamber pack for pharmaceutical compositions |
FR3120189A1 (fr) * | 2021-03-01 | 2022-09-02 | Farid Bennis | Composition pharmaceutique pour une administration par voie orale d’un agoniste du récepteur du GLP-1 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
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IE36225B1 (en) * | 1971-01-28 | 1976-09-15 | Nat Res Dev | Improvements relating to insulin derivatives |
US4692433A (en) * | 1983-10-12 | 1987-09-08 | The Regents Of The University Of California | Method and composition for regulating serum calcium levels of mammals |
EP0179904A1 (en) | 1984-05-09 | 1986-05-07 | Medaphore Inc. | Oral insulin and a method of making the same |
US4693433A (en) * | 1986-06-06 | 1987-09-15 | Merrill David Martin | Unwind stand for web rolls |
US6191105B1 (en) * | 1993-05-10 | 2001-02-20 | Protein Delivery, Inc. | Hydrophilic and lipophilic balanced microemulsion formulations of free-form and/or conjugation-stabilized therapeutic agents such as insulin |
GB9417524D0 (en) * | 1994-08-31 | 1994-10-19 | Cortecs Ltd | Pharmaceutical compositions |
WO1996006632A1 (en) * | 1994-09-01 | 1996-03-07 | Allied Medical Research Associates | Compositions and methods for delivery of polypeptides |
US5824638A (en) | 1995-05-22 | 1998-10-20 | Shire Laboratories, Inc. | Oral insulin delivery |
US5912014A (en) * | 1996-03-15 | 1999-06-15 | Unigene Laboratories, Inc. | Oral salmon calcitonin pharmaceutical products |
US5783556A (en) * | 1996-08-13 | 1998-07-21 | Genentech, Inc. | Formulated insulin-containing composition |
US6071539A (en) * | 1996-09-20 | 2000-06-06 | Ethypharm, Sa | Effervescent granules and methods for their preparation |
WO1999016417A1 (en) * | 1997-10-01 | 1999-04-08 | Flemington Pharmaceutical Corporation | Buccal, polar and non-polar spray or capsule |
SE9801495D0 (sv) * | 1998-04-28 | 1998-04-28 | Astra Ab | Protein formulationa |
US6531648B1 (en) * | 1998-12-17 | 2003-03-11 | Syngenta Participations Ag | Grain processing method and transgenic plants useful therein |
ES2173679T3 (es) * | 1999-01-27 | 2002-10-16 | Idea Ag | Inmunizacion/transporte transnasal con vehiculos altamente adaptables. |
SE9904121D0 (sv) * | 1999-11-15 | 1999-11-15 | Gustaf Jederstroem | Hydrophobe biomolecular structure |
US6531112B2 (en) * | 2000-05-15 | 2003-03-11 | Delrx Pharmaceutical Corporation | Formulations for administering calcitonin and processes for preparing the same |
US7060675B2 (en) * | 2001-02-15 | 2006-06-13 | Nobex Corporation | Methods of treating diabetes mellitus |
US7316819B2 (en) * | 2001-03-08 | 2008-01-08 | Unigene Laboratories, Inc. | Oral peptide pharmaceutical dosage form and method of production |
CN1335182A (zh) * | 2001-08-08 | 2002-02-13 | 华中科技大学 | 胰岛素口腔喷剂及其制备工艺 |
GB0119859D0 (en) * | 2001-08-15 | 2001-10-10 | Qinetiq Ltd | Eye tracking system |
US20060258561A1 (en) * | 2003-03-13 | 2006-11-16 | Novo Nordisk A/S | Novel NPH insulin preparations |
KR100638041B1 (ko) * | 2003-12-24 | 2006-10-23 | 주식회사 삼양사 | 수용성 약물의 경구투여용 나노입자 조성물 및 그의제조방법 |
WO2005113008A1 (en) * | 2004-05-21 | 2005-12-01 | Mediplex Corp. | Delivery agents for enhancing mucosal absorption of therapeutic agents |
PT2626368T (pt) * | 2004-07-19 | 2017-03-10 | Biocon Ltd | Conjugados de insulina-oligómero, formulaçôes e usos dos mesmos |
