|
US4873088A
(en)
*
|
1983-09-06 |
1989-10-10 |
Liposome Technology, Inc. |
Liposome drug delivery method and composition
|
|
JPS6058915A
(ja)
*
|
1983-09-12 |
1985-04-05 |
Fujisawa Pharmaceut Co Ltd |
薬物含有脂質小胞体製剤
|
|
EP0152379A3
(de)
*
|
1984-02-15 |
1986-10-29 |
Ciba-Geigy Ag |
Verfahren zur Herstellung von pharmazeutischen Zusammensetzungen enthaltend unilamellare Liposomen
|
|
CH668554A5
(de)
*
|
1984-04-09 |
1989-01-13 |
Sandoz Ag |
Liposomen welche polypeptide mit interleukin-2-aktivitaet enthalten sowie verfahren zu ihrer herstellung.
|
|
US5283122A
(en)
*
|
1984-04-19 |
1994-02-01 |
University Of Tennessee Research Corporation |
Fused liposome and acid induced method for liposome fusion
|
|
CA1260393A
(en)
*
|
1984-10-16 |
1989-09-26 |
Lajos Tarcsay |
Liposomes of synthetic lipids
|
|
US4921706A
(en)
*
|
1984-11-20 |
1990-05-01 |
Massachusetts Institute Of Technology |
Unilamellar lipid vesicles and method for their formation
|
|
AU587600B2
(en)
*
|
1985-01-11 |
1989-08-24 |
Regents Of The University Of California, The |
Method for preserving liposomes
|
|
US4740375A
(en)
*
|
1985-02-25 |
1988-04-26 |
Technology Unlimited, Inc. |
Gelcores
|
|
US4736051A
(en)
*
|
1985-03-20 |
1988-04-05 |
Kao Corporation |
Process for the preparation of an alkali metal salt of a diester phosphoric acid
|
|
US5622713A
(en)
*
|
1985-09-17 |
1997-04-22 |
The Regents Of The University Of California |
Method of detoxifying animal suffering from overdose
|
|
IE58981B1
(en)
*
|
1985-10-15 |
1993-12-15 |
Vestar Inc |
Anthracycline antineoplastic agents encapsulated in phospholipid micellular particles
|
|
MY101125A
(en)
*
|
1985-12-23 |
1991-07-31 |
Kao Corp |
Gel-like emulsion and o/w emulsions obtained from gel-like emulsion
|
|
US4923854A
(en)
*
|
1986-01-22 |
1990-05-08 |
The Liposome Company, Inc. |
Solubilization of hydrophobic materials using lysophospholipid
|
|
US4888288A
(en)
*
|
1986-01-30 |
1989-12-19 |
Becton Dickinson And Company |
Vesicles resistant to enzyme lysis and use thereof in an enzyme assay
|
|
US5204112A
(en)
*
|
1986-06-16 |
1993-04-20 |
The Liposome Company, Inc. |
Induction of asymmetry in vesicles
|
|
US5252263A
(en)
*
|
1986-06-16 |
1993-10-12 |
The Liposome Company, Inc. |
Induction of asymmetry in vesicles
|
|
JP2760355B2
(ja)
*
|
1986-06-16 |
1998-05-28 |
ザ リポソーム カンパニー，インコーポレイテッド |
不均整誘導リポソーム
|
|
JPS63182029A
(ja)
*
|
1987-01-22 |
1988-07-27 |
Agency Of Ind Science & Technol |
リポソ−ム
|
|
CA1323306C
(en)
*
|
1987-03-05 |
1993-10-19 |
Mircea C. Popescu |
Pharmacological agent-lipid solution preparation
|
|
US4963297A
(en)
*
|
1987-12-22 |
1990-10-16 |
The Liposome Company, Inc. |
Spontaneous vesticulation of multilamellar liposomes
|
|
MX9203808A
(es)
*
|
1987-03-05 |
1992-07-01 |
Liposome Co Inc |
Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos.
|
|
CA1338702C
(en)
*
|
1987-03-05 |
1996-11-12 |
Lawrence D. Mayer |
High drug:lipid formulations of liposomal- antineoplastic agents
|
|
US5154930A
(en)
*
|
1987-03-05 |
1992-10-13 |
The Liposome Company, Inc. |
Pharmacological agent-lipid solution preparation
|
|
FR2616328B1
(fr)
*
|
1987-06-12 |
1990-03-02 |
Moet Hennessy Rech |
Composition a base de phases lamellaires lipidiques hydratees ou de liposomes contenant un extrait de murier, ou au moins une flavone, en particulier une kuwanone et composition pharmaceutique, notamment dermatologique, a activite depigmentante, ou anti-inflammatoire, ou cosmetique, l'incorporant
|
|
AU618972B2
(en)
*
|
1987-10-06 |
1992-01-16 |
Houston Biotechnology Incorporated |
Phosphatidyl treatment of viral disease
|
|
US4946683A
(en)
*
|
1987-11-18 |
1990-08-07 |
Vestar, Inc. |
Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes
|
|
EP0393145A4
(en)
*
|
1987-12-22 |
1991-09-11 |
The Liposome Company, Inc. |
Spontaneous vesiculation of multilamellar liposomes
|
|
US5133965A
(en)
*
|
1988-06-08 |
1992-07-28 |
Fountain Pharmaceuticals, Inc. |
Dressing material having adsorbed thereon a solvent dilution microcarrier precursor solution
|
|
US5269979A
(en)
*
|
1988-06-08 |
1993-12-14 |
Fountain Pharmaceuticals, Inc. |
Method for making solvent dilution microcarriers
|
|
FR2638639A1
(fr)
*
|
1988-11-08 |
1990-05-11 |
Parincos Parfumerie Cosmet Int |
Composition et procede d'obtention de liposomes oligolamellaires en vue d'une application en cosmetologie et dermatologie topique
|
|
US5153000A
(en)
*
|
1988-11-22 |
1992-10-06 |
Kao Corporation |
Phosphate, liposome comprising the phosphate as membrane constituent, and cosmetic and liposome preparation comprising the liposome
|
|
US5015483A
(en)
*
|
1989-02-09 |
1991-05-14 |
Nabisco Brands, Inc. |
Liposome composition for the stabilization of oxidizable substances
|
|
US5139803A
(en)
*
|
1989-02-09 |
1992-08-18 |
Nabisco, Inc. |
Method and liposome composition for the stabilization of oxidizable substances
|
|
US4994440A
(en)
*
|
1989-02-13 |
1991-02-19 |
Creaven Patrick J |
Method for the treatment of renal cell carcinoma
|
|
US5116964A
(en)
|
1989-02-23 |
1992-05-26 |
Genentech, Inc. |
Hybrid immunoglobulins
|
|
WO1990012565A1
(en)
*
|
1989-04-25 |
1990-11-01 |
Nattermann, A. & Cie. Gmbh |
Water-containing formulations with phospholipids
|
|
DE3919982A1
(de)
*
|
1989-06-19 |
1990-12-20 |
Liedtke Pharmed Gmbh |
Orale lipidarzneiform
|
|
US5290563A
(en)
*
|
1989-07-27 |
1994-03-01 |
Laboratoire Des Stallergenes |
Method for combining a mixture of heterogeneous substances with liposomes
|
|
GB8918879D0
(en)
*
|
1989-08-18 |
1989-09-27 |
Danbiosyst Uk |
Pharmaceutical compositions
|
|
DE4005711C1
(da)
*
|
1990-02-23 |
1991-06-13 |
A. Nattermann & Cie Gmbh, 5000 Koeln, De |
|
|
DE4013632A1
(de)
*
|
1990-04-27 |
1991-10-31 |
Max Planck Gesellschaft |
Liposomen mit positiver ueberschussladung
|
|
US5165994A
(en)
*
|
1990-06-05 |
1992-11-24 |
University Of Delaware |
Spontaneous equilbrium surfactant vesicles
|
|
DE4018767A1
(de)
*
|
1990-06-12 |
1991-12-19 |
Braun Melsungen Ag |
Wirkstofffreie liposomen zur behandlung von atherosklerose
|
|
EP0467838A3
(en)
*
|
1990-07-17 |
1992-09-02 |
Ciba-Geigy Ag |
Process for preparing an injectable liposome dispersion
|
|
CA2046830C
(en)
|
1990-07-19 |
1999-12-14 |
Patrick P. Deluca |
Drug delivery system involving inter-action between protein or polypeptide and hydrophobic biodegradable polymer
|
|
FR2674128A1
(fr)
*
|
1991-03-19 |
1992-09-25 |
Patrinove |
"vecteurs de structure capsulaire" et leurs applications dans le transport de substances ou principes actifs.
|
|
US6764693B1
(en)
|
1992-12-11 |
2004-07-20 |
Amaox, Ltd. |
Free radical quenching composition and a method to increase intracellular and/or extracellular antioxidants
|
|
US5720973A
(en)
*
|
1993-02-18 |
1998-02-24 |
Knoll Aktiengesellschaft |
Preparation of colloidal aqueous solutions of active substances of low solubility and a lipid therefor
|
|
GB9320668D0
(en)
*
|
1993-10-07 |
1993-11-24 |
Secr Defence |
Liposomes containing particulare materials
|
|
US5840328A
(en)
*
|
1994-01-11 |
1998-11-24 |
The Liposome Company, Inc. |
Treatment using arachidonic acid metabolite and particulate formulations
|
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
|
US5708142A
(en)
|
1994-05-27 |
1998-01-13 |
Genentech, Inc. |
Tumor necrosis factor receptor-associated factors
|
|
DE4423131A1
(de)
*
|
1994-07-01 |
1996-01-04 |
Bayer Ag |
Neue hIL-4-Mutantenproteine als Antagonisten oder partielle Agonisten des humanen Interleukin 4
|
|
IT1270678B
(it)
*
|
1994-10-20 |
1997-05-07 |
Bayer Ag |
Liposomi al chetoprofen
|
|
US6093697A
(en)
*
|
1994-11-07 |
2000-07-25 |
The University Of Virginia Patent Foundation |
Synthetic insulin mimetic substances
|
|
US20020048596A1
(en)
*
|
1994-12-30 |
2002-04-25 |
Gregor Cevc |
Preparation for the transport of an active substance across barriers
|
|
US7517858B1
(en)
*
|
1995-06-07 |
2009-04-14 |
The Regents Of The University Of California |
Prodrugs of pharmaceuticals with improved bioavailability
|
|
US20040208922A1
(en)
*
|
1995-06-07 |
2004-10-21 |
The Regents Of The University Of California |
Method for loading lipid like vesicles with drugs or other chemicals
|
|
US7888466B2
(en)
|
1996-01-11 |
2011-02-15 |
Human Genome Sciences, Inc. |
Human G-protein chemokine receptor HSATU68
|
|
US6183774B1
(en)
|
1996-01-31 |
2001-02-06 |
Collaborative Laboratories, Inc. |
Stabilizing vitamin A derivatives by encapsulation in lipid vesicles formed with alkylammonium fatty acid salts
|
|
US5874105A
(en)
*
|
1996-01-31 |
1999-02-23 |
Collaborative Laboratories, Inc. |
Lipid vesicles formed with alkylammonium fatty acid salts
|
|
US6071535A
(en)
*
|
1996-01-31 |
2000-06-06 |
Collaborative Laboratories, Inc. |
Lipid vesicles formed with alkylammonium fatty acid salts
|
|
US6723531B2
(en)
|
1996-04-05 |
2004-04-20 |
The Salk Institute For Biological Studies |
Method for modulating expression of exogenous genes in mammalian systems, and products related thereto
|
|
US5766877A
(en)
*
|
1996-05-10 |
1998-06-16 |
Amgen Inc. |
Genes encoding art, an agouti-related transcript
|
|
NZ334309A
(en)
|
1996-10-25 |
2000-08-25 |
Human Genome Sciences Inc |
Neutrokine alpha protein, a member of the TNF family, and its use in treating and/or detecting immune disorders
|
|
US6156728A
(en)
*
|
1996-11-01 |
2000-12-05 |
Genentech, Inc. |
Treatment of inner ear hair cells
|
|
US6593290B1
(en)
|
1996-11-01 |
2003-07-15 |
Genentech, Inc. |
Treatment of inner ear hair cells
|
|
US7390891B1
(en)
|
1996-11-15 |
2008-06-24 |
Amgen Inc. |
Polynucleotides encoding a telomerase component TP2
|
|
US5919656A
(en)
*
|
1996-11-15 |
1999-07-06 |
Amgen Canada Inc. |
Genes encoding telomerase protein 1
|
|
US5935572A
(en)
*
|
1997-01-10 |
1999-08-10 |
Collaborative Laboratories, Inc. |
Composition containing protease separate from glycosidase for removing nits in treating lice infestation
|
|
US5827532A
(en)
*
|
1997-01-31 |
1998-10-27 |
The Reagents Of The University Of California |
Method for loading lipsomes with ionizable phosphorylated hydrophobic compounds, pharmaceutical preparations and a method for administering the preparations
|
|
WO1998054206A1
(en)
|
1997-05-30 |
1998-12-03 |
Human Genome Sciences, Inc. |
32 human secreted proteins
|
|
US6103706A
(en)
*
|
1997-04-29 |
2000-08-15 |
New York Blood Center, Inc. |
Methods for treating viral infections
|
|
US6113947A
(en)
*
|
1997-06-13 |
2000-09-05 |
Genentech, Inc. |
Controlled release microencapsulated NGF formulation
|
|
US6663899B2
(en)
|
1997-06-13 |
2003-12-16 |
Genentech, Inc. |
Controlled release microencapsulated NGF formulation
|
|
US6300488B1
(en)
|
1997-07-10 |
2001-10-09 |
The Salk Institute For Biological Studies |
Modified lepidopteran receptors and hybrid multifunctional proteins for use in transcription and regulation of transgene expression
|
|
US6342220B1
(en)
|
1997-08-25 |
2002-01-29 |
Genentech, Inc. |
Agonist antibodies
|
|
CA2303200A1
(en)
*
|
1997-09-04 |
1999-03-11 |
Brian C. Keller |
Oral liposomal delivery system
|
|
US6165997A
(en)
*
|
1997-11-20 |
2000-12-26 |
Statens Serum Institut |
Phospholipids having antimicrobial activity with or without the presence of antimicrobials
|
|
AU1417999A
(en)
*
|
1997-11-21 |
1999-06-15 |
Human Genome Sciences, Inc. |
Chemokine alpha-5
|
|
US5906979A
(en)
*
|
1998-01-27 |
1999-05-25 |
Insmed Pharmaceuticals, Inc. |
Compositions and methods for treating metabolic diseases characterized by hyperandrogenism and/or anovulation and/or infertility
|
|
EP1510579B1
(en)
|
1998-02-04 |
2009-08-05 |
Genentech, Inc. |
Use of heregulin as an epithelial cell growth factor
|
|
NZ525914A
(en)
|
1998-03-10 |
2004-03-26 |
Genentech Inc |
Novel polypeptides and nucleic acids encoding the same
|
|
AU758353B2
(en)
|
1998-03-17 |
2003-03-20 |
Genentech Inc. |
Polypeptides homologous to VEGF and BMP1
|
|
US6949528B1
(en)
*
|
1998-03-18 |
2005-09-27 |
Goddard John G |
Compositions containing lysophosphatidic acids which inhibit apoptosis and uses thereof
|
|
EP1093457B8
(en)
|
1998-03-19 |
2011-02-02 |
Human Genome Sciences, Inc. |
Cytokine receptor common gamma chain like
|
|
US6333318B1
(en)
|
1998-05-14 |
2001-12-25 |
The Salk Institute For Biological Studies |
Formulations useful for modulating expression of exogenous genes in mammalian systems, and products related thereto
|
|
US5973119A
(en)
*
|
1998-06-05 |
1999-10-26 |
Amgen Inc. |
Cyclin E genes and proteins
|
|
US6344541B1
(en)
|
1998-09-25 |
2002-02-05 |
Amgen Inc. |
DKR polypeptides
|
|
AUPP785098A0
(en)
|
1998-12-21 |
1999-01-21 |
Victor Chang Cardiac Research Institute, The |
Treatment of heart disease
|
|
PL193824B1
(pl)
*
|
1998-12-23 |
2007-03-30 |
Idea Ag |
Preparat zawierający środki penetrujące, sposób wytwarzania preparatu zawierającego środki penetrujące oraz zastosowanie preparatu do wytwarzania leku
|
|
EP1031346B1
(en)
|
1999-01-27 |
2002-05-02 |
Idea Ag |
Noninvasive vaccination through the skin
|
|
ES2173679T3
(es)
|
1999-01-27 |
2002-10-16 |
Idea Ag |
Inmunizacion/transporte transnasal con vehiculos altamente adaptables.
