US20030225150A1
(en)
*
|
1997-04-21 |
2003-12-04 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and a topoisomerase II inhibitor as a combination therapy in the treatment of neoplasia
|
US20040072889A1
(en)
*
|
1997-04-21 |
2004-04-15 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
|
PA8469301A1
(es)
|
1998-04-10 |
2000-09-29 |
Pfizer Prod Inc |
Procedimientos para la preparacion de acidos hidroxamicos.
|
GT199900044A
(es)
*
|
1998-04-10 |
2000-09-14 |
|
Procedimientos para preparar haluros de fenoxifenilsulfonilo.
|
PA8469601A1
(es)
|
1998-04-10 |
2000-09-29 |
Pfizer Prod Inc |
Procedimiento para alquilar sulfonamidas impedidas estericamente
|
US20030203956A1
(en)
*
|
1998-12-23 |
2003-10-30 |
Masterrer Jaime L. |
Method of using a cyclooxygenase-2 inhibitor and one or more ornithine decarboxylase inhibitors as a combination therapy in the treatment of neoplasia
|
US20030013739A1
(en)
*
|
1998-12-23 |
2003-01-16 |
Pharmacia Corporation |
Methods of using a combination of cyclooxygenase-2 selective inhibitors and thalidomide for the treatment of neoplasia
|
US20020103141A1
(en)
*
|
1998-12-23 |
2002-08-01 |
Mckearn John P. |
Antiangiogenic combination therapy for the treatment of cancer
|
US6833373B1
(en)
|
1998-12-23 |
2004-12-21 |
G.D. Searle & Co. |
Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
|
US20040053900A1
(en)
*
|
1998-12-23 |
2004-03-18 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and an aromatase inhibitor as a combination therapy
|
US20030119895A1
(en)
*
|
1998-12-23 |
2003-06-26 |
Pharmacia Corporation |
Methods using a combination of a 3-heteroaryl-2-indolinone and a cyclooxygenase-2 inhibitor for the treatment of neoplasia
|
US20040122011A1
(en)
*
|
1998-12-23 |
2004-06-24 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy
|
US6858598B1
(en)
|
1998-12-23 |
2005-02-22 |
G. D. Searle & Co. |
Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
|
UA74803C2
(uk)
|
1999-11-11 |
2006-02-15 |
Осі Фармасьютікалз, Інк. |
Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
|
PL217921B1
(pl)
|
2001-01-05 |
2014-09-30 |
Amgen Fremont Inc |
Przeciwciało przeciw receptorowi insulinopodobnego czynnika wzrostu I, zawierająca go kompozycja farmaceutyczna, sposób jego wytwarzania, zastosowania, linia komórkowa, wyizolowana cząsteczka kwasu nukleinowego, wektor, komórka gospodarza oraz zwierzę transgeniczne
|
US6995171B2
(en)
|
2001-06-21 |
2006-02-07 |
Agouron Pharmaceuticals, Inc. |
Bicyclic pyrimidine and pyrimidine derivatives useful as anticancer agents
|
AR039067A1
(es)
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
Anticuerpos para cd40
|
JPWO2003045433A1
(ja)
*
|
2001-11-29 |
2005-04-07 |
日本オルガノン株式会社 |
心機能不全治療薬
|
AU2003206068A1
(en)
|
2002-03-01 |
2003-09-16 |
Pfizer Inc. |
Indolyl-urea derivatives of thienopyridines useful as anti-angiogenic agents
|
ES2335276T3
(es)
|
2002-03-13 |
2010-03-24 |
Array Biopharma, Inc. |
Derivados de bencimidazol alquilado n3 como inhibidores de mek.
|
UA77303C2
(en)
|
2002-06-14 |
2006-11-15 |
Pfizer |
Derivatives of thienopyridines substituted by benzocondensed heteroarylamide useful as therapeutic agents, pharmaceutical compositions and methods for their use
|
CN1747950A
(zh)
|
2002-12-19 |
2006-03-15 |
美国辉瑞有限公司 |
用于治疗眼病的作为蛋白激酶抑制剂的2-(1h-吲唑-6-基氨基)-苯甲酰胺化合物
|
JP4695588B2
(ja)
|
2003-02-26 |
2011-06-08 |
スージェン, インク. |
プロテインキナーゼ阻害剤としてのアミノヘテロアリール化合物
|
CA2536321A1
(fr)
|
2003-08-29 |
2005-03-10 |
Pfizer Inc. |
Thienopyridine-phenylacetamides et leurs derives utiles comme nouveaux agents anti-angiogeniques
|
US7144907B2
(en)
|
2003-09-03 |
2006-12-05 |
Array Biopharma Inc. |
Heterocyclic inhibitors of MEK and methods of use thereof
|
AR045563A1
(es)
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
Anticuerpos dirigidos a m-csf
|
WO2005051302A2
(fr)
|
2003-11-19 |
2005-06-09 |
Array Biopharma Inc. |
Inhibiteurs bicycliques de mek, et leurs procedes d'utilisation
|
JP4864719B2
(ja)
*
|
2003-11-26 |
2012-02-01 |
ファイザー・プロダクツ・インク |
Gsk−3インヒビターとしてのアミノピラゾール誘導体
|
AU2005276135B2
(en)
|
2004-08-26 |
2011-04-28 |
Pfizer Inc. |
Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors
|
MY146381A
(en)
|
2004-12-22 |
2012-08-15 |
Amgen Inc |
Compositions and methods relating relating to anti-igf-1 receptor antibodies
|
US7429667B2
(en)
|
2005-01-20 |
2008-09-30 |
Ardea Biosciences, Inc. |
Phenylamino isothiazole carboxamidines as MEK inhibitors
|
SA06270141B1
(ar)
|
2005-05-18 |
2009-11-15 |
اراي بيوفارما انك |
مثبطات حلقية غير متجانسة لـmek وطرق استخدامها
|
US8101799B2
(en)
|
2005-07-21 |
2012-01-24 |
Ardea Biosciences |
Derivatives of N-(arylamino) sulfonamides as inhibitors of MEK
|
WO2009018238A1
(fr)
|
2007-07-30 |
2009-02-05 |
Ardea Biosciences, Inc. |
Combinaisons d'inhibiteurs de mek et d'inhibiteurs de raf kinase et leurs utilisations
|
ATE533057T1
(de)
|
2005-09-20 |
2011-11-15 |
Osi Pharm Inc |
Biologische marker als prädiktoren der antikrebsreaktion auf insulinähnlichen wachstumsfaktor-1-rezeptor-kinaseinhibitoren
|
TWI405756B
(zh)
|
2005-12-21 |
2013-08-21 |
Array Biopharma Inc |
新穎硫酸氫鹽
|
WO2007121269A2
(fr)
|
2006-04-11 |
2007-10-25 |
Ardea Biosciences, Inc. |
N-aryl-n'alkyle sulfamides utilisés comme inhibiteurs de mek
|
DE602007009663D1
(de)
|
2006-04-18 |
2010-11-18 |
Ardea Biosciences Inc |
Pyridonsulfonamide und pyridonsulfamide als mek-hemmer
|
CA2672815A1
(fr)
|
2006-12-15 |
2008-06-26 |
Pfizer Products Inc. |
Derives du benzamidazole
|
MX2009007661A
(es)
|
2007-01-19 |
2009-12-14 |
Ardea Biosciences Inc |
Inhibidores de mek.
