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DK3597189T3 - Krystallinske forbindelser - Google Patents

Krystallinske forbindelser Download PDF

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Publication number
DK3597189T3
DK3597189T3 DK19196556.5T DK19196556T DK3597189T3 DK 3597189 T3 DK3597189 T3 DK 3597189T3 DK 19196556 T DK19196556 T DK 19196556T DK 3597189 T3 DK3597189 T3 DK 3597189T3
Authority
DK
Denmark
Prior art keywords
crystallinic
compounds
crystallinic compounds
Prior art date
Application number
DK19196556.5T
Other languages
English (en)
Inventor
Franklin Bymaster
Walter Piskorski
Fred J Fleitz
Yonglai Yang
David A Engers
Valeriya Smolenskaya
Venkat Kusukuntla
Anthony Alexander Mckinney
Original Assignee
Otsuka America Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka America Pharmaceutical Inc filed Critical Otsuka America Pharmaceutical Inc
Application granted granted Critical
Publication of DK3597189T3 publication Critical patent/DK3597189T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/16Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings
    • C07C211/17Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings containing only non-condensed rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
DK19196556.5T 2015-06-17 2016-06-17 Krystallinske forbindelser DK3597189T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562181174P 2015-06-17 2015-06-17
EP16812592.0A EP3310352A4 (en) 2015-06-17 2016-06-17 CRYSTALLINE COMPOUNDS

Publications (1)

Publication Number Publication Date
DK3597189T3 true DK3597189T3 (da) 2022-06-27

Family

ID=57546597

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19196556.5T DK3597189T3 (da) 2015-06-17 2016-06-17 Krystallinske forbindelser

Country Status (24)

Country Link
US (5) US9708261B2 (da)
EP (3) EP3597189B1 (da)
JP (2) JP6896651B2 (da)
KR (1) KR102593783B1 (da)
CN (3) CN117466800A (da)
AU (2) AU2016279075C1 (da)
CA (2) CA2989431C (da)
DK (1) DK3597189T3 (da)
ES (1) ES2922158T3 (da)
HK (1) HK1247125A1 (da)
HR (1) HRP20220829T1 (da)
HU (1) HUE059348T2 (da)
LT (1) LT3597189T (da)
MX (2) MX2017016430A (da)
MY (1) MY194868A (da)
NZ (2) NZ776973A (da)
PH (1) PH12017502324A1 (da)
PL (1) PL3597189T3 (da)
PT (1) PT3597189T (da)
SA (1) SA517390552B1 (da)
SG (1) SG10201911417PA (da)
SI (1) SI3597189T1 (da)
TW (1) TWI751998B (da)
WO (1) WO2016205762A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070082940A1 (en) 2005-07-27 2007-04-12 Phil Skolnick Novel 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
US20140206740A1 (en) 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters
US9839627B2 (en) 2013-12-09 2017-12-12 Neurovance, Inc. Methods of treating fragile X associated disorders, ADHD, and autism spectrum disorder
WO2016205762A1 (en) 2015-06-17 2016-12-22 Anthony Alexander Mckinney Crystalline compounds
US11149004B2 (en) * 2017-12-11 2021-10-19 Crystal Pharmaceutical (Suzhou) Co., Ltd. Crystalline form of EB-1020, processes for preparation and use thereof
US20240140910A1 (en) 2019-10-16 2024-05-02 Otsuka Pharmaceutical Co., Ltd. Method for producing centanafadine
EP4347564A1 (en) 2021-05-31 2024-04-10 Teva Pharmaceuticals International GmbH Solid state form of centanafadine hcl and process for preparation thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2005117630A (ru) 2002-11-08 2006-01-20 Дов Фармасьютикал, Инк. (Us) Полиморфы гидрохлорида бицифадина
HUE029459T2 (en) 2004-04-19 2017-02-28 Krka Tovarna Zdravil D D Novo Mesto Methods for the Preparation of Polymorph Form I of Clopidogrel Hydrogen Sulphate
US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
NZ589033A (en) 2004-08-18 2012-06-29 Dov Pharmaceutical Inc Novel polymorphs of azabicyclohexane
US20070082939A1 (en) 2005-07-26 2007-04-12 Lippa Arnold S Methods and compositions for the treatment of neuropathies and related disorders
US20070082940A1 (en) 2005-07-27 2007-04-12 Phil Skolnick Novel 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
US7919598B2 (en) 2006-06-28 2011-04-05 Bristol-Myers Squibb Company Crystal structures of SGLT2 inhibitors and processes for preparing same
US20080058535A1 (en) * 2006-07-25 2008-03-06 Zhengming Chen Methods and compositions for production, formulation and use of 1 aryl-3-azabicyclo[3.1.0]hexanes
US8576985B2 (en) 2009-09-01 2013-11-05 Aptuit (West Lafayette) Llc Methods for indexing solid forms of compounds
KR20130105675A (ko) 2010-11-25 2013-09-25 라티오팜 게엠베하 아파티닙의 신규 염 및 다형
US20140206740A1 (en) 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters
HUE048715T2 (hu) * 2011-07-30 2020-09-28 Otsuka America Pharmaceutical Inc (1R,5S)-(+)-l-(naftalen-2-il)-3-azabiciklo[3.1.0]hexán alkalmazása monoamin neurotranszmitterek által befolyásolt állapotok kezelésében
US20140228421A1 (en) 2011-09-07 2014-08-14 Anthony McKinney Methods For Inhibiting Native And Promiscuous Uptake Of Monoamine Neurotransmitters
US9839627B2 (en) 2013-12-09 2017-12-12 Neurovance, Inc. Methods of treating fragile X associated disorders, ADHD, and autism spectrum disorder
WO2016205762A1 (en) 2015-06-17 2016-12-22 Anthony Alexander Mckinney Crystalline compounds