|
|
US6303749B1
(en)
|
1999-01-29 |
2001-10-16 |
Amgen Inc. |
Agouti and agouti-related peptide analogs
|
|
JP5000804B2
(ja)
*
|
1999-02-03 |
2012-08-15 |
アムジエン・インコーポレーテツド |
免疫応答に関与する新規ポリペプチド
|
|
US7708993B2
(en)
|
1999-02-03 |
2010-05-04 |
Amgen Inc. |
Polypeptides involved in immune response
|
|
US7435796B1
(en)
|
1999-02-03 |
2008-10-14 |
Amgen Inc. |
Antibodies which bind B7RP1
|
|
US8624010B1
(en)
|
1999-02-03 |
2014-01-07 |
Steven K. Yoshinaga |
Nucleic acids encoding B7RP1
|
|
JP2002537769A
(ja)
|
1999-02-26 |
2002-11-12 |
ヒューマン ジノーム サイエンシーズ， インコーポレイテッド |
ヒトエンドカインαおよび使用方法
|
|
AU3770800A
(en)
|
1999-03-26 |
2000-10-16 |
Amgen, Inc. |
Beta secretase genes and polypeptides
|
|
US6635249B1
(en)
|
1999-04-23 |
2003-10-21 |
Cenes Pharmaceuticals, Inc. |
Methods for treating congestive heart failure
|
|
MXPA02000053A
(es)
*
|
1999-07-05 |
2003-07-21 |
Idea Ag |
Un metodo para mejorar el tratamiento a traves de barreras adaptables semipermeables.
|
|
US7408047B1
(en)
|
1999-09-07 |
2008-08-05 |
Amgen Inc. |
Fibroblast growth factor-like polypeptides
|
|
US7459540B1
(en)
|
1999-09-07 |
2008-12-02 |
Amgen Inc. |
Fibroblast growth factor-like polypeptides
|
|
US7057015B1
(en)
|
1999-10-20 |
2006-06-06 |
The Salk Institute For Biological Studies |
Hormone receptor functional dimers and methods of their use
|
|
US6372722B1
(en)
|
2000-01-19 |
2002-04-16 |
Genteric, Inc. |
Method for nucleic acid transfection of cells
|
|
US20030103978A1
(en)
|
2000-02-23 |
2003-06-05 |
Amgen Inc. |
Selective binding agents of osteoprotegerin binding protein
|
|
US7514239B2
(en)
|
2000-03-28 |
2009-04-07 |
Amgen Inc. |
Nucleic acid molecules encoding beta-like glycoprotein hormone polypeptides and heterodimers thereof
|
|
EP1274719A4
(en)
|
2000-04-12 |
2004-05-19 |
Human Genome Sciences Inc |
ALBUMIN FUSED PROTEINS
|
|
AU2001282856A1
(en)
|
2000-06-15 |
2001-12-24 |
Human Genome Sciences, Inc. |
Human tumor necrosis factor delta and epsilon
|
|
CA2648048A1
(en)
|
2000-06-23 |
2002-01-03 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
|
|
EP2042597B1
(en)
|
2000-06-23 |
2014-05-07 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
|
|
AU7026601A
(en)
|
2000-06-28 |
2002-01-08 |
Amgen Inc |
Thymic stromal lymphopoietin receptor molecules and uses thereof
|
|
EP2351840A1
(en)
|
2000-11-28 |
2011-08-03 |
Amgen Inc. |
Polypeptides involved in immune response
|
|
US6989247B2
(en)
|
2000-11-28 |
2006-01-24 |
Celltech R & D, Inc. |
Compositions and methods for diagnosing or treating psoriasis
|
|
US7087726B2
(en)
|
2001-02-22 |
2006-08-08 |
Genentech, Inc. |
Anti-interferon-α antibodies
|
|
GB0111628D0
(en)
|
2001-05-11 |
2001-07-04 |
Scancell Ltd |
Binding member
|
|
AUPR546801A0
(en)
|
2001-06-05 |
2001-06-28 |
Commonwealth Scientific And Industrial Research Organisation |
Recombinant antibodies
|
|
PL222211B1
(pl)
|
2001-06-26 |
2016-07-29 |
Amgen Fremont Inc |
Przeciwciało przeciwko OPGL, kompozycja je zawierająca, jego zastosowanie i sposób jego wytwarzania, sposób wykrywania poziomu OPGL, kompozycja obejmująca polinukleotydy i komórka gosodarza
|
|
WO2003002187A2
(en)
*
|
2001-06-26 |
2003-01-09 |
Photomed Technologies, Inc. |
Multiple wavelength illuminator
|
|
JP4399260B2
(ja)
|
2001-08-24 |
2010-01-13 |
ニューレン ファーマシューティカルズ リミテッド |
神経再生ペプチドおよび脳損傷治療におけるその使用方法
|
|
PL368972A1
(en)
|
2001-08-29 |
2005-04-04 |
Genentech, Inc. |
Bv8 nucleic acids and polypeptides with mitogenic activity
|
|
GB0121709D0
(en)
*
|
2001-09-07 |
2001-10-31 |
Imp College Innovations Ltd |
Food inhibition agent
|
|
ES2320979T3
(es)
|
2001-09-24 |
2009-06-01 |
Imperial Innovations Limited |
Pyy-36 para la reduccion o prevencion de la obesidad.
|
|
EP1930420A1
(en)
|
2001-09-26 |
2008-06-11 |
Merck & Co., Inc. |
Isolated nucleic acid molecules encoding a bacterial uracil phosphoribosyl-transferase enzyme, cells transformed therewith and uses thereof
|
|
EP1438434A4
(en)
*
|
2001-09-26 |
2006-03-08 |
Merck & Co Inc |
ISOLATED NUCLEIC ACID MOLECULES, TRANSFORMED CELLS AND USES THEREOF FOR A BACTERIAL URACIL TRANSPORT PROTEIN AND A BACTERIAL URACIL PHOSPHORIBOSYL TRANSFERASE ENZYME
|
|
DE10148067A1
(de)
*
|
2001-09-28 |
2003-04-17 |
Max Planck Gesellschaft |
Hitzesterilisierbare Alkylphosphocholin-Liposome
|
|
DE10148066A1
(de)
*
|
2001-09-28 |
2003-04-24 |
Max Planck Gesellschaft |
Liposome enthaltend (Ether)-Lysolecithine
|
|
US7521053B2
(en)
|
2001-10-11 |
2009-04-21 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
US7138370B2
(en)
|
2001-10-11 |
2006-11-21 |
Amgen Inc. |
Specific binding agents of human angiopoietin-2
|
|
US20040106773A1
(en)
*
|
2001-10-12 |
2004-06-03 |
Hao Wang |
Human tuberoinfundibular peptide of 39 residues
|
|
CA2462883A1
(en)
|
2001-10-12 |
2003-04-17 |
Schering Corporation |
Use of bispecific antibodies to regulate immune responses
|
|
ES2545090T3
(es)
|
2001-12-21 |
2015-09-08 |
Human Genome Sciences, Inc. |
Proteínas de fusión de albúmina y GCSF
|
|
JP4733922B2
(ja)
|
2002-01-10 |
2011-07-27 |
インペリアル・イノベ−ションズ・リミテッド |
摂食行動の修正
|
|
US8058233B2
(en)
*
|
2002-01-10 |
2011-11-15 |
Oregon Health And Science University |
Modification of feeding behavior using PYY and GLP-1
|
|
US7662924B2
(en)
|
2002-02-22 |
2010-02-16 |
The Board Of Trustees Of The University Of Illinois |
Beta chain-associated regulator of apoptosis
|
|
US20030180348A1
(en)
*
|
2002-03-22 |
2003-09-25 |
Levinson R. Saul |
Transcellular drug delivery system
|
|
EP2314316A1
(en)
|
2002-04-05 |
2011-04-27 |
Amgen, Inc |
Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors
|
|
AU2002304965A1
(en)
|
2002-05-24 |
2003-12-12 |
Zensun (Shanghai) Sci-Tech.Ltd |
Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
|
|
EP2305710A3
(en)
|
2002-06-03 |
2013-05-29 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
|
WO2007068784A1
(en)
|
2005-12-14 |
2007-06-21 |
Licentia Ltd |
Novel neurotrophic factor protein and uses thereof
|
|
DK2213685T3
(da)
|
2002-09-06 |
2014-03-03 |
Medarex Llc |
Terapeutisk anti-IL-1R1-monoklonalt antistof
|
|
KR100489701B1
(ko)
*
|
2002-10-09 |
2005-05-16 |
주식회사 태평양 |
고농도의 트리터페노이드를 함유하는 미소화 리포좀 및 그제조방법
|
|
US7473432B2
(en)
*
|
2002-10-11 |
2009-01-06 |
Idea Ag |
NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery
|
|
WO2004034988A2
(en)
|
2002-10-16 |
2004-04-29 |
Amgen Inc. |
Human anti-ifn-ϝ neutralizing antibodies as selective ifn-ϝ pathway inhibitors
|
|
CN100434440C
(zh)
|
2002-12-02 |
2008-11-19 |
阿布格尼克斯公司 |
针对肿瘤坏死因子的抗体及其用途
|
|
WO2004060911A2
(en)
*
|
2002-12-30 |
2004-07-22 |
Amgen Inc. |
Combination therapy with co-stimulatory factors
|
|
GB0300571D0
(en)
*
|
2003-01-10 |
2003-02-12 |
Imp College Innovations Ltd |
Modification of feeding behaviour
|
|
US7632810B2
(en)
|
2003-03-12 |
2009-12-15 |
Genentech, Inc. |
Compositions with hematopoietic and immune activity
|
|
US8067544B2
(en)
|
2003-03-19 |
2011-11-29 |
Curagen Corporation |
Antibodies against T cell immunoglobulin domain and mucin domain 1 (TIM-1) antigen and uses thereof
|
|
US7291590B2
(en)
|
2003-06-12 |
2007-11-06 |
Queen's University At Kingston |
Compositions and methods for treating atherosclerosis
|
|
KR101435167B1
(ko)
|
2003-06-27 |
2014-11-04 |
암젠 프레몬트 인코포레이티드 |
상피 성장 인자 수용체의 결실 돌연변이체 지향 항체 및 그용도
|
|
NZ544797A
(en)
|
2003-07-18 |
2011-04-29 |
Amgen Fremont Inc |
Specific antibodies that bind HGF and neutralise binding of HGF to met
|
|
NZ545940A
(en)
|
2003-09-12 |
2009-12-24 |
Tercica Inc |
Methods for treatment of insulin-like growth factor-1 (IGF-1) deficiency
|
|
CA2543484C
(en)
|
2003-10-27 |
2014-02-04 |
Amgen Inc. |
Modulation of immune response to an immunogen with ctla-4 and tnfbp
|
|
WO2005072159A2
(en)
*
|
2004-01-05 |
2005-08-11 |
Biotech Studio, Llc |
Biotherapeutics, diagnostics and research reagents
|
|
NZ548256A
(en)
*
|
2004-02-02 |
2010-02-26 |
Ambrx Inc |
Modified human four helical bundle polypeptides and their uses
|
|
EP2418224A3
(en)
|
2004-03-19 |
2013-07-24 |
Amgen Inc. |
Reducing the risk of human and anti-human antibodies through V gene manipulation
|
|
EP1726647B1
(en)
|
2004-03-19 |
2015-01-07 |
GenomIdea, Inc. |
Gene promoting vascular endothelial cell growth
|
|
JP2007530045A
(ja)
*
|
2004-03-23 |
2007-11-01 |
アムジエン・インコーポレーテツド |
ヒトｏｘ４０ｌ（ｃｄ１３４ｌ）特異性モノクローナル抗体
|
|
WO2005095633A1
(en)
*
|
2004-04-02 |
2005-10-13 |
Queen's University At Kingston |
A cell culture system for modelling serum amyloid a amyloidogenesis and identifying amyloid modulating compounds
|
|
GB0410627D0
(en)
|
2004-05-12 |
2004-06-16 |
Scancell Ltd |
Specific binding members
|
|
EP1598428A1
(en)
|
2004-05-18 |
2005-11-23 |
Georg Dewald |
Methods and kits to detect Hereditary angioedema type III
|
|
MXPA06014684A
(es)
|
2004-06-18 |
2007-02-12 |
Ambrx Inc |
Novedosos polipeptidos de enlace antigeno y sus usos.
