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DK3564230T3 - Substituerede guanidinforbindelser - Google Patents

Substituerede guanidinforbindelser Download PDF

Info

Publication number
DK3564230T3
DK3564230T3 DK17886109.2T DK17886109T DK3564230T3 DK 3564230 T3 DK3564230 T3 DK 3564230T3 DK 17886109 T DK17886109 T DK 17886109T DK 3564230 T3 DK3564230 T3 DK 3564230T3
Authority
DK
Denmark
Prior art keywords
substituted
guanide
compounds
guanide compounds
substituted guanide
Prior art date
Application number
DK17886109.2T
Other languages
English (en)
Inventor
Ken-Ichi Komori
Akishi Ninomiya
Shigeru Ushiyama
Masaru Shinohara
Koji Ito
Tetsuo Kawaguchi
Yasunori Tokunaga
Hiroyoshi Kawada
Haruka Yamada
Yusuke Shiraishi
Masahiro Kojima
Masaaki Ito
Tomio Kimura
Original Assignee
Ube Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ube Industries filed Critical Ube Industries
Application granted granted Critical
Publication of DK3564230T3 publication Critical patent/DK3564230T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • C07D491/107Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK17886109.2T 2016-12-28 2017-12-27 Substituerede guanidinforbindelser DK3564230T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016255567 2016-12-28
PCT/JP2017/046898 WO2018124179A1 (ja) 2016-12-28 2017-12-27 置換グアニジン化合物

Publications (1)

Publication Number Publication Date
DK3564230T3 true DK3564230T3 (da) 2022-03-28

Family

ID=62709416

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17886109.2T DK3564230T3 (da) 2016-12-28 2017-12-27 Substituerede guanidinforbindelser

Country Status (21)

Country Link
US (2) US11396514B2 (da)
EP (1) EP3564230B1 (da)
JP (1) JP7103228B2 (da)
KR (1) KR102607007B1 (da)
CN (1) CN110114350B (da)
AU (1) AU2017385291B2 (da)
BR (1) BR112019012020A8 (da)
CA (1) CA3048854A1 (da)
CY (1) CY1125090T1 (da)
DK (1) DK3564230T3 (da)
ES (1) ES2909133T3 (da)
HR (1) HRP20220383T1 (da)
HU (1) HUE058181T2 (da)
LT (1) LT3564230T (da)
MX (1) MX2019007786A (da)
PL (1) PL3564230T3 (da)
PT (1) PT3564230T (da)
RS (1) RS63103B1 (da)
RU (1) RU2757279C2 (da)
SI (1) SI3564230T1 (da)
WO (1) WO2018124179A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020083264A1 (zh) * 2018-10-22 2020-04-30 广东东阳光药业有限公司 胍类衍生物及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070254931A1 (en) * 2004-07-27 2007-11-01 Astellas Pharma Inc. Thiazole Derivatives Having Vap-1 Inhibitory Activity
TWI490214B (zh) * 2008-05-30 2015-07-01 艾德克 上野股份有限公司 苯或噻吩衍生物及該等作為vap-1抑制劑之用途
EA201200046A1 (ru) 2009-06-24 2012-08-30 Бёрингер Ингельхайм Интернациональ Гмбх Новые соединения, фармацевтическая композиция и связанные с ними способы
AU2010296420A1 (en) 2009-09-16 2012-03-22 Astellas Pharma Inc. Glycine compound
DK3002278T3 (da) * 2011-03-15 2017-07-24 Astellas Pharma Inc Guanidinforbindelse
WO2017022861A1 (ja) * 2015-08-06 2017-02-09 宇部興産株式会社 置換グアニジン誘導体

Also Published As

Publication number Publication date
US20220315599A1 (en) 2022-10-06
ES2909133T3 (es) 2022-05-05
PL3564230T3 (pl) 2022-05-09
PT3564230T (pt) 2022-05-19
RU2757279C2 (ru) 2021-10-12
HUE058181T2 (hu) 2022-07-28
EP3564230A1 (en) 2019-11-06
MX2019007786A (es) 2019-08-16
KR20190097251A (ko) 2019-08-20
AU2017385291B2 (en) 2021-02-11
BR112019012020A8 (pt) 2023-01-17
RS63103B1 (sr) 2022-04-29
KR102607007B1 (ko) 2023-11-29
EP3564230B1 (en) 2022-02-09
AU2017385291A1 (en) 2019-07-18
US11814393B2 (en) 2023-11-14
JP7103228B2 (ja) 2022-07-20
RU2019123574A3 (da) 2021-03-25
US20190337962A1 (en) 2019-11-07
CY1125090T1 (el) 2024-02-16
JPWO2018124179A1 (ja) 2019-10-31
CN110114350A (zh) 2019-08-09
WO2018124179A1 (ja) 2018-07-05
HRP20220383T1 (hr) 2022-05-13
LT3564230T (lt) 2022-04-11
CN110114350B (zh) 2022-03-04
RU2019123574A (ru) 2021-01-29
US11396514B2 (en) 2022-07-26
CA3048854A1 (en) 2018-07-05
BR112019012020A2 (pt) 2019-10-29
EP3564230A4 (en) 2020-06-03
SI3564230T1 (sl) 2022-05-31

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