Also Published As

Publication number Publication date
US9856217B2 (en) 2018-01-02
LT3597189T (lt) 2022-07-11
CN117088802A (zh) 2023-11-21
US20180194726A1 (en) 2018-07-12
PL3597189T3 (pl) 2022-07-25
SG10201911417PA (en) 2020-01-30
AU2016279075C1 (en) 2021-04-01
PT3597189T (pt) 2022-07-05
PH12017502324A1 (en) 2018-06-25
MX2017016430A (es) 2018-11-09
KR102593783B1 (ko) 2023-10-25
US20210198198A1 (en) 2021-07-01
HK1247125A1 (zh) 2018-09-21
RU2018101244A (ru) 2019-07-22
JP6896651B2 (ja) 2021-06-30
CN117466800A (zh) 2024-01-30
NZ739044A (en) 2022-08-26
SI3597189T1 (sl) 2022-08-31
RU2018101244A3 (da) 2019-12-23
US20160368871A1 (en) 2016-12-22
KR20180014830A (ko) 2018-02-09
EP3310352A4 (en) 2019-03-13
US9708261B2 (en) 2017-07-18
AU2021200314B2 (en) 2022-08-04
US11299458B2 (en) 2022-04-12
TW201800392A (zh) 2018-01-01
WO2016205762A1 (en) 2016-12-22
MX2020009949A (es) 2020-10-16
EP3597189B1 (en) 2022-06-01
CA2989431A1 (en) 2016-12-22
HRP20220829T1 (hr) 2022-12-23
NZ776973A (en) 2022-11-25
SA517390552B1 (ar) 2022-04-13
HUE059348T2 (hu) 2022-11-28
US10800740B2 (en) 2020-10-13
AU2016279075B2 (en) 2020-10-22
US20170334850A1 (en) 2017-11-23
US10280141B2 (en) 2019-05-07
CA3200692A1 (en) 2016-12-22
CN107921021A (zh) 2018-04-17
EP3310352A1 (en) 2018-04-25
EP4049997A1 (en) 2022-08-31
ES2922158T3 (es) 2022-09-09
AU2016279075A1 (en) 2018-02-01
CA2989431C (en) 2023-08-29
EP3597189A1 (en) 2020-01-22
US20200039934A1 (en) 2020-02-06
TWI751998B (zh) 2022-01-11
AU2021200314A1 (en) 2021-03-18
JP7244575B2 (ja) 2023-03-22
JP2018517742A (ja) 2018-07-05
JP2021138747A (ja) 2021-09-16
JP2023071978A (ja) 2023-05-23
MY194868A (en) 2022-12-21

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