|
|
WO2006009575A1
(en)
|
2004-06-22 |
2006-01-26 |
The Board Of Trustees Of The University Of Illinois |
METHODS OF INHIBITING TUMOR CELL PROLIFERATION WITH FOXM1 siRNA
|
|
ME00226B
(me)
|
2004-07-15 |
2011-02-10 |
Medarex Llc |
Humana anti-ngf neutrališuća antitijela kao selektivni inhibitori ngf signalne kaskade
|
|
AU2005327906B2
(en)
|
2004-07-21 |
2010-05-13 |
Ambrx, Inc. |
Biosynthetic polypeptides utilizing non-naturally encoded amino acids
|
|
CA2574881C
(en)
|
2004-08-04 |
2013-01-08 |
Amgen Inc. |
Antibodies to dkk-1
|
|
CA2577442A1
(en)
|
2004-08-17 |
2006-03-02 |
The Johns Hopkins University |
Pde5 inhibitor compositions and methods for treating cardiac indications
|
|
NZ554142A
(en)
|
2004-10-06 |
2009-12-24 |
Agri Biotech Pty Ltd |
Antibody production method comprising inserting antigen releasing device into mammal so antibodies are released into its milk
|
|
US20080095722A1
(en)
*
|
2004-11-12 |
2008-04-24 |
Idea Ag |
Extended Surface Aggregates in the Treatment of Skin Conditions
|
|
MX2007005866A
(es)
|
2004-11-17 |
2007-11-12 |
Amgen Inc |
Anticuerpos monoclonales totalmente humanos para il-13.
|
|
CA2592249C
(en)
|
2004-12-20 |
2014-07-29 |
Amgen Fremont Inc. |
Binding proteins specific for human matriptase
|
|
US7973140B2
(en)
|
2004-12-21 |
2011-07-05 |
Medimmune Limited |
Antibodies directed to angiopoietin-2 and uses thereof
|
|
EP1836298B1
(en)
*
|
2004-12-22 |
2012-01-18 |
Ambrx, Inc. |
COMPOSITIONS OF AMINOACYL-tRNA SYNTHETASE AND USES THEREOF
|
|
JP2008525032A
(ja)
|
2004-12-22 |
2008-07-17 |
アンブレツクス・インコーポレイテツド |
組換えヒト成長ホルモンを発現及び精製するための方法
|
|
KR101224781B1
(ko)
*
|
2004-12-22 |
2013-01-21 |
암브룩스, 인코포레이티드 |
비천연적으로 코딩된 아미노산을 포함하는 인간 성장호르몬의 조제물
|
|
CA3005835C
(en)
|
2004-12-22 |
2023-01-31 |
Ambrx, Inc. |
Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
|
|
CA2594557C
(en)
|
2004-12-22 |
2016-04-26 |
Ambrx, Inc. |
Modified human growth hormone
|
|
US20060154285A1
(en)
*
|
2004-12-29 |
2006-07-13 |
Robishaw Janet D |
Zebrafish heterotrimer G-protein gamma 2 subunit (GNG2)
|
|
AU2006208286A1
(en)
|
2005-01-26 |
2006-08-03 |
Amgen Fremont Inc. |
Antibodies against interleukin-1 beta
|
|
US20070003608A1
(en)
*
|
2005-04-08 |
2007-01-04 |
Almond Merrick R |
Compounds, compositions and methods for the treatment of viral infections and other medical disorders
|
|
WO2006110655A2
(en)
*
|
2005-04-08 |
2006-10-19 |
Chimerix, Inc. |
Compounds, compositions and methods for the treatment of poxvirus infections
|
|
US7417072B2
(en)
|
2005-05-12 |
2008-08-26 |
Wisconsin Alumni Research Foundation |
Blockade of Pin1 prevents cytokine production by activated immune cells
|
|
WO2006133088A2
(en)
*
|
2005-06-03 |
2006-12-14 |
Ambrx, Inc. |
Improved human interferon molecules and their uses
|
|
GB0511986D0
(en)
*
|
2005-06-13 |
2005-07-20 |
Imp College Innovations Ltd |
Novel compounds and their effects on feeding behaviour
|
|
CA2610839C
(en)
|
2005-06-14 |
2019-06-25 |
Amgen Inc. |
Self-buffering protein formulations
|
|
US7531166B2
(en)
|
2005-06-21 |
2009-05-12 |
Xoma Technology, Ltd. |
IL-1β binding antibodies and fragments thereof
|
|
NZ625807A
(en)
|
2005-07-18 |
2015-11-27 |
Amgen Inc |
Human anti-b7rp1 neutralizing antibodies
|
|
CN101267779A
(zh)
|
2005-07-27 |
2008-09-17 |
福罗里达大学研究基金会有限公司 |
使用热休克治疗眼睛疾病
|
|
ES2408581T3
(es)
*
|
2005-08-18 |
2013-06-21 |
Ambrx, Inc. |
Composiciones de ARNt y usos de las mismas
|
|
CA2626082C
(en)
|
2005-10-13 |
2017-04-11 |
Human Genome Sciences, Inc. |
Methods and compositions for use in treatment of patients with autoantibody positive disease
|
|
AU2006311568B2
(en)
*
|
2005-11-08 |
2010-11-11 |
Ambrx, Inc. |
Accelerants for the modification of non-natural amino acids and non-natural amino acid polypeptides
|
|
JP2009515897A
(ja)
|
2005-11-10 |
2009-04-16 |
キュラジェン コーポレイション |
Ｔ細胞の免疫グロブリンドメインおよびムチンドメイン１（ｔｉｍ−１）抗原に対する抗体を用いて卵巣癌および腎臓癌を処置する方法
|
|
PE20070684A1
(es)
|
2005-11-14 |
2007-08-06 |
Amgen Inc |
MOLECULAS QUIMERICAS DE ANTICUERPO RANKL-PTH/PTHrP
|
|
WO2007059312A2
(en)
|
2005-11-16 |
2007-05-24 |
Ambrx, Inc. |
Methods and compositions comprising non-natural amino acids
|
|
US20070213264A1
(en)
|
2005-12-02 |
2007-09-13 |
Mingdong Zhou |
Neuregulin variants and methods of screening and using thereof
|
|
WO2008024128A2
(en)
|
2005-12-05 |
2008-02-28 |
Simon Delagrave |
Loop-variant pdz domains as biotherapeutics, diagnostics and research reagents
|
|
MX2008007688A
(es)
|
2005-12-13 |
2008-09-26 |
Astrazeneca Ab |
Proteinas de enlace especificas de factores de crecimiento tipo insulina y usos de las mismas.
|
|
WO2007070659A2
(en)
*
|
2005-12-14 |
2007-06-21 |
Ambrx, Inc. |
Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
|
|
NZ569787A
(en)
|
2005-12-15 |
2011-07-29 |
Astrazeneca Ab |
Combination of angiopoietin-2 antagonist and of VEGF-A, KDR and/or FLT1 antagonist for treating cancer
|
|
KR101067525B1
(ko)
|
2005-12-22 |
2011-09-27 |
제넨테크, 인크. |
헤파린 결합 단백질의 재조합 생산
|
|
CA2841386A1
(en)
|
2005-12-30 |
2007-07-12 |
Zensun (Shanghai) Science & Technology Limited |
Extended release of neuregulin for improved cardiac function
|
|
TW200813091A
(en)
|
2006-04-10 |
2008-03-16 |
Amgen Fremont Inc |
Targeted binding agents directed to uPAR and uses thereof
|
|
WO2007130636A2
(en)
|
2006-05-03 |
2007-11-15 |
Geisinger Clinic |
Methods for diagnosing and predicting non-alcoholic steatohepatitis (nash)
|
|
WO2007136679A2
(en)
|
2006-05-17 |
2007-11-29 |
Ludwig Institute For Cancer Research |
Targeting vegf-b regulation of fatty acid transporters to modulate human diseases
|
|
WO2007143121A2
(en)
|
2006-06-01 |
2007-12-13 |
President And Fellows Of Harvard College |
Purification of a bivalently active antibody using a non-chromatographic method
|
|
GB0611405D0
(en)
|
2006-06-09 |
2006-07-19 |
Univ Belfast |
FKBP-L: A novel inhibitor of angiogenesis
|
|
EP2412383A1
(en)
|
2006-07-28 |
2012-02-01 |
Children's Memorial Hospital |
Methods of inhibiting tumor cell aggressiveness using the microenvironment of human embryonic stem cells
|
|
CL2007002225A1
(es)
|
2006-08-03 |
2008-04-18 |
Astrazeneca Ab |
Agente de union especifico para un receptor del factor de crecimiento derivado de plaquetas (pdgfr-alfa); molecula de acido nucleico que lo codifica; vector y celula huesped que la comprenden; conjugado que comprende al agente; y uso del agente de un
|
|
WO2008019368A2
(en)
|
2006-08-07 |
2008-02-14 |
Teva Biopharmaceuticals Usa, Inc. |
Albumin-insulin fusion proteins
|
|
CN106008699A
(zh)
*
|
2006-09-08 |
2016-10-12 |
Ambrx公司 |
经修饰的人类血浆多肽或Fc骨架和其用途
|
|
SG174788A1
(en)
*
|
2006-09-08 |
2011-10-28 |
Ambrx Inc |
Suppressor trna transcription in vertebrate cells
|
|
PT2061878E
(pt)
*
|
2006-09-08 |
2014-04-22 |
Ambrx Inc |
Supressor híbrido arnt para células de vertebrados
|
|
US7833527B2
(en)
|
2006-10-02 |
2010-11-16 |
Amgen Inc. |
Methods of treating psoriasis using IL-17 Receptor A antibodies
|
|
CN101855241B
(zh)
|
2006-12-08 |
2013-11-06 |
莱克康制药公司 |
针对angptl3的单克隆抗体
|
|
TWI428346B
(zh)
|
2006-12-13 |
2014-03-01 |
Imp Innovations Ltd |
新穎化合物及其等對進食行為影響
|
|
EP2094306A2
(en)
|
2006-12-20 |
2009-09-02 |
XOMA Technology Ltd. |
Treatment of il-1-beta related diseases
|
|
US10155038B2
(en)
|
2007-02-02 |
2018-12-18 |
Yale University |
Cells prepared by transient transfection and methods of use thereof
|
|
US8859229B2
(en)
*
|
2007-02-02 |
2014-10-14 |
Yale University |
Transient transfection with RNA
|
|
US9249423B2
(en)
*
|
2007-02-02 |
2016-02-02 |
Yale University |
Method of de-differentiating and re-differentiating somatic cells using RNA
|
|
US7947646B2
(en)
|
2007-03-06 |
2011-05-24 |
Amgen Inc. |
Variant activin receptor polypeptides
|
|
US8501678B2
(en)
|
2007-03-06 |
2013-08-06 |
Atara Biotherapeutics, Inc. |
Variant activin receptor polypeptides and uses thereof
|
|
KR101808787B1
(ko)
|
2007-03-30 |
2017-12-13 |
암브룩스, 인코포레이티드 |
변형된 ｆｇｆ-21 폴리펩티드 및 그 용도
|
|
JP2010525821A
(ja)
*
|
2007-05-02 |
2010-07-29 |
アンブルックス，インコーポレイテッド |
修飾ＩＦＮβポリペプチドおよびこれらの使用
|
|
JP5443979B2
(ja)
|
2007-05-11 |
2014-03-19 |
備前化成株式会社 |
新規のロイコトリエン受容体アンタゴニスト
|
|
MX2009013765A
(es)
|
2007-06-27 |
2010-02-01 |
Auckland Uniservices Ltd |
Polipeptidos y polinucleotidos para artemina y ligandos relacionados, y metodos de uso de los mismos.
