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DK43279A - Fremgangsmaade til fremstilling af 2-penem-3-carboxylsyreforbindelser - Google Patents

Fremgangsmaade til fremstilling af 2-penem-3-carboxylsyreforbindelser

Info

Publication number
DK43279A
DK43279A DK43279A DK43279A DK43279A DK 43279 A DK43279 A DK 43279A DK 43279 A DK43279 A DK 43279A DK 43279 A DK43279 A DK 43279A DK 43279 A DK43279 A DK 43279A
Authority
DK
Denmark
Prior art keywords
penem
preparing
procedure
carboxylic acid
acid compounds
Prior art date
Application number
DK43279A
Other languages
English (en)
Other versions
DK160099B (da
DK160099C (da
Inventor
J Gosteli
I Ernest
M Lang
R B Woodward
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of DK43279A publication Critical patent/DK43279A/da
Publication of DK160099B publication Critical patent/DK160099B/da
Application granted granted Critical
Publication of DK160099C publication Critical patent/DK160099C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK043279A 1978-02-02 1979-02-01 Analogifremgangsmaade til fremstilling af optisk aktive eller racemiske 6-substituerede 2-penem-3-carboxylsyreforbindelser eller farmaceutisk anvendelige salte deraf DK160099C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH114078 1978-02-02
CH114078 1978-02-02

Publications (3)

Publication Number Publication Date
DK43279A true DK43279A (da) 1979-08-03
DK160099B DK160099B (da) 1991-01-28
DK160099C DK160099C (da) 1991-06-24

Family

ID=4203421

Family Applications (1)

Application Number Title Priority Date Filing Date
DK043279A DK160099C (da) 1978-02-02 1979-02-01 Analogifremgangsmaade til fremstilling af optisk aktive eller racemiske 6-substituerede 2-penem-3-carboxylsyreforbindelser eller farmaceutisk anvendelige salte deraf

Country Status (23)

Country Link
US (2) US4692442A (da)
EP (2) EP0003960B1 (da)
JP (3) JPS54119486A (da)
AR (1) AR228236A1 (da)
AT (1) AT362876B (da)
AU (1) AU519317B2 (da)
CA (1) CA1340273C (da)
CS (1) CS222279B2 (da)
DD (1) DD142342A5 (da)
DK (1) DK160099C (da)
ES (1) ES477336A1 (da)
FI (1) FI73219C (da)
GB (1) GB2013674A (da)
GR (1) GR72911B (da)
HU (1) HU182017B (da)
IE (1) IE48776B1 (da)
IL (1) IL56557A (da)
NO (1) NO158679C (da)
NZ (1) NZ189530A (da)
PL (1) PL122371B1 (da)
PT (1) PT69166A (da)
SU (1) SU925252A3 (da)
ZA (1) ZA79433B (da)

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US4282150A (en) 1978-12-18 1981-08-04 Bristol-Myers Company 2,6-Disubstituted penem compounds
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FI75163C (fi) * 1979-02-24 1988-05-09 Erba Farmitalia Foerfarande foer framstaellning av nya penemkarboxylsyror eller -estrar.
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US4374065A (en) 1979-09-21 1983-02-15 Bristol-Myers Company Antibacterial agents of the β-lactam type
US4378314A (en) 1979-09-21 1983-03-29 Bristol Myers Company Antibacterial agents and metal containing azetidinone intermediates therefore
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FR2483924A1 (fr) * 1980-06-06 1981-12-11 Sankyo Co Derives d'acide peneme-3-carboxylique, leurs procedes de preparation et leur application en therapeutique
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CA1190236A (en) * 1981-10-23 1985-07-09 Edward J.J. Grabowski Antibiotic synthesis
US4411906A (en) * 1981-11-25 1983-10-25 Schering Corporation (5R,6S,8R)-6-(1-Hydroxyethyl)-2-(2-fluoroethylthio)-penem-3-carboxylates
AT379399B (de) * 1981-12-11 1985-12-27 Erba Farmitalia Verfahren zur herstellung von optisch aktiven penemen
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JPS591464A (ja) * 1982-06-26 1984-01-06 Sankyo Co Ltd β−ラクタム化合物及びその製法
KR900007181B1 (ko) * 1982-07-08 1990-09-29 훽스트 유케이 리미티드 펜엠 유도체의 제조방법
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EP0125207A1 (de) * 1983-05-06 1984-11-14 Ciba-Geigy Ag 2-Tetrazolylpropyl-2-penem-Verbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
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US5104862A (en) * 1991-03-20 1992-04-14 Merck & Co., Inc. Bethalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone
US5100880A (en) * 1991-03-20 1992-03-31 Merck & Co., Inc. Novel betalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone
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US5348953A (en) * 1991-06-25 1994-09-20 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
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Also Published As

Publication number Publication date
JPH01110668A (ja) 1989-04-27
CS222279B2 (en) 1983-06-24
US4692442A (en) 1987-09-08
PL122371B1 (en) 1982-07-31
HU182017B (en) 1983-12-28
FI73219C (fi) 1987-09-10
AU4384379A (en) 1979-08-09
CA1340273C (en) 1998-12-15
SU925252A3 (ru) 1982-04-30
JPS62129264A (ja) 1987-06-11
DK160099B (da) 1991-01-28
IL56557A (en) 1982-01-31
PT69166A (de) 1979-03-01
IL56557A0 (en) 1979-03-12
NO158679B (no) 1988-07-11
IE48776B1 (en) 1985-05-15
JPS54119486A (en) 1979-09-17
GB2013674A (en) 1979-08-15
EP0003960A1 (de) 1979-09-19
DD142342A5 (de) 1980-06-18
ATA74579A (de) 1980-11-15
FI73219B (fi) 1987-05-29
JPH0329789B2 (da) 1991-04-25
JPH0314037B2 (da) 1991-02-25
JPH045677B2 (da) 1992-02-03
IE790191L (en) 1979-08-02
EP0003960B1 (de) 1983-06-29
AU519317B2 (en) 1981-11-26
DK160099C (da) 1991-06-24
AR228236A1 (es) 1983-02-15
EP0042026A1 (de) 1981-12-23
EP0042026B1 (de) 1986-01-08
NZ189530A (en) 1982-02-23
FI790321A (fi) 1979-08-03
AT362876B (de) 1981-06-25
ZA79433B (en) 1980-02-27
US4952690A (en) 1990-08-28
GR72911B (da) 1984-01-05
NO158679C (no) 1988-10-19
PL213133A1 (da) 1980-03-10
NO790332L (no) 1979-08-03
ES477336A1 (es) 1979-07-01

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