|
KR101132880B1
(ko)
|
2007-04-18 |
2012-06-28 |
화이자 프로덕츠 인크. |
비정상적인 세포 성장의 치료를 위한 술포닐 아미드 유도체
|
US8530463B2
(en)
|
2007-05-07 |
2013-09-10 |
Hale Biopharma Ventures Llc |
Multimodal particulate formulations
|
EP2690101B1
(fr)
|
2007-12-19 |
2015-06-24 |
Genentech, Inc. |
5-anilinoimidazopyridines et procédés d'utilisation
|
CA2708176A1
(fr)
|
2007-12-21 |
2009-07-02 |
Genentech, Inc. |
Azaindolizines et procedes d'utilisation
|
BRPI0906474A2
(pt)
|
2008-01-04 |
2015-07-14 |
Intellikine Inc |
Certas entidades químicas, composições e métodos
|
US8193182B2
(en)
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
US8637542B2
(en)
|
2008-03-14 |
2014-01-28 |
Intellikine, Inc. |
Kinase inhibitors and methods of use
|
ES2586032T3
(es)
|
2008-03-28 |
2016-10-11 |
Hale Biopharma Ventures, Llc |
Administración de composiciones de benzodiazepinas
|
US9096611B2
(en)
|
2008-07-08 |
2015-08-04 |
Intellikine Llc |
Kinase inhibitors and methods of use
|
JP5836125B2
(ja)
|
2008-10-16 |
2015-12-24 |
ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション |
高分子量メラノーマ関連抗原に対する完全ヒト抗体およびその使用
|
US8476282B2
(en)
|
2008-11-03 |
2013-07-02 |
Intellikine Llc |
Benzoxazole kinase inhibitors and methods of use
|
MY157017A
(en)
*
|
2009-01-12 |
2016-04-15 |
Pfizer Ltd |
Sulfonamide derivatives
|
CA2750519C
(fr)
|
2009-02-05 |
2018-09-25 |
Immunogen, Inc. |
Derives de benzodiazepine
|
AU2010210986A1
(en)
|
2009-02-09 |
2011-08-25 |
Supergen, Inc. |
Pyrrolopyrimidinyl Axl kinase inhibitors
|
WO2010099139A2
(fr)
|
2009-02-25 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Thérapie anti-cancer combinée
|
EP2400990A2
(fr)
|
2009-02-26 |
2012-01-04 |
OSI Pharmaceuticals, LLC |
Procédés in situ pour surveiller l'état emt de cellules tumorales in vivo
|
JP2012519282A
(ja)
|
2009-02-27 |
2012-08-23 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
間葉様腫瘍細胞またはその生成を阻害する薬剤を同定するための方法
|
EP2401614A1
(fr)
|
2009-02-27 |
2012-01-04 |
OSI Pharmaceuticals, LLC |
Méthodes d'identification d'agents qui inhibent les cellules cancéreuses mésenchymateuses ou leur formation
|
TW201035088A
(en)
|
2009-02-27 |
2010-10-01 |
Supergen Inc |
Cyclopentathiophene/cyclohexathiophene DNA methyltransferase inhibitors
|
WO2010099138A2
(fr)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Procédés pour l'identification d'agents qui inhibent les cellules tumorales de type mésenchymateuses ou leur formation
|
JP5844727B2
(ja)
|
2009-03-27 |
2016-01-20 |
アルデア バイオサイエンシズ,インコーポレイティド |
Mek阻害剤としてのジヒドロピリジンスルホンアミド及びジヒドロピリジンスルファミド
|
EP2427195B1
(fr)
|
2009-05-07 |
2019-05-01 |
Intellikine, LLC |
Composés hétérocycliques et leurs utilisations
|
JP2013500991A
(ja)
|
2009-07-31 |
2013-01-10 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
mTOR阻害剤および血管新生阻害剤併用療法
|
US9085560B2
(en)
|
2009-08-17 |
2015-07-21 |
Intellikine, Inc. |
Heterocyclic compounds and uses thereof
|
JP2013503846A
(ja)
|
2009-09-01 |
2013-02-04 |
ファイザー・インク |
ベンズイミダゾール誘導体
|
BR112012008599A2
(pt)
|
2009-10-13 |
2019-09-24 |
Allostem Therapeutics Llc |
composto da formula (i), composto da fórmula (ia), composto da fórmula (ic), composto da fórmula (ii), composto da fórmula (iia), composto, método para tratamento de um transtorno hiperproliferativo em um mamífero, que inclui um humano, método para tratamento de uma doença, condição ou transtorno inflamatório em um mamífero, que inclui um humano, método para tratamento de um transtorno ou condição que é modulada pela cascata de meik em um mamífero, que inclui um himano, método para tratar ou prevenir câncer, composição farmacêutica e método para inibir uma enzima mek
|
WO2011049625A1
(fr)
|
2009-10-20 |
2011-04-28 |
Mansour Samadpour |
Procédé de criblage d'aflatoxine dans des produits
|
EA036876B1
(ru)
|
2009-11-05 |
2020-12-30 |
Ризен Фармасьютикалз С.А. |
Ингибиторы pi3k киназы
|
WO2011100403A1
(fr)
|
2010-02-10 |
2011-08-18 |
Immunogen, Inc |
Anticorps anti-cd20 et utilisations de ceux-ci
|
CA2787881C
(fr)
|
2010-02-12 |
2019-01-08 |
Pfizer Inc. |
Sels et polymorphes de la 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6h-azepino[5,4,3-cd]indol-6-one
|
AU2011223655A1
(en)
|
2010-03-03 |
2012-06-28 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
|
AU2011223643A1
(en)
|
2010-03-03 |
2012-06-28 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
|
NZ703111A
(en)
|
2010-05-17 |
2016-07-29 |
Incozen Therapeutics Pvt Ltd |
Novel 3,5-disubstitued-3h-imidazo[4,5-b]pyridine and 3,5- disubstitued -3h-[1,2,3]triazolo[4,5-b] pyridine compounds as modulators of protein kinases
|
AU2011255218B2
(en)
|
2010-05-21 |
2015-03-12 |
Infinity Pharmaceuticals, Inc. |
Chemical compounds, compositions and methods for kinase modulation
|
AU2011268356B2
(en)
|
2010-06-16 |
2013-09-19 |
University Of Pittsburgh-Of The Commonwealth System Of Higher Education |
Antibodies to endoplasmin and their use
|
WO2012004706A2
(fr)
|
2010-07-09 |
2012-01-12 |
Pfizer Limited |
Composés chimiques
|
JP5802756B2
(ja)
|
2010-10-20 |
2015-11-04 |
ファイザー・インク |
スムーズンド受容体モジュレーターとしてのピリジン−2−誘導体
|
WO2012064973A2
(fr)
|
2010-11-10 |
2012-05-18 |
Infinity Pharmaceuticals, Inc. |
Composés hétérocycliques et utilisations de ceux-ci
|
KR20180080358A
(ko)
|
2011-01-10 |
2018-07-11 |
인피니티 파마슈티칼스, 인코포레이티드 |
이소퀴놀린온 및 이의 고체 형태의 제조 방법
|
AU2012212075A1
(en)
|
2011-02-02 |
2013-07-18 |
Amgen Inc. |
Methods and compositons relating to inhibition of IGF-1R
|
CN113896731A
(zh)
|
2011-02-15 |
2022-01-07 |
伊缪诺金公司 |
细胞毒性苯并二氮杂䓬衍生物
|
US20120214830A1
(en)
|
2011-02-22 |
2012-08-23 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors in hepatocellular carcinoma
|
JP5808826B2
(ja)
|
2011-02-23 |
2015-11-10 |
インテリカイン, エルエルシー |
複素環化合物およびその使用
|
WO2012142164A1
(fr)
|
2011-04-12 |
2012-10-18 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Anticorps monoclonaux humains qui se lient aux facteurs de croissance insulinomimétique (igf) de type i et ii
|
CA2830972C
(fr)
|
2011-04-19 |
2018-11-20 |
Pfizer Inc. |
Combinaisons d'anticorps anti-4-1bb et d'anticorps induisant une cytotoxicite a mediation cellulaire dependante d'un anticorps (adcc) pour le traitement du cancer
|
WO2012149014A1
(fr)
|
2011-04-25 |
2012-11-01 |
OSI Pharmaceuticals, LLC |
Utilisation de signatures de gènes de tem dans la découverte de médicaments contre le cancer, diagnostics et traitement du cancer
|
CA2833935C
(fr)
|
2011-05-04 |
2020-09-15 |
Dhanapalan Nagarathnam |
Nouveaux composes en tant que modulateurs de proteines kinases
|
WO2012174158A2
(fr)
|
2011-06-14 |
2012-12-20 |
Hale Biopharma Ventures, Llc |
Administration de benzodiazépine
|
AR088218A1
(es)
|
2011-07-19 |
2014-05-21 |
Infinity Pharmaceuticals Inc |
Compuestos heterociclicos utiles como inhibidores de pi3k
|
CN103930422A
(zh)
|
2011-07-19 |
2014-07-16 |
无限药品股份有限公司 |
杂环化合物及其用途
|
WO2013013188A1
(fr)
|
2011-07-21 |
2013-01-24 |
Tolero Pharmaceuticals, Inc. |
Inhibiteurs de protéine kinase hétérocycliques
|
AU2012302197B2
(en)
|
2011-08-29 |
2016-01-07 |
Infinity Pharmaceuticals Inc. |
Heterocyclic compounds and uses thereof
|
CN103814030A
(zh)
|
2011-09-22 |
2014-05-21 |
辉瑞大药厂 |
吡咯并嘧啶及嘌呤衍生物
|
US9630979B2
(en)
|
2011-09-29 |
2017-04-25 |
Infinity Pharmaceuticals, Inc. |
Inhibitors of monoacylglycerol lipase and methods of their use
|
AU2011378675B2
(en)
|
2011-10-04 |
2017-10-05 |
Epsilogen Ltd |
IgE anti -HMW-MAA antibody
|
AU2012335247A1
(en)
|
2011-11-08 |
2014-05-29 |
Pfizer Inc. |
Methods of treating inflammatory disorders using anti-M-CSF antibodies
|
EP3345624A1
(fr)
|
2012-02-22 |
2018-07-11 |
The Regents Of The University Of Colorado |
Dérivés de bouvardin et leurs utilisations thérapeutiques
|
US9452215B2
(en)
|
2012-02-22 |
2016-09-27 |
The Regents Of The University Of Colorado |
Bourvadin derivatives and therapeutic uses thereof
|
WO2013144737A2
(fr)
|
2012-03-30 |
2013-10-03 |
Rhizen Pharmaceuticals Sa |
Nouveaux composés 3,5-disubstitués-3h-imidazo[4,5-b]pyridines et 3,5-disubstitués-3h-[1,2,3]triazolo[4,5-b]pyridines en tant que modulateurs des protéines kinases c-met
|
WO2013152252A1
(fr)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Polythérapie antinéoplasique
|
US8940742B2
(en)
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
AU2013270684B2
(en)
|
2012-06-08 |
2018-04-19 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
DK2863955T3
(en)
|
2012-06-26 |
2017-01-23 |
Sutro Biopharma Inc |
MODIFIED FC PROTEINS, INCLUDING LOCATION-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES THEREOF, METHODS OF PRODUCING ITS AND PROCEDURES FOR USE THEREOF
|
EP2887965A1
(fr)
|
2012-08-22 |
2015-07-01 |
ImmunoGen, Inc. |
Dérivés de benzodiazépine cytotoxique
|
EP3584255B1
(fr)
|
2012-08-31 |
2022-02-16 |
Sutro Biopharma, Inc. |
Acides aminés modifiés comprenant un groupe azido
|
ES2644758T3
(es)
|
2012-10-16 |
