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DK98688D0 - Heterocyclyl-2-propyn-1-aminer og anvendelse deraf til behandling af hypertension - Google Patents

Heterocyclyl-2-propyn-1-aminer og anvendelse deraf til behandling af hypertension

Info

Publication number
DK98688D0
DK98688D0 DK098688A DK98688A DK98688D0 DK 98688 D0 DK98688 D0 DK 98688D0 DK 098688 A DK098688 A DK 098688A DK 98688 A DK98688 A DK 98688A DK 98688 D0 DK98688 D0 DK 98688D0
Authority
DK
Denmark
Prior art keywords
propyn
heterocyclyl
amines
application
treating hypertension
Prior art date
Application number
DK098688A
Other languages
English (en)
Other versions
DK98688A (da
Inventor
Thomas M Bargar
Lawrence C Creemer
James R Mccarthy
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK98688D0 publication Critical patent/DK98688D0/da
Publication of DK98688A publication Critical patent/DK98688A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
DK098688A 1987-02-26 1988-02-25 Heterocyclyl-2-propyn-1-aminer og anvendelse deraf til behandling af hypertension DK98688A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1910387A 1987-02-26 1987-02-26

Publications (2)

Publication Number Publication Date
DK98688D0 true DK98688D0 (da) 1988-02-25
DK98688A DK98688A (da) 1988-08-27

Family

ID=21791457

Family Applications (1)

Application Number Title Priority Date Filing Date
DK098688A DK98688A (da) 1987-02-26 1988-02-25 Heterocyclyl-2-propyn-1-aminer og anvendelse deraf til behandling af hypertension

Country Status (15)

Country Link
EP (1) EP0281018A1 (da)
JP (1) JP2524513B2 (da)
KR (1) KR880009925A (da)
CN (1) CN88101039A (da)
AU (1) AU596501B2 (da)
CA (1) CA1309719C (da)
DK (1) DK98688A (da)
FI (1) FI880909A (da)
HU (1) HU200602B (da)
IL (1) IL85524A0 (da)
NO (1) NO880834L (da)
NZ (1) NZ223583A (da)
PH (1) PH23656A (da)
PT (1) PT86837B (da)
ZA (1) ZA881227B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ214697A (en) * 1984-12-31 1988-10-28 Merrell Dow Pharma B-methylene-2- and 3-furanethanamine and pharmaceutical compositions
JP3937489B2 (ja) * 1996-05-31 2007-06-27 住友化学株式会社 プロパルギルアミン化合物の製造方法
CN103030580A (zh) * 2012-12-13 2013-04-10 山东铂源药业有限公司 一种拉帕替尼中间体的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2299332A1 (fr) * 1975-01-31 1976-08-27 Parcor Procede de preparation de la (thienyl-2)-2-ethylamine et de ses derives
FR2508456A1 (fr) * 1981-06-30 1982-12-31 Sanofi Sa Procede de preparation de (thienyl-2)-2 ethylamines et (thienyl-3)-2 ethylamines
NZ214697A (en) * 1984-12-31 1988-10-28 Merrell Dow Pharma B-methylene-2- and 3-furanethanamine and pharmaceutical compositions
NZ214698A (en) * 1984-12-31 1988-08-30 Merrell Dow Pharma Thiophene derivatives and pharmaceutical compositions containing such
FR2608607B1 (fr) * 1986-12-23 1989-04-28 Sanofi Sa Procede de preparation de thienylethylamines et dithienylethylamines ainsi obtenues

Also Published As

Publication number Publication date
NZ223583A (en) 1990-02-26
AU596501B2 (en) 1990-05-03
JP2524513B2 (ja) 1996-08-14
ZA881227B (en) 1988-10-26
KR880009925A (ko) 1988-10-05
JPS63227581A (ja) 1988-09-21
HU200602B (en) 1990-07-28
NO880834D0 (no) 1988-02-25
AU1217388A (en) 1988-09-01
CN88101039A (zh) 1988-10-05
NO880834L (no) 1988-08-29
IL85524A0 (en) 1988-08-31
PH23656A (en) 1989-09-27
DK98688A (da) 1988-08-27
CA1309719C (en) 1992-11-03
HUT49337A (en) 1989-09-28
PT86837B (pt) 1992-05-29
FI880909A0 (fi) 1988-02-26
FI880909A (fi) 1988-08-27
EP0281018A1 (en) 1988-09-07
PT86837A (pt) 1988-03-01

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment