DZ2407A1 - Dérivés de sulfonylurée procédé pour leur préparation et compositions pharmaceutiques les contenant - Google Patents

Dérivés de sulfonylurée procédé pour leur préparation et compositions pharmaceutiques les contenant

Info

Publication number: DZ2407A1
Authority: DZ; Algeria
Prior art keywords: preparation; pharmaceutical compositions; compositions containing; sulfonylurea derivatives; derivatives process
Prior art date: 1997-01-29

Application number

DZ980017A

Other languages

English (en)

French (fr)

Inventor

Mark Anthony Dombroski

James Frederick Eggler

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-01-29

Filing date

1998-01-27

Publication date

2003-01-04

1998-01-27 Application filed by Pfizer filed Critical Pfizer

2003-01-04 Application granted granted Critical

2003-01-04 Publication of DZ2407A1 publication Critical patent/DZ2407A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/64—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
- C07C311/60—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/14—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
- C07C323/67—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfonamide groups, bound to the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Physical Education & Sports Medicine (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Orthopedic Medicine & Surgery (AREA)
Diabetes (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Immunology (AREA)
Hospice & Palliative Care (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Obesity (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

DZ980017A 1997-01-29 1998-01-27 Dérivés de sulfonylurée procédé pour leur préparation et compositions pharmaceutiques les contenant DZ2407A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US3697997P	1997-01-29	1997-01-29

Publications (1)

Publication Number	Publication Date
DZ2407A1 true DZ2407A1 (fr)	2003-01-04

Family

ID=21891776

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ980017A DZ2407A1 (fr)	1997-01-29	1998-01-27	Dérivés de sulfonylurée procédé pour leur préparation et compositions pharmaceutiques les contenant

Country Status (40)