2017-11-30 |
Tolero Pharmaceuticals, Inc. |
Moduladores de PKM2 y métodos para su uso
|
BR112015010035A2
(pt)
|
2012-11-01 |
2017-07-11 |
Infinity Pharmaceuticals Inc |
tratamento de câncer usando moduladores de isoformas quinase pi3
|
EP2961435B1
(fr)
|
2013-02-28 |
2019-05-01 |
ImmunoGen, Inc. |
Conjugués comprenant des agents de liaison cellulaire (cba) et des agents cytotoxiques
|
EP3566750A3
(fr)
|
2013-02-28 |
2020-04-08 |
ImmunoGen, Inc. |
Conjugués comprenant des agents de liaison cellulaire et des agents cytotoxiques
|
KR102334260B1
(ko)
|
2013-03-14 |
2021-12-02 |
스미토모 다이니폰 파마 온콜로지, 인크. |
Jak2 및 alk2 억제제 및 이들의 사용 방법
|
CN105246482A
(zh)
|
2013-03-15 |
2016-01-13 |
因特利凯有限责任公司 |
激酶抑制剂的组合及其用途
|
EP3401314B1
(fr)
|
2013-03-15 |
2023-11-08 |
Araxes Pharma LLC |
Inhibiteurs covalents de kras g12c
|
WO2014143659A1
(fr)
|
2013-03-15 |
2014-09-18 |
Araxes Pharma Llc |
Inhibiteurs covalents irréversibles de la gtpase k-ras g12c
|
NZ629037A
(en)
|
2013-03-15 |
2017-04-28 |
Infinity Pharmaceuticals Inc |
Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
|
US9227978B2
(en)
|
2013-03-15 |
2016-01-05 |
Araxes Pharma Llc |
Covalent inhibitors of Kras G12C
|
KR20160013204A
(ko)
|
2013-05-30 |
2016-02-03 |
인피니티 파마슈티칼스, 인코포레이티드 |
Pi3 키나아제 동형단백질 조절제를 사용하는 암의 치료
|
WO2014194030A2
(fr)
|
2013-05-31 |
2014-12-04 |
Immunogen, Inc. |
Conjugués comprenant des agents de liaison cellulaire et des agents cytotoxiques
|
ES2865473T3
(es)
|
2013-07-10 |
2021-10-15 |
Sutro Biopharma Inc |
Anticuerpos que comprenden múltiples residuos de aminoácidos no naturales sitio-específicos, métodos para su preparación y métodos de uso
|
EA032196B1
(ru)
|
2013-10-03 |
2019-04-30 |
Кура Онколоджи, Инк. |
Ингибиторы erk и способы применения
|
NZ718430A
(en)
|
2013-10-04 |
2021-12-24 |
Infinity Pharmaceuticals Inc |
Heterocyclic compounds and uses thereof
|
US9751888B2
(en)
|
2013-10-04 |
2017-09-05 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
CA2926328C
(fr)
|
2013-10-10 |
2022-11-29 |
Araxes Pharma Llc |
Quinazoline substituee et derives de quinoline et compositions pharmaceutiques connexes utiles comme inhibiteurs de kras g12c
|
TWI659021B
(zh)
|
2013-10-10 |
2019-05-11 |
亞瑞克西斯製藥公司 |
Kras g12c之抑制劑
|
US9840493B2
(en)
|
2013-10-11 |
2017-12-12 |
Sutro Biopharma, Inc. |
Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use
|
WO2015061204A1
(fr)
|
2013-10-21 |
2015-04-30 |
Infinity Pharmaceuticals, Inc. |
Composés hétérocycliques et leurs utilisations
|
UA115388C2
(uk)
|
2013-11-21 |
2017-10-25 |
Пфайзер Інк. |
2,6-заміщені пуринові похідні та їх застосування в лікуванні проліферативних захворювань
|
WO2015155624A1
(fr)
|
2014-04-10 |
2015-10-15 |
Pfizer Inc. |
Dérivés de dihydropyrrolopyrimidine
|
WO2015168079A1
(fr)
|
2014-04-29 |
2015-11-05 |
Infinity Pharmaceuticals, Inc. |
Dérivés de pyrimidine ou de pyridine utiles en tant qu'inhibiteurs de pi3k
|
AP2016009530A0
(en)
|
2014-04-30 |
2016-10-31 |
Pfizer |
Cycloalkyl-linked diheterocycle derivatives
|
CR20170011A
(es)
|
2014-06-19 |
2017-04-04 |
Ariad Pharma Inc |
Compuestos de heteroarilo para la inhibición de cinasa
|
WO2016001789A1
(fr)
|
2014-06-30 |
2016-01-07 |
Pfizer Inc. |
Dérivés de pyrimidine en tant qu'inhibiteurs de pi3k destinés à être utilisés dans le traitement du cancer
|
US10934360B2
(en)
|
2014-07-31 |
2021-03-02 |
The Hong Kong University Of Science And Technology |
Human monoclonal antibodies against EPHA4 and their use
|
JO3556B1
(ar)
|
2014-09-18 |
2020-07-05 |
Araxes Pharma Llc |
علاجات مدمجة لمعالجة السرطان
|
US10011600B2
(en)
|
2014-09-25 |
2018-07-03 |
Araxes Pharma Llc |
Methods and compositions for inhibition of Ras
|
WO2016049524A1
(fr)
|
2014-09-25 |
2016-03-31 |
Araxes Pharma Llc |
Inhibiteurs de protéines mutantes kras g12c
|
JP6621477B2
(ja)
|
2014-12-18 |
2019-12-18 |
ファイザー・インク |
ピリミジンおよびトリアジン誘導体ならびにaxl阻害薬としてのそれらの使用
|
ES2898765T3
(es)
|
2015-04-10 |
2022-03-08 |
Araxes Pharma Llc |
Compuestos de quinazolina sustituidos y métodos de uso de los mismos
|
MX2017013275A
(es)
|
2015-04-15 |
2018-01-26 |
Araxes Pharma Llc |
Inhibidores triciclicos fusionados de kras y metodos de uso de los mismos.
|
CN107995863A
(zh)
|
2015-04-20 |
2018-05-04 |
特雷罗药物股份有限公司 |
通过线粒体分析预测对阿伏西地的应答
|
MX2017013956A
(es)
|
2015-05-01 |
2018-09-05 |
Cocrystal Pharma Inc |
Analogos de nucleosidos para el tratamiento de la familia de virus flaviviridae y cancer.