|
|
JP5718640B2
(ja)
|
2007-08-21 |
2015-05-13 |
アムジエン・インコーポレーテツド |
ヒトｃ−ｆｍｓ抗原結合性タンパク質
|
|
JOP20080381B1
(ar)
|
2007-08-23 |
2023-03-28 |
Amgen Inc |
بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9)
|
|
EP2615113A3
(en)
|
2007-08-23 |
2013-11-13 |
Amgen Inc. |
Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (PCSK9)
|
|
US7982016B2
(en)
|
2007-09-10 |
2011-07-19 |
Amgen Inc. |
Antigen binding proteins capable of binding thymic stromal lymphopoietin
|
|
US20090156488A1
(en)
|
2007-09-12 |
2009-06-18 |
Zensun (Shanghai) Science & Technology Limited |
Use of neuregulin for organ preservation
|
|
TW200918553A
(en)
|
2007-09-18 |
2009-05-01 |
Amgen Inc |
Human GM-CSF antigen binding proteins
|
|
EP2040075A1
(en)
|
2007-09-24 |
2009-03-25 |
Julius-Maximilians-Universität Würzburg |
Compounds and markers for surface-enhanced raman scattering
|
|
US8828382B2
(en)
|
2007-09-26 |
2014-09-09 |
U3 Pharma Gmbh |
Heparin-binding epidermal growth factor-like growth factor binding proteins
|
|
KR101656107B1
(ko)
*
|
2007-11-20 |
2016-09-08 |
암브룩스, 인코포레이티드 |
변형된 인슐린 폴리펩티드 및 이의 용도
|
|
RU2018100129A
(ru)
|
2007-12-20 |
2019-02-20 |
Ксома (Сша) Ллс |
Способы лечения подагры
|
|
CN105055432A
(zh)
*
|
2008-01-25 |
2015-11-18 |
奇默里克斯公司 |
治疗病毒感染的方法
|
|
NZ620606A
(en)
|
2008-02-08 |
2015-08-28 |
Ambrx Inc |
Modified leptin polypeptides and their uses
|
|
JO2913B1
(en)
|
2008-02-20 |
2015-09-15 |
امجين إنك, |
Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
|
|
FI20080326A0
(fi)
|
2008-04-30 |
2008-04-30 |
Licentia Oy |
Neurotroofinen tekijä MANF ja sen käytöt
|
|
JOP20190083A1
(ar)
|
2008-06-04 |
2017-06-16 |
Amgen Inc |
بولي ببتيدات اندماجية طافرة لـfgf21 واستخداماتها
|
|
PL2684873T3
(pl)
|
2008-06-09 |
2019-07-31 |
Ludwig-Maximilians-Universität München |
Leki do hamowania agregacji białek związanych z chorobami związanymi z agregacją białka i/lub chorobami neurodegeneracyjnymi
|
|
CA2729012A1
(en)
|
2008-06-27 |
2009-12-30 |
Amgen Inc. |
Ang-2 inhibition to treat multiple sclerosis
|
|
CA2729851C
(en)
|
2008-07-23 |
2019-01-15 |
Ambrx, Inc. |
Modified bovine g-csf polypeptides and their uses
|
|
EP3629022A1
(en)
|
2008-07-25 |
2020-04-01 |
Richard W. Wagner |
Protein screening methods
|
|
WO2010030813A2
(en)
|
2008-09-10 |
2010-03-18 |
Genentech, Inc. |
Methods for inhibiting ocular angiogenesis
|
|
RU2581962C2
(ru)
|
2008-09-19 |
2016-04-20 |
Медиммун Ллк |
Нацеленные средства связывания, направленные на dll4, и их применение
|
|
WO2010034837A1
(en)
*
|
2008-09-26 |
2010-04-01 |
Phares Pharmaceutical Research N.V. |
Method of solubilising biologically active compounds
|
|
MX348657B
(es)
|
2008-09-26 |
2017-06-21 |
Ambrx Inc |
Microorganismos y vacunas dependientes de replicacion de aminoacidos no naturales.
|
|
JP5694171B2
(ja)
|
2008-09-26 |
2015-04-01 |
アンブルックス, インコーポレイテッドAmbrx, Inc. |
修飾されている動物のエリスロポエチンポリペプチドおよびそれらの使用
|
|
CN102625811B
(zh)
|
2008-10-10 |
2016-09-21 |
安姆根有限公司 |
Fgf21突变体及其用途
|
|
WO2010062383A2
(en)
|
2008-11-26 |
2010-06-03 |
Amgen Inc. |
Stabilized receptor polypeptides and uses thereof
|
|
WO2010070136A2
(en)
|
2008-12-19 |
2010-06-24 |
Centre de Recherche Public de la Santé |
Novel caviidae allergens and uses thereof
|
|
EP2367564A1
(en)
|
2008-12-22 |
2011-09-28 |
Universität Regensburg |
Norrin in the treatment of diseases associated with an increased tgf-beta activity
|
|
JO3382B1
(ar)
|
2008-12-23 |
2019-03-13 |
Amgen Inc |
أجسام مضادة ترتبط مع مستقبل cgrp بشري
|
|
CA2748158A1
(en)
|
2008-12-23 |
2010-07-01 |
Astrazeneca Ab |
Targeted binding agents directed to .alpha.5.beta.1 and uses thereof
|
|
KR101040396B1
(ko)
|
2009-01-20 |
2011-06-09 |
한올바이오파마주식회사 |
변형된 인간 트롬보포이에틴 폴리펩타이드 절편 및 그의 제조방법
|
|
EP2396035A4
(en)
|
2009-02-12 |
2012-09-12 |
Human Genome Sciences Inc |
USE OF ANTAGONISTS OF PROTEIN STIMULATING LYMPHOCYTES B TO PROMOTE GRAFT TOLERANCE
|
|
CA2751831A1
(en)
|
2009-02-13 |
2010-08-19 |
Novartis Ag |
Nucleic acid molecule of a biosynthetic cluster encoding non ribosomal peptide synthases and uses thereof
|
|
EP2427207B1
(en)
|
2009-05-05 |
2017-08-16 |
Amgen, Inc |
Fgf21 mutants and uses thereof
|
|
AU2010246108B2
(en)
|
2009-05-05 |
2014-10-23 |
Amgen Inc. |
FGF21 mutants and uses thereof
|
|
EP2260857A1
(en)
|
2009-06-11 |
2010-12-15 |
Alfact Innovation |
Novel applications of HIP/PAP or derivatives thereof
|
|
IN2012DN00352A
(da)
|
2009-06-16 |
2015-08-21 |
Bikam Pharmaceuticals Inc |
|
|
AU2010262927A1
(en)
|
2009-06-17 |
2012-01-19 |
Amgen Inc. |
Chimeric FGF19 polypeptides and uses thereof
|
|
US8614200B2
(en)
|
2009-07-21 |
2013-12-24 |
Chimerix, Inc. |
Compounds, compositions and methods for treating ocular conditions
|
|
EP2305285A1
(en)
|
2009-09-29 |
2011-04-06 |
Julius-Maximilians-Universität Würzburg |
Means and methods for treating ischemic conditions
|
|
EP2305810A1
(en)
|
2009-10-02 |
2011-04-06 |
Technische Universität München |
miRNAs in the treatment of fibrosis
|
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
|
WO2011046457A1
(en)
|
2009-10-16 |
2011-04-21 |
Auckland Uniservices Limited |
Anti-neoplastic uses of artemin antagonists
|
|
WO2011056650A2
(en)
|
2009-10-27 |
2011-05-12 |
Michael Zasloff |
Methods and compositions for treating and preventing viral infections
|
|
SG10201406801XA
(en)
|
2009-11-02 |
2014-11-27 |
Univ Washington |
Therapeutic nuclease compositions and methods
|
|
US20130116182A1
(en)
|
2009-11-13 |
2013-05-09 |
Kathleen Pratt |
Factor VIII B Cell Epitope Variants Having Reduced Immunogenicity
|
|
CA2992770A1
(en)
|
2009-11-24 |
2011-06-03 |
Medimmune Limited |
Targeted binding agents against b7-h1
|
|
US8623416B2
(en)
|
2009-11-25 |
2014-01-07 |
Michael Zasloff |
Formulations comprising aminosterols
|
|
US8491927B2
(en)
|
2009-12-02 |
2013-07-23 |
Nimble Epitech, Llc |
Pharmaceutical composition containing a hypomethylating agent and a histone deacetylase inhibitor
|
|
UA109888C2
(uk)
|
2009-12-07 |
2015-10-26 |
|
ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
|
|
MX2012006980A
(es)
|
2009-12-21 |
2012-07-17 |
Ambrx Inc |
Polipeptidos de somatotropina porcina modificados y sus usos.
|
|
JP2013515080A
(ja)
|
2009-12-21 |
2013-05-02 |
アンブルックス，インコーポレイテッド |
修飾されているウシのソマトトロピンポリペプチドおよびそれらの使用
|
|
EP2525792A1
(en)
|
2010-01-19 |
2012-11-28 |
Medizinische Universität Wien |
Pharmaceutical compositions comprising lignans and their derivatives for the medical management of angiogenesis and hypovascularity
|
|
AU2011210825B2
(en)
|
2010-01-27 |
2017-02-02 |
Children's Medical Center Corporation |
Pro-angiogenic fragments of prominin-1 and uses thereof
|
|
EP2533859B1
(en)
|
2010-02-10 |
2016-04-06 |
Nayacure Therapeutics Ltd |
Pharmaceutical compositions for the treatment and prevention of cancer
|
|
HUE032860T2
(en)
|
2010-02-12 |
2017-11-28 |
Chimerix Inc |
A method for treating a virus infection
|
|
WO2011130417A2
(en)
|
2010-04-15 |
2011-10-20 |
Amgen Inc. |
HUMAN FGF RECEPTOR AND β-KLOTHO BINDING PROTEINS
|
|
US20130116304A1
(en)
|
2010-04-19 |
2013-05-09 |
Ernst R. Werner |
Tmem195 encodes for tetrahydrobiopterin-dependent alkylglycerol monooxygenase activity
|
|
EP2563367A4
(en)
|
2010-04-26 |
2013-12-04 |
Chimerix Inc |
METHODS OF TREATING RETROVIRAL INFECTIONS AND ASSOCIATED DOSAGE REGIMES
|
|
EP2566964B1
(en)
|
2010-05-07 |
2016-10-19 |
Centre National De La Recherche Scientifique |
Ucp1 (thermogenin) - inducing agents for use in the treatment of a disorder of the energy homeostasis
|
|
EP3190187A1
(en)
|
2010-05-21 |
2017-07-12 |
Peptimed, Inc. |
Reagents and methods for treating cancer
|
|
BR112012032008B1
(pt)
|
2010-06-14 |
2020-05-26 |
Lykera Biomed Sa |
Anticorpos s100a4, linhagem celular de hibridoma, composição farmacêutica, conjugado, método e kit para diagnosticar câncer ou uma doença associada à inflamação
|
|
CN103038253A
(zh)
|
2010-06-18 |
2013-04-10 |
西伯尔科学有限公司 |
作为用来稳定生物屏障的活性剂的肽
|
|
US8735539B2
(en)
|
2010-08-17 |
2014-05-27 |
Ambrx, Inc. |
Relaxin polypeptides comprising non-naturally encoded amino acids
|
|
US9567386B2
(en)
|
2010-08-17 |
2017-02-14 |
Ambrx, Inc. |
Therapeutic uses of modified relaxin polypeptides
|
|
TWI480288B
(zh)
|
2010-09-23 |
2015-04-11 |
Lilly Co Eli |
牛顆粒細胞群落刺激因子及其變體之調配物
|
|
EP3219725B1
(en)
|
2010-10-27 |
2020-12-16 |
Amgen Inc. |
Dkk1 antibodies and methods of use
|
|
SG190088A1
(en)
|
2010-11-01 |
2013-06-28 |
Peptimed Inc |
Compositions of a peptide targeting system for treating cancer
|
|
US9023791B2
(en)
|
2010-11-19 |
2015-05-05 |
Novartis Ag |
Fibroblast growth factor 21 mutations
|
|
RU2013123793A
(ru)
|
2010-11-24 |
2014-12-27 |
Лексикон Фармасьютикалз, Инк. |
Антитела, связывающиеся с notum пектинацетилэстеразой
|
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
|
DK2665746T3
(en)
|
2011-01-17 |
2021-02-01 |
Lykera Biomed S A |
Antibodies against the s100p protein for the treatment and diagnosis of cancer
|
|
SG10201600531TA
(en)
|
2011-01-24 |
2016-02-26 |
Univ Singapore |
Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins
|
|
LT2667715T
(lt)
|
2011-01-27 |
2017-11-10 |
Neuren Pharmaceuticals Limited |
Autizmo spektro susirgimų gydymas, naudojant glicil-l-2-metilprolil-l-glutamo rūgštį
|
|
CN103649118A
(zh)
|
2011-03-01 |
2014-03-19 |
安进公司 |
双特异性结合剂
|
|
CN103533928A
(zh)
|
2011-03-10 |
2014-01-22 |
霍夫曼-拉罗奇有限公司 |
对具有改变的血管屏障功能的病症的治疗
|
|
CA2831957A1
(en)
|
2011-04-07 |
2012-10-11 |
Amgen Inc. |
Novel egfr binding proteins
|
|
CA2832581C
(en)
|
2011-04-08 |
2022-08-23 |
Yumei Xiong |
Method of treating or ameliorating metabolic disorders using growth differentiation factor 15 (gdf-15)
|
|
AU2012249360B2
(en)
|
2011-04-29 |
2015-12-24 |
University Of Washington |
Therapeutic nuclease compositions and methods
|
|
US20140189893A1
(en)
|
2011-05-10 |
2014-07-03 |
Amgen Inc. |
Method of identifying compounds that specifically modulate the interaction of fgfr1 and beta klotho
|
|
JOP20200043A1
(ar)
|
2011-05-10 |
2017-06-16 |
Amgen Inc |
طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول
|
|
US9574002B2
(en)
|
2011-06-06 |
2017-02-21 |
Amgen Inc. |
Human antigen binding proteins that bind to a complex comprising β-Klotho and an FGF receptor
|
|
EP2720539B1
(en)
|
2011-06-14 |
2018-10-24 |
Bikam Pharmaceuticals, Inc. |
Opsin-binding ligands, compositions and methods of use
|
|
JP2014520123A
(ja)
|
2011-06-17 |
2014-08-21 |
アムジエン・インコーポレーテツド |
Ｃｌｅｃ−２を使用して代謝性障害を治療または改善させる方法
|
|
US20140234330A1
(en)
|
2011-07-22 |
2014-08-21 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
|
WO2013017656A1
(en)
|
2011-08-02 |
2013-02-07 |
Medizinische Universität Wien |
Antagonists of ribonucleases for treating obesity
|
|
US9328386B2
(en)
|
2011-08-16 |
2016-05-03 |
Evotec (München) Gmbh |
Markers for susceptibility to an inhibitor of an Src-family kinase
|
|
US9605083B2
(en)
|
2011-08-16 |
2017-03-28 |
Emory University |
JAML specific binding agents, antibodies, and uses related thereto
|
|
JP2014526441A
(ja)
|
2011-08-31 |
2014-10-06 |
アムジエン・インコーポレーテツド |
１型糖尿病の治療における使用のためのｆｇｆ２１
|
|
AU2012312274B2
(en)
|
2011-09-22 |
2017-11-16 |
Amgen Inc. |
CD27L antigen binding proteins
|
|
UY34347A
(es)
|
2011-09-26 |
2013-04-30 |
Novartis Ag |
Proteínas de función dual para tratar trastornos metabólicos
|
|
UY34346A
(es)
|
2011-09-26 |
2013-04-30 |
Novartis Ag |
Proteínas de fusión para tratar trastornos metabólicos
|
|
WO2013053076A1
(en)
|
2011-10-10 |
2013-04-18 |
Zensun （Shanghai）Science & Technology Limited |
Compositions and methods for treating heart failure
|
|
WO2013056255A1
(en)
|
2011-10-14 |
2013-04-18 |
The Board Of Trustees Of The University Of Illinois |
Methods and compositions for inhibiting tumor cell proliferation
|
|
US8906860B2
(en)
|
2011-10-14 |
2014-12-09 |
The Board Of Trustees Of The University Of Illinois |
Methods and compositions inhibiting tumor cell proliferation
|
|
US20140314667A1
(en)
|
2011-11-16 |
2014-10-23 |
Amgen Inc. |
Methods of treating epidermal growth factor deletion mutant viii related disorders
|
|
GR1007832B
(el)
|
2011-11-21 |
2013-02-14 |
Ιδρυμα Ιατροβιολογικων Ερευνων Ακαδημιας Αθηνων, |
Αδρανοποιητες της ακτιβινης και χρηση τους για την θεραπεια ασθενειων που σχετιζονται με παρεκκλινουσα ενεργοποιηση της "αμυντικης αποκρισης του ξενιστη"
|
|
BR112014012997A2
(pt)
|
2011-11-30 |
2017-06-13 |
Bikam Pharmaceuticals Inc |
ligantes que se ligam à opsina, composições e métodos de uso
|
|
EP2601941A1
(en)
|
2011-12-06 |
2013-06-12 |
Ludwig-Maximilians-Universität München |
Beta-O/S/N fatty acid based compounds as antibacterial and antiprotozoal agents
|
|
EP2788384B1
(en)
|
2011-12-08 |
2017-08-09 |
Amgen Inc. |
Agonistic human lcat antigen binding proteins and their use in therapy
|
|
EP2788500A1
(en)
|
2011-12-09 |
2014-10-15 |
F.Hoffmann-La Roche Ag |
Identification of non-responders to her2 inhibitors
|
|
JP6320300B2
(ja)
|
2011-12-19 |
2018-05-09 |
ゾーマ （ユーエス） リミテッド ライアビリティ カンパニー |
座瘡を治療するための方法
|
|
SG11201403367YA
(en)
|
2011-12-19 |
2014-07-30 |
Amgen Inc |
Variant activin receptor polypeptides, alone or in combination with chemotherapy, and uses thereof
|
|
JP6684490B2
(ja)
|
2012-01-09 |
2020-04-22 |
ザ・スクリップス・リサーチ・インスティテュート |
超長相補性決定領域及びその使用
|
|
CA2862979A1
(en)
|
2012-01-09 |
2013-07-18 |
The Scripps Research Institute |
Humanized antibodies with ultralong cdr3s
|
|
US9714276B2
(en)
|
2012-01-26 |
2017-07-25 |
Amgen Inc. |
Growth differentiation factor 15 (GDF-15) polypeptides
|
|
EP2626066A1
(en)
|
2012-02-10 |
2013-08-14 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Combination therapy comprising selective VEGFR-2 inhibitors and MEK inhibitors
|
|
EA039663B1
(ru)
|
2012-05-03 |
2022-02-24 |
Амген Инк. |
Применение антитела против pcsk9 для снижения сывороточного холестерина лпнп и лечения связанных с холестерином расстройств
|
|
ES2755104T3
(es)
|
2012-05-17 |
2020-04-21 |
Ra Pharmaceuticals Inc |
Inhibidores peptídicos y peptidomiméticos
|
|
AR091069A1
(es)
|
2012-05-18 |
2014-12-30 |
Amgen Inc |
Proteinas de union a antigeno dirigidas contra el receptor st2
|
|
EP2666775A1
(en)
|
2012-05-21 |
2013-11-27 |
Domain Therapeutics |
Substituted pyrazoloquinazolinones and pyrroloquinazolinones as allosteric modulators of group II metabotropic glutamate receptors
|
|
WO2013177187A2
(en)
|
2012-05-22 |
2013-11-28 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with extended-pk il-2 and therapeutic agents
|
|
AU2013285537B2
(en)
|
2012-07-02 |
2017-10-12 |
Medizinische Universitat Wien |
Complement split product C4d for the treatment of inflammatory conditions
|
|
EP2687225A1
(en)
|
2012-07-19 |
2014-01-22 |
Alfact Innovation |
HIP/PAP protein and derivatives thereof for use in treating cancer
|
|
EP2695950A1
(en)
|
2012-08-10 |
2014-02-12 |
Blackfield AG |
Markers for responsiveness to an inhibitor of the fibroblast growth factor receptor
|
|
JP2015526471A
(ja)
|
2012-08-21 |
2015-09-10 |
ジェネシス リサーチ インスティチュート |
アントラサイクリン誘発性心毒性を治療または予防するための組成物および方法
|
|
US9309318B2
(en)
|
2012-10-17 |
2016-04-12 |
Amgen, Inc. |
Compositions relating to anti-IL-21 receptor antibodies
|
|
UY35148A
(es)
|
2012-11-21 |
2014-05-30 |
Amgen Inc |
Immunoglobulinas heterodiméricas
|
|
KR102291355B1
(ko)
|
2012-11-30 |
2021-08-19 |
에프. 호프만-라 로슈 아게 |
Pd-l1 억제제 공동치료를 필요로 하는 환자의 식별방법
|
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Ｂｃｍａ抗原結合蛋白質
|
|
WO2014114801A1
(en)
|
2013-01-25 |
2014-07-31 |
Amgen Inc. |
Antibodies targeting cdh19 for melanoma
|
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
|
EP2951205B1
(en)
|
2013-02-01 |
2021-08-11 |
Santa Maria Biotherapeutics, Inc. |
Anti-activin-a compounds for the treatment of ovarian cancer
|
|
US9458246B2
(en)
|
2013-03-13 |
2016-10-04 |
Amgen Inc. |
Proteins specific for BAFF and B7RP1
|
|
JOP20140087B1
(ar)
|
2013-03-13 |
2021-08-17 |
Amgen Inc |
بروتينات مخصصة ل baff و b7rp1 وإستخداماتها
|
|
CA2904337A1
(en)
|
2013-03-14 |
2014-10-02 |
Amgen Inc. |
Chrdl-1 antigen binding proteins and methods of treatment
|
|
US9580486B2
(en)
|
2013-03-14 |
2017-02-28 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of T-regulatory cells
|
|
TW201902931A
(zh)
|
2013-03-15 |
2019-01-16 |
美商安美基公司 |
人類pac1抗體
|
|
TW201525001A
(zh)
|
2013-03-15 |
2015-07-01 |
Amgen Res Munich Gmbh |
包含ｎ－端ａｂｐ之單鏈結合分子
|
|
EP2970446A1
(en)
|
2013-03-15 |
2016-01-20 |
Amgen Research (Munich) GmbH |
Antibody constructs for influenza m2 and cd3
|
|
US9708375B2
(en)
|
2013-03-15 |
2017-07-18 |
Amgen Inc. |
Inhibitory polypeptides specific to WNT inhibitors
|
|
EP2970483A2
(en)
|
2013-03-15 |
2016-01-20 |
Amgen Inc. |
Methods and compositions relating to anti-ccr7 antigen binding proteins
|
|
WO2014151962A1
(en)
|
2013-03-15 |
2014-09-25 |
Amgen Inc. |
Method of treating metabolic disorders using pla2g12a polypeptides and pla2g12a mutant polypeptides
|
|
WO2014144553A1
(en)
|
2013-03-15 |
2014-09-18 |
Amgen Inc. |
Secreted frizzle-related protein 5 (sfrp5) binding proteins and methods of treatment
|
|
DK2984108T3
(en)
|
2013-04-09 |
2017-09-18 |
Lykera Biomed S A |
Anti-s100a7 antibodies for the treatment and diagnosis of cancer
|
|
EP2801370A1
(en)
|
2013-05-07 |
2014-11-12 |
Fundació Privada Institut d'Investigació Oncològica de Vall Hebron |
Methods and compositions for the treatment of cancer
|
|
EP2999797B1
(en)
|
2013-05-21 |
2018-07-04 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Isoforms of gata6 and nkx2-1 as markers for diagnosis and therapy of cancer and as targets for anti-cancer therapy
|
|
ES2743617T3
(es)
|
2013-05-22 |
2020-02-20 |
Zensun Shanghai Science & Tech Co Ltd |
Liberación prolongada de neuregulina para tratar la insuficiencia cardíaca
|
|
WO2014191630A2
(en)
|
2013-05-28 |
2014-12-04 |
Helsingin Yliopisto |
Non-human animal model encoding a non-functional manf gene
|
|
CN107513105B
(zh)
|
2013-05-30 |
2019-08-16 |
基尼克萨制药有限公司 |
制瘤素m受体抗原结合蛋白
|
|
EP2810648A1
(en)
|
2013-06-04 |
2014-12-10 |
Daniel Rauh |
Targeting domain-domain interaction for the identification of kinase modulators
|
|
EP2835135A3
(en)
|
2013-06-19 |
2015-06-24 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin |
Means and methods for treating pseudomonas infection
|
|
EP3013422A1
(en)
|
2013-06-28 |
2016-05-04 |
Amgen Inc. |
Methods for treating homozygous familial hypercholesterolemia
|
|
WO2014207213A1
(en)
|
2013-06-28 |
2014-12-31 |
Medizinische Universität Innsbruck |
Novel inhibitors of protein kinase c epsilon signaling
|
|
EP3022224A2
(en)
|
2013-07-18 |
2016-05-25 |
Fabrus, Inc. |
Antibodies with ultralong complementarity determining regions
|
|
CN105814074B
(zh)
|
2013-07-18 |
2020-04-21 |
图鲁斯生物科学有限责任公司 |
具有超长互补决定区的人源化抗体
|
|
DK3027642T3
(da)
|
2013-07-31 |
2020-11-02 |
Amgen Inc |
Vækstdifferentieringsfaktor 15 (gdf-15)-konstruktioner
|
|
WO2015022326A1
(en)
|
2013-08-12 |
2015-02-19 |
Xiber Science Gmbh |
Peptides as active agents for treating primary graft dysfunction
|
|
TW201605896A
(zh)
|
2013-08-30 |
2016-02-16 |
安美基股份有限公司 |
Gitr抗原結合蛋白
|
|
AU2014318017B2
(en)
|
2013-09-05 |
2020-02-06 |
Amgen Inc. |
Fc-containing molecules exhibiting predictable, consistent, and reproducible glycoform profiles
|
|
CA2924109A1
(en)
|
2013-09-13 |
2015-03-19 |
The California Institute For Biomedical Research |
Modified therapeutic agents and compositions thereof
|
|
AR097648A1
(es)
|
2013-09-13 |
2016-04-06 |
Amgen Inc |
Combinación de factores epigenéticos y compuestos biespecíficos que tienen como diana cd33 y cd3 en el tratamiento de leucemia mieloide
|
|
PT2808338E
(pt)
|
2013-09-16 |
2016-06-15 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Calreticulina mutante para o diagnóstico de malignidades mieloides
|
|
WO2015048331A1
(en)
|
2013-09-25 |
2015-04-02 |
Cornell University |
Compounds for inducing anti-tumor immunity and methods thereof
|
|
JP6637415B2
(ja)
|
2013-10-15 |
2020-01-29 |
ザ スクリプス リサーチ インスティテュート |
キメラ抗原受容体ｔ細胞スイッチおよびその使用
|
|
CN105829349B
(zh)
|
2013-10-15 |
2023-02-03 |
斯克利普斯研究所 |
肽嵌合抗原受体t细胞开关和其用途
|
|
EP3057605A1
(en)
|
2013-10-18 |
2016-08-24 |
Novartis AG |
Methods of treating diabetes and related disorders
|
|
ES2759252T3
(es)
|
2013-10-31 |
2020-05-08 |
Resolve Therapeutics Llc |
Fusiones y métodos terapéuticos de nucleasa-albúmina
|
|
GB201319374D0
(en)
|
2013-11-01 |
2013-12-18 |
Univ Nottingham |
Glycans as functional cancer targets abd antibodies thereto
|
|
KR102455171B1
(ko)
|
2013-12-18 |
2022-10-14 |
더 스크립스 리서치 인스티튜트 |
변형된 치료제, 스테이플드 펩티드 지질 접합체, 및 이의 조성물
|
|
CN103965357B
(zh)
|
2013-12-31 |
2016-08-17 |
嘉和生物药业有限公司 |
一种抗人rankl抗体
|
|
WO2015110930A1
(en)
|
2014-01-24 |
2015-07-30 |
Pfizer Inc. |
Modified interleukin 21 receptor proteins
|
|
EP3104873B1
(en)
|
2014-02-13 |
2019-09-04 |
Technische Universität München |
Fgf-8 for use in treating diseases or disorders of energy homeostasis
|
|
CA3177696A1
(en)
|
2014-02-20 |
2015-08-27 |
Allergan, Inc. |
Complement component c5 antibodies
|
|
CN110724691A
(zh)
|
2014-02-27 |
2020-01-24 |
阿勒根公司 |
补体因子Bb抗体
|
|
US10507227B2
(en)
|
2014-04-15 |
2019-12-17 |
The Hospital For Sick Children |
Cationic antimicrobial peptides
|
|
WO2015173398A1
(en)
|
2014-05-15 |
2015-11-19 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Antagonists of slc38a9 and their use in therapy
|
|
US20170119851A1
(en)
|
2014-05-19 |
2017-05-04 |
Novartis Ag |
Methods of treating anorexia
|
|
EP2947460A1
(en)
|
2014-05-22 |
2015-11-25 |
Medizinische Universität Wien |
Personalized therapy of inflammation-associated cancer using methods of assessing the susceptibility of a subject to the treatment with EGFR inhibitors/antagonists
|
|
JP2017519009A
(ja)
|
2014-06-13 |
2017-07-13 |
サンタ マリア バイオセラピューティクス インコーポレイテッド |
製剤化された受容体ポリペプチドおよび関連する方法
|
|
WO2016016859A1
(en)
|
2014-07-31 |
2016-02-04 |
Amgen Research (Munich) Gmbh |
Optimized cross-species specific bispecific single chain antibody constructs
|
|
UY36245A
(es)
|
2014-07-31 |
2016-01-29 |
Amgen Res Munich Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
|
US9872908B2
(en)
*
|
2014-08-09 |
2018-01-23 |
Avanti Polar Lipids, Inc. |
Oral composition for delivery of drugs and other substances
|
|
US20170216403A1
(en)
|
2014-08-12 |
2017-08-03 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2, a therapeutic antibody, and an immune checkpoint blocker
|
|
US10166273B2
(en)
|
2014-08-12 |
2019-01-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
Synergistic tumor treatment with antibodies targeting PD-1, PD-L1 or CTLA4 and integrin-binding-Fc-fusion protein
|
|
CN107109410B
(zh)
|
2014-08-22 |
2021-11-02 |
奥克兰联合服务有限公司 |
通道调节剂
|
|
SG11201701402QA
(en)
|
2014-08-27 |
2017-03-30 |
Peptimed Inc |
Anti-tumor compositions and methods
|
|
WO2016040767A2
(en)
|
2014-09-12 |
2016-03-17 |
Amgen Inc. |
Chrdl-1 epitopes and antibodies
|
|
EP3000814A1
(en)
|
2014-09-26 |
2016-03-30 |
Domain Therapeutics |
Substituted pyrazoloquinazolinones and pyrroloquinazolinones as allosteric modulators of group II metabotropic glutamate receptors
|
|
CN114853868A
(zh)
|
2014-10-24 |
2022-08-05 |
百时美施贵宝公司 |
修饰的fgf-21多肽及其用途
|
|
WO2016069889A1
(en)
|
2014-10-31 |
2016-05-06 |
Resolve Therapeutics, Llc |
Therapeutic nuclease-transferrin fusions and methods
|
|
WO2016079321A1
(en)
|
2014-11-20 |
2016-05-26 |
Cemm Forschungszentrum Für Molekulare Medizin Gmbh |
Antagonists of setdb2 for use in the therapy of infectious diseases
|
|
EP3085709B1
(en)
|
2014-12-28 |
2019-08-21 |
Genor Biopharma Co., Ltd |
Humanized anti-human rankl antibody, pharmaceutical composition and use thereof
|
|
JP7264592B2
(ja)
|
2015-01-26 |
2023-04-25 |
ザ ユニバーシティー オブ シカゴ |
ＩＬ１３Ｒα２結合剤及び癌治療におけるその使用
|
|
CN107835820B
(zh)
|
2015-01-26 |
2021-10-15 |
芝加哥大学 |
识别癌症特异性IL13Rα2的CAR T细胞
|
|
WO2016135138A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Oxoquinoline derivatives as mth1 inhibitors for the therapy of cancer
|
|
WO2016135137A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Substituted 4-(phenylamino)quinoline derivatives as mth1 inhibitors for the therapy of cancer
|
|
WO2016135139A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
2,3-dihydrocyclopenta[b]quinoline derivatives as mth1 inhibitors for the therapy of cancer
|
|
EP3262064A1
(en)
|
2015-02-23 |
2018-01-03 |
Seagull Therapeutics SAS |
Non-natural semaphorins 3 and their medical use
|
|
WO2016135140A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
4-aminoquinazoline derivatives as mth1 inhibitors for the therapy of cancer
|
|
WO2016154621A1
(en)
|
2015-03-26 |
2016-09-29 |
The California Institute For Biomedical Research |
SWITCHABLE NON-scFv CHIMERIC RECEPTORS, SWITCHES, AND USES THEREOF
|
|
WO2016164937A2
(en)
|
2015-04-10 |
2016-10-13 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
|
CR20170510A
(es)
|
2015-04-10 |
2018-02-26 |
Amgen Inc |
Muteínas de interuquina 2 para la expansión de células t regulatorias
|
|
US11091546B2
(en)
|
2015-04-15 |
2021-08-17 |
The Scripps Research Institute |
Optimized PNE-based chimeric receptor T cell switches and uses thereof
|
|
JP6907124B2
(ja)
|
2015-04-17 |
2021-07-21 |
アムゲン リサーチ （ミュンヘン） ゲーエムベーハーＡＭＧＥＮ Ｒｅｓｅａｒｃｈ（Ｍｕｎｉｃｈ）ＧｍｂＨ |
Ｃｄｈ３及びｃｄ３に対する二重特異性抗体構築物
|
|
US10864190B2
(en)
|
2015-04-22 |
2020-12-15 |
CeMM—FORSCHUNGSZENTRUM FÜR MOLEKULARE MEDIZIN GmbH |
Combination of an antiandrogen with a vitamin K antagonist or with a gamma-glutamyl carboxylase inhibitor for the therapy of androgen receptor positive cancer
|
|
US20160361380A1
(en)
|
2015-06-12 |
2016-12-15 |
Nymox Corporation |
Combination compositions for treating disorders requiring removal or destruction of unwanted cellular proliferations
|
|
CN107921098A
(zh)
|
2015-06-17 |
2018-04-17 |
加州生物医学研究所 |
修饰的治疗剂及其组合物
|
|
WO2017007955A1
(en)
|
2015-07-07 |
2017-01-12 |
The Research Foundation For The State University Of New York |
Use of amine carboxyboranes as therapeutic delivery of carbon monoxide and as general drug delivery system in the presence of reactive oxygen species
|
|
TW202346349A
(zh)
|
2015-07-31 |
2023-12-01 |
德商安美基研究（慕尼黑）公司 |
Dll3及cd3抗體構築體
|
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究（慕尼黑）公司 |
Ｆｌｔ３及ｃｄ３抗體構築體
|
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究（慕尼黑）公司 |
Egfrviii及cd3抗體構築體
|
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究（慕尼黑）公司 |
Ｍｓｌｎ及ｃｄ３抗體構築體
|
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究（慕尼黑）公司 |
Ｃｄ７０及ｃｄ３抗體構築體
|
|
JO3620B1
(ar)
|
2015-08-05 |
2020-08-27 |
Amgen Res Munich Gmbh |
مثبطات نقطة فحص مناعية للاستخدام في علاج سرطانات محمولة عبر الدم
|
|
EP3355908A1
(en)
|
2015-10-01 |
2018-08-08 |
Amgen Inc. |
Treatment of bile acid disorders
|
|
WO2017079215A1
(en)
|
2015-11-03 |
2017-05-11 |
Glycomimetics, Inc. |
Methods and compositions for the production of monoclonal antibodies, hematopoietic stem cells, and methods of using the same
|
|
CA3004680A1
(en)
|
2015-11-13 |
2017-05-18 |
Mavalon Therapeutics Limited |
Substituted tricyclic 1,4-benzodiazepinone derivatives as allosteric modulators of group ii metabotropic glutamate receptors
|
|
US20170157215A1
(en)
|
2015-12-04 |
2017-06-08 |
Jomoco, Corp. |
Compositions and methods to mitigate or prevent an immune response to an immunogenic therapeutic molecule in non-human primates
|
|
EP3386997B1
(en)
|
2015-12-09 |
2021-06-30 |
Medizinische Universität Wien |
Monomaleimide-functionalized platinum compounds for cancer therapy
|
|
EA201891323A1
(ru)
|
2015-12-23 |
2019-02-28 |
Амген Инк. |
Способ лечения или облегчения метаболических нарушений с использованием белков, связывающих рецептор желудочного ингибиторного пептида (gipr), в комбинации с агонистами glp-1
|
|
KR20190031425A
(ko)
|
2016-01-15 |
2019-03-26 |
함부르크대학교 |
O-람노실 잔기를 보유하는 플라보노이드-유형 화합물
|
|
JOP20170017B1
(ar)
|
2016-01-25 |
2021-08-17 |
Amgen Res Munich Gmbh |
تركيب صيدلي يتضمن تركيبات جسم مضاد ثنائي الاختصاص
|
|
EA039859B1
(ru)
|
2016-02-03 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
|
TWI767899B
(zh)
|
2016-02-03 |
2022-06-21 |
德商安美基研究（慕尼黑）公司 |
Psma及cd3雙特異性t細胞嚙合抗體構築體
|
|
ES2905361T3
(es)
|
2016-02-03 |
2022-04-08 |
Amgen Res Munich Gmbh |
Construcciones de anticuerpo de acoplamiento a linfocitos T biespecíficas para BCMA y CD3
|
|
CA3013988A1
(en)
|
2016-02-15 |
2017-08-24 |
Cemm-Forschungszentrum Fur Molekulare Medizin Gmbh |
Taf1 inhibitors for the therapy of cancer
|
|
EP3216458A1
(en)
|
2016-03-07 |
2017-09-13 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Modified vascular endothelial growth factor a (vegf-a) and its medical use
|
|
WO2017176916A1
(en)
|
2016-04-05 |
2017-10-12 |
The Research Foundation For The State University Of New York |
Phosphoserine containing compositions for immune tolerance induction
|
|
GB2555264A
(en)
|
2016-04-15 |
2018-04-25 |
Univ Oxford Innovation Ltd |
Adenosine receptor modulators for the treatment of circadian rhythm disorders
|
|
US10183058B2
(en)
|
2016-06-17 |
2019-01-22 |
Nymox Corporation |
Method of preventing or reducing the progression of prostate cancer
|
|
MA45554A
(fr)
|
2016-07-01 |
2019-05-08 |
Resolve Therapeutics Llc |
Fusions de binucléase optimisées.