WO2006017541A2 (en) * | 2004-08-03 | 2006-02-16 | Emisphere Technologies, Inc. | Antidiabetic oral insulin-biguanide combination |
AU2006249480A1 (en) | 2005-05-23 | 2006-11-30 | Sdg, Inc. | Lipid construct for delivery of insulin to a mammal |
CA2621641C (en) * | 2005-09-15 | 2014-10-21 | Council Of Scientific And Industrial Research | Ph sensitive nanoparticle formulation for oral delivery of proteins/peptides |
EP1957113A4 (en) * | 2005-11-21 | 2011-11-09 | Medivas Llc | POLYMER PARTICLES FOR THE OUTPUT OF MACROMOLECULES AND METHOD OF APPLICATION THEREFOR |
US8927015B2 (en) * | 2006-04-12 | 2015-01-06 | Emisphere Technologies, Inc. | Formulations for delivering insulin |
-
2007
- 2007-12-19 FR FR0759971A patent/FR2925333B1/fr active Active
-
2008
- 2008-12-18 CN CN200880125189XA patent/CN101917967B/zh active Active
- 2008-12-18 MX MX2010006927A patent/MX2010006927A/es active IP Right Grant
- 2008-12-18 KR KR1020107013390A patent/KR101592609B1/ko active IP Right Grant
- 2008-12-18 JP JP2010538869A patent/JP5676272B2/ja active Active
- 2008-12-18 AP AP2010005298A patent/AP3573A/xx active
- 2008-12-18 WO PCT/FR2008/052357 patent/WO2009083686A1/fr active Application Filing
- 2008-12-18 KR KR1020157032578A patent/KR20150132887A/ko not_active Application Discontinuation
- 2008-12-18 CA CA2709899A patent/CA2709899C/fr active Active
- 2008-12-18 AU AU2008345474A patent/AU2008345474B2/en active Active
- 2008-12-18 EP EP08867946A patent/EP2234598A1/fr active Pending
- 2008-12-18 BR BRPI0821373A patent/BRPI0821373B8/pt active IP Right Grant
- 2008-12-18 EA EA201070746A patent/EA023107B1/ru unknown
- 2008-12-19 US US12/339,310 patent/US8309123B2/en active Active
- 2008-12-19 AR ARP080105568A patent/AR069847A1/es unknown
- 2008-12-19 TW TW097149879A patent/TWI461226B/zh not_active IP Right Cessation
-
2010
- 2010-06-14 IL IL206364A patent/IL206364A/en active IP Right Grant
- 2010-06-18 TN TN2010000290A patent/TN2010000290A1/fr unknown
- 2010-06-18 MA MA32934A patent/MA31927B1/fr unknown
-
2011
- 2011-01-19 HK HK11100516.2A patent/HK1146386A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
IL206364A (en) | 2016-12-29 |
WO2009083686A9 (fr) | 2009-10-15 |
WO2009083686A1 (fr) | 2009-07-09 |
CN101917967A (zh) | 2010-12-15 |
AU2008345474B2 (en) | 2014-07-31 |
IL206364A0 (en) | 2010-12-30 |
JP5676272B2 (ja) | 2015-02-25 |
CA2709899A1 (fr) | 2009-07-09 |
TN2010000290A1 (fr) | 2011-11-11 |
CN101917967B (zh) | 2013-05-22 |
EP2234598A1 (fr) | 2010-10-06 |
KR20100095449A (ko) | 2010-08-30 |
BRPI0821373B1 (pt) | 2020-04-22 |
TWI461226B (zh) | 2014-11-21 |
MA31927B1 (fr) | 2010-12-01 |
FR2925333B1 (fr) | 2012-04-13 |
MX2010006927A (es) | 2010-12-06 |
AU2008345474A1 (en) | 2009-07-09 |
BRPI0821373A2 (pt) | 2015-06-16 |
BRPI0821373B8 (pt) | 2021-05-25 |
KR20150132887A (ko) | 2015-11-26 |
CA2709899C (fr) | 2018-01-16 |
US20090176691A1 (en) | 2009-07-09 |
HK1146386A1 (en) | 2011-06-03 |
TW200940107A (en) | 2009-10-01 |
AP3573A (en) | 2016-02-08 |
JP2011506587A (ja) | 2011-03-03 |
AP2010005298A0 (en) | 2010-06-30 |
AR069847A1 (es) | 2010-02-24 |
KR101592609B1 (ko) | 2016-02-05 |
EA023107B1 (ru) | 2016-04-29 |
US8309123B2 (en) | 2012-11-13 |
FR2925333A1 (fr) | 2009-06-26 |
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