|
BR112017024933A8
(pt)
|
2015-05-18 |
2022-10-18 |
Tolero Pharmaceuticals Inc |
Alvocidib produce com a bioavailabilidade aumentada
|
TWI703150B
(zh)
|
2015-06-04 |
2020-09-01 |
美商庫拉腫瘤技術股份有限公司 |
用於抑制menin及mll蛋白之交互作用的方法及組合物
|
WO2017009751A1
(fr)
|
2015-07-15 |
2017-01-19 |
Pfizer Inc. |
Dérivés de pyrimidine
|
US10144724B2
(en)
|
2015-07-22 |
2018-12-04 |
Araxes Pharma Llc |
Substituted quinazoline compounds and methods of use thereof
|
US10568887B2
(en)
|
2015-08-03 |
2020-02-25 |
Tolero Pharmaceuticals, Inc. |
Combination therapies for treatment of cancer
|
EP3356339A1
(fr)
|
2015-09-28 |
2018-08-08 |
Araxes Pharma LLC |
Inhibiteurs de protéines mutantes kras g12c
|
WO2017058728A1
(fr)
|
2015-09-28 |
2017-04-06 |
Araxes Pharma Llc |
Inhibiteurs de protéines kras portant la mutation g12c
|
EP3356351A1
(fr)
|
2015-09-28 |
2018-08-08 |
Araxes Pharma LLC |
Inhibiteurs de protéines kras portant la mutation g12c
|
EP3356359B1
(fr)
|
2015-09-28 |
2021-10-20 |
Araxes Pharma LLC |
Inhibiteurs de protéines kras portant la mutation g12c
|
EP3356354A1
(fr)
|
2015-09-28 |
2018-08-08 |
Araxes Pharma LLC |
Inhibiteurs de protéines kras portant la mutation g12c
|
WO2017058807A1
(fr)
|
2015-09-28 |
2017-04-06 |
Araxes Pharma Llc |
Inhibiteurs de protéines kras portant la mutation g12c
|
EP3356349A1
(fr)
|
2015-09-28 |
2018-08-08 |
Araxes Pharma LLC |
Inhibiteurs de protéines mutantes kras g12c
|
EP3364977A4
(fr)
|
2015-10-19 |
2019-09-04 |
Araxes Pharma LLC |
Méthode de criblage d'inhibiteurs de ras
|
TW201726656A
(zh)
|
2015-11-16 |
2017-08-01 |
亞瑞克西斯製藥公司 |
包含經取代雜環基團之2-經取代喹唑啉化合物及其使用方法
|
JP6877429B2
(ja)
|
2015-12-03 |
2021-05-26 |
アジオス ファーマシューティカルズ, インコーポレイテッド |
Mtapヌル癌を処置するためのmat2a阻害剤
|
US9988357B2
(en)
|
2015-12-09 |
2018-06-05 |
Araxes Pharma Llc |
Methods for preparation of quinazoline derivatives
|
US11708413B2
(en)
|
2016-01-27 |
2023-07-25 |
Sutro Biopharma, Inc. |
Anti-CD74 antibody conjugates, compositions comprising anti-CD74 antibody conjugates and methods of using anti-CD74 antibody conjugates
|
WO2017161028A1
(fr)
|
2016-03-16 |
2017-09-21 |
Kura Oncology, Inc. |
Inhibiteurs substitués de ménine-mll et méthodes d'utilisation
|
KR102419524B1
(ko)
|
2016-03-16 |
2022-07-08 |
쿠라 온콜로지, 인크. |
메닌-mll의 가교된 이환식 억제제 및 사용 방법
|
US10822312B2
(en)
|
2016-03-30 |
2020-11-03 |
Araxes Pharma Llc |
Substituted quinazoline compounds and methods of use
|
CN109414596B
(zh)
|
2016-05-12 |
2023-09-29 |
密歇根大学董事会 |
Ash1l抑制剂和用其进行治疗的方法
|
US11118233B2
(en)
|
2016-05-18 |
2021-09-14 |
The University Of Chicago |
BTK mutation and ibrutinib resistance
|
US10919914B2
(en)
|
2016-06-08 |
2021-02-16 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
US10646488B2
(en)
|
2016-07-13 |
2020-05-12 |
Araxes Pharma Llc |
Conjugates of cereblon binding compounds and G12C mutant KRAS, HRAS or NRAS protein modulating compounds and methods of use thereof
|
US10870694B2
(en)
|
2016-09-02 |
2020-12-22 |
Dana Farber Cancer Institute, Inc. |
Composition and methods of treating B cell disorders
|
WO2018064510A1
(fr)
|
2016-09-29 |
2018-04-05 |
Araxes Pharma Llc |
Inhibiteurs de protéines mutantes kras g12c
|
CN110312711A
(zh)
|
2016-10-07 |
2019-10-08 |
亚瑞克西斯制药公司 |
作为ras抑制剂的杂环化合物及其使用方法
|
US11279694B2
(en)
|
2016-11-18 |
2022-03-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
WO2018098352A2
(fr)
|
2016-11-22 |
2018-05-31 |
Jun Oishi |
Ciblage d'expression du point de contrôle immunitaire induit par kras
|
CA3047557A1
(fr)
|
2016-12-19 |
2018-06-28 |
Tolero Pharmaceuticals, Inc. |
Peptides de profilage et procedes de profilage de sensibilite
|
KR20230150408A
(ko)
|
2016-12-22 |
2023-10-30 |
암젠 인크 |
폐암, 췌장암 또는 대장암을 치료하기 위한 kras g12c 억제제로서의 벤즈이소티아졸, 이소티아졸로[3,4-b]피리딘, 퀴나졸린, 프탈라진, 피리도[2,3-d]피리다진 및 피리도[2,3-d]피리미딘 유도체
|
JP2020505395A
(ja)
|
2017-01-26 |
2020-02-20 |
アラクセス ファーマ エルエルシー |
縮合n−複素環式化合物およびその使用方法
|
EP3573971A1
(fr)
|
2017-01-26 |
2019-12-04 |
Araxes Pharma LLC |
Dérivés de 1-(3-(6-(3-hydroxynaphtalen-1-yl)benzofuran-2-yl)azétidin-1yl)prop-2-en-1-one et composés similaires utilisés en tant que modulateurs de kras g12c pour le traitement du cancer
|
US11136308B2
(en)
|
2017-01-26 |