|
|
WO2018013924A1
(en)
|
2016-07-15 |
2018-01-18 |
Massachusetts Institute Of Technology |
Synthetic nanoparticles for delivery of immunomodulatory compounds
|
|
EP3269734A1
(en)
|
2016-07-15 |
2018-01-17 |
Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron |
Methods and compositions for the treatment of cancer
|
|
US10172910B2
(en)
|
2016-07-28 |
2019-01-08 |
Nymox Corporation |
Method of preventing or reducing the incidence of acute urinary retention
|
|
US20200030295A1
(en)
|
2016-08-02 |
2020-01-30 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Heterocyclic diamidines
|
|
JP2019527710A
(ja)
|
2016-08-08 |
2019-10-03 |
アムジエン・インコーポレーテツド |
抗スクレロスチン抗体を用いた結合組織付着の改善方法
|
|
US10532081B2
(en)
|
2016-09-07 |
2020-01-14 |
Nymox Corporation |
Method of ameliorating or preventing the worsening or the progression of symptoms of BPH
|
|
KR102613430B1
(ko)
|
2016-10-19 |
2023-12-18 |
더 스크립스 리서치 인스티튜트 |
인간화된 표적화 모이어티 및/또는 최적화된 키메라 항원 수용체-상호작용 도메인을 갖는 키메라 항원 수용체 효과기 세포 스위치 및 이의 용도
|
|
WO2018087401A2
(en)
|
2016-11-14 |
2018-05-17 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Combination of a brd4 inhibitor and an antifolate for the therapy of cancer
|
|
US11091490B2
(en)
|
2016-11-30 |
2021-08-17 |
Medizinische Universität Innsbruck |
3-amino-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-ones as cyclin dependent kinase inhibitors
|
|
WO2018128454A1
(ko)
|
2017-01-06 |
2018-07-12 |
에이비엘바이오 주식회사 |
항 α-SYN 항체 및 그 용도
|
|
JP6908709B2
(ja)
|
2017-01-06 |
2021-07-28 |
エービーエル バイオ インコーポレイテッド |
抗α−ｓｙｎ抗体およびその使用
|
|
JOP20190177A1
(ar)
|
2017-01-17 |
2019-07-16 |
Amgen Inc |
طريقة لعلاج أو تحسين اضطرابات أيضية باستخدام مساعدات مستقبل glp-1 مقترنة بمناهضات لمستقبل ببتيد مثبط معوي (gipr)
|
|
JOP20190189A1
(ar)
|
2017-02-02 |
2019-08-01 |
Amgen Res Munich Gmbh |
تركيبة صيدلانية ذات درجة حموضة منخفضة تتضمن بنيات جسم مضاد يستهدف الخلية t
|
|
SG10201912034UA
(en)
|
2017-02-08 |
2020-02-27 |
Bristol Myers Squibb Co |
Modified relaxin polypeptides comprising a pharmacokinetic enhancer and uses thereof
|
|
US10335453B2
(en)
|
2017-03-01 |
2019-07-02 |
Nymox Corporation |
Compositions and methods for improving sexual function
|
|
WO2018160791A1
(en)
|
2017-03-03 |
2018-09-07 |
Massachusetts Institute Of Technology |
Antimicrobial constructs and uses thereof
|
|
WO2018204907A1
(en)
|
2017-05-05 |
2018-11-08 |
Amgen Inc. |
Pharmaceutical composition comprising bispecific antibody constructs for improved storage and administration
|
|
CA3062749A1
(en)
|
2017-05-12 |
2018-11-15 |
Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. |
Compounds for use in the treatment or prevention of melanoma
|
|
BR112019019740A2
(pt)
|
2017-05-12 |
2020-04-14 |
Mavalon Therapeutics Ltd |
compostos heterocíclicos substituídos como moduladores alostéricos de receptores de glutamato metabotrópicos de grupo ii
|
|
JOP20190259A1
(ar)
|
2017-05-31 |
2019-10-31 |
Amgen Inc |
بروتينات ربط مولد ضد مضادة لـ jagged1
|
|
WO2018236904A1
(en)
|
2017-06-19 |
2018-12-27 |
Surface Oncology, Inc. |
COMBINATION OF ANTI-CD47 ANTIBODIES AND CELL DEATH INDUCING AGENTS, AND USES THEREOF
|
|
WO2018237097A1
(en)
|
2017-06-20 |
2018-12-27 |
Amgen Inc. |
METHOD OF TREATING OR REDUCING METABOLIC DISORDERS USING GASTRIC INHIBITING PEPTIDE RECEPTOR BINDING PROTEINS (GIPR) IN ASSOCIATION WITH GLP-1 AGONISTS
|
|
WO2019014328A2
(en)
|
2017-07-11 |
2019-01-17 |
Compass Therapeutics Llc |
AGONISTIC ANTIBODIES THAT BIND HUMAN CD137 AND USES THEREOF
|
|
CA3070089A1
(en)
|
2017-07-19 |
2019-01-24 |
Auckland Uniservices Limited |
Cytokine modulation
|
|
EP3665202A1
(en)
|
2017-08-09 |
2020-06-17 |
Massachusetts Institute Of Technology |
Albumin binding peptide conjugates and methods thereof
|
|
EP3684811A2
(en)
|
2017-08-17 |
2020-07-29 |
Massachusetts Institute of Technology |
Multiple specificity binders of cxc chemokines and uses thereof
|
|
US10947295B2
(en)
|
2017-08-22 |
2021-03-16 |
Sanabio, Llc |
Heterodimers of soluble interferon receptors and uses thereof
|
|
CA3076337A1
(en)
|
2017-09-19 |
2019-03-28 |
Massachusetts Institute Of Technology |
Compositions for chimeric antigen receptor t cell therapy and uses thereof
|
|
KR20200059281A
(ko)
|
2017-10-04 |
2020-05-28 |
암젠 인크 |
트랜스타이레틴 면역글로불린 융합
|
|
MA50536A
(fr)
|
2017-10-30 |
2020-09-09 |
Enterin Inc |
Nouvelles formes solides de squalamine et procédés pour les produire
|
|
US11718679B2
(en)
|
2017-10-31 |
2023-08-08 |
Compass Therapeutics Llc |
CD137 antibodies and PD-1 antagonists and uses thereof
|
|
WO2019100052A2
(en)
|
2017-11-20 |
2019-05-23 |
Compass Therapeutics Llc |
Cd137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
|
US20210179591A1
(en)
|
2017-12-05 |
2021-06-17 |
Eth Zurich |
New compounds for use as a therapeutically active substance and in particular for use in the treatment of tumors
|
|
MX2020006007A
(es)
|
2017-12-11 |
2020-08-17 |
Amgen Inc |
Procedimiento de fabricacion continuo para productos de anticuerpos biespecificos.
|
|
EP3725806A4
(en)
|
2017-12-14 |
2022-03-30 |
ABL Bio Inc. |
BISPECIFIC ANTIBODIES AGAINST A-SYN/IGF1R AND ASSOCIATED USE
|
|
EP3727447A1
(en)
|
2017-12-19 |
2020-10-28 |
Massachusetts Institute of Technology |
Antigen-adjuvant coupling reagents and methods of use
|
|
TW201940518A
(zh)
|
2017-12-29 |
2019-10-16 |
美商安進公司 |
針對ｍｕｃ１７和ｃｄ３之雙特異性抗體構建體
|
|
KR102411489B1
(ko)
|
2018-03-14 |
2022-06-23 |
서피스 온콜로지, 인크. |
Cd39에 결합하는 항체 및 이의 용도
|
|
AU2019239324A1
(en)
|
2018-03-22 |
2020-10-01 |
Adimab Llc |
Anti-IL-27 antibodies and uses thereof
|
|
CN112166120B
(zh)
|
2018-03-30 |
2024-09-10 |
安姆根有限公司 |
C末端抗体变体
|
|
WO2019193161A1
(en)
|
2018-04-06 |
2019-10-10 |
Universität Wien |
Bumetanide derivatives for the therapy of stroke and other neurological diseases/disorders involving nkccs
|
|
AU2019247641A1
(en)
|
2018-04-06 |
2020-11-12 |
Zilentin AG |
Bumetanide derivatives for the therapy of hyperhidrosis
|
|
AU2019253462A1
(en)
|
2018-04-09 |
2020-11-26 |
Amgen Inc. |
Growth differentiation factor 15 fusion proteins
|
|
WO2019200357A1
(en)
|
2018-04-12 |
2019-10-17 |
Surface Oncology, Inc. |
Biomarker for cd47 targeting therapeutics and uses therefor
|
|
WO2019204743A1
(en)
|
2018-04-19 |
2019-10-24 |
Checkmate Pharmaceuticals, Inc. |
Synthetic rig-i-like receptor agonists
|
|
WO2019207051A1
(en)
|
2018-04-25 |
2019-10-31 |
Università Degli Studi Di Torino |
Medical use of combinations of non-natural semaphorins 3 and antimetabolites
|
|
JP2021525243A
(ja)
|
2018-05-21 |
2021-09-24 |
コンパス セラピューティクス リミテッド ライアビリティ カンパニー |
Ｎｋ細胞による標的細胞の殺傷を増進するための組成物および方法
|
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
|
WO2019225777A1
(ko)
|
2018-05-23 |
2019-11-28 |
에이비엘바이오 주식회사 |
항-ror1 항체 및 그 용도
|
|
WO2019225787A1
(ko)
|
2018-05-24 |
2019-11-28 |
에이비엘바이오 주식회사 |
항-b7-h3 항체 및 그 용도
|
|
US20220275043A1
(en)
|
2018-07-17 |
2022-09-01 |
Massachusetts Institute Of Technology |
Soluble multimeric immunoglobulin-scaffold based fusion proteins and uses thereof
|
|
EP3833442A2
(en)
|
2018-08-09 |
2021-06-16 |
Compass Therapeutics LLC |
Antibodies that bind cd277 and uses thereof
|
|
WO2020033925A2
(en)
|
2018-08-09 |
2020-02-13 |
Compass Therapeutics Llc |
Antibodies that bind cd277 and uses thereof
|
|
US20210388089A1
(en)
|
2018-08-09 |
2021-12-16 |
Compass Therapeutics Llc |
Antigen binding agents that bind cd277 and uses thereof
|
|
US20210317213A1
(en)
|
2018-08-28 |
2021-10-14 |
Ambrx, Inc. |
Anti-CD3 Antibody Folate Bioconjugates and Their Uses
|
|
ES2972137T3
(es)
|
2018-09-11 |
2024-06-11 |
Ambrx Inc |
Conjugados de polipéptidos de interleucina-2 y sus usos
|
|
WO2020053808A1
(en)
|
2018-09-12 |
2020-03-19 |
Georg Dewald |
Method of diagnosing vasoregulatory disorders
|
|
EP3856763A1
(en)
|
2018-09-28 |
2021-08-04 |
Massachusetts Institute of Technology |
Collagen-localized immunomodulatory molecules and methods thereof
|
|
MX2021003976A
(es)
|
2018-10-11 |
2021-05-27 |
Amgen Inc |
Procesamiento posterior de constructos de anticuerpos biespecificos.