Country	Link
US (2)	US6166064A (xx)
EP (1)	EP0964849B1 (xx)
JP (1)	JP3573757B2 (xx)
KR (1)	KR100324058B1 (xx)
CN (1)	CN1127479C (xx)
AP (1)	AP929A (xx)
AR (1)	AR011093A1 (xx)
AT (2)	ATE242208T1 (xx)
AU (1)	AU723895B2 (xx)
BG (1)	BG103597A (xx)
BR (1)	BR9714328A (xx)
CA (1)	CA2279186C (xx)
CO (1)	CO4920230A1 (xx)
CZ (1)	CZ293173B6 (xx)
DE (2)	DE69722663T2 (xx)
DK (2)	DK0964849T3 (xx)
DZ (1)	DZ2407A1 (xx)
EA (1)	EA001803B1 (xx)
ES (2)	ES2222426T3 (xx)
HR (1)	HRP980045B1 (xx)
HU (1)	HUP0000567A3 (xx)
ID (1)	ID22223A (xx)
IL (1)	IL130855A0 (xx)
IS (1)	IS5099A (xx)
MA (1)	MA26468A1 (xx)
NO (1)	NO313279B1 (xx)
NZ (1)	NZ336248A (xx)
OA (1)	OA11079A (xx)
PA (1)	PA8444701A1 (xx)
PE (1)	PE57898A1 (xx)
PL (1)	PL335052A1 (xx)
PT (2)	PT1270565E (xx)
SK (1)	SK283679B6 (xx)
TN (1)	TNSN98017A1 (xx)
TR (1)	TR199901816T2 (xx)
TW (1)	TW515788B (xx)
UY (1)	UY24861A1 (xx)
WO (1)	WO1998032733A1 (xx)
YU (1)	YU33799A (xx)
ZA (1)	ZA98685B (xx)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6022984A (en) *	1998-07-27	2000-02-08	Pfizer Inc.	Efficient synthesis of furan sulfonamide compounds useful in the synthesis of new IL-1 inhibitors
EP1526383A3 (en) *	1998-08-31	2005-11-16	Pfizer Products Inc.	Diarylsulfonylurea binding proteins
IT1303249B1 (it) *	1998-10-23	2000-11-06	Dompe Spa	Alcune n-(2-aril-propionil)-solfonammidi e preparazionifarmaceutiche che le contengono.
BR0014003A (pt) *	1999-09-14	2002-05-21	Pfizer Prod Inc	Tratamento de combinação com compostos de diaril sufonil uréia e il-1ra
US6808902B1 (en)	1999-11-12	2004-10-26	Amgen Inc.	Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
CA2369967A1 (en) *	2001-02-12	2002-08-12	Joseph Anthony Cornicelli	Methods of treating nuclear factor-kappa b mediated diseases and disorders
RS54274B1 (en)	2001-06-26	2016-02-29	Amgen Fremont Inc.	Opgl antibodies
MXPA04001785A (es)	2001-09-14	2004-07-08	Bayer Ag	Benzofurano y derivados de dihidrobenzofurano utiles como agonistas de beta-3 adrenoreceptores.
EP1487457A1 (en) *	2001-11-30	2004-12-22	Pfizer Products Inc.	Combination of an il-1/18 inhibitor with a tnf inhibitor for the treatment of inflammation
US20030131370A1 (en) *	2001-12-14	2003-07-10	Pfizer Inc.	Disruption of the glutathione S-transferase-Omega-1 gene
ATE349210T1 (de)	2002-07-09	2007-01-15	Boehringer Ingelheim Pharma	Pharazeutische zusammensetzungen aus anticholinergica und p38 kinase hemmern zur behandlung von erkrankungen der atemwege
CA2497884C (en)	2002-09-06	2013-10-22	Brian Varnum	Therapeutic human anti-il-1r1 monoclonal antibody
AU2003263560A1 (en) *	2002-10-03	2004-04-23	Pfizer Products Inc.	Use of gst-omega-2 as a therapeutic target
SG145745A1 (en)	2003-08-06	2008-09-29	Senomyx Inc	Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof
DE602005016937D1 (de) *	2004-03-23	2009-11-12	Dompe Pha R Ma Spa Res & Mfg	Pharmazeutische zusammensetzung
US20060045953A1 (en) *	2004-08-06	2006-03-02	Catherine Tachdjian	Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
US20060035893A1 (en)	2004-08-07	2006-02-16	Boehringer Ingelheim International Gmbh	Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
PE20060777A1 (es)	2004-12-24	2006-10-06	Boehringer Ingelheim Int	Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
MY158077A (en)	2005-02-04	2016-08-30	Senomyx Inc	Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers tastants and taste enhancers for comestible compositions
WO2006090921A1 (ja) *	2005-02-28	2006-08-31	Eisai R & D Management Co., Ltd.	スルホンアミド化合物のリンパ球活性化抑制作用
US7208526B2 (en) *	2005-05-20	2007-04-24	Hoffmann-La Roche Inc.	Styrylsulfonamides
TW200715993A (en)	2005-06-15	2007-05-01	Senomyx Inc	Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers
TWI674069B (zh)	2006-04-21	2019-10-11	美商賽諾米克斯公司	包含高度鮮味風味劑之可食用組合物及其製造方法
EP1992344A1 (en)	2007-05-18	2008-11-19	Institut Curie	P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation
US7973051B2 (en) *	2007-11-30	2011-07-05	Hoffman-La Roche Inc.	Aminothiazoles as FBPase inhibitors for diabetes
US20140206667A1 (en)	2012-11-14	2014-07-24	Michela Gallagher	Methods and compositions for treating schizophrenia
CA2957566C (en)	2014-08-12	2023-08-01	Daniel Paul Becker	Indoline sulfonamide inhibitors of dape and ndm-1 and use of the same
RS62164B1 (sr) *	2015-02-16	2021-08-31	Univ Queensland	Sulfoniluree i srodna jedinjenja i njihova upotreba
US10688077B2 (en) *	2015-02-26	2020-06-23	H. Lee Moffitt Cancer Center And Research Institute, Inc.	Inflammasome activation in myelodysplastic syndromes
FR3046933B1 (fr)	2016-01-25	2018-03-02	Galderma Research & Development	Inhibiteurs nlrp3 pour le traitement des pathologies cutanees inflammatoires
CA3014487A1 (en)	2016-02-16	2017-08-24	The Provost, Fellows, Foundation Scholars, And The Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin	Sulfonylureas and related compounds and use of same
ES2940611T3 (es) *	2016-04-18	2023-05-09	Novartis Ag	Compuestos y composiciones para el tratamiento de afecciones asociadas a la actividad de NLRP
WO2017184624A1 (en)	2016-04-18	2017-10-26	Ifm Therapeutics, Inc	Compounds and compositions for treating conditions associated with nlrp activity
EP3272739A1 (en) *	2016-07-20	2018-01-24	NodThera Limited	Sulfonyl urea derivatives and their use in the control of interleukin-1 activity
US20220267260A1 (en) *	2016-11-29	2022-08-25	Epizyme, Inc.	Compounds containing a sulfonic group as kat inhibitors
UA126675C2 (uk)	2017-01-23	2023-01-11	Дженентек, Інк.	Хімічні сполуки як інгібітори активності інтерлейкіну-1