2021-10-05 |
Araxes Pharma Llc |
Substituted quinazoline and quinazolinone compounds and methods of use thereof
|
WO2018140512A1
(fr)
|
2017-01-26 |
2018-08-02 |
Araxes Pharma Llc |
Composés benzohétéroaromatiques bicycliques fusionnés et leurs procédés d'utilisation
|
EP3573967A1
(fr)
|
2017-01-26 |
2019-12-04 |
Araxes Pharma LLC |
Composés hétéro-hétéro-bicycliques fusionnés et leurs procédés d'utilisation
|
US11267885B2
(en)
|
2017-01-26 |
2022-03-08 |
Zlip Holding Limited |
CD47 antigen binding unit and uses thereof
|
EP3573964A1
(fr)
|
2017-01-26 |
2019-12-04 |
Araxes Pharma LLC |
Composés à base de benzothiophène et de benzothiazole et leurs procédés d'utilisation
|
CN110691779B
(zh)
|
2017-03-24 |
2023-10-10 |
库拉肿瘤学公司 |
治疗血液系统恶性肿瘤和尤因肉瘤的方法
|
JOP20190272A1
(ar)
|
2017-05-22 |
2019-11-21 |
Amgen Inc |
مثبطات kras g12c وطرق لاستخدامها
|
WO2018218071A1
(fr)
|
2017-05-25 |
2018-11-29 |
Araxes Pharma Llc |
Composés et leurs procédés d'utilisation pour le traitement du cancer
|
AU2018271990A1
(en)
|
2017-05-25 |
2019-12-12 |
Araxes Pharma Llc |
Covalent inhibitors of KRAS
|
US11639346B2
(en)
|
2017-05-25 |
2023-05-02 |
Araxes Pharma Llc |
Quinazoline derivatives as modulators of mutant KRAS, HRAS or NRAS
|
WO2018226976A1
(fr)
|
2017-06-08 |
2018-12-13 |
Kura Oncology, Inc. |
Procédés et compositions d'inhibition de l'interaction de la ménine avec les protéines mll
|
WO2019023316A1
(fr)
|
2017-07-26 |
2019-01-31 |
Sutro Biopharma, Inc. |
Méthodes d'utilisation d'anticorps anti-cd74 et de conjugués d'anticorps dans le traitement d'un lymphome à cellules t
|
SG11202001499WA
(en)
|
2017-09-08 |
2020-03-30 |
Amgen Inc |
Inhibitors of kras g12c and methods of using the same
|
JP7196160B2
(ja)
|
2017-09-12 |
2022-12-26 |
スミトモ ファーマ オンコロジー, インコーポレイテッド |
Mcl-1阻害剤アルボシジブを用いた、bcl-2阻害剤に対して非感受性である癌の治療レジメン
|
BR112020005212A2
(pt)
|
2017-09-18 |
2020-09-15 |
Sutro Biopharma, Inc. |
conjugado de anticorpo, kit, composição farmacêutica, e, métodos de tratamento ou prevenção e de diagnóstico de uma doença ou condição.
|
EP3684361A4
(fr)
|
2017-09-20 |
2021-09-08 |
Kura Oncology, Inc. |
Inhibiteurs substitués de ménine-mll et méthodes d'utilisation
|
WO2019075367A1
(fr)
|
2017-10-13 |
2019-04-18 |
Tolero Pharmaceuticals, Inc. |
Activateurs de pkm2 en combinaison avec des espèces réactives de l'oxygène pour le traitement du cancer
|
US10632209B2
(en)
|
2017-11-10 |
2020-04-28 |
The Regents Of The University Of Michigan |
ASH1L inhibitors and methods of treatment therewith
|
EP3720439A4
(fr)
|
2017-12-07 |
2021-09-08 |
The Regents Of The University Of Michigan |
Inhibiteurs de la famille nsd et méthodes de traitement comprenant ces derniers
|
KR20210003780A
(ko)
|
2018-04-05 |
2021-01-12 |
스미토모 다이니폰 파마 온콜로지, 인크. |
Axl 키나제 억제제 및 그의 용도
|
EP3788038B1
(fr)
|
2018-05-04 |
2023-10-11 |
Amgen Inc. |
Inhibiteurs de kras g12c et leurs procédés d'utilisation
|
US11045484B2
(en)
|
2018-05-04 |
2021-06-29 |
Amgen Inc. |
KRAS G12C inhibitors and methods of using the same
|
WO2019217691A1
(fr)
|
2018-05-10 |
2019-11-14 |
Amgen Inc. |
Inhibiteurs de kras g12c pour le traitement du cancer
|
CA3098885A1
(fr)
|
2018-06-01 |
2019-12-05 |
Amgen Inc. |
Inhibiteurs de kras g12c et leurs procedes d'utilisation
|
WO2019236957A1
(fr)
|
2018-06-07 |
2019-12-12 |
The Regents Of The University Of Michigan |
Inhibiteurs de prc1 et méthodes de traitement comprenant ces derniers
|
EP4268898A3
(fr)
|
2018-06-11 |
2024-01-17 |
Amgen Inc. |
Inhibiteurs de kras g12c pour le traitement du cancer
|
US11285156B2
(en)
|
2018-06-12 |
2022-03-29 |
Amgen Inc. |
Substituted piperazines as KRAS G12C inhibitors
|
CN112512597A
(zh)
|
2018-07-26 |
2021-03-16 |
大日本住友制药肿瘤公司 |
用于治疗与acvr1表达异常相关的疾病的方法以及用于此的acvr1抑制剂
|
JP2021532157A
(ja)
|
2018-08-01 |
2021-11-25 |
アラクセス ファーマ エルエルシー |
がんを処置するための複素環式スピロ化合物およびその使用方法
|
EP3852811A1
(fr)
|
2018-09-17 |
2021-07-28 |
Sutro Biopharma, Inc. |
Polythérapies avec des conjugués d'anticorps anti-récepteur du folate
|
WO2020086739A1
(fr)
|
2018-10-24 |
2020-04-30 |
Araxes Pharma Llc |