|
|
CN113366015A
(zh)
|
2018-10-19 |
2021-09-07 |
Ambrx公司 |
白细胞介素-10多肽缀合物、其二聚体及其用途
|
|
EP3880716A4
(en)
|
2018-11-13 |
2022-08-03 |
Compass Therapeutics LLC |
MULTISPECIFIC BINDING CONSTRUCTS DIRECTED AGAINST CHECKPOINT MOLECULES AND ASSOCIATED USES
|
|
WO2020127200A1
(en)
|
2018-12-17 |
2020-06-25 |
Tolremo Therapeutics Ag |
Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment, amelioration or prevention of cancer
|
|
AU2020204992A1
(en)
|
2019-01-04 |
2021-07-15 |
Resolve Therapeutics, Llc |
Treatment of sjogren's disease with nuclease fusion proteins
|
|
US11235032B2
(en)
|
2019-01-23 |
2022-02-01 |
Massachusetts Institute Of Technology |
Combination immunotherapy dosing regimen for immune checkpoint blockade
|
|
GB201901305D0
(en)
|
2019-01-30 |
2019-03-20 |
Immunocore Ltd |
Specific binding molecules
|
|
BR112021015832A2
(pt)
|
2019-02-12 |
2022-01-18 |
Ambrx Inc |
Composições que contêm conjugados de anticorpo-agonista de tlr, métodos e usos dos mesmos
|
|
KR20220012839A
(ko)
|
2019-03-19 |
2022-02-04 |
펀다시오 프리바다 인스티튜트 드인베스티가시오 온콜로지카 데 발 헤브론 |
Omomyc와 pd-1 또는 ctla-4에 결합하는 항체를 이용한 암 치료용 조합 요법
|
|
WO2020191305A2
(en)
|
2019-03-20 |
2020-09-24 |
Massachusetts Institute Of Technology |
Uses of amphiphiles in immune cell therapy and compositions therefor
|
|
JP2022537650A
(ja)
|
2019-06-13 |
2022-08-29 |
アムジエン・インコーポレーテツド |
生物製剤の製造における自動化された生物量に基づく灌流制御
|
|
JP2022538974A
(ja)
|
2019-06-26 |
2022-09-07 |
マサチューセッツ インスチテュート オブ テクノロジー |
免疫調節融合タンパク質－金属水酸化物錯体およびその方法
|
|
EP3997112A1
(en)
|
2019-07-08 |
2022-05-18 |
Amgen, Inc |
Multispecific transthyretin immunoglobulin fusions
|
|
JP2022542890A
(ja)
|
2019-07-26 |
2022-10-07 |
アムジエン・インコーポレーテツド |
抗ｉｌ１３抗原結合タンパク質
|
|
GB201910899D0
(en)
|
2019-07-31 |
2019-09-11 |
Scancell Ltd |
Binding members
|
|
GB201910900D0
(en)
|
2019-07-31 |
2019-09-11 |
Scancell Ltd |
Modified fc-regions to enhance functional affinity of antibodies and antigen binding fragments thereof
|
|
EP4013788A1
(en)
|
2019-08-12 |
2022-06-22 |
Purinomia Biotech, Inc. |
Methods and compositions for promoting and potentiating t-cell mediated immune responses through adcc targeting of cd39 expressing cells
|
|
JOP20220036A1
(ar)
|
2019-08-13 |
2023-01-30 |
Amgen Inc |
ميوتينات إنترلوكين-2 لتمديد الخلايا التائية التنظيمية
|
|
GB201912657D0
(en)
|
2019-09-03 |
2019-10-16 |
Scancell Ltd |
Binding members
|
|
GB201912882D0
(en)
|
2019-09-06 |
2019-10-23 |
Scancell Ltd |
Ssea-4 binding members
|
|
EP4031178A1
(en)
|
2019-09-16 |
2022-07-27 |
Surface Oncology, Inc. |
Anti-cd39 antibody compositions and methods
|
|
MX2022003719A
(es)
|
2019-09-25 |
2022-04-26 |
Surface Oncology Inc |
Anticuerpos anti-il-27 y sus usos.
|
|
BR112022006394A2
(pt)
|
2019-10-02 |
2022-07-26 |
Tolremo Therapeutics Ag |
Derivados heterocíclicos, composições farmacêuticas e seu uso no tratamento ou melhora do câncer
|
|
WO2021064141A1
(en)
|
2019-10-02 |
2021-04-08 |
Tolremo Therapeutics Ag |
Inhibitors of dual specificity tyrosine phosphorylation regulated kinase 1b
|
|
US20230124700A1
(en)
|
2019-10-16 |
2023-04-20 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Oxazole and thioazole-type cullin ring ubiquitin ligase compounds and uses thereof
|
|
WO2021074418A1
(en)
|
2019-10-16 |
2021-04-22 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Carbazole-type cullin ring ubiquitin ligase compounds and uses thereof
|
|
CN115279905A
(zh)
|
2019-10-23 |
2022-11-01 |
里珍纳龙药品有限公司 |
合成rig-i样受体激动剂
|
|
WO2021080682A1
(en)
|
2019-10-24 |
2021-04-29 |
Massachusetts Institute Of Technology |
Monoclonal antibodies that bind human cd161 and uses thereof
|
|
JP2022554187A
(ja)
|
2019-10-24 |
2022-12-28 |
ミノトール セラピューティクス インコーポレイテッド |
キメラサイトカイン改変抗体およびその使用方法
|
|
US20220396599A1
(en)
|
2019-11-13 |
2022-12-15 |
Amgen Inc. |
Method for Reduced Aggregate Formation in Downstream Processing of Bispecific Antigen-Binding Molecules
|
|
MX2022005914A
(es)
|
2019-11-19 |
2022-08-04 |
Modag Gmbh |
Compuestos novedosos para el diagnostico, tratamiento y prevencion de enfermedades asociadas con la agregacion de alfa-sinucleina.
|
|
KR20220114595A
(ko)
|
2019-12-17 |
2022-08-17 |
암젠 인크 |
치료에서의 사용을 위한 이중 인터류킨-2/tnf 수용체 효현제
|
|
KR20220122628A
(ko)
|
2020-01-06 |
2022-09-02 |
백시넥스 인코포레이티드 |
항-ccr8 항체 및 이의 용도
|
|
WO2021173889A1
(en)
|
2020-02-26 |
2021-09-02 |
Ambrx, Inc. |
Uses of anti-cd3 antibody folate bioconjugates
|
|
EP4117732A1
(en)
|
2020-03-11 |
2023-01-18 |
Ambrx, Inc. |
Interleukin-2 polypeptide conjugates and methods of use thereof
|
|
US20230129844A1
(en)
|
2020-03-19 |
2023-04-27 |
Amgen Inc. |
Diagnostic antibodies against mucin 17 and uses thereof
|
|
WO2021221783A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
|
US20210338833A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Chimeric antigen receptor-targeting ligands and uses thereof
|
|
GB202101299D0
(en)
|
2020-06-09 |
2021-03-17 |
Avacta Life Sciences Ltd |
Diagnostic polypetides and methods
|
|
CA3184062A1
(en)
|
2020-06-25 |
2021-12-30 |
Stefanie Fluckiger-Mangual |
Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment, amelioration or prevention of fibrotic disease
|
|
EP4171614A1
(en)
|
2020-06-29 |
2023-05-03 |
Resolve Therapeutics, LLC |
Treatment of sjogren's syndrome with nuclease fusion proteins
|
|
EP3939578A1
(en)
|
2020-07-13 |
2022-01-19 |
Novaremed Ltd. |
Compounds for treatment or prevention of an infection resulting from a coronavirus and/or a coronavirus-induced disease
|
|
WO2022023292A2
(en)
|
2020-07-31 |
2022-02-03 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Corona virus spike protein-targeting antibodies and use thereof
|
|
CA3190606A1
(en)
|
2020-08-20 |
2022-02-24 |
Ambrx, Inc. |
Antibody-tlr agonist conjugates, methods and uses thereof
|
|
WO2022043400A1
(en)
|
2020-08-26 |
2022-03-03 |
Scancell Limited |
Nucleic acids encoding a polypeptide comprising a modified fc region of a human igg1 and at least one heterologous antigen
|
|
EP3964497A1
(en)
|
2020-09-04 |
2022-03-09 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Substituted vicinal diamine compounds and their use in the treatment, amelioration or prevention of pain
|
|
WO2022081436A1
(en)
|
2020-10-15 |
2022-04-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibody specific for sars-cov-2 receptor binding domain and therapeutic methods
|
|
CA3194868A1
(en)
|
2020-10-16 |
2022-04-21 |
Georg Winter |
Heterocyclic cullin ring ubiquitin ligase compounds and uses thereof
|
|
WO2022087274A1
(en)
|
2020-10-21 |
2022-04-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibodies that neutralize type-i interferon (ifn) activity
|
|
WO2022096716A2
(en)
|
2020-11-06 |
2022-05-12 |
Amgen Inc. |
Multitargeting bispecific antigen-binding molecules of increased selectivity
|
|
AU2022224636A1
(en)
|
2021-02-19 |
2023-09-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Single domain antibodies that neutralize sars-cov-2
|
|
WO2022212899A1
(en)
|
2021-04-03 |
2022-10-06 |
Ambrx, Inc. |
Anti-her2 antibody-drug conjugates and uses thereof
|
|
IL307402A
(en)
|
2021-04-07 |
2023-12-01 |
Tolremo Therapeutics Ag |
The tercyclic derivatives, pharmaceutical compounds and their use in the treatment or amelioration of cancer
|
|
CA3217865A1
(en)
|
2021-04-28 |
2022-11-03 |
Minotaur Therapeutics, Inc. |
Humanized chimeric bovine antibodies and methods of use
|
|
CN117279947A
(zh)
|
2021-05-06 |
2023-12-22 |
安进研发（慕尼黑）股份有限公司 |
用于在增殖性疾病中使用的靶向cd20和cd22的抗原结合分子
|
|
KR20240005809A
(ko)
|
2021-05-07 |
2024-01-12 |
서피스 온콜로지, 엘엘씨 |
항-il-27 항체 및 이의 용도
|
|
KR20240035394A
(ko)
|
2021-05-14 |
2024-03-15 |
클라리스 바이오쎄라퓨틱스, 인코포레이티드 |
안질환 치료를 위한 성장 인자 조성물
|
|
AR126971A1
(es)
|
2021-09-03 |
2023-12-06 |
Univ Of Bern |
Composiciones y métodos para tratar el síndrome de qt largo
|
|
CA3237018A1
(en)
|
2021-11-03 |
2023-05-11 |
Joachim Koch |
Bispecific cd16a binders
|
|
IL312060A
(en)
|
2021-11-03 |
2024-06-01 |
Affimed Gmbh |
Bispecific CD16A binders
|
|
US20230364031A1
(en)
|
2022-04-19 |
2023-11-16 |
Garth Cooper |
Treatment of brain copper disorders
|
|
WO2023203172A1
(en)
|
2022-04-20 |
2023-10-26 |
Proxygen Gmbh |
Heterocyclic cullin ring ubiquitin ligase compounds and uses thereof
|
|
TW202346368A
(zh)
|
2022-05-12 |
2023-12-01 |
德商安美基研究（慕尼黑）公司 |
具有增加的選擇性的多鏈多靶向性雙特異性抗原結合分子
|
|
US20240026001A1
(en)
|
2022-05-25 |
2024-01-25 |
Surface Oncology, Inc. |
Use of anti-il-27 antibodies
|
|
US20240025987A1
(en)
|
2022-05-25 |
2024-01-25 |
Surface Oncology, Inc. |
Use of anti-il-27 antibodies
|
|
WO2024050526A1
(en)
|
2022-09-02 |
2024-03-07 |
Biomarin Pharmaceutical Inc. |
Compositions and methods for treating long qt syndrome
|
|
TW202421650A
(zh)
|
2022-09-14 |
2024-06-01 |
美商安進公司 |
雙特異性分子穩定組成物
|
|
WO2024076995A1
(en)
|
2022-10-03 |
2024-04-11 |
Insigna Inc. |
Compositions for non-surgical prevention of boar taint and aggressive behavior
|
|
WO2024089013A1
(en)
|
2022-10-25 |
2024-05-02 |
Peptomyc, S.L. |
Combination therapy for the treatment of cancer
|
|
WO2024121796A1
(en)
|
2022-12-07 |
2024-06-13 |
Fondazione Matilde Tettamanti E Menotti De Marchi Onlus |
Methods for generating genetically modified cytokine induced killer (cik) cells
|