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PT3564230T - Compostos de guanidina substituídos - Google Patents

Compostos de guanidina substituídos

Info

Publication number
PT3564230T
PT3564230T PT178861092T PT17886109T PT3564230T PT 3564230 T PT3564230 T PT 3564230T PT 178861092 T PT178861092 T PT 178861092T PT 17886109 T PT17886109 T PT 17886109T PT 3564230 T PT3564230 T PT 3564230T
Authority
PT
Portugal
Prior art keywords
guanidine compound
substituted guanidine
substituted
compound
guanidine
Prior art date
Application number
PT178861092T
Other languages
English (en)
Original Assignee
Ube Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ube Industries filed Critical Ube Industries
Publication of PT3564230T publication Critical patent/PT3564230T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • C07D491/107Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
PT178861092T 2016-12-28 2017-12-27 Compostos de guanidina substituídos PT3564230T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2016255567 2016-12-28

Publications (1)

Publication Number Publication Date
PT3564230T true PT3564230T (pt) 2022-05-19

Family

ID=62709416

Family Applications (1)

Application Number Title Priority Date Filing Date
PT178861092T PT3564230T (pt) 2016-12-28 2017-12-27 Compostos de guanidina substituídos

Country Status (21)

Country Link
US (2) US11396514B2 (pt)
EP (1) EP3564230B1 (pt)
JP (1) JP7103228B2 (pt)
KR (1) KR102607007B1 (pt)
CN (1) CN110114350B (pt)
AU (1) AU2017385291B2 (pt)
BR (1) BR112019012020A8 (pt)
CA (1) CA3048854A1 (pt)
CY (1) CY1125090T1 (pt)
DK (1) DK3564230T3 (pt)
ES (1) ES2909133T3 (pt)
HR (1) HRP20220383T1 (pt)
HU (1) HUE058181T2 (pt)
LT (1) LT3564230T (pt)
MX (1) MX2019007786A (pt)
PL (1) PL3564230T3 (pt)
PT (1) PT3564230T (pt)
RS (1) RS63103B1 (pt)
RU (1) RU2757279C2 (pt)
SI (1) SI3564230T1 (pt)
WO (1) WO2018124179A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020083264A1 (zh) * 2018-10-22 2020-04-30 广东东阳光药业有限公司 胍类衍生物及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2324922T3 (es) * 2004-07-27 2009-08-19 Astellas Pharma Inc. Derivados de tiazol que tienen actividad inhibidora de vap-1.
TWI490214B (zh) * 2008-05-30 2015-07-01 艾德克 上野股份有限公司 苯或噻吩衍生物及該等作為vap-1抑制劑之用途
WO2010149684A1 (en) 2009-06-24 2010-12-29 Boehringer Ingelheim International Gmbh New compounds, pharmaceutical composition and methods relating thereto
RU2012114846A (ru) 2009-09-16 2013-10-27 Астеллас Фарма Инк. Соединение глицина
HUE034860T2 (en) * 2011-03-15 2018-03-28 Astellas Pharma Inc Guanidine compound
US10759781B2 (en) 2015-08-06 2020-09-01 Ube Industries, Ltd. Substituted guanidine derivatives

Also Published As

Publication number Publication date
HUE058181T2 (hu) 2022-07-28
EP3564230A4 (en) 2020-06-03
CN110114350A (zh) 2019-08-09
KR20190097251A (ko) 2019-08-20
EP3564230A1 (en) 2019-11-06
US11396514B2 (en) 2022-07-26
MX2019007786A (es) 2019-08-16
RU2757279C2 (ru) 2021-10-12
SI3564230T1 (sl) 2022-05-31
BR112019012020A8 (pt) 2023-01-17
RU2019123574A (ru) 2021-01-29
AU2017385291B2 (en) 2021-02-11
LT3564230T (lt) 2022-04-11
US11814393B2 (en) 2023-11-14
PL3564230T3 (pl) 2022-05-09
RS63103B1 (sr) 2022-04-29
US20220315599A1 (en) 2022-10-06
DK3564230T3 (da) 2022-03-28
KR102607007B1 (ko) 2023-11-29
WO2018124179A1 (ja) 2018-07-05
BR112019012020A2 (pt) 2019-10-29
CN110114350B (zh) 2022-03-04
JPWO2018124179A1 (ja) 2019-10-31
CA3048854A1 (en) 2018-07-05
JP7103228B2 (ja) 2022-07-20
RU2019123574A3 (pt) 2021-03-25
AU2017385291A1 (en) 2019-07-18
HRP20220383T1 (hr) 2022-05-13
US20190337962A1 (en) 2019-11-07
ES2909133T3 (es) 2022-05-05
CY1125090T1 (el) 2024-02-16
EP3564230B1 (en) 2022-02-09

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