Dérivés de 2-(2-acryloyl-2,6-diazaspiro[3.4]octan-6-yl)-6-(1h-indazol-4-yl)-benzonitrile et composés apparentés en tant qu'inhibiteurs de protéine kras g12c mutante pour l'inhibition de métastase tumorale
|
JP7516029B2
(ja)
|
2018-11-16 |
2024-07-16 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤化合物の重要な中間体の改良合成法
|
JP7377679B2
(ja)
|
2018-11-19 |
2023-11-10 |
アムジエン・インコーポレーテツド |
がん治療のためのkrasg12c阻害剤及び1種以上の薬学的に活性な追加の薬剤を含む併用療法
|
EP3883565A1
(fr)
|
2018-11-19 |
2021-09-29 |
Amgen Inc. |
Inhibiteurs de kras g12c et leurs procédés d'utilisation
|
JP2022509830A
(ja)
|
2018-11-29 |
2022-01-24 |
アラクセス ファーマ エルエルシー |
がんを処置するための化合物およびその使用方法
|
CN113490499A
(zh)
|
2018-12-04 |
2021-10-08 |
大日本住友制药肿瘤公司 |
用作治疗癌症的活性剂的cdk9抑制剂及其多晶型物
|
US20220002311A1
(en)
|
2018-12-20 |
2022-01-06 |
Amgen Inc. |
Kif18a inhibitors
|
US20220056015A1
(en)
|
2018-12-20 |
2022-02-24 |
Amgen Inc. |
Kif18a inhibitors
|
AU2019403488A1
(en)
|
2018-12-20 |
2021-06-24 |
Amgen Inc. |
KIF18A inhibitors
|
EA202191730A1
(ru)
|
2018-12-20 |
2021-08-24 |
Эмджен Инк. |
Ингибиторы kif18a
|
US11471456B2
(en)
|
2019-02-12 |
2022-10-18 |
Sumitomo Pharma Oncology, Inc. |
Formulations comprising heterocyclic protein kinase inhibitors
|
CA3130080A1
(fr)
|
2019-03-01 |
2020-09-10 |
Revolution Medicines, Inc. |
Composes heteroaryle bicycliques et leurs utilisations
|
JP2022522778A
(ja)
|
2019-03-01 |
2022-04-20 |
レボリューション メディシンズ インコーポレイテッド |
二環式ヘテロシクリル化合物及びその使用
|
US11793802B2
(en)
|
2019-03-20 |
2023-10-24 |
Sumitomo Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (AML) with venetoclax failure
|
WO2020198077A1
(fr)
|
2019-03-22 |
2020-10-01 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Compositions comprenant des modulateurs de pkm2 et méthodes de traitement les utilisant
|
US20220362394A1
(en)
|
2019-05-03 |
2022-11-17 |
Sutro Biopharma, Inc. |
Anti-bcma antibody conjugates
|
EP3738593A1
(fr)
|
2019-05-14 |
2020-11-18 |
Amgen, Inc |
Dosage d'inhibiteur de kras pour le traitement de cancers
|
CR20210665A
(es)
|
2019-05-21 |
2022-01-25 |
Amgen Inc |
Formas en estado sólido
|
EP3994132A1
(fr)
|
2019-07-03 |
2022-05-11 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Inhibiteurs de tyrosine kinase non récepteur 1 (tnk1) et leurs utilisations
|
CN114302880A
(zh)
|
2019-08-02 |
2022-04-08 |
美国安进公司 |
Kif18a抑制剂
|
MX2022001181A
(es)
|
2019-08-02 |
2022-02-22 |
Amgen Inc |
Inhibidores de kif18a.
|
US20220372018A1
(en)
|
2019-08-02 |
2022-11-24 |
Amgen Inc. |
Kif18a inhibitors
|
JP2022542319A
(ja)
|
2019-08-02 |
2022-09-30 |
アムジエン・インコーポレーテツド |
Kif18a阻害剤
|
EP4031542A4
(fr)
|
2019-09-18 |
2023-10-25 |
Merck Sharp & Dohme LLC |
Inhibiteurs à petites molécules de mutant de kras g12c
|
WO2021067215A1
(fr)
|
2019-09-30 |
2021-04-08 |
Agios Pharmaceuticals, Inc. |
Composés de pipéridine utilisés en tant qu'inhibiteurs de ménine
|
CA3155857A1
(fr)
|
2019-10-24 |
2021-04-29 |
Amgen Inc. |
Derives de pyridopyrimidine utiles en tant qu'inhibiteurs de kras g12c et de kras g12d dans le traitement du cancer
|
WO2021086833A1
(fr)
|
2019-10-28 |
2021-05-06 |
Merck Sharp & Dohme Corp. |
Inhibiteurs à petites molécules de mutant de kras g12c
|
JP2023515235A
(ja)
|
2019-10-31 |
2023-04-12 |
大鵬薬品工業株式会社 |
4-アミノブタ-2-エンアミド誘導体及びその塩
|
EP4054719A1
(fr)
|
2019-11-04 |
2022-09-14 |
Revolution Medicines, Inc. |
Inhibiteurs de ras
|
TW202132314A
(zh)
|
2019-11-04 |
2021-09-01 |
美商銳新醫藥公司 |
Ras抑制劑
|
JP2022553857A
(ja)
|
2019-11-04 |
2022-12-26 |
レボリューション メディシンズ インコーポレイテッド |
Ras阻害剤
|
AU2020380315A1
(en)
|
2019-11-08 |
2022-05-26 |
Revolution Medicines, Inc. |
Bicyclic heteroaryl compounds and uses thereof
|
JP2023501522A
(ja)
|
2019-11-14 |
2023-01-18 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤化合物の改良合成法
|
AU2020381492A1
(en)
|
2019-11-14 |
2022-05-26 |
Amgen Inc. |
Improved synthesis of KRAS G12C inhibitor compound
|
CN114980976A
(zh)
|
2019-11-27 |
2022-08-30 |
锐新医药公司 |
共价ras抑制剂及其用途
|
WO2021106231A1
(fr)
|
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2021-06-03 |
Taiho Pharmaceutical Co., Ltd. |
Composé ayant une activité inhibitrice contre la mutation kras g12d
|
MX2022008305A
(es)
|
2020-01-07 |
2022-08-08 |
Revolution Medicines Inc |
Dosificacion de inhibidores de shp2 y metodos de tratamiento del cancer.
