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DK26093A - Fremgangsmaade til fremstilling af clavulansyresalte - Google Patents

Fremgangsmaade til fremstilling af clavulansyresalte

Info

Publication number
DK26093A
DK26093A DK026093A DK26093A DK26093A DK 26093 A DK26093 A DK 26093A DK 026093 A DK026093 A DK 026093A DK 26093 A DK26093 A DK 26093A DK 26093 A DK26093 A DK 26093A
Authority
DK
Denmark
Prior art keywords
procedure
preparation
acid salts
clavulanic acid
clavulanic
Prior art date
Application number
DK026093A
Other languages
English (en)
Other versions
DK26093D0 (da
Inventor
Franz Krenmueller
Harald Summer
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Publication of DK26093D0 publication Critical patent/DK26093D0/da
Publication of DK26093A publication Critical patent/DK26093A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D503/00Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
DK026093A 1992-03-10 1993-03-09 Fremgangsmaade til fremstilling af clavulansyresalte DK26093A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0047292A AT400033B (de) 1992-03-10 1992-03-10 Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben

Publications (2)

Publication Number Publication Date
DK26093D0 DK26093D0 (da) 1993-03-09
DK26093A true DK26093A (da) 1993-09-11

Family

ID=3491521

Family Applications (1)

Application Number Title Priority Date Filing Date
DK026093A DK26093A (da) 1992-03-10 1993-03-09 Fremgangsmaade til fremstilling af clavulansyresalte

Country Status (21)

Country Link
US (4) US20010036940A1 (da)
JP (2) JP2817563B2 (da)
CN (3) CN1045604C (da)
AT (1) AT400033B (da)
AU (1) AU659282B2 (da)
CH (1) CH685054A5 (da)
CY (1) CY1995A (da)
DE (1) DE4307422B4 (da)
DK (1) DK26093A (da)
ES (1) ES2058029B1 (da)
FI (1) FI101965B1 (da)
FR (1) FR2688506B1 (da)
GB (1) GB2264944B (da)
GR (1) GR1002329B (da)
HK (1) HK42696A (da)
IE (1) IE70926B1 (da)
IT (1) IT1261213B (da)
NL (1) NL9300430A (da)
NO (1) NO301372B1 (da)
SE (1) SE508043C2 (da)
TW (1) TW364907B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT399155B (de) * 1992-03-26 1995-03-27 Lek Tovarna Farmacevtskih Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) * 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
KR100200239B1 (ko) * 1992-10-21 1999-06-15 김충환 클라불란산 칼륨염의 제조방법
DK0658558T3 (da) 1993-11-17 2001-04-17 Biochemie Gmbh Adskillelse af cephalosporinisomere
GB9426261D0 (en) * 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts
MD1744F2 (ro) * 1995-02-25 2001-09-30 Spurcourt Limited Săruri ale acidului clavulanic şi procedeu de obţinere a lor
KR100200242B1 (ko) * 1995-05-16 1999-06-15 김충환 클라불란산염의 제조 방법
AT403375B (de) * 1995-11-15 1998-01-26 Biochemie Gmbh Verfahren zur fällung von alkalisalzen der clavulansäure
WO2000004028A1 (en) * 1998-07-16 2000-01-27 Dsm N.V. Improved process for the preparation of salts and esters of clavulanic acid
DE60008508T9 (de) * 1999-04-01 2012-06-14 Dsm Ip Assets B.V. Agglomerate durch kristallisation
MXPA02011192A (es) * 2000-05-13 2003-03-10 Smithkline Beecham Plc Procedimiento para la purificacion de una sal de acido clavulanico.
CA2621982C (en) * 2005-09-07 2017-11-28 Jennerex Biotherapeutics Ulc Systemic treatment of metastatic and/or systemically-disseminated cancers using gm-csf-expressing poxviruses
JP7028064B2 (ja) 2018-05-30 2022-03-02 横河電機株式会社 機器保全装置、機器保全方法、機器保全プログラム及び記録媒体
EP4178710A1 (en) 2020-07-10 2023-05-17 Carbon Clean Solutions Limited A method and system for the removal of carbon dioxide from solvents using low-grade heat