CA3059458A1 (en) *	2017-05-24	2018-11-29	The University Of Queensland	Novel compounds and uses
EP3634951B8 (en)	2017-06-09	2024-08-21	Zydus Lifesciences Limited	Novel substituted sulfoximine compounds
EP3649112A1 (en)	2017-07-07	2020-05-13	Inflazome Limited	Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors
KR102669722B1 (ko)	2017-07-07	2024-05-29	인플라좀 리미티드	신규한 설폰아마이드 카복스아마이드 화합물
PL3658539T3 (pl)	2017-07-24	2024-07-01	Novartis Ag	Związki i kompozycje do leczenia stanów związanych z aktywnością nlrp
MX2020001778A (es)	2017-08-15	2020-03-24	Inflazome Ltd	Nuevos compuestos de sulfonamida carboxamida.
UY37847A (es)	2017-08-15	2019-03-29	Inflazome Ltd	Sulfonilureas y sulfoniltioureas útiles como inhibidores de nlrp3
US11926600B2 (en)	2017-08-15	2024-03-12	Inflazome Limited	Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors
US11518739B2 (en)	2017-08-15	2022-12-06	Inflazome Limited	Sulfonamide carboxamide compounds
US11542255B2 (en)	2017-08-15	2023-01-03	Inflazome Limited	Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors
WO2019043610A1 (en)	2017-08-31	2019-03-07	Cadila Healthcare Limited	NEW SUBSTITUTED SULFONYLUREA DERIVATIVES
US11623922B2 (en)	2017-10-03	2023-04-11	Inflazome Limited	Compounds
US11718631B2 (en)	2017-10-17	2023-08-08	Novartis Ag	Sulphonamides and compositions thereof for treating conditions associated with NLRP activity
EP3707137A1 (en)	2017-11-09	2020-09-16	Inflazome Limited	Novel sulfonamide carboxamide compounds
PE20210050A1 (es)	2017-11-09	2021-01-08	Inflazome Ltd	Nuevos compuestos de sulfonamida carboxamida
GB201721185D0 (en)	2017-12-18	2018-01-31	Nodthera Ltd	Sulphonyl urea derivatives
CN108299256B (zh) *	2018-01-09	2019-09-10	武汉大学	一类2,3,4-三羟基苯磺酰胺衍生物及其制备方法和应用
EP3759078A1 (en)	2018-03-02	2021-01-06	Inflazome Limited	Novel compounds
WO2019166629A1 (en)	2018-03-02	2019-09-06	Inflazome Limited	Novel compounds
WO2019166627A1 (en)	2018-03-02	2019-09-06	Inflazome Limited	Novel compounds
US11530200B2 (en)	2018-03-02	2022-12-20	Inflazome Limited	Compounds
US12168653B2 (en)	2018-03-02	2024-12-17	Inflazome Limited	Sulfonamide derivates as NLRP3 inhibitors
WO2019166619A1 (en)	2018-03-02	2019-09-06	Inflazome Limited	Novel compounds
US20220267276A1 (en)	2018-07-03	2022-08-25	Novartis Ag	Nlrp modulators
WO2020018970A1 (en) *	2018-07-20	2020-01-23	Genentech, Inc.	Sulfonylurea compounds as inhibitors of interleukin-1 activity
US20210236599A1 (en)	2018-08-13	2021-08-05	Iltoo Pharma	Combination of interleukin-2 with an interleukin 1 inhibitor, conjugates and therapeutic uses thereof
MA53221A (fr)	2018-08-15	2022-04-27	Inflazome Ltd	Nouveaux composés de sulfonamide urée
JP2022505525A (ja) *	2018-10-24	2022-01-14	ノバルティスアーゲー	Ｎｌｒｐ活性に関連する状態を治療するための化合物及び組成物