|
WO2021155006A1
(fr)
|
2020-01-31 |
2021-08-05 |
Les Laboratoires Servier Sas |
Inhibiteurs de kinases dépendantes des cyclines et leurs utilisations
|
EP4114852A1
(fr)
|
2020-03-03 |
2023-01-11 |
Sutro Biopharma, Inc. |
Anticorps comprenant des étiquettes de glutamine spécifiques à un site, leurs procédés de préparation et d'utilisation
|
TW202204334A
(zh)
|
2020-04-08 |
2022-02-01 |
美商阿吉歐斯製藥公司 |
Menin抑制劑及治療癌症之使用方法
|
WO2021204159A1
(fr)
|
2020-04-08 |
2021-10-14 |
Agios Pharmaceuticals, Inc. |
Inhibiteurs de ménine et procédés d'utilisation pour le traitement du cancer
|
WO2021215545A1
(fr)
|
2020-04-24 |
2021-10-28 |
Taiho Pharmaceutical Co., Ltd. |
Polythérapie anticancéreuse avec un inhibiteur de n-(1-acryloyl-azétidin-3-yl)-2-((1h-indazol-3-yl) amino) méthyl)-1 h-imidazole-5-carboxamide de kras-g12c
|
US20230174518A1
(en)
|
2020-04-24 |
2023-06-08 |
Taiho Pharmaceutical Co., Ltd. |
Kras g12d protein inhibitors
|
MX2022016355A
(es)
|
2020-06-18 |
2023-04-03 |
Revolution Medicines Inc |
Metodos para retardar, prevenir, y tratar la resistencia adquirida a inhibidores de ras.
|
US11858925B2
(en)
|
2020-07-10 |
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The Regents Of The University Of Michigan |
GAS41 inhibitors and methods of use thereof
|
EP4183395A4
(fr)
|
2020-07-15 |
2024-07-24 |
Taiho Pharmaceutical Co Ltd |
Combinaison contenant un composé pyrimidine destinée à être utilisée dans le traitement de tumeurs
|
EP4208261A1
(fr)
|
2020-09-03 |
2023-07-12 |
Revolution Medicines, Inc. |
Utilisation d'inhibiteurs de sos1 pour traiter des malignités à mutations de shp2
|
CN116457358A
(zh)
|
2020-09-15 |
2023-07-18 |
锐新医药公司 |
作为ras抑制剂以治疗癌症的吲哚衍生物
|
TW202237119A
(zh)
|
2020-12-10 |
2022-10-01 |
美商住友製藥腫瘤公司 |
Alk﹘5抑制劑和彼之用途
|
CN117396472A
(zh)
|
2020-12-22 |
2024-01-12 |
上海齐鲁锐格医药研发有限公司 |
Sos1抑制剂及其用途
|
TW202309022A
(zh)
|
2021-04-13 |
2023-03-01 |
美商努法倫特公司 |
用於治療具egfr突變之癌症之胺基取代雜環
|
AR125490A1
(es)
|
2021-04-30 |
2023-07-19 |
Celgene Corp |
Terapias de combinación que utilizan un anticuerpo anti-bcma conjugado a fármaco (adc) en combinación con un inhibidor de gamma secretasa (gsi)
|
EP4334324A1
(fr)
|
2021-05-05 |
2024-03-13 |
Revolution Medicines, Inc. |
Inhibiteurs de ras covalents et leurs utilisations
|
KR20240017811A
(ko)
|
2021-05-05 |
2024-02-08 |
레볼루션 메디슨즈, 인크. |
암의 치료를 위한 ras 억제제
|
AU2022270116A1
(en)
|
2021-05-05 |
2023-12-21 |
Revolution Medicines, Inc. |
Ras inhibitors
|
EP4347041A1
(fr)
|
2021-05-28 |
2024-04-10 |
Taiho Pharmaceutical Co., Ltd. |
Petites molécules inhibitrices de protéines mutées par kras
|
AR127308A1
(es)
|
2021-10-08 |
2024-01-10 |
Revolution Medicines Inc |
Inhibidores ras
|
WO2023056589A1
(fr)
|
2021-10-08 |
2023-04-13 |
Servier Pharmaceuticals Llc |
Inhibiteurs de ménine et procédés d'utilisation pour le traitement du cancer
|
WO2023114954A1
(fr)
|
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2023-06-22 |
Genzyme Corporation |
Composés pyrazolopyrazine utilisés comme inhibiteurs de la shp2
|
EP4227307A1
(fr)
|
2022-02-11 |
2023-08-16 |
Genzyme Corporation |
Composés pyrazolopyrazine en tant qu'inhibiteurs de shp2
|
WO2023172940A1
(fr)
|
2022-03-08 |
2023-09-14 |
Revolution Medicines, Inc. |
Méthodes de traitement du cancer du poumon réfractaire immunitaire
|
WO2023211812A1
(fr)
|
2022-04-25 |
2023-11-02 |
Nested Therapeutics, Inc. |
Dérivés hétérocycliques en tant qu'inhibiteurs de protéine kinase activée par mitogène (mek)
|
WO2023240263A1
(fr)
|
2022-06-10 |
2023-12-14 |
Revolution Medicines, Inc. |
Inhibiteurs de ras macrocycliques
|
TW202408589A
(zh)
|
2022-06-30 |
2024-03-01 |
美商舒卓生物製藥公司 |
抗ror1抗體及抗體結合物、包含抗ror1抗體或抗體結合物之組合物,及製造及使用抗ror1抗體及抗體結合物之方法
|
WO2024010925A2
(fr)
|
2022-07-08 |
2024-01-11 |
Nested Therapeutics, Inc. |
Inhibiteurs de protéine kinase activée par mitogène (mek)
|
WO2024081916A1
(fr)
|
2022-10-14 |
2024-04-18 |
Black Diamond Therapeutics, Inc. |
Méthodes de traitement de cancers à l'aide de dérivés d'isoquinoline ou de 6-aza-quinoléine
|
WO2024206858A1
(fr)
|
2023-03-30 |
2024-10-03 |
Revolution Medicines, Inc. |
Compositions pour induire une hydrolyse de ras gtp et leurs utilisations
|
WO2024211712A1
(fr)
|
2023-04-07 |
2024-10-10 |
Revolution Medicines, Inc. |
Composés macrocycliques condensés en tant qu'inhibiteurs de ras
|
WO2024211663A1
(fr)
|
2023-04-07 |
2024-10-10 |
Revolution Medicines, Inc. |
Composés macrocycliques condensés en tant qu'inhibiteurs de ras
|
US20240352036A1
(en)
|
2023-04-14 |
2024-10-24 |
Revolution Medicines, Inc. |
Crystalline forms of ras inhibitors, compositions containing the same, and methods of use thereof
|
US20240352038A1
(en)
|
2023-04-14 |
2024-10-24 |
Revolution Medicines, Inc. |
Crystalline forms of ras inhibitors, compositions containing the same, and methods of use thereof
|
WO2024226579A1
(fr)
|
2023-04-24 |
2024-10-31 |
Nested Therapeutics, Inc. |
Dérivé hétérocyclique utilisé comme inhibiteur de protéine kinase activée par les mitogènes (mek)
|