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3288800A (en) * 1962-05-29 1966-11-29 Squibb & Sons Inc Schiff's bases of 6-amino-penicillanic acid and purification of 6-aminopenicillanic acid by the use thereof
GB1508977A (en) 1974-04-20 1978-04-26 Beecham Group Ltd Beta-lactam antibiotic from streptomyces clavuligerus
US4110165A (en) * 1974-04-20 1978-08-29 Beecham Group Limited Process for the production of clavulanic acid
NZ177159A (en) * 1974-04-20 1978-03-06 Beecham Group Ltd Clavulanic acid, salts, esters and preparation thereof from streptomyces clavuligerus: pharmaceutical compositions
GB1543563A (en) 1975-02-07 1979-04-04 Glaxo Lab Ltd Beta-lactam antibiotic in purified form
US4144242A (en) * 1975-02-07 1979-03-13 Glaxo Laboratories Limited Process for the purification of clavulanic acid
GB1561395A (en) 1976-02-26 1980-02-20 Beecham Group Ltd -lactam antibiotic
GB1578739A (en) * 1976-07-23 1980-11-05 Beecham Group Ltd Amine salts of clavulanic acid methods for their preparation and compositions containing them
GB2003863B (en) 1977-09-01 1982-03-31 Beecham Group Ltd Chemical process
DE2861607D1 (en) 1977-11-26 1982-03-11 Beecham Group Plc Derivatives of clavulanic acid and pharmaceutical compositions containing them
BE862211A (fr) * 1977-12-22 1978-06-22 Beecham Group Ltd Agents antibacteriens
US4454069A (en) * 1979-08-24 1984-06-12 Beecham Group Limited Clavulanic acid salts and their preparation from the tertiary butyl amine salt
DE3063683D1 (en) * 1979-08-24 1983-07-14 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use
AR245221A1 (es) 1984-10-27 1993-12-30 Beecham Group Plc Un metodo para la produccion de acido clavulanico por fermentacion de s. clavuligerus
GB8618888D0 (en) * 1986-08-01 1986-09-10 Davy Mckee Ltd Process
ES2074048T3 (es) 1987-01-29 1995-09-01 Beecham Group Plc Procedimiento para la cristalizacion de clavulanato de potasio.
US5679789A (en) * 1987-01-29 1997-10-21 Beecham Group, P.L.C. Pharmaceutical compositions comprising potassium clavulanate and methods of using them
ES2010143A6 (es) * 1989-03-01 1989-10-16 Pharma Mar S A Pharmar Un nuevo procedimiento de obtencion del acido z(2r,5r)-3-(2-hiadroxietiliden)-7- oxo-4-oxa-1-azabiciclo(3,2,0) -heptano-2-carboxilico y de sales estares farmaceutiacamente aceptables del mismo,a partir de caldos de fermentacion de streptomyces, sp.
US5210296A (en) * 1990-11-19 1993-05-11 E. I. Du Pont De Nemours And Company Recovery of lactate esters and lactic acid from fermentation broth
AT399155B (de) * 1992-03-26 1995-03-27 Lek Tovarna Farmacevtskih Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
SI9200139A (en) * 1992-07-08 1994-03-31 Lek Tovarna Farmacevtskih New inclusion complex of clavulanic acid with hydrophylyc and hydropholyc beta-cyclodextrin derivates for production of them
KR100200239B1 (ko) 1992-10-21 1999-06-15 김충환 클라불란산 칼륨염의 제조방법
GB9401969D0 (en) 1994-02-02 1994-03-30 Smithkline Beecham Plc Process
SI9400107A (en) 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB2298201B (en) 1995-02-25 1997-05-28 Spurcourt Ltd Clavulanic acid salts
MD1744F2 (ro) * 1995-02-25 2001-09-30 Spurcourt Limited Săruri ale acidului clavulanic şi procedeu de obţinere a lor
SI9500074A (en) 1995-03-10 1996-10-31 Lek Tovarna Farmacevtskih Process for preparation of alkani salts of clavulanic acid.
SI9500134B (sl) 1995-04-20 2004-04-30 Lek, Postopek za pripravo čistih alkalijskih soli klavulanske kisline
KR100200242B1 (ko) * 1995-05-16 1999-06-15 김충환 클라불란산염의 제조 방법
GB9515809D0 (en) 1995-08-02 1995-10-04 Smithkline Beecham Plc Process
SI9500265A1 (en) 1995-08-28 1997-02-28 Lek Tovarna Farmacevtskih Process for purification of the aqueous fermented broth filtrate of streptomyces sp. p 6621 ferm p 2804 by ultrafiltration
ZA975198B (en) 1996-06-13 1997-12-15 Smithkline Beecham Corp Improved process for preparing potassium clavulanate.
JP2001503763A (ja) 1996-11-11 2001-03-21 ギスト ブロカデス ベスローテン フェンノートシャップ クラバラン酸の塩及びエステルの調製法

Also Published As

Publication number Publication date
CN1150153A (zh) 1997-05-21
GB2264944B (en) 1995-09-06
NO930829L (no) 1993-09-13
AU3407093A (en) 1993-09-16
JP2817563B2 (ja) 1998-10-30
USH2158H1 (en) 2006-06-06
FR2688506A1 (fr) 1993-09-17
ATA47292A (de) 1995-01-15
SE9300758D0 (sv) 1993-03-08
US20010036940A1 (en) 2001-11-01
AT400033B (de) 1995-09-25
IE70926B1 (en) 1997-01-15
ITRM930147A0 (it) 1993-03-10
IT1261213B (it) 1996-05-09
FI101965B (fi) 1998-09-30
DK26093D0 (da) 1993-03-09
FR2688506B1 (fr) 1995-06-23
GB9304704D0 (en) 1993-04-28
ITRM930147A1 (it) 1994-09-10
US20030203886A1 (en) 2003-10-30
ES2058029B1 (es) 1995-05-01
ES2058029A1 (es) 1994-10-16
FI931032A (fi) 1993-09-11
CN1079743A (zh) 1993-12-22
CN1145906A (zh) 1997-03-26
SE9300758L (sv) 1993-09-11
TW364907B (en) 1999-07-21
NO930829D0 (no) 1993-03-08
CY1995A (en) 1997-09-05
DE4307422B4 (de) 2004-11-25
GB2264944A (en) 1993-09-15
NL9300430A (nl) 1993-10-01
GR1002329B (el) 1996-05-15
DE4307422A1 (de) 1993-09-30
JPH1067785A (ja) 1998-03-10
HK42696A (en) 1996-03-22
IE930172A1 (en) 1993-09-22
GR930100090A (el) 1993-11-30
NO301372B1 (no) 1997-10-20
CN1045604C (zh) 1999-10-13
US20020072513A1 (en) 2002-06-13
SE508043C2 (sv) 1998-08-17
JPH0641143A (ja) 1994-02-15
US20030022882A1 (en) 2003-01-30
FI101965B1 (fi) 1998-09-30
AU659282B2 (en) 1995-05-11
CH685054A5 (de) 1995-03-15
FI931032A0 (fi) 1993-03-09

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Legal Events

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A0 Application filed
AHS Application shelved for other reasons than non-payment