DK3911631T3 (da)	2019-01-14	2025-02-03	Zydus Lifesciences Ltd	Hidtil ukendte, substituerede sulfonylureaderivater
PT3983387T (pt)	2019-06-12	2024-07-10	Nodthera Ltd	Derivados de sulfonilurea e seus usos
EP3986879B1 (en)	2019-06-21	2024-10-02	AC Immune SA	Fused 1,2-thiazoles and 1,2-thiazines which act as nlrp3 modulators
CN114746087A (zh) *	2019-09-12	2022-07-12	载度思生命科学有限公司	新的经取代的亚砜亚胺衍生物
JP7504234B2 (ja) *	2020-06-11	2024-06-21	シーセンファーマシューティカルカンパニーリミテッド	ジメチルスルホキシミン誘導体
AU2021291065A1 (en)	2020-06-19	2022-12-15	Ac Immune Sa	Dihydrooxazole and thiourea derivatives modulating the NLRP3 inflammasome pathway
WO2022022646A1 (zh) *	2020-07-29	2022-02-03	南京明德新药研发有限公司	含硒五元杂芳环化合物
BR112023003792A2 (pt)	2020-09-04	2023-03-28	Nodthera Ltd	Derivados de sulfamoil ureia contendo porção alquil-oxacicloalquila e usos dos mesmos
ES2948511A1 (es) *	2021-09-08	2023-09-13	Fundacion Para La Investigacion Biomedica Del Hospital Univ De La Princesa	Derivados de n-sulfonilureas y su uso terapeutico
CN118355000A (zh) *	2021-12-03	2024-07-16	辰欣药业股份有限公司	二甲基亚磺酰亚胺衍生物的盐型及晶型
EP4452972A1 (en)	2021-12-22	2024-10-30	AC Immune SA	Dihydro-oxazol derivative compounds
CN118871426A (zh) *	2022-02-15	2024-10-29	豪夫迈·罗氏有限公司	用于制备1,2,3,5,6,7-六氢-s-二环戊二烯并苯衍生物的方法
WO2023222565A1 (en)	2022-05-16	2023-11-23	Institut National de la Santé et de la Recherche Médicale	Methods for assessing the exhaustion of hematopoietic stems cells induced by chronic inflammation
US20240034735A1 (en)	2022-07-14	2024-02-01	Ac Immune Sa	Novel compounds
AU2023313032A1 (en)	2022-07-28	2025-01-23	Ac Immune Sa	Novel compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4586950A (en) *	1982-05-31	1986-05-06	E. I. Du Pont De Nemours & Company	Novel phenyl-substituted sulfonamides
US4780125A (en) *	1982-09-01	1988-10-25	Ciba-Geigy Corporation	N-phenylsulfonyl-N'-triazinylureas
DE3927369A1 (de) *	1989-08-19	1991-02-21	Bayer Ag	Substituierte n-(chinolin-2-yl-methoxy)benzyl-sulfonyl-harnstoffe
US5064851A (en) *	1990-07-24	1991-11-12	Pfizer Inc.	3-(1-substituted-pyrazoyl)-2-oxindole derivatives, compositions and use
US5254589A (en) *	1991-10-15	1993-10-19	Warner-Lambert Company	Sulfonyl urea and carbamate ACAT inhibitors
DE4344957A1 (de) *	1993-12-30	1995-07-06	Hoechst Ag	Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Herstellungsverfahren und Verwendungsmöglichkeiten pharmazeutischer Präparate auf Basis dieser Verbindungen
CN1038679C (zh) *	1994-12-07	1998-06-10	南开大学	磺酰脲类化合物及其除草用途
HU226462B1 (en) *	1995-02-17	2008-12-29	Hoechst Ag	Substituted benzol-sulfonyl-ureas and -thioureas, process for producing them, pharmaceutical compositions containing them, and their use
AU6967198A (en) *	1997-04-10	1998-10-30	Eli Lilly And Company	Diarylsulfonylureas for use in treating secretory diarrhea

