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EA200501837A1 - Система обнаружения полинуклеотидов - Google Patents

Система обнаружения полинуклеотидов

Info

Publication number
EA200501837A1
EA200501837A1 EA200501837A EA200501837A EA200501837A1 EA 200501837 A1 EA200501837 A1 EA 200501837A1 EA 200501837 A EA200501837 A EA 200501837A EA 200501837 A EA200501837 A EA 200501837A EA 200501837 A1 EA200501837 A1 EA 200501837A1
Authority
EA
Eurasian Patent Office
Prior art keywords
dye
polynucleotide
mixture
change
target
Prior art date
Application number
EA200501837A
Other languages
English (en)
Other versions
EA009302B1 (ru
Inventor
Хизер Кошински
Майкл С. Звик
К. Йён Чой
Original Assignee
Инвестиген, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Инвестиген, Инк. filed Critical Инвестиген, Инк.
Publication of EA200501837A1 publication Critical patent/EA200501837A1/ru
Publication of EA009302B1 publication Critical patent/EA009302B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Настоящее изобретение обносится к способам обнаружения присутствия или количества мишеневого полинуклеотида. Полинуклеотид, аналог мишеневой нуклеиновой кислоты и краситель объединяют для образования смеси. Оптическая характеристика красителя сравнивается с эталонным значением скорости изменения оптической характеристики красителя в подобной смеси, содержащей известное количество гибрида мишеневый полинуклеотид/аналог нуклеиновой кислоты, для определения относительной скорости изменения оптической характеристики. Относительная скорость изменения оптической характеристики красителя в смеси коррелируется с присутствием или количеством определённого мишеневого полинуклеотида в образце.
EA200501837A 2003-05-20 2004-05-20 Система обнаружения полинуклеотидов EA009302B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47182703P 2003-05-20 2003-05-20
PCT/US2004/016118 WO2005017181A2 (en) 2003-05-20 2004-05-20 System for detecting polynucleotides

Publications (2)

Publication Number Publication Date
EA200501837A1 true EA200501837A1 (ru) 2006-10-27
EA009302B1 EA009302B1 (ru) 2007-12-28

Family

ID=34193014

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200501837A EA009302B1 (ru) 2003-05-20 2004-05-20 Система обнаружения полинуклеотидов

Country Status (14)

Country Link
US (2) US7745119B2 (ru)
EP (1) EP1631677B1 (ru)
JP (1) JP4633716B2 (ru)
CN (1) CN1894423A (ru)
AT (1) ATE488604T1 (ru)
AU (1) AU2004265581B2 (ru)
BR (1) BRPI0410780A (ru)
CA (1) CA2528843A1 (ru)
DE (1) DE602004030114D1 (ru)
EA (1) EA009302B1 (ru)
GB (1) GB2422196B (ru)
MX (1) MXPA05012482A (ru)
WO (1) WO2005017181A2 (ru)
ZA (1) ZA200510299B (ru)

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Also Published As

Publication number Publication date
GB2422196B (en) 2008-05-07
ATE488604T1 (de) 2010-12-15
DE602004030114D1 (de) 2010-12-30
CN1894423A (zh) 2007-01-10
JP2007525948A (ja) 2007-09-13
GB0525533D0 (en) 2006-01-25
JP4633716B2 (ja) 2011-02-16
EP1631677A2 (en) 2006-03-08
AU2004265581A1 (en) 2005-02-24
CA2528843A1 (en) 2005-02-24
AU2004265581B2 (en) 2008-06-05
US20060147958A1 (en) 2006-07-06
EA009302B1 (ru) 2007-12-28
EP1631677B1 (en) 2010-11-17
BRPI0410780A (pt) 2006-06-27
GB2422196A (en) 2006-07-19
EP1631677A4 (en) 2007-05-02
WO2005017181A2 (en) 2005-02-24
US20110008905A1 (en) 2011-01-13
MXPA05012482A (es) 2006-07-03
US7745119B2 (en) 2010-06-29
ZA200510299B (en) 2007-05-30
WO2005017181A3 (en) 2006-08-10

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