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DK3737403T3 - Modificerede adenovira - Google Patents

Modificerede adenovira Download PDF

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Publication number
DK3737403T3
DK3737403T3 DK19711157.8T DK19711157T DK3737403T3 DK 3737403 T3 DK3737403 T3 DK 3737403T3 DK 19711157 T DK19711157 T DK 19711157T DK 3737403 T3 DK3737403 T3 DK 3737403T3
Authority
DK
Denmark
Prior art keywords
adenovira
modified
modified adenovira
Prior art date
Application number
DK19711157.8T
Other languages
English (en)
Other versions
DK3737403T5 (da
Inventor
Alan Parker
Hanni Uusi-Kerttula
Original Assignee
Univ College Cardiff Consultants Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ College Cardiff Consultants Ltd filed Critical Univ College Cardiff Consultants Ltd
Publication of DK3737403T3 publication Critical patent/DK3737403T3/da
Application granted granted Critical
Publication of DK3737403T5 publication Critical patent/DK3737403T5/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • A61K35/761Adenovirus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10321Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10332Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10345Special targeting system for viral vectors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK19711157.8T 2018-02-16 2019-02-13 Modificerede adenovira DK3737403T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1802539.5A GB201802539D0 (en) 2018-02-16 2018-02-16 Modified adenoviruses
PCT/GB2019/050380 WO2019158914A1 (en) 2018-02-16 2019-02-13 Modified adenoviruses

Publications (2)

Publication Number Publication Date
DK3737403T3 true DK3737403T3 (da) 2024-01-22
DK3737403T5 DK3737403T5 (da) 2024-08-26

Family

ID=61783770

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19711157.8T DK3737403T5 (da) 2018-02-16 2019-02-13 Modificerede adenovira

Country Status (16)

Country Link
US (1) US20210100855A1 (da)
EP (1) EP3737403B1 (da)
JP (2) JP2021513843A (da)
KR (1) KR102687425B1 (da)
CN (2) CN118834841A (da)
AU (1) AU2019220607B2 (da)
CA (1) CA3090859A1 (da)
DK (1) DK3737403T5 (da)
ES (1) ES2968387T3 (da)
FI (1) FI3737403T3 (da)
GB (1) GB201802539D0 (da)
IL (1) IL276535A (da)
PL (1) PL3737403T3 (da)
PT (1) PT3737403T (da)
SG (1) SG11202007470QA (da)
WO (1) WO2019158914A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2903582C (en) 2013-03-14 2021-06-08 Salk Institute For Biological Studies Oncolytic adenovirus compositions
AU2017222568B2 (en) 2016-02-23 2020-09-10 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
EP4155411A1 (en) 2016-02-23 2023-03-29 Salk Institute for Biological Studies Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
AU2017375633C1 (en) 2016-12-12 2023-04-27 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
JP2024512985A (ja) * 2021-03-29 2024-03-21 ユニバーシティ カレッジ カーディフ コンサルタンツ リミテッド 改変アデノウイルス
GB202214580D0 (en) 2022-10-04 2022-11-16 Univ College Cardiff Consultants Ltd Adenoviral vector therapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007525166A (ja) * 2003-03-28 2007-09-06 ザ・スクリップス・リサーチ・インスティテュート 樹状細胞に対する感染性が増大したアデノウイルス粒子と、肝細胞に対する感染性が低下した粒子
GB0520068D0 (en) * 2005-10-03 2005-11-09 Cancer Res Technology av peptide ligand
WO2008110579A2 (en) * 2007-03-14 2008-09-18 Institut Català D'oncologia Adenovirus with mutations in the endoplasmic reticulum retention domain of the e3-19k protein and their use in cancer treatment.
CN102014948A (zh) * 2008-02-07 2011-04-13 安德鲁·贝克 腺病毒向性的调节
SG188550A1 (en) * 2010-09-24 2013-04-30 Oncos Therapeutics Oy Oncolytic adenoviral vectors and methods and uses related thereto
JP2018504141A (ja) * 2015-01-20 2018-02-15 アドキュア バイオテクノロジーズ、 エルエルシー 非標的化アデノウイルス変異体および関連する方法

Also Published As

Publication number Publication date
US20210100855A1 (en) 2021-04-08
EP3737403B1 (en) 2024-01-03
CN112020368B (zh) 2024-07-12
CA3090859A1 (en) 2019-08-22
AU2019220607B2 (en) 2024-02-15
KR20200122346A (ko) 2020-10-27
SG11202007470QA (en) 2020-09-29
FI3737403T3 (fi) 2024-01-17
WO2019158914A1 (en) 2019-08-22
CN118834841A (zh) 2024-10-25
PT3737403T (pt) 2024-01-24
JP2021513843A (ja) 2021-06-03
JP2024020345A (ja) 2024-02-14
IL276535A (en) 2020-09-30
PL3737403T3 (pl) 2024-03-18
KR102687425B1 (ko) 2024-07-22
AU2019220607A1 (en) 2020-09-17
EP3737403A1 (en) 2020-11-18
GB201802539D0 (en) 2018-04-04
DK3737403T5 (da) 2024-08-26
ES2968387T3 (es) 2024-05-09
CN112020368A (zh) 2020-12-01

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