1997
- 1997-12-29 AT AT97947201T patent/ATE242208T1/de not_active IP Right Cessation
- 1997-12-29 EP EP97947201A patent/EP0964849B1/en not_active Expired - Lifetime
- 1997-12-29 CN CN97181579A patent/CN1127479C/zh not_active Expired - Fee Related
- 1997-12-29 WO PCT/IB1997/001603 patent/WO1998032733A1/en active IP Right Grant
- 1997-12-29 PL PL97335052A patent/PL335052A1/xx unknown
- 1997-12-29 BR BR9714328A patent/BR9714328A/pt not_active Application Discontinuation
- 1997-12-29 ID IDW990764A patent/ID22223A/id unknown
- 1997-12-29 DE DE69722663T patent/DE69722663T2/de not_active Expired - Fee Related
- 1997-12-29 KR KR1019997006786A patent/KR100324058B1/ko not_active IP Right Cessation
- 1997-12-29 EA EA199900603A patent/EA001803B1/ru not_active IP Right Cessation
- 1997-12-29 HU HU0000567A patent/HUP0000567A3/hu unknown
- 1997-12-29 IL IL13085597A patent/IL130855A0/xx unknown
- 1997-12-29 DE DE69729762T patent/DE69729762T2/de not_active Expired - Fee Related
- 1997-12-29 US US09/341,782 patent/US6166064A/en not_active Expired - Fee Related
- 1997-12-29 DK DK97947201T patent/DK0964849T3/da active
- 1997-12-29 CA CA002279186A patent/CA2279186C/en not_active Expired - Fee Related
- 1997-12-29 ES ES02020749T patent/ES2222426T3/es not_active Expired - Lifetime
- 1997-12-29 ES ES97947201T patent/ES2198598T3/es not_active Expired - Lifetime
- 1997-12-29 YU YU33799A patent/YU33799A/sh unknown
- 1997-12-29 TR TR1999/01816T patent/TR199901816T2/xx unknown
- 1997-12-29 AU AU52340/98A patent/AU723895B2/en not_active Ceased
- 1997-12-29 PT PT02020749T patent/PT1270565E/pt unknown
- 1997-12-29 DK DK02020749T patent/DK1270565T3/da active
- 1997-12-29 NZ NZ336248A patent/NZ336248A/xx unknown
- 1997-12-29 CZ CZ19992575A patent/CZ293173B6/cs not_active IP Right Cessation
- 1997-12-29 AT AT02020749T patent/ATE270285T1/de not_active IP Right Cessation
- 1997-12-29 SK SK982-99A patent/SK283679B6/sk unknown
- 1997-12-29 PT PT97947201T patent/PT964849E/pt unknown
- 1997-12-29 JP JP51868798A patent/JP3573757B2/ja not_active Expired - Fee Related
1998
- 1998-01-16 PA PA19988444701A patent/PA8444701A1/es unknown
- 1998-01-20 UY UY24861A patent/UY24861A1/es unknown
- 1998-01-23 PE PE1998000051A patent/PE57898A1/es not_active Application Discontinuation
- 1998-01-26 TW TW087101087A patent/TW515788B/zh not_active IP Right Cessation
- 1998-01-27 AR ARP980100358A patent/AR011093A1/es not_active Application Discontinuation
- 1998-01-27 DZ DZ980017A patent/DZ2407A1/xx active
- 1998-01-27 HR HR980045A patent/HRP980045B1/xx not_active IP Right Cessation
- 1998-01-28 MA MA24947A patent/MA26468A1/fr unknown
- 1998-01-28 ZA ZA9800685A patent/ZA98685B/xx unknown
- 1998-01-28 TN TNTNSN98017A patent/TNSN98017A1/fr unknown
- 1998-01-29 AP APAP/P/1998/001190A patent/AP929A/en active
- 1998-01-29 CO CO98004326A patent/CO4920230A1/es unknown
1999
- 1999-06-29 IS IS5099A patent/IS5099A/is unknown
- 1999-07-22 BG BG103597A patent/BG103597A/bg unknown
- 1999-07-23 OA OA9900165A patent/OA11079A/en unknown
- 1999-07-28 NO NO19993658A patent/NO313279B1/no not_active IP Right Cessation
2000
- 2000-10-31 US US09/703,142 patent/US6433009B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE69722663D1 (de)	2003-07-10
PE57898A1 (es)	1999-06-11
US6166064A (en)	2000-12-26
HUP0000567A3 (en)	2002-10-28
AU723895B2 (en)	2000-09-07
HUP0000567A2 (hu)	2000-10-28
SK98299A3 (en)	2001-10-08
EP0964849B1 (en)	2003-06-04
KR20000070541A (ko)	2000-11-25
DK1270565T3 (da)	2004-10-04
SK283679B6 (sk)	2003-11-04
PA8444701A1 (es)	2000-05-24
NO993658L (no)	1999-09-28
ID22223A (id)	1999-09-16
DK0964849T3 (da)	2003-08-25
NO313279B1 (no)	2002-09-09
TR199901816T2 (xx)	1999-11-22
EA199900603A1 (ru)	2000-02-28
PT1270565E (pt)	2004-09-30
CN1127479C (zh)	2003-11-12
AR011093A1 (es)	2000-08-02
YU33799A (sh)	2002-03-18
IL130855A0 (en)	2001-01-28
BR9714328A (pt)	2000-03-21
EA001803B1 (ru)	2001-08-27
US6433009B1 (en)	2002-08-13
CZ257599A3 (cs)	2000-09-13
ES2198598T3 (es)	2004-02-01
CN1245490A (zh)	2000-02-23
DE69729762T2 (de)	2005-07-14
UY24861A1 (es)	2000-09-29
WO1998032733A1 (en)	1998-07-30
CA2279186C (en)	2004-02-24
CO4920230A1 (es)	2000-05-29
CZ293173B6 (cs)	2004-02-18
KR100324058B1 (ko)	2002-02-16
PL335052A1 (en)	2000-03-27
EP0964849A1 (en)	1999-12-22
AP9801190A0 (en)	1998-03-31
AU5234098A (en)	1998-08-18
TNSN98017A1 (fr)	2005-03-15
BG103597A (bg)	2000-02-29
ATE242208T1 (de)	2003-06-15
IS5099A (is)	1999-06-29
HRP980045B1 (en)	2002-10-31
CA2279186A1 (en)	1998-07-30
OA11079A (en)	2002-03-14
ZA98685B (en)	1999-07-29
ATE270285T1 (de)	2004-07-15
NO993658D0 (no)	1999-07-28
JP3573757B2 (ja)	2004-10-06
MA26468A1 (fr)	2004-12-20
DE69722663T2 (de)	2004-04-29
AP929A (en)	2001-01-18
NZ336248A (en)	2000-10-27
TW515788B (en)	2003-01-01
JP2000511200A (ja)	2000-08-29
ES2222426T3 (es)	2005-02-01
PT964849E (pt)	2003-08-29
DE69729762D1 (de)	2004-08-05
HRP980045A2 (en)	1999-06-30

Publication	Publication Date	Title
DZ2407A1 (fr)	2003-01-04	Dérivés de sulfonylurée procédé pour leur préparation et compositions pharmaceutiques les contenant
DZ2197A1 (fr)	2002-12-02	Dérivés de 6-phénylpyridyl-2-amine, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2300A1 (fr)	2002-12-25	Dérivés 6,5-hétérobicycliques substitués, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2299A1 (fr)	2002-12-25	Dérivés 6,6-hétérobicycliques substitués, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2394A1 (fr)	2003-06-04	Dérivés de quinoléine et dérivés de quinazoline nouveax procédé pour leur préparation et compositions pharmaceutiques les contenant
DZ2581A1 (fr)	2003-02-22	Dérivés d'acides aryloxyarylsulfonylaminohydroxamiques procédé pour leur préparation et compositionspharmaceutiques les contenant.
CY2537B1 (fr)	2006-06-28	Composés hétérocycliques substitués, procédé pour leur préparation et compositions pharmaceutiques les contenant
DZ2303A1 (fr)	2002-12-28	Dérivés d'indazole nouveaux procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2758A1 (fr)	2003-09-15	Dérivés bicycliques d0acide hydroxamique nouveaux procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ1889A1 (fr)	2002-02-17	Dérivés de quinoléine nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2666A1 (fr)	2003-03-22	Dérivés d'acide hydroxamique compositions pharmaceutiques les contenant et procédé pour leur préparation.
DZ1957A1 (fr)	2002-02-17	Dérivés de pipéridine nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2360A1 (fr)	2002-12-28	Dérivés de pyrazole procédé pour leur préparation et compositions les contenant
DZ2773A1 (fr)	2003-12-01	Pyrazolopyrimidinones nouvelles procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2550A1 (fr)	2003-02-08	Dérivés d'azétidinylpropylpipéridine procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2777A1 (fr)	2003-12-01	Dérivés de quinazolinamines nouveaux procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2745A1 (fr)	2003-09-08	BicycloÄ2.2.1Üheptanes nouveaux procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2414A1 (fr)	2003-01-04	2-amino-6-(2-substitué-4-phenoxy)substituté-pyridines procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2963A1 (fr)	2004-03-15	Dérivés de bicycliques substituées nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2634A1 (fr)	2003-03-08	Dérivés de pleuromutiline nouveaux procédé pour leur préparation et compositions pharmaceutiques lescontenant.
DZ2416A1 (fr)	2003-01-04	Dérivés d'acide arylsulfonylhydroxamique procédé pour leur préparation et compositions les contenant.
EP0718287A3 (de)	1997-01-29	Piperazinderivate, diese Verbindungen enthaltende Arzneimittel, deren Verwendungen und Verfahren zu ihrer Herstellung
MA26659A1 (fr)	2004-12-20	Dérivés de benzimidazole nouveaux, compositions pharmaceutiques les contenant et procédé pour leur préparation.
DZ2891A1 (fr)	2003-12-15	Dérivés de tétrahydroquinoléines substués nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2621A1 (fr)	2003-03-08	AGonistes de prostaglandines nouveaux procédé pourleur préparation et compositions pharmaceutiques les contenant.